Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice

Hepatology

Volumn 61, Issue 1, 2015, Pages 348-360

  Marques, Pedro Elias ^a   Oliveira, André Gustavo ^a   Pereira, Rafaela Vaz ^a   David, Bruna Araújo ^a   Gomides, Lindisley Ferreira ^a   Saraiva, Adriana Machado ^a   Pires, Daniele Araújo ^a   Novaes, Júlia Tosta ^a   Patricio, Daniel O ^b   Cisalpino, Daniel ^a   Menezes Garcia, Zélia ^b   Leevy, W Matthew ^c   Chapman, Sarah Ellen ^c   Mahecha, Germánarturo ^a   Marques, Rafael Elias ^a   Guabiraba, Rodrigo ^d   Martins, Vicente Paulo ^e   Souza, Danielle Gloria ^a   Mansur, Daniel Santos ^b   Teixeira, Mauro Martins ^d   Leite, M Fatima ^a   Menezes, Gustavo Batista ^a   more..

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^c UNIVERSITY OF NOTRE DAME   (United States)

^d UR1282   (France)

^e UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PARACETAMOL; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; THIOACETAMIDE; TOLL LIKE RECEPTOR 9; ANALGESIC AGENT; TLR9 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; FLOW CYTOMETRY; IN VITRO STUDY; INNATE IMMUNITY; LEUKOCYTE; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; TOXIC HEPATITIS; UPREGULATION; WILD TYPE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; IMMUNOLOGY; LEUKOCYTE ACTIVATION; LIVER; LIVER CELL; METABOLISM;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; DNA; DRUG-INDUCED LIVER INJURY; HEPATOCYTES; LIVER; MICE, INBRED C57BL; NEUTROPHIL ACTIVATION; NEUTROPHILS; TOLL-LIKE RECEPTOR 9;

EID: 84920956752     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27216     Document Type: Article

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