Impaired Temporal Resolution of Visual Attention and Dopamine Beta Hydroxylase Genotype in Attention-Deficit/Hyperactivity Disorder

Biological Psychiatry

Volumn 60, Issue 10, 2006, Pages 1039-1045

  Bellgrove, Mark A ^a,b   Mattingley, Jason B ^a   Hawi, Ziarih ^b   Mullins, Celine ^b   Kirley, Aiveen ^b   Gill, Michael ^b   Robertson, Ian H ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

ADHD; attention; DBH; dopamine; genetics; noradrenaline

Indexed keywords

ADRENALIN; DOPAMINE; DOPAMINE BETA MONOOXYGENASE;

ADOLESCENT; ALLELE; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MALE; PRIORITY JOURNAL; VISION; VISUAL STIMULATION;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CASE-CONTROL STUDIES; CHILD; DOPAMINE BETA-HYDROXYLASE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; JUDGMENT; LINKAGE DISEQUILIBRIUM; MALE; PERCEPTUAL DISORDERS; PHOTIC STIMULATION; POLYMORPHISM, GENETIC; TIME FACTORS; TIME PERCEPTION;

EID: 33750433575     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2006.03.062     Document Type: Article

References (68)

1. Angold A., Predergast M., Cox A., Harrington R., Simonoff E., and Rutter M. The Child and Adolescent Psychiatric Assessment (CAPA). Psychol Med 25 (1995) 739-753
2. Aston-Jones G., Rajkowski J., Ivanova S., Usher M., and Cohen J. Neuromodulation and cognitive performance: Recent studies of noradrenergic locus ceruleus neurons in behaving monkeys. Adv Pharmacol 42 (1998) 755-759
3. Bellgrove M.A., Domschke K., Hawi Z., Kirley A., Mullins C., Robertson I.H., et al. The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD. Exp Brain Res 163 (2005) 352-360
4. Bellgrove M.A., Gill M., Hawi Z., Kirley A., and Robertson I.H. Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: Sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype. Neuropsychologia 43 13 (2005) 1847-1857
5. Bellgrove MA, Hawi Z, Gill M, Robertson IH (in press): The cognitive genetics of attention deficit hyperactivity disorder (ADHD): Sustained attention as a candidate phenotype. Cortex.
6. Bellgrove M.A., Hawi Z., Kirley A., Fitzgerald M., Gill M., and Robertson I.H. Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder. Neuropsychopharmacology 30 12 (2005) 2290-2297
7. Bellgrove M.A., Hawi Z., Lowe N., Kirley A., Robertson I.H., and Gill M. DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): Effects of associated alleles at the VNTR and -521 SNP. Am J Med Genet B Neuropsychiatr Genet 136 (2005) 81-86
8. Bhaduri N., Sinha S., Chattopadhyay A., Gangopadhyay P.K., Singh M., and Mukhopadhyay K.K. Analysis of polymorphisms in the dopamine beta hydroxylase gene: Association with attention deficit hyperactivity disorder in Indian children. Indian Pediatr 42 (2005) 123-129
9. Biederman J., Faraone S.V., Keenan K., Knee D., and Tsuang M.T. Family-genetic and psychosocial risk factors in DSM-III attention deficit disorder. J Am Acad Child Adolesc Psychiatry 29 (1990) 526-533
10. Brandon C.L., Marinelli M., and White F.J. Adolescent exposure to methylphenidate alters the activity of rat midbrain dopamine neurons. Biol Psychiatry 54 (2003) 1338-1344
11. Cadoret R.J., and Stewart M.A. An adoption study of attention deficit/hyperactivity/aggression and their relationship to adult antisocial personality. Compr Psychiatry 32 (1991) 73-82
12. Carter C.S., Krener P., Chaderjian M., Northcutt C., and Wolfe V. Asymmetrical visual-spatial attentional performance in ADHD: Evidence for a right hemispheric deficit. Biol Psychiatry 37 (1995) 789-797
13. Castellanos F.X., and Tannock R. Neuroscience of attention-deficit/hyperactivity disorder: The search for endophenotypes. Nat Rev Neurosci 3 (2002) 617-628
14. Chambers C.D., Payne J.M., Stokes M.G., and Mattingley J.B. Fast and slow parietal pathways mediate spatial attention. Nat Neurosci 7 (2004) 217-218
15. Conners C.K. Conners' Rating Scales -Revised: Technical Manual (1997), Multi-Health Systems Inc, New York
16. Conners C.K. Rating scales in attention deficit hyperactivity disorder: Use in assessment and treatment monitoring. J Clin Psychiatry 59 (1998) 24-30
17. Cooper A.C., Humphreys G.W., Hulleman J., Praamstra P., and Georgeson M. Transcranial magnetic stimulation to right parietal cortex modifies the attentional blink. Exp Brain Res 155 (2004) 24-29
18. Corbetta M., and Shulman G.L. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3 (2002) 201-215
19. Coull J.T., Frith C.D., Buchel C., and Nobre A.C. Orienting attention in time: Behavioural and neuroanatomical distinction between exogenous and endogenous shifts. Neuropsychologia 38 (2000) 808-819
20. Coull J.T., Nobre A.C., and Frith C.D. The noradrenergic alpha2 agonist clonidine modulates behavioural and neuroanatomical correlates of human attentional orienting and alerting. Cereb Cortex 11 (2001) 73-84
21. Coull J.T., Walsh V., Frith C.D., and Nobre A.C. Distinct neural substrates for visual search amongst spatial versus temporal distractors. Brain Res Cogn Brain Res 17 (2003) 368-379
22. Daly G., Hawi Z., Fitzgerald M., and Gill M. Mapping susceptibility loci in attention deficit hyperactivity disorder: Preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children. Mol Psychiatry 4 (1999) 192-196
23. Durston S., Fossella J.A., Casey B.J., Hulshoff Pol H.E., Galvan A., Schnack H.G., et al. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Mol Psychiatry 10 7 (2005) 678-685
24. Epstein J.N., Conners C.K., Erhardt D., March J.S., and Swanson J.M. Asymmetrical hemispheric control of visual-spatial attention in adults with attention deficit hyperactivity disorder. Neuropsychology 11 (1997) 467-473
25. Faraone S.V., Biederman J., and Milberger S. An exploratory study of ADHD among second-degree relatives of ADHD children. Biol Psychiatry 35 (1994) 398-402
26. Faraone S.V., Doyle A.E., Mick E., and Biederman J. Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder. Am J Psychiatry 158 (2001) 1052-1057
27. Foote S.L., and Morrison J.H. Extrathalamic modulation of cortical function. Annu Rev Neurosci 10 (1987) 67-95
28. Hawi Z., Kirley A., Lowe N., Fitzgerald M., and Gill M. Recent genetic advances in ADHD and diagnostic and therapeutic prospects. Expert Rev Neurother 3 (2003) 453-464
29. Hollingsworth D.E., McAuliffe S.P., and Knowlton B.J. Temporal allocation of visual attention in adult attention deficit hyperactivity disorder. J Cogn Neurosci 13 (2001) 298-305
30. Holmes J., Lawson D., Langley K., Fitzpatrick H., Trumper A., Pay H., et al. The Child Attention-Deficit Hyperactivity Disorder Teacher Telephone Interview (CHATTI): Reliability and validity. Br J Psychiatry 184 (2004) 74-78
31. Husain M., and Rorden C. Non-spatially lateralised mechanisms in hemispatial neglect. Nat Rev Neurosci 4 (2003) 26-36
32. Inkster B., Muglia P., Jain U., and Kennedy J.L. Linkage disequilibrium analysis of the dopamine beta-hydroxylase gene in persistent attention deficit hyperactivity disorder. Psychiatr Genet 14 (2004) 117-120
33. Iversen S.D. Behavioural effects of manipulation of basal ganglia neurotransmitters. Ciba Found Symp 107 (1984) 183-200
34. Kirley A., Hawi Z., Daly G., McCarron M., Mullins C., Millar N., et al. Dopaminergic system genes in ADHD: Toward a biological hypothesis. Neuropsychopharmacology 27 (2002) 607-619
35. Klimkeit E.I., Mattingley J.B., Sheppard D.M., Lee P., and Bradshaw J.L. Perceptual asymmetries in normal children and children with attention deficit/hyperactivity disorder. Brain Cogn 52 (2003) 205-215
36. Langley K., Marshall L., van den Bree M., Thomas H., Owen M., O'Donovan M., et al. Association of the dopamine d(4) receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD. Am J Psychiatry 161 (2004) 133-138
37. Levy F., Hay D., McStephen M., Wood C., and Waldman I. Attention-deficit hyperactivity disorder: A category or a continuum? Genetic analysis of a large-scale twin study. J Am Acad Child Adolesc Psychiatry 36 (1997) 737-744
38. Li C.S., Lin W.H., Chang H.L., and Hung Y.W. A psychophysical measure of attention deficit in children with attention-deficit/hyperactivity disorder. J Abnorm Psychol 113 (2004) 228-236
39. Loo S.K., Specter E., Smolen A., Hopfer C., Teale P.D., and Reite M.L. Functional effects of the DAT1 polymorphism on EEG measures in ADHD. J Am Acad Child Adolesc Psychiatry 42 (2003) 986-993
40. Marois R., Chun M.M., and Gore J.C. Neural correlates of the attentional blink. Neuron 28 (2000) 299-308
41. Nieuwenhuis S., Gilzenrat M.S., Holmes B.D., and Cohen J.D. The role of the locus coeruleus in mediating the attentional blink: A neurocomputational theory. J ExpPsychol Gen 134 3 (2005) 291-307
42. Nigg J.T., Swanson J.M., and Hinshaw S.P. Covert visual spatial attention in boys with attention deficit hyperactivity disorder: Lateral effects, methylphenidate response, and results for parents. Neuropsychologia 35 (1997) 165-176
43. Parasuraman R., Greenwood P., Kumar R., and Fossella J. Beyond heritability: Neurotransmitter genes differentially modulate visuospatial attention and working memory. Psychol Sci 16 (2005) 200-207
44. Pliszka S.R., McCracken J.T., and Maas J.W. Catecholamines in attention-deficit hyperactivity disorder: Current perspectives. J Am Acad Child Adolesc Psychiatry 35 (1996) 264-272
45. Posner M., Walker J., Friedrich F.J., and Rafal R. Effects of parietal injury on covert orienting of attention. J Neurosci 4 (1984) 1863-1874
46. Posner M.I., and Cohen Y. Components of visual orienting. In: Bouma H., and Bouwhuis D.G. (Eds). Attention and Performance, vol 10 (1984), Lawrence Erlbaum, London
47. Posner M.I., and Peterson S.E. The attention system of the human brain. Annu Rev Neurosci 13 (1990) 35-42
48. Raymond J.E., Shapiro K.L., and Arnell K.M. Similarity determines the attentional blink. J Exp Psychol Hum Percept Perform 21 (1995) 653-662
49. Robertson I.H., and Marshall J.C. Unilateral Neglect: Clinical and Experimental Studies (1993), Lawrence Erlbaum and Associates, Hillsdale, NJ
50. Rogeness G.A., Maas J.W., Javors M.A., Macedo C.A., Fischer C., and Harris W.R. Attention deficit disorder symptoms and urine catecholamines. Psychiatry Res 27 (1989) 241-251
51. Roman T., Schmitz M., Polanczyk G.V., Eizirik M., Rohde L.A., and Hutz M.H. Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine-beta-hydroxylase gene. Am J Med Genet 114 (2002) 154-158
52. Rorden C., Mattingley J.B., Karnath H.-O., and Driver J. Visual extinction and prior entry: Impaired perception of temporal order with intact motion perception after unilateral parietal damage. Neuropsychologia 35 (1997) 421-433
53. Shapiro K.L., Raymond J.E., and Arnell K.M. Attention to visual pattern information produces the attentional blink in rapid serial visual presentation. J Exp Psychol Hum Percept Perform 20 (1994) 357-371
54. Sheppard D.M., Bradshaw J.L., Mattingley J.B., and Lee P. Effects of stimulant medication on the lateralisation of line bisection judgements of children with attention deficit hyperactivity disorder. J Neurol NeurosurgPsychiatry 66 (1999) 57-63
55. Silk T., Vance A., Rinehart N., Egan G., O'Boyle M., Bradshaw J.L., et al. Fronto-parietal activation in attention deficit hyperactivity disorder, combined type: Functional magnetic resonance imaging study. Br J Psychiatry 187 (2005) 282-283
56. Smith K.M., Daly M., Fischer M., Yiannoutsos C.T., Bauer L., Barkley R., et al. Association of the dopamine beta hydroxylase gene with attention deficit hyperactivity disorder: Genetic analysis of the Milwaukee longitudinal study. Am J Med Genet B Neuropsychiatr Genet 119 (2003) 77-85
57. Sowell E.R., Thompson P.M., Welcome S.E., Henkenius A.L., Toga A.W., and Peterson B.S. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362 (2003) 1699-1707
58. Swanson J.M., Posner M., Potkin S., Bonforte S., Youpa D., Fiore C., et al. Activating tasks for the study of visual-spatial attention in ADHD children: A cognitive anatomic approach. J Child Neurol 6 suppl (1991) S119-S127
59. Thapar A., Hervas A., and McGuffin P. Childhood hyperactivity scores are highly heritable and show sibling competition effects: Twin study evidence. Behav Genet 25 (1995) 537-544
60. Voeller K.K., and Heilman K.M. Attention deficit disorder in children: A neglect syndrome?. Neurology 38 (1988) 806-808
61. Waldman I.D. Statistical approaches to complex phenotypes: Evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder. Biol Psychiatry 57 (2005) 1347-1356
62. Waldman I.D., Robinson B.F., and Rowe D.C. A logistic regression based extension of the TDT for continuous and categorical traits. Ann Hum Genet 63 Pt 4 (1999) 329-340
63. Wigg K., Zai G., Schachar R., Tannock R., Roberts W., Malone M., et al. Attention deficit hyperactivity disorder and the gene for dopamine beta-hydroxylase. Am J Psychiatry 159 (2002) 1046-1048
64. Witte E.A., and Marrocco R.T. Alteration of brain noradrenergic activity in rhesus monkeys affects the alerting component of covert orienting. Psychopharmacology (Berl) 132 (1997) 315-323
65. Wood C., Maruff P., Levy F., Farrow M., and Hay D. Covert orienting of visual spatial attention in attention deficit hyperactivity disorder: Does comorbidity make a difference?. Arch Clin Neuropsychol 14 (1999) 179-189
66. Zabetian C.P., Anderson G.M., Buxbaum S.G., Elston R.C., Ichinose H., Nagatsu T., et al. A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus. Am J Hum Genet 68 (2001) 515-522
67. Zhang H.B., Wang Y.F., Li J., Wang B., and Yang L. [Association of dopamine beta-hydroxylase polymorphism with attention deficit hyperactivity disorder in children]. Beijing Da Xue Xue Bao 36 (2004) 290-293
68. Zhang H.B., Wang Y.F., Li J., Wang B., and Yang L. [Association between dopamine beta hydroxylase gene and attention deficit hyperactivity disorder complicated with disruptive behavior disorder]. Zhonghua Er Ke Za Zhi 43 (2005) 26-30