Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 52, 2012, Pages 21348-21353

  Gavriljuk, Konstantin ^a   Gazdag, Emerich Mihai ^b   Itzen, Aymelt ^b,c   Koẗting, Carsten ^a   Goody, Roger S ^b   Gerwert, Klaus ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Dual finger; Enzyme catalysis; GTP hydrolysis; Isotopic labeling

Indexed keywords

GLUTAMINE; RAB GTPASE ACTIVATING PROTEIN; RAB PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; HUMAN; HYDROLYSIS; INFRARED SPECTROSCOPY; MAMMAL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; X RAY;

ANIMALS; BIOCATALYSIS; CATALYTIC DOMAIN; DNA MUTATIONAL ANALYSIS; GLUTAMINE; GTPASE-ACTIVATING PROTEINS; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; KINETICS; MAMMALS; MODELS, MOLECULAR; RAB1 GTP-BINDING PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

MAMMALIA;

EID: 84871838502     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214431110     Document Type: Article

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