Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-α initiated p38 MAPK and NF-κB pathways

Clinical Immunology

Volumn 156, Issue 2, 2015, Pages 141-153

  Zhu, Wenhua ^a,b   Jiang, Congshan ^a,b   Xu, Jing ^a   Geng, Manman ^a   Wu, Xiaoying ^a   Sun, Jian ^a,b   Ma, Jie ^a,b   Holmdahl, Rikard ^c   Meng, Liesu ^a,b   Lu, Shemin ^a,b  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cytokines; Experimental arthritis; Fibroblast like synoviocyte; T cells; TLR3

Indexed keywords

COLLAGENASE 3; ETANERCEPT; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PRISTANE; STROMELYSIN; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR ALPHA; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CULTURE MEDIUM; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; MMP13 PROTEIN, RAT; NITRILE; PYRIDINE DERIVATIVE; SULFONE; TERPENE; TLR3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CD4+ T LYMPHOCYTE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; EX VIVO STUDY; FIBROBLAST; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPLEEN; SYNOVIOCYTE; T LYMPHOCYTE; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHEMICALLY INDUCED; CULTURE MEDIUM; CYTOLOGY; EXPERIMENTAL ARTHRITIS; GENETICS; IMMUNOLOGY; PHARMACOLOGY; SYNOVIUM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CULTURE MEDIA, CONDITIONED; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; IMMUNOSUPPRESSIVE AGENTS; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-6; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; NF-KAPPA B; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RATS; RNA, MESSENGER; SULFONES; SYNOVIAL MEMBRANE; TERPENES; TOLL-LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84920929252     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.11.008     Document Type: Article

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