Experimental and in silico investigation of population heterogeneity in continuous Sachharomyces cerevisiae scale-down fermentation in a two-compartment setup

Journal of Chemical Technology and Biotechnology

Volumn 90, Issue 2, 2015, Pages 324-340

  Heins, Anna Lena ^a   Lencastre Fernandes, Rita ^a   Gernaey, Krist V ^a   Lantz, Anna Eliasson ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Continuous scale down reactor; Mathematical modeling; Population balance model; Population heterogeneity; Reporter strain; Two compartment bioreactor

Indexed keywords

BIOREACTORS; CELL CULTURE; CELL PROLIFERATION; CELLS; CYTOLOGY; GLUCOSE; MATHEMATICAL MODELS; OXYGEN; OXYGEN SUPPLY; POPULATION STATISTICS; STRAIN;

CONTINUOUS CULTIVATION; CONTINUOUS SCALE; ENVIRONMENTAL CONDITIONS; LABORATORY-SCALE REACTOR; LARGE SCALE BIOREACTORS; LARGE SCALE CONDITIONS; POPULATION BALANCE MODELING; POPULATION HETEROGENEITY;

POPULATION DISTRIBUTION;

ALCOHOL; GLUCOSE; OXYGEN;

ARTICLE; BIOMASS; CELL POPULATION; CELL SIZE; CHEMOSTAT; COMPARTMENT MODEL; CONTINUOUS FERMENTATION; CONTINUOUS STIRRED TANK REACTOR; DILUTION; FLUORESCENCE; FUNGAL STRAIN; MATHEMATICAL MODEL; NONHUMAN; QUANTITATIVE ANALYSIS; SACCHAROMYCES CEREVISIAE;

EID: 84920895427     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.4532     Document Type: Article

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