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1
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22144455050
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Attention-deficit hyperactivity disorder
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PID: 16023516
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Biederman J, Faraone SV. Attention-deficit hyperactivity disorder. Lancet. 2005;366(9481):237–48.
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Lancet
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Biederman, J.1
Faraone, S.V.2
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2
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84881165061
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Attention-deficit hyperactivity disorder and the shifting sands of psychiatric nosology
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Faraone SV. Attention-deficit hyperactivity disorder and the shifting sands of psychiatric nosology. Br J Psychiatr. 2013;203(2):81–3.
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Br J Psychiatr
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Faraone, S.V.1
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3
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77149136734
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Molecular genetics of attention deficit hyperactivity disorder
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Faraone SV, Mick E. Molecular genetics of attention deficit hyperactivity disorder. Psychiatr Clin N Am. 2010;33(1):159–80.
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Psychiatr Clin N Am
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Faraone, S.V.1
Mick, E.2
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4
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84875887240
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Genetics of attention-deficit/hyperactivity disorder: current findings and future directions
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PID: 23545057, COI: 1:CAS:528:DC%2BC3sXltVyitbs%3D, This is an exhaustive review on the genetics studies in ADHD. It summarized that all variants associated with the pathology explain only a small fraction of heritability: phenotype complexity and variants of small effect contribute to the missing heritability issue
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Akutagava-Martins GC, Salatino-Oliveira A, Kieling CC, Rohde LA, Hutz MH. Genetics of attention-deficit/hyperactivity disorder: current findings and future directions. Expert Rev Neurother. 2013;13(4):435–45. This is an exhaustive review on the genetics studies in ADHD. It summarized that all variants associated with the pathology explain only a small fraction of heritability: phenotype complexity and variants of small effect contribute to the missing heritability issue.
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(2013)
Expert Rev Neurother
, vol.13
, Issue.4
, pp. 435-445
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Akutagava-Martins, G.C.1
Salatino-Oliveira, A.2
Kieling, C.C.3
Rohde, L.A.4
Hutz, M.H.5
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5
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2942750240
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The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry
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PID: 15163244
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Gould TD, Manji HK. The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry. J Clin Psychiatry. 2004;65(5):598–604.
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(2004)
J Clin Psychiatry
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, pp. 598-604
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Gould, T.D.1
Manji, H.K.2
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6
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84920927843
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Insel T (2013) Director’s Blog: transforming diagnosis
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Insel T (2013) Director’s Blog: transforming diagnosis. http://www.nimh.nih.gov/about/director/2013/transforming-diagnosis.shtml
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7
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0035100888
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Biomarkers and surrogate endpoints preferred definitions and conceptual framework
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Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints preferred definitions and conceptual framework. Clin Pharmacol Ther. 2001;69:89–95.
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(2001)
Clin Pharmacol Ther
, vol.69
, pp. 89-95
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Biomarkers Definitions Working Group1
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8
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67650459886
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Biomarkers in psychiatry
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PID: 19587761, COI: 1:CAS:528:DC%2BD1MXotlSnt7g%3D
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Singh I, Rose N. Biomarkers in psychiatry. Nature. 2009;460(7252):202–7.
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Nature
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, pp. 202-207
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Singh, I.1
Rose, N.2
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9
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84938984909
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Sokolowska I, Ngounou Wetie AG, Wormwood K, Thome J, Darie CC, Woods AG. The potential of biomarkers in psychiatry: focus on proteomics. J Neural Transm. 2013 Dec 20. This is a review on the importance to use the proteomics to identify biomarkers for different psychiatric pathologies including ADHD
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Sokolowska I, Ngounou Wetie AG, Wormwood K, Thome J, Darie CC, Woods AG. The potential of biomarkers in psychiatry: focus on proteomics. J Neural Transm. 2013 Dec 20. doi:10.1007/s00702-013-1134-6. This is a review on the importance to use the proteomics to identify biomarkers for different psychiatric pathologies including ADHD.
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10
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84864405643
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Biomarkers for attention-deficit/hyperactivity disorder (ADHD). A consensus report of the WFSBP task force on biological markers and the World Federation of ADHD
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PID: 22834452, This is a comprehensive review on clinical, imaging, genetic and proteomic markers and ADHD. The review concluded that, although some promising candidates such as olfactory sensitivity, substantial echogenicity, no biomarkers for ADHD are available
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Thome J, Ehlis AC, Fallgatter AJ, Krauel K, Lange KW, Riederer P, et al. Biomarkers for attention-deficit/hyperactivity disorder (ADHD). A consensus report of the WFSBP task force on biological markers and the World Federation of ADHD. World J Biol Psychiatry. 2012;13(5):379–400. This is a comprehensive review on clinical, imaging, genetic and proteomic markers and ADHD. The review concluded that, although some promising candidates such as olfactory sensitivity, substantial echogenicity, no biomarkers for ADHD are available.
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(2012)
World J Biol Psychiatry
, vol.13
, Issue.5
, pp. 379-400
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Thome, J.1
Ehlis, A.C.2
Fallgatter, A.J.3
Krauel, K.4
Lange, K.W.5
Riederer, P.6
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11
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77953438264
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Biomarkers in psychiatry: drawbacks and potential for misuse
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PID: 20150988
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Lakhan SE, Vieira K, Hamlat E. Biomarkers in psychiatry: drawbacks and potential for misuse. Int Arch Med. 2010;3:1.
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(2010)
Int Arch Med
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Lakhan, S.E.1
Vieira, K.2
Hamlat, E.3
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12
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65549142100
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Beyond reliability: biomarkers and validity in psychiatry
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Pies R. Beyond reliability: biomarkers and validity in psychiatry. Psychiatry (Edgmont). 2008;5(1):48–52.
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(2008)
Psychiatry (Edgmont)
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, pp. 48-52
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Pies, R.1
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13
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67651121684
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Candidate gene studies of ADHD: a meta-analytic review
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PID: 19506906, COI: 1:CAS:528:DC%2BD1MXoslaksb4%3D
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Gizer IR, Ficks C, Waldman ID. Candidate gene studies of ADHD: a meta-analytic review. Hum Genet. 2009;126(1):51–90.
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(2009)
Hum Genet
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Gizer, I.R.1
Ficks, C.2
Waldman, I.D.3
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14
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79953297780
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Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls
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Shook D, Brady C, Lee PS, Kenealy L, Murphy ER, Gaillard WD, et al. Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls. Am J Med Genet B. 2011;156B(1):28–35.
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Am J Med Genet B
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Shook, D.1
Brady, C.2
Lee, P.S.3
Kenealy, L.4
Murphy, E.R.5
Gaillard, W.D.6
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15
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79956126861
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fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD
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PID: 21232548
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Braet W, Johnson KA, Tobin CT, Acheson R, McDonnell C, Hawi Z, et al. fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD. Neuropsychologia. 2011;49(7):1641–50.
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(2011)
Neuropsychologia
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, pp. 1641-1650
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Braet, W.1
Johnson, K.A.2
Tobin, C.T.3
Acheson, R.4
McDonnell, C.5
Hawi, Z.6
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16
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84857755456
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Attention deficit hyperactivity disorder pharmacogenetics: the dopamine transporter and D4 receptor
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PID: 22379991, COI: 1:CAS:528:DC%2BC38Xjt1ajsr4%3D, This is a review on pharmacogenetics and ADHD focusing on DAT1 and DRD4 genes. The author concludes that there is no evidence at present to suggest any role for pharmacogenetics in the clinical management of ADHD for SLA6A3, DRD4 or any other genetic polymorphism
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McGough JJ. Attention deficit hyperactivity disorder pharmacogenetics: the dopamine transporter and D4 receptor. Pharmacogenomics. 2012;13(4):365–8. This is a review on pharmacogenetics and ADHD focusing on DAT1 and DRD4 genes. The author concludes that there is no evidence at present to suggest any role for pharmacogenetics in the clinical management of ADHD for SLA6A3, DRD4 or any other genetic polymorphism.
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(2012)
Pharmacogenomics
, vol.13
, Issue.4
, pp. 365-368
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McGough, J.J.1
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17
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84901621991
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ADHD pharmacogenetics across the life cycle: new findings and perspectives
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PID: 24804845, This is a systematic review of the literature on ADHD pharmacogenetics to provide a critical discussion of the existent findings, new approaches, limitations, and recommendations for future research. It focuses on the number of studies continues to grow, and the heterogeneity in methodological strategies employed by different studies
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Bruxel EM, Akutagava-Martins GC, Salatino-Oliveira A, Contini V, Kieling C, Hutz MH, et al. ADHD pharmacogenetics across the life cycle: new findings and perspectives. Am J Med Genet B Neuropsychiatr Genet. 2014. doi:10.1002/ajmg.b.32240. This is a systematic review of the literature on ADHD pharmacogenetics to provide a critical discussion of the existent findings, new approaches, limitations, and recommendations for future research. It focuses on the number of studies continues to grow, and the heterogeneity in methodological strategies employed by different studies.
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(2014)
Am J Med Genet B Neuropsychiatr Genet
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Bruxel, E.M.1
Akutagava-Martins, G.C.2
Salatino-Oliveira, A.3
Contini, V.4
Kieling, C.5
Hutz, M.H.6
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18
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37849053744
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Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation
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PID: 18174826
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Durston S, Fossella JA, Mulder MJ, Casey BJ, Ziermans TB, Vessaz MN, et al. Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation. J Am Acad Child Adolesc Psychiatry. 2008;47(1):61–7.
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J Am Acad Child Adolesc Psychiatry
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Durston, S.1
Fossella, J.A.2
Mulder, M.J.3
Casey, B.J.4
Ziermans, T.B.5
Vessaz, M.N.6
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19
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84893646320
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Meta-analysis of the association between dopamine transporter genotype and response to methylphenidate treatment in ADHD
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PID: 23588108, COI: 1:CAS:528:DC%2BC3sXlvVCms7g%3D, This is a a meta-analysis of studies investigating the moderating effect of the SLC6A3 VNTR on response to methylphenidate treatment in subjects with ADHD. The results indicate that SLC6A3 VNTR is not a reliable predictor of methylphenidate treatment success in ADHD
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Kambeitz J, Romanos M, Ettinger U. Meta-analysis of the association between dopamine transporter genotype and response to methylphenidate treatment in ADHD. Pharmacogenomics J. 2014;14(1):77–84. This is a a meta-analysis of studies investigating the moderating effect of the SLC6A3 VNTR on response to methylphenidate treatment in subjects with ADHD. The results indicate that SLC6A3 VNTR is not a reliable predictor of methylphenidate treatment success in ADHD.
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(2014)
Pharmacogenomics J
, vol.14
, Issue.1
, pp. 77-84
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Kambeitz, J.1
Romanos, M.2
Ettinger, U.3
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20
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77956229944
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Dopamine transporter gene variation modulates activation of striatum in youth with ADHD
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PID: 20026227, COI: 1:CAS:528:DC%2BC3cXhtFWqtrvE
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Bedard AC, Schulz KP, Cook EH, Fan J, Clerkin SM, Ivanov I, et al. Dopamine transporter gene variation modulates activation of striatum in youth with ADHD. Neuroimage. 2010;53(3):935–42.
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Neuroimage
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Bedard, A.C.1
Schulz, K.P.2
Cook, E.H.3
Fan, J.4
Clerkin, S.M.5
Ivanov, I.6
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21
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80051553157
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Neuropsychological endophenotypes in attention-deficit/hyperactivity disorder: a review of genetic association studies
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PID: 21409419
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Kebir O, Joober R. Neuropsychological endophenotypes in attention-deficit/hyperactivity disorder: a review of genetic association studies. Eur Arch Psychiatry Clin Neurosci. 2011;261(8):583–94.
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Eur Arch Psychiatry Clin Neurosci
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, pp. 583-594
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Kebir, O.1
Joober, R.2
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22
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79958173109
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The molecular genetics of executive function: role of monoamine system genes
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PID: 21397212, COI: 1:CAS:528:DC%2BC3MXnt1Kksro%3D
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Barnes JJM, Dean AJ, Nandam LS, O’Connell RG, Bellgrove MA. The molecular genetics of executive function: role of monoamine system genes. Biol Psychiatry. 2011;69(12):E127–43.
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(2011)
Biol Psychiatry
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, Issue.12
, pp. E127-E143
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Barnes, J.J.M.1
Dean, A.J.2
Nandam, L.S.3
O’Connell, R.G.4
Bellgrove, M.A.5
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23
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67349196030
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Influence of SLC6A3 and COMT variation on neural activation during response inhibition
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PID: 19482231
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Congdon E, Constable RT, Lesch KP, Canli T. Influence of SLC6A3 and COMT variation on neural activation during response inhibition. Biol Psychol. 2009;81(3):144–52.
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Biol Psychol
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, pp. 144-152
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Congdon, E.1
Constable, R.T.2
Lesch, K.P.3
Canli, T.4
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24
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84858970633
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Striatal dopamine transporter alterations in ADHD: pathophysiology or adaptation to psychostimulants? A meta-analysis
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PID: 22294258
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Fusar-Poli P, Rubia K, Rossi G, Sartori G, Balottin U. Striatal dopamine transporter alterations in ADHD: pathophysiology or adaptation to psychostimulants? A meta-analysis. Am J Psychiatr. 2012;169(3):264–72.
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Am J Psychiatr
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, pp. 264-272
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Fusar-Poli, P.1
Rubia, K.2
Rossi, G.3
Sartori, G.4
Balottin, U.5
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25
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84888390310
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Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls
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PID: 23793356, This review summarizes progress in efforts to incorporate neuroimaging into genetics and treatment research on major psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, attention-deficit/hyperactivity disorder, and addiction
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Falcone M, Smith RM, Chenoweth MJ, Bhattacharjee AK, Kelsoe JR, Tyndale RF, et al. Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls. Neuropsychopharmacology. 2013;38(12):2327–37. This review summarizes progress in efforts to incorporate neuroimaging into genetics and treatment research on major psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, attention-deficit/hyperactivity disorder, and addiction.
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(2013)
Neuropsychopharmacology
, vol.38
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, pp. 2327-2337
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Falcone, M.1
Smith, R.M.2
Chenoweth, M.J.3
Bhattacharjee, A.K.4
Kelsoe, J.R.5
Tyndale, R.F.6
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26
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84862681153
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Striatal sensitivity during reward processing in attention-deficit/hyperactivity disorder
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PID: 22721595
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Paloyelis Y, Mehta MA, Faraone SV, Asherson P, Kuntsi J. Striatal sensitivity during reward processing in attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2012;51(7):722–32.
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J Am Acad Child Adolesc Psychiatry
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Paloyelis, Y.1
Mehta, M.A.2
Faraone, S.V.3
Asherson, P.4
Kuntsi, J.5
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27
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70349662013
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Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorder
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PID: 19805704, COI: 1:CAS:528:DC%2BD1MXhtleiurnO
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Bellgrove MA, Johnson KA, Barry E, Mulligan A, Hawi Z, Gill M, et al. Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatr. 2009;66(10):1135–42.
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Arch Gen Psychiatr
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Bellgrove, M.A.1
Johnson, K.A.2
Barry, E.3
Mulligan, A.4
Hawi, Z.5
Gill, M.6
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28
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84888603131
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Association between the DAT1 gene and spatial working memory in attention deficit hyperactivity disorder
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PID: 24008096, COI: 1:CAS:528:DC%2BC3sXhvVOisbbL
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Shang CY, Gau SSF. Association between the DAT1 gene and spatial working memory in attention deficit hyperactivity disorder. Int J Neuropsychopharmacol. 2014;17(1):9–21.
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Int J Neuropsychopharmacol
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Shang, C.Y.1
Gau, S.S.F.2
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29
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73949090411
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Familiality and molecular genetics of attention networks in ADHD
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PID: 19418498
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Konrad K, Dempfle A, Friedel S, Heiser P, Holtkamp K, Walitza S, et al. Familiality and molecular genetics of attention networks in ADHD. Am J Med Genet B Neuropsychiatr Genet. 2010;153B(1):148–58.
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Am J Med Genet B Neuropsychiatr Genet
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Konrad, K.1
Dempfle, A.2
Friedel, S.3
Heiser, P.4
Holtkamp, K.5
Walitza, S.6
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30
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84867445152
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Role of dopamine receptors in ADHD: a systematic meta-analysis
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PID: 22610946, COI: 1:CAS:528:DC%2BC38XptVWlsL4%3D, This review summarized the ongoing research of DA receptor genes in ADHD pathogenesis and gathered the past published data with meta-analysis and revealed the high risk of DRD5, DRD2, and DRD4 polymorphisms in ADHD
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Wu J, Xiao HF, Sun HJ, Zou L, Zhu LQ. Role of dopamine receptors in ADHD: a systematic meta-analysis. Mol Neurobiol. 2012;45(3):605–20. This review summarized the ongoing research of DA receptor genes in ADHD pathogenesis and gathered the past published data with meta-analysis and revealed the high risk of DRD5, DRD2, and DRD4 polymorphisms in ADHD.
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(2012)
Mol Neurobiol
, vol.45
, Issue.3
, pp. 605-620
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Wu, J.1
Xiao, H.F.2
Sun, H.J.3
Zou, L.4
Zhu, L.Q.5
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31
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80052764999
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Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder
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PID: 21906006
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Taurines R, Grunblatt E, Schecklmann M, Schwenck C, Albantakis L, Reefschlager L, et al. Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder. World J Biol Psychiatry. 2011;12:104–8.
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World J Biol Psychiatry
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Taurines, R.1
Grunblatt, E.2
Schecklmann, M.3
Schwenck, C.4
Albantakis, L.5
Reefschlager, L.6
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32
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37649015910
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Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation
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PID: 18024590, COI: 1:CAS:528:DC%2BD1cXitlKgtw%3D%3D
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Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, et al. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci U S A. 2007;104(49):19649–54.
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Shaw, P.1
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84911001706
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Wu Z, Yang L, Wang Y. Applying Imaging Genetics to ADHD: the Promises and the Challenges. Mol Neurobiol. 2014 Apr 1. This is an exhaustive review on neuroimaging genetics in ADHD. The authors conclude that imaging genetics has somewhat showed its potential to provide a more precise understanding of how the genes shape the brain variations and further the clinical features of ADHD
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Wu Z, Yang L, Wang Y. Applying Imaging Genetics to ADHD: the Promises and the Challenges. Mol Neurobiol. 2014 Apr 1. doi:10.1007/s12035-014-8683-z. This is an exhaustive review on neuroimaging genetics in ADHD. The authors conclude that imaging genetics has somewhat showed its potential to provide a more precise understanding of how the genes shape the brain variations and further the clinical features of ADHD.
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57349087863
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Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations
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COI: 1:CAS:528:DC%2BD1cXhsFWktLrE
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Lasky-Su J, Neale BM, Franke B, Anney RJL, Zhou KX, Maller JB, et al. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B. 2008;147B(8):1345–54.
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Lasky-Su, J.1
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Anney, R.J.L.4
Zhou, K.X.5
Maller, J.B.6
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35
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0032695572
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Association of the dopamine transporter gene (DAT1) with poor methylphenidate response
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PID: 10596245, COI: 1:STN:280:DC%2BD3c%2FmsVSnsA%3D%3D
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Winsberg BG, Comings DE. Association of the dopamine transporter gene (DAT1) with poor methylphenidate response. J Am Acad Child Adolesc Psychiatry. 1999;38(12):1474–7.
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2142711669
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Association of the dopamine D5 receptor with attention deficit hyperactivity disorder (ADHD) and scores on a continuous performance test (TOVA)
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Manor I, Corbex M, Eisenberg J, Gritsenkso I, Bachner-Melman R, Tyano S, et al. Association of the dopamine D5 receptor with attention deficit hyperactivity disorder (ADHD) and scores on a continuous performance test (TOVA). Am J Med Genet B. 2004;127B(1):73–7.
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Tyano, S.6
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37
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74949113916
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Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics
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PID: 20088618, COI: 1:CAS:528:DC%2BC3cXktlSrtb4%3D
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Froehlich TE, McGough JJ, Stein MA. Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics. CNS Drugs. 2010;24(2):99–117.
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CNS Drugs
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Froehlich, T.E.1
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Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes
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PID: 18665883
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Loo SK, Rich EC, Ishii J, McGough J, McCracken J, Nelson S, et al. Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes. J Child Psychol Psychiatry. 2008;49(9):950–7.
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J Child Psychol Psychiatry
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Loo, S.K.1
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39
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84867002677
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PID: 23021477, This is an exhaustive meta-analysis providing evidence for several peripheral biomarkers as being associated with ADHD both in diagnosis and in treatment efficacy
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Scassellati C, Bonvicini C, Faraone SV, Gennarelli M. Biomarkers and attention-deficit/hyperactivity disorder: a systematic review and meta-analyses. J Am Acad Child Adolesc Psychiatry. 2012;51(10):1003–19. This is an exhaustive meta-analysis providing evidence for several peripheral biomarkers as being associated with ADHD both in diagnosis and in treatment efficacy.
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40
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84862809641
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Regional brain perfusion before and after treatment with methylphenidate may be associated with the G1287A polymorphism of the norepinephrine transporter gene in children with attention-deficit/hyperactivity disorder
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PID: 22405810, COI: 1:CAS:528:DC%2BC38XkvFWhsL4%3D
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Park MH, Kim JW, Yang YH, Hong SB, Park S, Kang H, et al. Regional brain perfusion before and after treatment with methylphenidate may be associated with the G1287A polymorphism of the norepinephrine transporter gene in children with attention-deficit/hyperactivity disorder. Neurosci Lett. 2012;514(2):159–63.
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41
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84877585551
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Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder
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PID: 23609393, COI: 1:CAS:528:DC%2BC3sXmvFOht7c%3D
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Kim BN, Kim JW, Cummins TDR, Bellgrove MA, Hawi Z, Hong SB, et al. Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder. J Clin Psychopharmacol. 2013;33(3):356–62.
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42
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Lerch, J.P.5
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43
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57349101889
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SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families
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COI: 1:CAS:528:DC%2BD1cXhsFWktLnF
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Kollins SH, Anastopoulos AD, Lachiewicz AM, FitzGerald D, Morrissey-Kane E, Garrett ME, et al. SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. Am J Med Genet B. 2008;147B(8):1580–8.
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44
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79955470881
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Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree
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PID: 20308990, COI: 1:CAS:528:DC%2BC3MXltVGlu7o%3D
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Lesch KP, Selch S, Renner TJ, Jacob C, Nguyen TT, Hahn T, et al. Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree. Mol Psychiatry. 2011;16(5):491–503.
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Lesch, K.P.1
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Hahn, T.6
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45
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84879891336
-
No association between MspI allele of the ADRA2A polymorphism and ADHD: meta-analysis of family-based studies
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PID: 23751900, COI: 1:CAS:528:DC%2BC3sXhtVegu7rK
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Shiffrin ND, Gruber J, Glatt SJ, Faraone SV. No association between MspI allele of the ADRA2A polymorphism and ADHD: meta-analysis of family-based studies. Psychiatr Genet. 2013;23(4):174–5.
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Shiffrin, N.D.1
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46
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80054862518
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Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder
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PID: 22024001
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Froehlich TE, Epstein JN, Nick TG, Castro MSM, Stein MA, Brinkman WB, et al. Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2011;50(11):1129–39.
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Froehlich, T.E.1
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Nick, T.G.3
Castro, M.S.M.4
Stein, M.A.5
Brinkman, W.B.6
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47
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84879555010
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Adrenergic neurotransmitter system transporter and receptor genes associated with atomoxetine response in attention-deficit hyperactivity disorder children
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PID: 23266789, COI: 1:CAS:528:DC%2BC3sXhtVSmtrrL
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Yang L, Qian Q, Liu L, Li H, Faraone SV, Wang Y. Adrenergic neurotransmitter system transporter and receptor genes associated with atomoxetine response in attention-deficit hyperactivity disorder children. J Neural Transm. 2013;120(7):1127–33.
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J Neural Transm
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Yang, L.1
Qian, Q.2
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Wang, Y.6
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48
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84894320904
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Role of COMT in ADHD: a systematic meta-analysis
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PID: 23907791, COI: 1:CAS:528:DC%2BC3sXht1Shs7zI, This is a meta-analysis on findings investigating associations between COMT gene and ADHD. The results indicated no association
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Sun HJ, Yuan FF, Shen XM, Xiong GL, Wu J. Role of COMT in ADHD: a systematic meta-analysis. Mol Neurobiol. 2014;49(1):251–61. This is a meta-analysis on findings investigating associations between COMT gene and ADHD. The results indicated no association.
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Mol Neurobiol
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, pp. 251-261
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Sun, H.J.1
Yuan, F.F.2
Shen, X.M.3
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Wu, J.5
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49
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77953293611
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Gene-gene interaction between COMT and MAOA potentially predicts the intelligence of attention-deficit hyperactivity disorder boys in China
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PID: 19941049
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Qian QJ, Yang L, Wang YF, Zhang HB, Guan LL, Chen Y, et al. Gene-gene interaction between COMT and MAOA potentially predicts the intelligence of attention-deficit hyperactivity disorder boys in China. Behav Genet. 2010;40(3):357–65.
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Qian, Q.J.1
Yang, L.2
Wang, Y.F.3
Zhang, H.B.4
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Chen, Y.6
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50
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27744534613
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Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder
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PID: 16275815, COI: 1:CAS:528:DC%2BD2MXht1CgsLzF
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Thapar A, Langley K, Fowler T, Rice F, Turic D, Whittinger N, et al. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatr. 2005;62(11):1275–8.
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Fowler, T.3
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Whittinger, N.6
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51
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38949113693
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A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder
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PID: 18250258
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Caspi A, Langley K, Milne B, Moffitt TE, O’Donovan M, Owen MJ, et al. A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatr. 2008;65(2):203–10.
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Caspi, A.1
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Milne, B.3
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Owen, M.J.6
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52
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54449086933
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Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder
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PID: 18703939
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Cheon KA, Jun JY, Cho DY. Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder. Int Clin Psychopharmacol. 2008;23(5):291–8.
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Cheon, K.A.1
Jun, J.Y.2
Cho, D.Y.3
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53
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57349196728
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Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children
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COI: 1:CAS:528:DC%2BD1cXhsFWktLvL
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Kereszturi E, Tarnok Z, Bognar E, Lakatos K, Farkas L, Gadoros J, et al. Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. Am J Med Genet B. 2008;147B(8):1431–5.
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Am J Med Genet B
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Kereszturi, E.1
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Lakatos, K.4
Farkas, L.5
Gadoros, J.6
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54
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0036024267
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Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA)
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PID: 12140786, COI: 1:CAS:528:DC%2BD38XlsFWrsbs%3D
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Manor I, Tyano S, Mel E, Eisenberg J, Bachner-Melman R, Kotler M, et al. Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA). Mol Psychiatry. 2002;7(6):626–32.
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(2002)
Mol Psychiatry
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Manor, I.1
Tyano, S.2
Mel, E.3
Eisenberg, J.4
Bachner-Melman, R.5
Kotler, M.6
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55
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57349124043
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Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls
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COI: 1:CAS:528:DC%2BD1cXhsFWktLnN
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Rommelse NNJ, Altink ME, Arias-Vasquez A, Buschgens CJM, Fliers E, Faraone SV, et al. Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls. Am J Med Genet B. 2008;147B(8):1524–30.
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Am J Med Genet B
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Rommelse, N.N.J.1
Altink, M.E.2
Arias-Vasquez, A.3
Buschgens, C.J.M.4
Fliers, E.5
Faraone, S.V.6
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56
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84884670740
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Neural mechanisms of attention-deficit/hyperactivity disorder symptoms are stratified by MAOA genotype
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PID: 23746540, COI: 1:CAS:528:DC%2BC3sXptFGmur0%3D
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Nymberg C, Jia T, Lubbe S, Ruggeri B, Desrivieres S, Barker G, et al. Neural mechanisms of attention-deficit/hyperactivity disorder symptoms are stratified by MAOA genotype. Biol Psychiatry. 2013;74(8):607–14.
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Nymberg, C.1
Jia, T.2
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Desrivieres, S.5
Barker, G.6
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57
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45149118397
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The -1021 C/T DBH polymorphism is associated with neuropsychological performance among children and adolescents with ADHD
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PID: 18081028
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Kieling C, Genro JP, Hutz MH, Rohde LA. The -1021 C/T DBH polymorphism is associated with neuropsychological performance among children and adolescents with ADHD. Am J Med Genet B Neuropsychiatr Genet. 2008;147B(4):485–90.
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Am J Med Genet B Neuropsychiatr Genet
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Kieling, C.1
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Rohde, L.A.4
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58
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56449115578
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Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children with attention deficit-hyperactivity disorder (ADHD)
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COI: 1:CAS:528:DC%2BD1cXhsVerurbM
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Shim SH, Hwangbo Y, Kwon YJ, Jeong HY, Lee BH, Lee HJ, et al. Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children with attention deficit-hyperactivity disorder (ADHD). Prog Neuro-Psychopharmacol Biol Psychiatry. 2008;32(8):1824–8.
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Prog Neuro-Psychopharmacol Biol Psychiatry
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Shim, S.H.1
Hwangbo, Y.2
Kwon, Y.J.3
Jeong, H.Y.4
Lee, B.H.5
Lee, H.J.6
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59
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80053439047
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Treadmill exercise and methylphenidate ameliorate symptoms of attention deficit/hyperactivity disorder through enhancing dopamine synthesis and brain-derived neurotrophic factor expression in spontaneous hypertensive rats
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PID: 21907264, COI: 1:CAS:528:DC%2BC3MXht1Ght7rF
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Kim H, Heo HI, Kim DH, Ko IG, Lee SS, Kim SE, et al. Treadmill exercise and methylphenidate ameliorate symptoms of attention deficit/hyperactivity disorder through enhancing dopamine synthesis and brain-derived neurotrophic factor expression in spontaneous hypertensive rats. Neurosci Lett. 2011;504(1):35–9.
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Kim, H.1
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Kim, S.E.6
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60
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84897097537
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Serum brain-derived neurotrophic factor (BDNF) levels in attention deficit-hyperactivity disorder (ADHD)
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Scassellati C, Zanardini R, Tiberti A, Pezzani M, Valenti V, Effedri P, et al. Serum brain-derived neurotrophic factor (BDNF) levels in attention deficit-hyperactivity disorder (ADHD). Eur Child Adolesc Psichiatry. 2014;23(3):173–7.
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Eur Child Adolesc Psichiatry
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Zanardini, R.2
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Effedri, P.6
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61
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84943552155
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Joseph N, Zhang-James Y, Perl A, Faraone SV. Oxidative Stress and ADHD: A Meta-Analysis. J Atten Disord. 2013;20(10):1–10. The authors performed a meta-analysis of studies on oxidative stress and antioxidant status in medication naive patients with ADHD and controls. The results suggest that patients with ADHD have normal levels of antioxidant production, but that their response to oxidative stress is insufficient, leading to oxidative damage
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Joseph N, Zhang-James Y, Perl A, Faraone SV. Oxidative Stress and ADHD: A Meta-Analysis. J Atten Disord. 2013;20(10):1–10 doi:10.1177/1087054713510354. The authors performed a meta-analysis of studies on oxidative stress and antioxidant status in medication naive patients with ADHD and controls. The results suggest that patients with ADHD have normal levels of antioxidant production, but that their response to oxidative stress is insufficient, leading to oxidative damage.
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62
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84878444524
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A decade of EEG theta/beta ratio research in ADHD: a meta-analysis
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PID: 23086616, This is a meta-analysis on the TBR in ADHD. The results indicated that excessive TBR cannot be considered a reliable diagnostic measure of ADHD, however a substantial sub-group of ADHD patients do deviate on this measure and TBR has prognostic value in this sub-group, warranting its use as a prognostic measure rather than a diagnostic measure
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Arns M, Conners CK, Kraemer HC. A decade of EEG theta/beta ratio research in ADHD: a meta-analysis. J Atten Disord. 2013;17(5):374–83. This is a meta-analysis on the TBR in ADHD. The results indicated that excessive TBR cannot be considered a reliable diagnostic measure of ADHD, however a substantial sub-group of ADHD patients do deviate on this measure and TBR has prognostic value in this sub-group, warranting its use as a prognostic measure rather than a diagnostic measure.
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J Atten Disord
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Arns, M.1
Conners, C.K.2
Kraemer, H.C.3
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63
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84876981063
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Brain oscillations as biomarkers in neuropsychiatric disorders: following an interactive panel discussion and synopsis
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PID: 24053048
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Yener GG, Basar E. Brain oscillations as biomarkers in neuropsychiatric disorders: following an interactive panel discussion and synopsis. Suppl Clin Neurophysiol. 2013;62:343–63.
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Suppl Clin Neurophysiol
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Yener, G.G.1
Basar, E.2
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64
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3242681428
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Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder
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PID: 15291732
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Frazier TW, Demaree HA, Youngstrom EA. Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder. Neuropsychology. 2004;18(3):543–55.
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65
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A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder
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PID: 15782085
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Martinussen R, Hayden J, Hogg-Johnson S, Tannock R. A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2005;44(4):377–84.
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Martinussen, R.1
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66
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20444385442
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Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review
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PID: 15950006
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Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF. Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry. 2005;57(11):1336–46.
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Willcutt, E.G.1
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67
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84865080120
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Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): A meta-analytic review
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PID: 22917740
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Kasper LJ, Alderson RM, Hudec KL. Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): A meta-analytic review. Clin Psychol Rev. 2012;32(7):605–17.
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68
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84896462168
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Visuospatial working memory in ADHD patients, unaffected siblings, and healthy controls
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PID: 23569155
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van Ewijk H, Heslenfeld DJ, Luman M, Rommelse NN, Hartman CA, Hoekstra P, et al. Visuospatial working memory in ADHD patients, unaffected siblings, and healthy controls. J Atten Disord. 2014;18(4):369–78.
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The neurobiology and genetics of attention-deficit/hyperactivity disorder (ADHD): what every clinician should know
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Cortese S. The neurobiology and genetics of attention-deficit/hyperactivity disorder (ADHD): what every clinician should know. Eur J Paediatr Neurol. 2012;16(5):422–33.
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Association and linkage of allelic variants of the dopamine transporter gene in ADHD
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PID: 17579611, COI: 1:CAS:528:DC%2BD2sXhtVyjtrrE
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Friedel S, Saar K, Sauer S, Dempfle A, Walitza S, Renner T, et al. Association and linkage of allelic variants of the dopamine transporter gene in ADHD. Mol Psychiatry. 2007;12(10):923–33.
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71
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The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate
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PID: 15572278, COI: 1:CAS:528:DC%2BD2cXhtVantb%2FN
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Cheon KA, Ryu YH, Kim JW, Cho DY. The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate. Eur Neuropsychopharmacol. 2005;15(1):95–101.
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The genetics of attention deficit/hyperactivity disorder in adults, a review
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PID: 22105624, COI: 1:CAS:528:DC%2BC38Xhtl2hsrnO
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Franke B, Faraone SV, Asherson P, Buitelaar J, Bau CHD, Ramos-Quiroga JA, et al. The genetics of attention deficit/hyperactivity disorder in adults, a review. Mol Psychiatry. 2012;17(10):960–87.
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