메뉴 건너뛰기




Volumn 50, Issue 11, 2011, Pages 1129-1139.e2

Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder

Author keywords

attention deficit hyperactivity disorder; dopamine transporter; methylphenidate; pharmacogenetics

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR; DOPAMINE TRANSPORTER; METHYLPHENIDATE; PLACEBO;

EID: 80054862518     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1016/j.jaac.2011.08.002     Document Type: Article
Times cited : (77)

References (76)
  • 1
    • 3042622074 scopus 로고    scopus 로고
    • Clinical practice guideline: Treatment of the school-aged child with attention-deficit/hyperactivity disorder
    • Clinical practice guideline: treatment of the school-aged child with attention-deficit/hyperactivity disorder. Pediatrics. 2001; 108:1033-1044.
    • (2001) Pediatrics , vol.108 , pp. 1033-1044
  • 3
    • 1642320695 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in the treatment of attention-deficit hyperactivity disorder with methylphenidate
    • DOI 10.2165/00023210-200418040-00004
    • Wolraich ML, Doffing MA. Pharmacokinetic considerations in the treatment of attention-deficit hyperactivity disorder with methylphenidate. CNS Drugs. 2004;18:243-250. (Pubitemid 38393434)
    • (2004) CNS Drugs , vol.18 , Issue.4 , pp. 243-250
    • Wolraich, M.L.1    Doffing, M.A.2
  • 4
    • 0021810848 scopus 로고
    • Methylphenidate in hyperactive children: Differential effects of dose on academic, learning, and social behavior
    • DOI 10.1007/BF00910644
    • Rapport MD, Stoner G, DuPaul GJ, Birmingham BK, Tucker S. Methylphenidate in hyperactive children: differential effects of dose on academic, learning, and social behavior. J Abnorm Child Psychol. 1985;13:227-243. (Pubitemid 15053683)
    • (1985) Journal of Abnormal Child Psychology , vol.13 , Issue.2 , pp. 227-243
    • Rapport, M.D.1    Stoner, G.2    DuPaul, G.J.3
  • 5
    • 33748674646 scopus 로고    scopus 로고
    • An overview of the pharmacogenetics and molecular genetics of ADHD
    • DOI 10.2174/157016006778195106
    • Lowe N, Barry E, Gill M, Hawi Z. An overview of the pharmacogenetics and molecular genetics of ADHD. Curr Pharmacogenomics. 2006;4:231-243. (Pubitemid 44383179)
    • (2006) Current Pharmacogenomics , vol.4 , Issue.3 , pp. 231-243
    • Lowe, N.1    Barry, E.2    Gill, M.3    Hawi, Z.4
  • 6
    • 18044384405 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder: Advancing on pharmacogenomics
    • DOI 10.1517/14622416.6.3.225
    • Polanczyk G, Zeni C, Genro JP, Roman T, Hutz MH, Rohde LA. Attention-deficit/hyperactivity disorder: advancing on pharmacogenomics. Pharmacogenomics. 2005;6:225-234. (Pubitemid 40601626)
    • (2005) Pharmacogenomics , vol.6 , Issue.3 , pp. 225-234
    • Polanczyk, G.1    Zeni, C.2    Genro, J.P.3    Roman, T.4    Hutz, M.H.5    Rohde, L.A.6
  • 7
    • 20444430422 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder pharmacogenomics
    • DOI 10.1016/j.biopsych.2004.10.021, PII S0006322304011011
    • McGough JJ. Attention-deficit/hyperactivity disorder pharmacogenomics. Biol Psychiatry. 2005;57:1367-1373. (Pubitemid 40798556)
    • (2005) Biological Psychiatry , vol.57 , Issue.11 , pp. 1367-1373
    • McGough, J.J.1
  • 8
    • 74949113916 scopus 로고    scopus 로고
    • Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics
    • Froehlich TE, McGough JJ, Stein MA. Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics. CNS Drugs. 2010;24:99-117.
    • (2010) CNS Drugs , vol.24 , pp. 99-117
    • Froehlich, T.E.1    McGough, J.J.2    Stein, M.A.3
  • 9
    • 39449094563 scopus 로고    scopus 로고
    • The Pharmacogenomic Era: Promise for Personalizing Attention Deficit Hyperactivity Disorder Therapy
    • DOI 10.1016/j.chc.2007.11.009, PII S105649930700123X
    • Stein MA, McGough JJ. The pharmacogenomic era: promise for personalizing attention deficit hyperactivity disorder therapy. Child Adolesc Psychiatr Clin North Am. 2008;17:475-490, xi-xii. (Pubitemid 351265399)
    • (2008) Child and Adolescent Psychiatric Clinics of North America , vol.17 , Issue.2 , pp. 475-490
    • Stein, M.A.1    McGough, J.J.2
  • 10
    • 27844473803 scopus 로고    scopus 로고
    • Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder
    • DOI 10.1038/sj.npp.1300839, PII 1300839
    • Bellgrove MA, Hawi Z, Kirley A, Fitzgerald M, Gill M, Robertson IH. Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder. Neuropsychopharmacology. 2005;30:2290-2297. (Pubitemid 41643982)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.12 , pp. 2290-2297
    • Bellgrove, M.A.1    Hawi, Z.2    Kirley, A.3    Fitzgerald, M.4    Gill, M.5    Robertson, I.H.6
  • 11
    • 1642293724 scopus 로고    scopus 로고
    • Mechanism of action of methylphenidate: Insights from PET imaging studies
    • Volkow ND, Fowler JS, Wang G, Ding Y, Gatley SJ. Mechanism of action of methylphenidate: insights from PET imaging studies. J Atten Disord. 2002;6(suppl 1):S31-S43.
    • (2002) J Atten Disord , vol.6 , Issue.SUPPL. 1
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.3    Ding, Y.4    Gatley, S.J.5
  • 12
    • 2342444355 scopus 로고    scopus 로고
    • Polymorphisms of the Dopamine Transporter Gene: Influence on Response to Methylphenidate in Attention Deficit-Hyperactivity Disorder
    • DOI 10.2165/00129785-200404020-00003
    • Roman T, Rohde LA, Hutz MH. Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit- hyperactivity disorder. Am J Pharmacogenomics. 2004;4:83-92. (Pubitemid 38560315)
    • (2004) American Journal of PharmacoGenomics , vol.4 , Issue.2 , pp. 83-92
    • Roman, T.1    Rohde, L.A.2    Hutz, M.H.3
  • 13
    • 0032695572 scopus 로고    scopus 로고
    • Association of the dopamine transporter gene (DAT1) with poor methylphenidate response
    • Winsberg BG, Comings DE. Association of the dopamine transporter gene (DAT1) with poor methylphenidate response. J Am Acad Child Adolesc Psychiatry. 1999;38:1474-1477.
    • (1999) J Am Acad Child Adolesc Psychiatry , vol.38 , pp. 1474-1477
    • Winsberg, B.G.1    Comings, D.E.2
  • 14
    • 0036667960 scopus 로고    scopus 로고
    • Dopamine transporter gene and response to methylphenidate in attention-deficit/hyperactivity disorder
    • DOI 10.1097/00008571-200208000-00011
    • Roman T, Szobot C, Martins S, Biederman J, Rohde LA, Hutz MH. Dopamine transporter gene and response to methylphenidate in attention-deficit/ hyperactivity disorder. Pharmacogenetics. 2002; 12:497-499. (Pubitemid 34913533)
    • (2002) Pharmacogenetics , vol.12 , Issue.6 , pp. 497-499
    • Roman, T.1    Szobot, C.2    Martins, S.3    Biederman, J.4    Rohde, L.A.5    Hutz, M.H.6
  • 15
    • 9644254417 scopus 로고    scopus 로고
    • The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: Relating to treatment response to methylphenidate
    • Cheon KA, Ryu YH, Kim JW, Cho DY. The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate. Eur Neuropsychopharmacol. 2005;15:95-101.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 95-101
    • Cheon, K.A.1    Ryu, Y.H.2    Kim, J.W.3    Cho, D.Y.4
  • 16
    • 57349153231 scopus 로고    scopus 로고
    • Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: Association with the dopamine transporter gene (SLC6A3)
    • Purper-Ouakil D, Wohl M, Orejarena S, et al. Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: association with the dopamine transporter gene (SLC6A3). Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1425-1430.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1425-1430
    • Purper-Ouakil, D.1    Wohl, M.2    Orejarena, S.3
  • 20
    • 71649097398 scopus 로고    scopus 로고
    • A candidate gene analysis of methylphenidate response in attention-deficit/hyper-activity disorder
    • McGough JJ, McCracken JT, Loo SK, et al. A candidate gene analysis of methylphenidate response in attention-deficit/hyper-activity disorder. J Am Acad Child Adolesc Psychiatry. 2009;48: 1155-1164.
    • (2009) J Am Acad Child Adolesc Psychiatry , vol.48 , pp. 1155-1164
    • McGough, J.J.1    McCracken, J.T.2    Loo, S.K.3
  • 23
    • 49549116451 scopus 로고    scopus 로고
    • Spatial attentional bias as a marker of genetic risk, symptom severity, and stimulant response in ADHD
    • Bellgrove MA, Barry E, Johnson KA, et al. Spatial attentional bias as a marker of genetic risk, symptom severity, and stimulant response in ADHD. Neuropsychopharmacology. 2008;33:2536-2545.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2536-2545
    • Bellgrove, M.A.1    Barry, E.2    Johnson, K.A.3
  • 24
  • 25
    • 57349196728 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children
    • Kereszturi E, Tarnok Z, Bognar E, et al. Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1431-1435.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1431-1435
    • Kereszturi, E.1    Tarnok, Z.2    Bognar, E.3
  • 27
    • 74949111159 scopus 로고    scopus 로고
    • Synaptic function and biochemical neuroanatomy
    • Martin A, Scahill L, Charney DS, Leckman JF, eds New York: Oxford University Press
    • Heckers S, Konradi C. Synaptic function and biochemical neuroanatomy. In: Martin A, Scahill L, Charney DS, Leckman JF, eds. Pediatric Psychopharmacology: Principles and Practice. New York: Oxford University Press; 2003:20-32.
    • (2003) Pediatric Psychopharmacology: Principles and Practice , pp. 20-32
    • Heckers, S.1    Konradi, C.2
  • 29
    • 0035798254 scopus 로고    scopus 로고
    • Marker gene polymorphisms in hyperkinetic disorder - Predictors of clinical response to treatment with methylphenidate?
    • DOI 10.1016/S0304-3940(01)02253-4, PII S0304394001022534
    • Seeger G, Schloss P, Schmidt MH. Marker gene polymorphisms in hyperkinetic disorder-predictors of clinical response to treatment with methylphenidate? Neurosci Lett. 2001;313:45-48. (Pubitemid 32973891)
    • (2001) Neuroscience Letters , vol.313 , Issue.1-2 , pp. 45-48
    • Seeger, G.1    Schloss, P.2    Schmidt, M.H.3
  • 30
    • 12744273099 scopus 로고    scopus 로고
    • Dopamine receptor 4 (DRD4) 7-repeat allele predicts methylphenidate dose response in children with attention deficit hyper-activity disorder: A pharmacogenetic study
    • Hamarman S, Fossella J, Ulger C, Brimacombe M, Dermody J. Dopamine receptor 4 (DRD4) 7-repeat allele predicts methylphenidate dose response in children with attention deficit hyper-activity disorder: a pharmacogenetic study. J Child Adolesc Psychopharmacol. 2004;14:564-574.
    • (2004) J Child Adolesc Psychopharmacol , vol.14 , pp. 564-574
    • Hamarman, S.1    Fossella, J.2    Ulger, C.3    Brimacombe, M.4    Dermody, J.5
  • 31
    • 0033923995 scopus 로고    scopus 로고
    • Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children
    • Tahir E, Yazgan Y, Cirakoglu B, Ozbay F, Waldman I, Asherson PJ. Association and linkage of DRD4 and DRD5 with attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children. Mol Psychiatry. 2000;5:396-404. (Pubitemid 30455953)
    • (2000) Molecular Psychiatry , vol.5 , Issue.4 , pp. 396-404
    • Tahir, E.1    Yazgan, Y.2    Cirakoglu, B.3    Ozbay, F.4    Waldman, I.5    Asherson, P.J.6
  • 33
    • 34249009649 scopus 로고    scopus 로고
    • Association of 4-repeat allele of the dopamine D4 receptor gene exon III polymorphism and response to methylphenidate treatment in Korean ADHD children
    • Cheon KA, Kim BN, Cho SC. Association of 4-repeat allele of the dopamine D4 receptor gene exon III polymorphism and response to methylphenidate treatment in Korean ADHD children. Neuropsychopharmacology. 2007;32:1377-1383.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1377-1383
    • Cheon, K.A.1    Kim, B.N.2    Cho, S.C.3
  • 35
    • 0030932778 scopus 로고    scopus 로고
    • MspI identifies a biallelic polymorphism in the promoter region of the alpha(2A)-adrenergic receptor gene
    • Lario S, Calls J, Cases A, Oriola J, Torras A, Rivera F. MspI identifies a biallelic polymorphism in the promoter region of the alpha 2A-adrenergic receptor gene. Clin Genet. 1997;51: 129-130. (Pubitemid 27149724)
    • (1997) Clinical Genetics , vol.51 , Issue.2 , pp. 129-130
    • Lario, S.1    Calls, J.2    Cases, A.3    Oriola, J.4    Torras, A.5    Rivera, F.6
  • 36
    • 33846881796 scopus 로고    scopus 로고
    • Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyperactivity disorder
    • Polanczyk G, Zeni C, Genro JP, et al. Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2007;64:218- 224.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 218-224
    • Polanczyk, G.1    Zeni, C.2    Genro, J.P.3
  • 37
    • 39549085981 scopus 로고    scopus 로고
    • Adrenergic alpha2A receptor gene and response to methylphenidate in attention-deficit/hyperactivity disorder-predominantly inattentive type
    • da Silva TL, Pianca TG, Roman T, et al. Adrenergic alpha2A receptor gene and response to methylphenidate in attention-deficit/hyperactivity disorder-predominantly inattentive type. J Neural Transm. 2008;115:341-345.
    • (2008) J Neural Transm , vol.115 , pp. 341-345
    • Da Silva, T.L.1    Pianca, T.G.2    Roman, T.3
  • 38
    • 61549118495 scopus 로고    scopus 로고
    • Association between homozygosity of a G allele of the alpha-2a-adrenergic receptor gene and methylphenidate response in Korean children and adolescents with attention-deficit/hyper-activity disorder
    • Cheon KA, Cho DY, Koo MS, Song DH, Namkoong K. Association between homozygosity of a G allele of the alpha-2a-adrenergic receptor gene and methylphenidate response in Korean children and adolescents with attention-deficit/hyper-activity disorder. Biol Psychiatry. 2009;65:564-570.
    • (2009) Biol Psychiatry , vol.65 , pp. 564-570
    • Cheon, K.A.1    Cho, D.Y.2    Koo, M.S.3    Song, D.H.4    Namkoong, K.5
  • 39
    • 0030004521 scopus 로고    scopus 로고
    • Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders
    • DOI 10.1097/00008571-199606000-00007
    • Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics. 1996;6:243-250. (Pubitemid 26226317)
    • (1996) Pharmacogenetics , vol.6 , Issue.3 , pp. 243-250
    • Lachman, H.M.1    Papolos, D.F.2    Saito, T.3    Yu, Y.-M.4    Szumlanski, C.L.5    Weinshilboum, R.M.6
  • 40
    • 54449086933 scopus 로고    scopus 로고
    • Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder
    • Cheon KA, Jun JY, Cho DY. Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder. Int Clin Psychopharmacol. 2008;23:291-298.
    • (2008) Int Clin Psychopharmacol , vol.23 , pp. 291-298
    • Cheon, K.A.1    Jun, J.Y.2    Cho, D.Y.3
  • 41
    • 57349085226 scopus 로고    scopus 로고
    • The impact of individual and methodological factors in the variability of response to methylphenidate in ADHD pharmacogenetic studies from four different continents
    • Polanczyk G, Faraone SV, Bau CH, et al. The impact of individual and methodological factors in the variability of response to methylphenidate in ADHD pharmacogenetic studies from four different continents. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1419-1424.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1419-1424
    • Polanczyk, G.1    Faraone, S.V.2    Bau, C.H.3
  • 43
    • 80054872433 scopus 로고    scopus 로고
    • Pharmacogenomics of ADHD
    • Schwab M, Kaschka W, Spina E, eds. Basel: Karger Medical and Scientific Publishers
    • Froehlich TE, Stein MA. Pharmacogenomics of ADHD. In: Schwab M, Kaschka W, Spina E, eds. Pharmacogenomics in Psychiatry. Basel: Karger Medical and Scientific Publishers; 2010.
    • (2010) Pharmacogenomics in Psychiatry
    • Froehlich, T.E.1    Stein, M.A.2
  • 45
    • 0032753828 scopus 로고    scopus 로고
    • A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder
    • The MTA Cooperative Group
    • The MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 1999;56:1073-1086.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 1073-1086
  • 46
    • 0033959254 scopus 로고    scopus 로고
    • NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC- IV): Description, differences from previous versions, and reliability of some common diagnoses
    • Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry. 2000;39:28-38. (Pubitemid 30029897)
    • (2000) Journal of the American Academy of Child and Adolescent Psychiatry , vol.39 , Issue.1 , pp. 28-38
    • Shaffer, D.1    Fisher, P.2    Lucas, C.P.3    Dulcan, M.K.4    Schwab-Stone, M.E.5
  • 48
    • 0344925137 scopus 로고    scopus 로고
    • Psychometric Properties of the Vanderbilt ADHD Diagnostic Parent Rating Scale in a Referred Population
    • DOI 10.1093/jpepsy/jsg046
    • Wolraich ML, Lambert W, Doffing MA, Bickman L, Simmons T, Worley K. Psychometric properties of the Vanderbilt ADHD diagnostic parent rating scale in a referred population. J Pediatr Psychol. 2003;28:559-567. (Pubitemid 37449138)
    • (2003) Journal of Pediatric Psychology , vol.28 , Issue.8 , pp. 559-567
    • Wolraich, M.L.1    Lambert, W.2    Doffing, M.A.3    Bickman, L.4    Simmons, T.5    Worley, K.6
  • 50
    • 44049090677 scopus 로고    scopus 로고
    • Impact of parent and teacher concordance on diagnosing attention deficit hyperactivity disorder and its sub-types
    • DOI 10.1007/s12098-008-0049-y
    • Malhi P, Singhi P, Sidhu M. Impact of parent and teacher concordance on diagnosing attention deficit hyperactivity disorder and its sub-types. Indian J Pediatr. 2008;75:223-228. (Pubitemid 351712985)
    • (2008) Indian Journal of Pediatrics , vol.75 , Issue.3 , pp. 223-228
    • Malhi, P.1    Singhi, P.2    Sidhu, M.3
  • 52
    • 19244370172 scopus 로고    scopus 로고
    • A dose-response study of OROS methylphenidate in children with attention-deficit/hyperactivity disorder
    • Stein MA, Sarampote CS, Waldman ID, et al. A dose-response study of OROS methylphenidate in children with attention-deficit/hyperactivity disorder. Pediatrics. 2003;112:e404.
    • (2003) Pediatrics , vol.112
    • Stein, M.A.1    Sarampote, C.S.2    Waldman, I.D.3
  • 53
    • 0025980497 scopus 로고
    • Attention deficit disorder with and without hyperactivity: Clinical response to three dose levels of methylphenidate
    • Barkley RA, DuPaul GJ, McMurray MB. Attention deficit disorder with and without hyperactivity: clinical response to three dose levels of methylphenidate. Pediatrics. 1991;87:519-531.
    • (1991) Pediatrics , vol.87 , pp. 519-531
    • Barkley, R.A.1    DuPaul, G.J.2    McMurray, M.B.3
  • 55
    • 0000913564 scopus 로고
    • Further comparative analyses of prettest-posttest research designs
    • Laird N. Further comparative analyses of prettest-posttest research designs. Am Stat. 1983;37:329-330.
    • (1983) Am Stat , vol.37 , pp. 329-330
    • Laird, N.1
  • 56
    • 0017035801 scopus 로고
    • Predicting the response of hyperkinetic children to stimulant drugs: A review
    • DOI 10.1007/BF00922531
    • Barkley RA. Predicting the response of hyperkinetic children to stimulant drugs: a review. J Abnorm Child Psychol. 1976;4:327-348. (Pubitemid 8019377)
    • (1976) Journal of Abnormal Child Psychology , vol.4 , Issue.4 , pp. 327-348
    • Barkley, R.A.1
  • 58
    • 26444448415 scopus 로고    scopus 로고
    • Multicenter, randomized, open-label study of OROS methylphenidate versus atomoxetine: Treatment outcomes in African-American children with ADHD
    • Starr HL, Kemner J. Multicenter, randomized, open-label study of OROS methylphenidate versus atomoxetine: treatment outcomes in African-American children with ADHD. J Natl Med Assoc. 2005;97(suppl):11S-16S. (Pubitemid 41429050)
    • (2005) Journal of the National Medical Association , vol.97 , Issue.10 SUPPL.
    • Starr, H.L.1    Kemner, J.2
  • 61
    • 0347287028 scopus 로고    scopus 로고
    • The human dopamine D4 receptor repeat sequences modulate expression
    • DOI 10.1038/sj.tpj.6500208
    • Schoots O, Van Tol HH. The human dopamine D4 receptor repeat sequences modulate expression. Pharmacogenomics J. 2003;3:343-348. (Pubitemid 38072172)
    • (2003) Pharmacogenomics Journal , vol.3 , Issue.6 , pp. 343-348
    • Schoots, O.1    Van Tol, H.H.M.2
  • 62
    • 0029120447 scopus 로고
    • Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants
    • Asghari V, Sanyal S, Buchwaldt S, Paterson A, Jovanovic V, Van Tol HH. Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. J Neurochem. 1995; 65:1157-1165.
    • (1995) J Neurochem , vol.65 , pp. 1157-1165
    • Asghari, V.1    Sanyal, S.2    Buchwaldt, S.3    Paterson, A.4    Jovanovic, V.5    Van Tol, H.H.6
  • 63
    • 0032738792 scopus 로고    scopus 로고
    • Comparative pharmacological and functional analysis of the human dopamine D4.2 and D4.10 receptor variants
    • Jovanovic V, Guan HC, Van Tol HH. Comparative pharmacological and functional analysis of the human dopamine D4.2 and D4.10 receptor variants. Pharmacogenetics. 1999;9:561-568.
    • (1999) Pharmacogenetics , vol.9 , pp. 561-568
    • Jovanovic, V.1    Guan, H.C.2    Van Tol, H.H.3
  • 64
    • 0017613446 scopus 로고
    • Methylphenidate in hyperkinetic children: Differences in dose effects on learning and social behavior
    • Sprague RL, Sleator EK. Methylphenidate in hyperkinetic children: differences in dose effects on learning and social behavior. Science. 1977;198:1274-1276. (Pubitemid 8308550)
    • (1977) Science , vol.198 , Issue.4323 , pp. 1274-1276
    • Sprague, R.L.1    Sleator, E.K.2
  • 68
    • 32844466056 scopus 로고    scopus 로고
    • Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder [4]
    • DOI 10.1038/sj.mp.4001743, PII 4001743
    • Roman T, Polanczyk GV, Zeni C, Genro JP, Rohde LA, Hutz MH. Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder. Mol Psychiatry. 2006;11: 8-10. (Pubitemid 43251082)
    • (2006) Molecular Psychiatry , vol.11 , Issue.1 , pp. 8-10
    • Roman, T.1    Polanczyk, G.V.2    Zeni, C.3    Genro, J.P.4    Rohde, L.A.5    Hutz, M.H.6
  • 70
    • 0032896450 scopus 로고    scopus 로고
    • Additive effect of three noradrenergic genes (ADRA2A, ADRA2C, DBH) on attention-deficit hyperactivity disorder and learning disabilities in Tourette syndrome subjects
    • DOI 10.1034/j.1399-0004.1999.550304.x
    • Comings DE, Gade-Andavolu R, Gonzalez N, Blake H, Wu S, MacMurray JP. Additive effect of three noradrenergic genes (ADRA2a, ADRA2C, DBH) on attention-deficit hyperactivity disorder and learning disabilities in Tourette syndrome subjects. Clin Genet. 1999;55:160-172. (Pubitemid 29178733)
    • (1999) Clinical Genetics , vol.55 , Issue.3 , pp. 160-172
    • Comings, D.E.1    Gade-Andavolu, R.2    Gonzalez, N.3    Blake, H.4    Wu, S.5    MacMurray, J.P.6
  • 71
    • 57349087268 scopus 로고    scopus 로고
    • Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder
    • Mick E, Neale B, Middleton FA, McGough JJ, Faraone SV. Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1412-1418.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1412-1418
    • Mick, E.1    Neale, B.2    Middleton, F.A.3    McGough, J.J.4    Faraone, S.V.5
  • 75
    • 0030935347 scopus 로고    scopus 로고
    • Behavioral characteristics of DSM-IV ADHD subtypes in a school-based population
    • DOI 10.1023/A:1025775311259
    • Gaub M, Carlson CL. Behavioral characteristics of DSM-IV ADHD subtypes in a school-based population. J Abnorm Child Psychol. 1997;25:103-111. (Pubitemid 27169353)
    • (1997) Journal of Abnormal Child Psychology , vol.25 , Issue.2 , pp. 103-111
    • Gaub, M.1    Carlson, C.L.2
  • 76
    • 0029028366 scopus 로고
    • Comparison of diagnostic criteria for attention deficit disorders in a German elementary school sample
    • Baumgaertel A, Wolraich ML, Dietrich M. Comparison of diagnostic criteria for attention deficit disorders in a German elementary school sample. J Am Acad Child Adolesc Psychiatry. 1995; 34:629-638.
    • (1995) J Am Acad Child Adolesc Psychiatry , vol.34 , pp. 629-638
    • Baumgaertel, A.1    Wolraich, M.L.2    Dietrich, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.