Methotrexate ameliorates pristane-induced arthritis by decreasing IFN-γ and IL-17A expressions

Journal of Zhejiang University: Science B

Volumn 12, Issue 1, 2011, Pages 40-46

  Hou, Wei Kun ^a   Meng, Lie Su ^a   Zheng, Fang ^a   Wen, Yu Rong ^a   Zhu, Wen Hua ^a   Jiang, Cong Shan ^a   He, Xiao Jing ^a   Zhou, Yan ^a   Lu, She Min ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Black seed oil (BSO); Interferon (IFN ); Interleukin 17A (IL 17A); Methotrexate (MTX); Pristane induced arthritis (PIA)

Indexed keywords

BLACK SEED OIL; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 4; MESSENGER RNA; METHOTREXATE; NITRIC OXIDE; PRISTANE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DRUG EFFICACY; DRUG MEGADOSE; GENE EXPRESSION; INBRED STRAIN; INJECTION; LOW DRUG DOSE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PRISTANE INDUCED ARTHRITIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; BASE SEQUENCE; FEMALE; GENE EXPRESSION; INTERFERON-GAMMA; INTERLEUKIN-17; JOINTS; MALE; METHOTREXATE; NITRIC OXIDE; PLANT OILS; RATS; RATS, INBRED STRAINS; RNA, MESSENGER; SPLEEN; TERPENES;

AGOUTI; RATTUS;

EID: 79251554984     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1000078     Document Type: Article

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