-
1
-
-
84255195028
-
Regulating the regulator: Post-translational modification of RAS
-
Ahearn, I.M., Haigis, K., Bar-Sagi, D., and Philips, M.R. (2011). Regulating the regulator: post-translational modification of RAS. Nat. Rev. Mol. Cell Biol. 13, 39-51.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 39-51
-
-
Ahearn, I.M.1
Haigis, K.2
Bar-Sagi, D.3
Philips, M.R.4
-
2
-
-
77955016508
-
Thinner, smaller, faster: IR techniques to probe the functionality of biological and biomimetic systems
-
Ataka, K., Kottke, T., and Heberle, J. (2010). Thinner, smaller, faster: IR techniques to probe the functionality of biological and biomimetic systems. Angew. Chem. Int. Ed. 49, 5416-5424.
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 5416-5424
-
-
Ataka, K.1
Kottke, T.2
Heberle, J.3
-
3
-
-
0034642495
-
Bioorganic synthesis of lipid-modified proteins for the study of signal transduction
-
Bader, B., Kuhn, K., Owen, D.J., Waldmann, H., Wittinghofer, A., and Kuhlmann, J. (2000). Bioorganic synthesis of lipid-modified proteins for the study of signal transduction. Nat. Lond. 403, 223-226.
-
(2000)
Nat. Lond.
, vol.403
, pp. 223-226
-
-
Bader, B.1
Kuhn, K.2
Owen, D.J.3
Waldmann, H.4
Wittinghofer, A.5
Kuhlmann, J.6
-
4
-
-
0036880493
-
What vibrations tell about proteins
-
Barth, A. and Zscherp, C. (2002). What vibrations tell about proteins. Q. Rev. Biophys. 35, 369-430.
-
(2002)
Q. Rev. Biophys.
, vol.35
, pp. 369-430
-
-
Barth, A.1
Zscherp, C.2
-
5
-
-
0030949448
-
Time-resolved infrared spectroscopy of intermediates and products from photolysis of 1-(2-nitrophenyl)ethyl phosphates: Reaction of the 2-nitrosoacetophenone byproduct with Thiols
-
Barth, A., Corrie, E.T.J., Gradwell, M.J., Maeda, Y., Mäntele, W., Meier, T., and D.R. Trentham. (1997). Time-resolved infrared spectroscopy of intermediates and products from photolysis of 1-(2-nitrophenyl)ethyl phosphates: reaction of the 2-nitrosoacetophenone byproduct with Thiols. J. Am. Chem. Soc. 119, 4149-4159.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 4149-4159
-
-
Barth, A.1
-
6
-
-
77954763260
-
Tyr39 of Ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis
-
Brucker, S., Gerwert, K., and Kötting, C. (2010). Tyr39 of Ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis. J. Mol. Biol. 401, 1-6.
-
(2010)
J. Mol. Biol.
, vol.401
, pp. 1-6
-
-
Brucker, S.1
Gerwert, K.2
Kötting, C.3
-
7
-
-
0031799611
-
Fourier transform infrared photolysis studies of caged compounds
-
Cepus, V., Ulbrich, C., Allin, C., Troullier, A., and Gerwert, K. (1998). Fourier transform infrared photolysis studies of caged compounds. Methods Enzymol. 291, 223-245.
-
(1998)
Methods Enzymol.
, vol.291
, pp. 223-245
-
-
Cepus, V.1
Ulbrich, C.2
Allin, C.3
Troullier, A.4
Gerwert, K.5
-
8
-
-
33847780433
-
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach
-
Chakrabarti, P.P., Daumke, O., Suveyzdis, Y., Kötting, C., Gerwert, K., and Wittinghofer, A. (2007). Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach. J. Mol. Biol. 367, 983-995.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 983-995
-
-
Chakrabarti, P.P.1
Daumke, O.2
Suveyzdis, Y.3
Kötting, C.4
Gerwert, K.5
Wittinghofer, A.6
-
9
-
-
84874433733
-
Regulation of small GTPases by GEFs, GAPs, and GDIs
-
Cherfils, J. and Zeghouf, M. (2013). Regulation of Small GTPases by GEFs, GAPs, and GDIs. Physiol. Rev. 93, 269-309.
-
(2013)
Physiol. Rev.
, vol.93
, pp. 269-309
-
-
Cherfils, J.1
Zeghouf, M.2
-
10
-
-
78649474147
-
Ras history-The saga continues
-
Cox, A.D. and Der, C.J. (2010). Ras history-the saga continues. Small GTPases 1, 2-27.
-
(2010)
Small GTPases
, vol.1
, pp. 2-27
-
-
Cox, A.D.1
Der, C.J.2
-
11
-
-
33744500511
-
Enthalpies of hydration of N-methylacetamide by one, two, and three waters and the effect upon the C:O stretching frequency. An ab initio DFT study
-
Dannenberg, J.J. (2006). Enthalpies of hydration of N-methylacetamide by one, two, and three waters and the effect upon the C:O stretching frequency. An ab initio DFT study. J. Phys. Chem. A 110, 5798-5802.
-
(2006)
J. Phys. Chem.
, vol.A110
, pp. 5798-5802
-
-
Dannenberg, J.J.1
-
12
-
-
2442669194
-
The GTPase-activating protein Rap1GAP uses a catalytic asparagine
-
Daumke, O., Weyand, M., Chakrabarti, P.P., Vetter, I.R., and Wittinghofer, A. (2004). The GTPase-activating protein Rap1GAP uses a catalytic asparagine. Nature 429, 197-201.
-
(2004)
Nature
, vol.429
, pp. 197-201
-
-
Daumke, O.1
Weyand, M.2
Chakrabarti, P.P.3
Vetter, I.R.4
Wittinghofer, A.5
-
13
-
-
0000829940
-
Relationship between bond stretching frequencies and internal bonding for [O-16(4)]-and [O-18(4)]phosphates in aqueous solution
-
Deng, H., Wang, J.H., Callender, R., and Ray, W.J. (1998). Relationship between bond stretching frequencies and internal bonding for [O-16(4)]-and [O-18(4)]phosphates in aqueous solution. J. Phys. Chem. B 102, 3617-3623.
-
(1998)
J. Phys. Chem.
, vol.B102
, pp. 3617-3623
-
-
Deng, H.1
Wang, J.H.2
Callender, R.3
Ray, W.J.4
-
14
-
-
0021943979
-
Lightdriven protonation changes of internal aspartic acids of bacteriorhodopsin: An investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane
-
Engelhard, M., Gerwert, K., Hess, B., and Siebert, F. (1985). Lightdriven protonation changes of internal aspartic acids of bacteriorhodopsin: an investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane. Biochemistry (Mosc) 24, 400-407.
-
(1985)
Biochemistry (Mosc)
, vol.24
, pp. 400-407
-
-
Engelhard, M.1
Gerwert, K.2
Hess, B.3
Siebert, F.4
-
15
-
-
84856119703
-
Illuminating the functional and structural repertoire of human TBC/RABGAPs
-
Frasa, M.A.M., Koessmeier, K.T., Ahmadian, M.R., and Braga, V.M.M. (2012). Illuminating the functional and structural repertoire of human TBC/RABGAPs. Nat. Rev. Mol. Cell Biol. 13, 67-73.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 67-73
-
-
Frasa, M.A.M.1
Koessmeier, K.T.2
Ahmadian, M.R.3
Braga, V.M.M.4
-
16
-
-
84871838502
-
Catalytic mechanism of a mammalian RabRabGAP complex in atomic detail
-
Gavriljuk, K., Gazdag, E.-M., Itzen, A., Kötting, C., Goody, R.S., and Gerwert, K. (2012). Catalytic mechanism of a mammalian RabRabGAP complex in atomic detail. Proc. Natl. Acad. Sci. USA 109, 21348-21353.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 21348-21353
-
-
Gavriljuk, K.1
Gazdag, E.-M.2
Itzen, A.3
Kötting, C.4
Goody, R.S.5
Gerwert, K.6
-
17
-
-
84882307930
-
Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy
-
Gavriljuk, K., Itzen, A., Goody, R.S., Gerwert, K., and Kötting, C. (2013). Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy. Proc. Natl. Acad. Sci. USA 110, 13380-13385.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13380-13385
-
-
Gavriljuk, K.1
Itzen, A.2
Goody, R.S.3
Gerwert, K.4
Kötting, C.5
-
18
-
-
0030992130
-
Protein prenylation, et cetera-signal transduction in two dimensions
-
Gelb, M.H. (1997). Protein prenylation, et cetera-signal transduction in two dimensions. Science 275, 1750-1750.
-
(1997)
Science
, vol.275
, pp. 1750-1750
-
-
Gelb, M.H.1
-
19
-
-
0041453627
-
Intramolecular protein dynamics study with time-resolved Fourier-transform IR-difference spectroscopy
-
Gerwert, K. (1988). Intramolecular protein dynamics study with time-resolved Fourier-transform IR-difference spectroscopy. Berichte Bunsen-Ges 92, 978-982.
-
(1988)
Berichte Bunsen-Ges
, vol.92
, pp. 978-982
-
-
Gerwert, K.1
-
20
-
-
0027515417
-
Molecular reaction mechanisms of proteins as monitored by time-resolved FTIR spectroscopy
-
Gerwert, K. (1993). Molecular reaction mechanisms of proteins as monitored by time-resolved FTIR spectroscopy. Curr. Opin. Struct. Biol. i, 769-773.
-
(1993)
Curr. Opin. Struct. Biol.
, vol.1
, pp. 769-773
-
-
Gerwert, K.1
-
21
-
-
79551695493
-
Fourier transform infrared (FTIR) spectroscopy
-
(Chichester: John Wiley & Sons, Ltd.) DOI: 10.1
-
Gerwert, K. and Kötting, C. (2010). Fourier transform infrared (FTIR) spectroscopy. Encycl. Life Sci. (Chichester: John Wiley & Sons, Ltd.).
-
(2010)
Encycl. Life Sci.
-
-
Gerwert, K.1
Kötting, C.2
-
22
-
-
0000311181
-
Evidence for light-induced 13-cis, 14-s-cis, isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals
-
ub2 Gerwert, K. and Siebert, F. (1986). Evidence for light-induced 13-cis, 14-s-cis, isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals. EMBO J. 5, 805-811.
-
(1986)
EMBO J.
, vol.5
, pp. 805-811
-
-
Gerwert, K.1
Siebert, F.2
-
23
-
-
0024707259
-
Role of aspartate-96 in proton translocation by bacteriorhodopsin
-
Gerwert, K., Hess, B., Soppa, J., and Oesterhelt, D. (1989). Role of aspartate-96 in proton translocation by bacteriorhodopsin. Proc. Natl. Acad. Sci. USA 86, 4943-4947.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 4943-4947
-
-
Gerwert, K.1
Hess, B.2
Soppa, J.3
Oesterhelt, D.4
-
24
-
-
0025629995
-
Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy
-
Gerwert, K., Souvignier, G., and Hess, B. (1990). Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy. Proc. Natl. Acad. Sci. USA 87, 9774-9778.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 9774-9778
-
-
Gerwert, K.1
Souvignier, G.2
Hess, B.3
-
25
-
-
69249222742
-
Protein secondary structure content in solution, films and tissues: Redundancy and complementarity of the information content in circular dichroism, transmission and ATR FTIR spectra
-
Goormaghtigh, E., Gasper, R., Benard, A., Goldsztein, A., and Raussens, V. (2009). Protein secondary structure content in solution, films and tissues: redundancy and complementarity of the information content in circular dichroism, transmission and ATR FTIR spectra. Biochim. Biophys. Acta 1794, 1332-1343.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 1332-1343
-
-
Goormaghtigh, E.1
Gasper, R.2
Benard, A.3
Goldsztein, A.4
Raussens, V.5
-
26
-
-
33845985649
-
Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations
-
Grigorenko, B.L., Nemukhin, A.V., Shadrina, M.S., Topol, I.A., and Burt, S.K. (2007). Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations. Proteins Struct Funct Bioinform 66, 456-466.
-
(2007)
Proteins Struct Funct Bioinform
, vol.66
, pp. 456-466
-
-
Grigorenko, B.L.1
Nemukhin, A.V.2
Shadrina, M.S.3
Topol, I.A.4
Burt, S.K.5
-
27
-
-
84895725724
-
The importance of seeing surface (effects)
-
Gruschus, J.M., Byrd, R.A., and Randazzo, P.A. (2014). The importance of seeing surface (effects). Structure 22, 363-365.
-
(2014)
Structure
, vol.22
, pp. 363-365
-
-
Gruschus, J.M.1
Byrd, R.A.2
Randazzo, P.A.3
-
28
-
-
55949118981
-
Secondary structure of lipidated Ras bound to a lipid bilayer
-
Güldenhaupt, J., Adigüzel, Y., Kuhlmann, J., Waldmann, H., Kötting, C., and Gerwert, K. (2008). Secondary structure of lipidated Ras bound to a lipid bilayer. FEBS J. 275, 5910-5918.
-
(2008)
FEBS J.
, vol.275
, pp. 5910-5918
-
-
Güldenhaupt, J.1
Adigüzel, Y.2
Kuhlmann, J.3
Waldmann, H.4
Kötting, C.5
Gerwert, K.6
-
29
-
-
84867030014
-
N-Ras forms dimers at POPC membranes
-
Güldenhaupt, J., Rudack, T., Bachler, P., Mann, D., Triola, G., Waldmann, H., Kötting, C., and Gerwert, K. (2012). N-Ras forms dimers at POPC membranes. Biophys. J. 103, 1585-1593.
-
(2012)
Biophys. J.
, vol.103
, pp. 1585-1593
-
-
Güldenhaupt, J.1
Rudack, T.2
Bachler, P.3
Mann, D.4
Triola, G.5
Waldmann, H.6
Kötting, C.7
Gerwert, K.8
-
30
-
-
0038637862
-
Amide i modes in the N-methylacetamide dimer and glycine dipeptide analog: Diagonal force constants
-
Ham, S. and Cho, M. (2003). Amide I modes in the N-methylacetamide dimer and glycine dipeptide analog: diagonal force constants. J. Chem. Phys. 118, 6915.
-
(2003)
J. Chem. Phys.
, vol.118
, pp. 6915
-
-
Ham, S.1
Cho, M.2
-
31
-
-
61449215145
-
Ras acylation, compartmentalization and signaling nanoclusters (review)
-
Henis, Y.I., Hancock, J.F., and Prior, I.A. (2009). Ras acylation, compartmentalization and signaling nanoclusters (review). Mol. Membr. Biol. 26, 80-92.
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 80-92
-
-
Henis, Y.I.1
Hancock, J.F.2
Prior, I.A.3
-
33
-
-
0027429642
-
A model-independent approach to assigning bacteriorhodopsin's intramolecular reactions to photocycle intermediates
-
Hessling, B., Souvignier, G., and Gerwert, K. (1993). A model-independent approach to assigning bacteriorhodopsin's intramolecular reactions to photocycle intermediates. Biophys. J. 65, 1929-1941.
-
(1993)
Biophys. J.
, vol.65
, pp. 1929-1941
-
-
Hessling, B.1
Souvignier, G.2
Gerwert, K.3
-
34
-
-
81255162437
-
-
The Enzymes Elsevier: Amsterdam, The Netherlands
-
Hodges-Loaiza, H.B., Parker, L.E., and Cox, A.D. (2011). Prenylation and Phosphorylation of Ras Superfamily Small GTPases. The Enzymes (Elsevier: Amsterdam, The Netherlands), pp. 43-69.
-
(2011)
Prenylation and Phosphorylation of Ras Superfamily Small GTPases
, pp. 43-69
-
-
Hodges-Loaiza, H.B.1
Parker, L.E.2
Cox, A.D.3
-
35
-
-
84873687488
-
Anharmonic vibrational frequency calculations are not worthwhile for small basis sets
-
Jacobsen, R.L., Johnson, R.D., Irikura, K.K., and Kacker, R.N. (2013). Anharmonic vibrational frequency calculations are not worthwhile for small basis sets. J. Chem. Theory Comput. 9, 951-954.
-
(2013)
J. Chem. Theory Comput.
, vol.9
, pp. 951-954
-
-
Jacobsen, R.L.1
Johnson, R.D.2
Irikura, K.K.3
Kacker, R.N.4
-
36
-
-
79952578312
-
Nuclear pore complex
-
Jamali, T., Jamali, Y., Mehrbod, M., and Mofrad, M.R.K. (2011). Nuclear pore complex. Int. Rev. Cell Mol. Biol. 287, 233-286.
-
(2011)
Int. Rev. Cell Mol. Biol.
, vol.287
, pp. 233-286
-
-
Jamali, T.1
Jamali, Y.2
Mehrbod, M.3
Mofrad, M.R.K.4
-
37
-
-
84881414181
-
Structural biology of Arf and Rab GTPases' effector recruitment and specificity
-
Khan, A.R. and Ménétrey, J. (2013). Structural biology of Arf and Rab GTPases' effector recruitment and specificity. Structure 21, 1284-1297.
-
(2013)
Structure
, vol.21
, pp. 1284-1297
-
-
Khan, A.R.1
Ménétrey, J.2
-
38
-
-
84872237121
-
Photoremovable pro tecting groups in chemistry and biology: Reaction mechanisms and efficacy
-
Klán, P., Šolomek, T., Bochet, C.G., Blanc, A., Givens, R., Rubina, M., Popik, V., Kostikov, A., and Wirz, J. (2013). Photoremovable pro tecting groups in chemistry and biology: reaction mechanisms and efficacy. Chem. Rev. 113, 119-191.
-
(2013)
Chem. Rev.
, vol.113
, pp. 119-191
-
-
Klán, P.1
Šolomek, T.2
Bochet, C.G.3
Blanc, A.4
Givens, R.5
Rubina, M.6
Popik, V.7
Kostikov, A.8
Wirz, J.9
-
39
-
-
8644238262
-
Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions
-
Kötting, C. and Gerwert, K. (2004). Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions. Chem. Phys. 307, 227-232.
-
(2004)
Chem. Phys.
, vol.307
, pp. 227-232
-
-
Kötting, C.1
Gerwert, K.2
-
40
-
-
18744379142
-
Proteins in action monitored by time-resolved FTIR spectroscopy
-
Kötting, C. and Gerwert, K. (2005a). Proteins in action monitored by time-resolved FTIR spectroscopy. ChemPhysChem 6, 881-888.
-
(2005)
Chem Phys Chem
, vol.6
, pp. 881-888
-
-
Kötting, C.1
Gerwert, K.2
-
41
-
-
84889397226
-
Monitoring protein-protein interactions by time-resolved FTIR difference spectroscopy
-
E. Golemis and P. Adams, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harb Lab Press
-
Kötting, C. and Gerwert, K. (2005b). Monitoring protein-protein interactions by time-resolved FTIR difference spectroscopy. In: Protein-Protein Interact, 2nd Ed, E. Golemis and P. Adams, eds. (Cold Spring Harbor, NY, USA: Cold Spring Harb Lab Press) pp. 279-299.
-
(2005)
Protein-Protein Interact, 2nd Ed
, pp. 279-299
-
-
Kötting, C.1
Gerwert, K.2
-
42
-
-
84878952932
-
The dynamics of the catalytic site in small GTPases, variations on a common motif
-
Kötting, C. and Gerwert, K. (2013). The dynamics of the catalytic site in small GTPases, variations on a common motif. FEBS Lett. 587, 2025-2027.
-
(2013)
FEBS Lett.
, vol.587
, pp. 2025-2027
-
-
Kötting, C.1
Gerwert, K.2
-
43
-
-
33749014394
-
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein
-
Kötting, C., Blessenohl, M., Suveyzdis, Y., Goody, R.S., Wittinghofer, A., and Gerwert, K. (2006). A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein. Proc. Natl. Acad. Sci. USA 103, 13911-13916.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13911-13916
-
-
Kötting, C.1
Blessenohl, M.2
Suveyzdis, Y.3
Goody, R.S.4
Wittinghofer, A.5
Gerwert, K.6
-
44
-
-
34250835961
-
Surface change of Ras enabling effector binding monitored in real time at atomic resolution
-
Kötting, C., Kallenbach, A., Suveyzdis, Y., Eichholz, C., and Gerwert, K. (2007). Surface change of Ras enabling effector binding monitored in real time at atomic resolution. ChemBio-Chem 8, 781-787.
-
(2007)
ChemBio-Chem
, vol.8
, pp. 781-787
-
-
Kötting, C.1
Kallenbach, A.2
Suveyzdis, Y.3
Eichholz, C.4
Gerwert, K.5
-
45
-
-
44049093161
-
The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy
-
Kötting, C., Kallenbach, A., Suveyzdis, Y., Wittinghofer, A., and Gerwert, K. (2008). The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy. Proc. Natl. Acad. Sci. USA 105, 6260-6265.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6260-6265
-
-
Kötting, C.1
Kallenbach, A.2
Suveyzdis, Y.3
Wittinghofer, A.4
Gerwert, K.5
-
46
-
-
77957686511
-
Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions
-
Kötting, C., Suveyzdis, Y., Bojja, R.S., Metzler-Nolte, N., and Gerwert, K. (2010). Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions. Appl. Spectrosc. 64, 967-972.
-
(2010)
Appl. Spectrosc.
, vol.64
, pp. 967-972
-
-
Kötting, C.1
Suveyzdis, Y.2
Bojja, R.S.3
Metzler-Nolte, N.4
Gerwert, K.5
-
47
-
-
84857848058
-
Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer
-
Kötting, C., Güldenhaupt, J., and Gerwert, K. (2012). Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer. Chem. Phys. 396, 72-83.
-
(2012)
Chem. Phys.
, vol.396
, pp. 72-83
-
-
Kötting, C.1
Güldenhaupt, J.2
Gerwert, K.3
-
48
-
-
33744511934
-
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins
-
Kupzig, S., Deaconescu, D., Bouyoucef, D., Walker, S.A., Liu, Q., Polte, C.L., Daumke, O., Ishizaki, T., Lockyer, P.J., Wittinghofer, A., et al. (2006). GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins. J. Biol. Chem. 281, 9891-9900.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9891-9900
-
-
Kupzig, S.1
Deaconescu, D.2
Bouyoucef, D.3
Walker, S.A.4
Liu, Q.5
Polte, C.L.6
Daumke, O.7
Ishizaki, T.8
Lockyer, P.J.9
Wittinghofer, A.10
-
49
-
-
84856733759
-
Inhibition and termination of physiological responses by GTPase activating proteins
-
Ligeti, E., Welti, S., and Scheffzek, K. (2012). Inhibition and termination of physiological responses by GTPase activating proteins. Physiol. Rev. 92, 237-272.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 237-272
-
-
Ligeti, E.1
Welti, S.2
Scheffzek, K.3
-
50
-
-
84896840047
-
H-Ras forms dimers on membrane surfaces via a protein-protein interface
-
Lin, W.-C., Iversen, L., Tu, H.-L., Rhodes, C., Christensen, S.M., Iwig, J.S., Hansen, S.D., Huang, W.Y., and Groves, J.T. (2014). H-Ras forms dimers on membrane surfaces via a protein-protein interface. Proc. Natl. Acad. Sci. USA 111, 2996-3001.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 2996-3001
-
-
Lin, W.-C.1
Iversen, L.2
Tu, H.-L.3
Rhodes, C.4
Christensen, S.M.5
Iwig, J.S.6
Hansen, S.D.7
Huang, W.Y.8
Groves, J.T.9
-
51
-
-
62349138654
-
Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR
-
Marshall, C.B., Ho, J., Buerger, C., Plevin, M.J., Li, G.Y., Li, Z., Ikura, M., and Stambolic, V. (2009). Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR. Sci. Signal 2, ra3.
-
(2009)
Sci. Signal
, vol.2
, pp. ra3
-
-
Marshall, C.B.1
Ho, J.2
Buerger, C.3
Plevin, M.J.4
Li, G.Y.5
Li, Z.6
Ikura, M.7
Stambolic, V.8
-
52
-
-
84898732623
-
Mutant enzymes challenge all assumptions
-
Nottingham, R.M. and Pfeffer, S.R. (2014). Mutant enzymes challenge all assumptions. eLife 3, e02171.
-
(2014)
ELife
, vol.3
, pp. e02171
-
-
Nottingham, R.M.1
Pfeffer, S.R.2
-
53
-
-
33746356908
-
TBCdomain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism
-
Pan, X.J., Eathiraj, S., Munson, M., and Lambright, D.G. (2006). TBCdomain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Nature 442, 303-306.
-
(2006)
Nature
, vol.442
, pp. 303-306
-
-
Pan, X.J.1
Eathiraj, S.2
Munson, M.3
Lambright, D.G.4
-
54
-
-
0037426364
-
The Mechanism of Ras GTPase activation by neurofibromin
-
Phillips, R.A., Hunter, J.L., Eccleston, J.F., and Webb, M.R. (2003). The Mechanism of Ras GTPase activation by neurofibromin. Biochemistry (Mosc) 42, 3956-3965.
-
(2003)
Biochemistry (Mosc)
, vol.42
, pp. 3956-3965
-
-
Phillips, R.A.1
Hunter, J.L.2
Eccleston, J.F.3
Webb, M.R.4
-
55
-
-
84864410997
-
Surface-attached polyhistidine-Tag proteins characterized by FTIR difference spectroscopy
-
Pinkerneil, P., Güldenhaupt, J., Gerwert, K., and Kötting, C. (2012). Surface-attached polyhistidine-Tag proteins characterized by FTIR difference spectroscopy. ChemPhysChem 13, 2649-2653.
-
(2012)
ChemPhysChem
, vol.13
, pp. 2649-2653
-
-
Pinkerneil, P.1
Güldenhaupt, J.2
Gerwert, K.3
Kötting, C.4
-
56
-
-
84905822657
-
Overview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras
-
Prakash, P. and Gorfe, A.A. (2014). Overview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras. Mol. Simul. 40, 839-847.
-
(2014)
Mol. Simul.
, vol.40
, pp. 839-847
-
-
Prakash, P.1
Gorfe, A.A.2
-
57
-
-
20144375061
-
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
-
Rocks, O., Peyker, A., and Kahms, M., Verveer, P.J., Koerner, C., Lumbierres, M., Kuhlmann, J., Waldmann, H., Wittinghofer, A., and Bastiaens, P.I. (2005). An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 307, 1746-1752.
-
(2005)
Science
, vol.307
, pp. 1746-1752
-
-
Rocks, O.1
Peyker, A.2
Kahms, M.3
Verveer, P.J.4
Koerner, C.5
Lumbierres, M.6
Kuhlmann, J.7
Waldmann, H.8
Wittinghofer, A.9
Bastiaens, P.I.10
-
58
-
-
84864759029
-
The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations
-
Rudack, T., Xia, F., Schlitter, J., Kötting, C., and Gerwert, K. (2012a). The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations. Biophys. J. 103, 293-302.
-
(2012)
Biophys. J.
, vol.103
, pp. 293-302
-
-
Rudack, T.1
Xia, F.2
Schlitter, J.3
Kötting, C.4
Gerwert, K.5
-
59
-
-
84866534653
-
Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations
-
Rudack, T., Xia, F., Schlitter, J., Kötting, C., and Gerwert, K. (2012b). Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations. Proc. Natl. Acad. Sci. USA 109, 15295-15300.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 15295-15300
-
-
Rudack, T.1
Xia, F.2
Schlitter, J.3
Kötting, C.4
Gerwert, K.5
-
60
-
-
84900564509
-
Dimerization opens new avenues into Ras signaling research
-
Santos, E. (2014). Dimerization opens new avenues into Ras signaling research. Sci. Signal 7, pe12.
-
(2014)
Sci. Signal
, vol.7
, pp. 12
-
-
Santos, E.1
-
61
-
-
84874960694
-
Universal method for protein immobilization on chemically functionalized germanium investigated by ATR-FTIR difference spectroscopy
-
Schartner, J., Güldenhaupt, J., Mei, B., Rögner, M., Muhler, M., Gerwert, K., and Kötting, C. (2013). Universal method for protein immobilization on chemically functionalized germanium investigated by ATR-FTIR difference spectroscopy. J. Am. Chem. Soc. 135, 4079-4087.
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 4079-4087
-
-
Schartner, J.1
Güldenhaupt, J.2
Mei, B.3
Rögner, M.4
Muhler, M.5
Gerwert, K.6
Kötting, C.7
-
62
-
-
0024396852
-
Biochemical and crystallographic characterization of a complex of C-Ha-Ras P21 and caged Gtp with flash-photolysis-(time-resolved structure)
-
Schlichting, I., Rapp, G., John, J., Wittinghofer, A., Pai, E.F., and Goody, R.S. (1989). Biochemical and crystallographic characterization of a complex of C-Ha-Ras P21 and caged Gtp with flash-photolysis-(time-resolved structure). Proc. Natl. Acad. Sci. USA 86, 7687-7690.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7687-7690
-
-
Schlichting, I.1
Rapp, G.2
John, J.3
Wittinghofer, A.4
Pai, E.F.5
Goody, R.S.6
-
63
-
-
41949114173
-
The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues
-
Scrima, A., Thomas, C., Deaconescu, D., and Wittinghofer, A. (2008). The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues. EMBO J. 27, 1145-1153.
-
(2008)
EMBO J.
, vol.27
, pp. 1145-1153
-
-
Scrima, A.1
Thomas, C.2
Deaconescu, D.3
Wittinghofer, A.4
-
65
-
-
0020603954
-
Fourier-transform infrared spectroscopy applied to rhodopsin. The problem of the protonation state of the retinylidene Schiff base reinvestigated
-
Siebert, F., Maentele, W., and Gerwert, K. (1983). Fourier-transform infrared spectroscopy applied to rhodopsin. The problem of the protonation state of the retinylidene Schiff base reinvestigated. Eur. J. Biochem. 136, 119-127.
-
(1983)
Eur. J. Biochem.
, vol.136
, pp. 119-127
-
-
Siebert, F.1
Maentele, W.2
Gerwert, K.3
-
66
-
-
79952779502
-
Rho GTPases and their role in organizing the actin cytoskeleton
-
Sit, S.-T. and Manser, E. (2011). Rho GTPases and their role in organizing the actin cytoskeleton. J. Cell Sci. 124, 679-683.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 679-683
-
-
Sit, S.-T.1
Manser, E.2
-
67
-
-
77950535099
-
Unravelling the mechanism of dualspecificity GAPs
-
Sot, B., Kötting, C., Deaconescu, D., Suveyzdis, Y., Gerwert, K., and Wittinghofer, A. (2010). Unravelling the mechanism of dualspecificity GAPs. EMBO J. 29, 1205-1214.
-
(2010)
EMBO J.
, vol.29
, pp. 1205-1214
-
-
Sot, B.1
Kötting, C.2
Deaconescu, D.3
Suveyzdis, Y.4
Gerwert, K.5
Wittinghofer, A.6
-
68
-
-
68049105101
-
Rab GTPases as coordinators of vesicle traffic
-
Stenmark, H. (2009). Rab GTPases as coordinators of vesicle traffic. Nat. Rev. Mol. Cell Biol. 10, 513-525.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 513-525
-
-
Stenmark, H.1
-
69
-
-
47949124438
-
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
-
Stieglitz, B., Bee, C., Schwarz, D., Yildiz, O., Moshnikova, A., Khokhlatchev, A., and Herrmann, C. (2008). Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II. EMBO J. 27, 1995-2005.
-
(2008)
EMBO J.
, vol.27
, pp. 1995-2005
-
-
Stieglitz, B.1
Bee, C.2
Schwarz, D.3
Yildiz, O.4
Moshnikova, A.5
Khokhlatchev, A.6
Herrmann, C.7
-
70
-
-
0035834388
-
Signal transduction-The guanine nucleotide-binding switch in three dimensions
-
Vetter, I.R. and Wittinghofer, A. (2001). Signal transduction-the guanine nucleotide-binding switch in three dimensions. Science 294, 1299-1304.
-
(2001)
Science
, vol.294
, pp. 1299-1304
-
-
Vetter, I.R.1
Wittinghofer, A.2
-
71
-
-
84885158575
-
Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin
-
Wang, Y., Pascoe, H.G., Brautigam, C.A., He, H., and Zhang, X. (2013). Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin. eLife 2, e01279.
-
(2013)
ELife
, vol.2
, pp. e01279
-
-
Wang, Y.1
Pascoe, H.G.2
Brautigam, C.A.3
He, H.4
Zhang, X.5
-
72
-
-
48849084900
-
Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy
-
Warscheid, B., Brucker, S., Kallenbach, A., Meyer, H.E., Gerwert, K., and Kötting, C. (2008). Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy. Vib. Spectrosc. 48, 28-36.
-
(2008)
Vib. Spectrosc.
, vol.48
, pp. 28-36
-
-
Warscheid, B.1
Brucker, S.2
Kallenbach, A.3
Meyer, H.E.4
Gerwert, K.5
Kötting, C.6
-
73
-
-
79959393264
-
Structure-function relationships of the G domain, a canonical switch motif
-
Wittinghofer, A. and Vetter, I.R. (2011). Structure-function relationships of the G domain, a canonical switch motif. Annu. Rev. Biochem. 80, 943-971.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 943-971
-
-
Wittinghofer, A.1
Vetter, I.R.2
-
74
-
-
77953809435
-
Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes
-
Wu, Y.-W., Oesterlin, L.K., Tan, K.-T., Waldmann, H., Alexandrov, K, and Goody, R.S. (2010). Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. Nat. Chem. Biol. 6, 534-540.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 534-540
-
-
Wu, Y.-W.1
Oesterlin, L.K.2
Tan, K.-T.3
Waldmann, H.4
Alexandrov, K.5
Goody, R.S.6
-
75
-
-
84870903225
-
Detailed structure of the H2PO4-guanosine diphosphate intermediate in Ras-GAP decoded from FTIR experiments by biomolecular simulations
-
Xia, F., Rudack, T., Cui, Q., Kötting, C., and Gerwert, K. (2012). Detailed structure of the H2PO4-guanosine diphosphate intermediate in Ras-GAP decoded from FTIR experiments by biomolecular simulations. J. Am. Chem. Soc. 134, 20041-20044.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 20041-20044
-
-
Xia, F.1
Rudack, T.2
Cui, Q.3
Kötting, C.4
Gerwert, K.5
|