Microbial Toll-like receptor ligands differentially regulate CXCL10/IP-10 expression in fibroblasts and mononuclear leukocytes in synergy with IFN-γ and provide a mechanism for enhanced synovial chemokine levels in septic arthritis

European Journal of Immunology

Volumn 33, Issue 11, 2003, Pages 3146-3153

  Proost, Paul ^a   Vynckier, An Katrien ^a   Mahieu, Frank ^a   Put, Willy ^a   Grillet, Bernard ^a,b   Struyf, Sofie ^a   Wuyts, Anja ^a   Opdenakker, Ghislain ^a   Van Damme, Jo ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b Ziekenhuis Zeeuws Vlaanderen   (Netherlands)

Author keywords

Arthritis; Bacterial peptidoglycan; Chemokine; Lipopolysaccharide; Toll like receptors

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; CHEMOKINE RECEPTOR CXCR3; DOUBLE STRANDED RNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ARTICLE; BACTERIAL ARTHRITIS; CONTROLLED STUDY; CROSS REACTION; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; LEUKOCYTE; MOLECULAR MECHANICS; NATURAL KILLER CELL; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

ARTHRITIS, INFECTIOUS; CHEMOKINES, CXC; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERFERON TYPE II; INTERLEUKIN-8; LEUKOCYTES, MONONUCLEAR; LIGANDS; MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; SYNOVIAL FLUID; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0242391978     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324136     Document Type: Article

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