Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

American Journal of Human Genetics

Volumn 96, Issue 1, 2015, Pages 5-20

  Glubb, Dylan M ^a   Maranian, Mel J ^b   Michailidou, Kyriaki ^b   Pooley, Karen A ^b   Meyer, Kerstin B ^b   Kar, Siddhartha ^b   Carlebur, Saskia ^b   O'Reilly, Martin ^b   Betts, Joshua A ^a,c   Hillman, Kristine M ^a   Kaufmann, Susanne ^a   Beesley, Jonathan ^a   Canisius, Sander ^d   Hopper, John L ^e   Southey, Melissa C ^f   Tsimiklis, Helen ^f   Apicella, Carmel ^f   Schmidt, Marjanka K ^d   Broeks, Annegien ^d   Hogervorst, Frans B ^d   Van Der Schoot, C Ellen ^g   Muir, Kenneth ^h,i   Lophatananon, Artitaya ^h   Stewart Brown, Sarah ^h   Siriwanarangsan, Pornthep ^j   Fasching, Peter A ^k,l   Ruebner, Matthias ^k   Ekici, Arif B ^k   Beckmann, Matthias W ^k   Peto, Julian ^m   Dos Santos Silva, Isabel ^m   Fletcher, Olivia ⁿ   Johnson, Nichola ⁿ   Pharoah, Paul D P ^b   Bolla, Manjeet K ^b   Wang, Qin ^b   Dennis, Joe ^b   Sawyer, Elinor J ^o   Tomlinson, Ian ^p   Kerin, Michael J ^q   Miller, Nicola ^q   Burwinkel, Barbara ^r   Marme, Frederik ^r   Yang, Rongxi ^r,s   Surowy, Harald ^r,s   Guénel, Pascal ^t,u   Truong, Thérèse ^t,u   Menegaux, Florence ^t,u   Sanchez, Marie ^t,u   Bojesen, Stig E ^v,w   Nordestgaard, Børge G ^v,w   Nielsen, Sune F ^v   Flyger, Henrik ^v   González Neira, Anna ^x   Benitez, Javier ^x,y   Zamora, M Pilar ^z   Arias Perez, Jose Ignacio ^aa   Anton Culver, Hoda ^ab   Neuhausen, Susan L ^ac   Brenner, Hermann ^s   Dieffenbach, Aida Karina ^s   Arndt, Volker ^s   Stegmaier, Christa ^ad   Meindl, Alfons ^ae   Schmutzler, Rita K ^af,ag   Brauch, Hiltrud ^ah,ai   Ko, Yon Dschun ^aj   Brüning, Thomas ^ak,al   Nevanlinna, Heli ^am   Muranen, Taru A ^am   Aittomäki, Kristiina ^an   Blomqvist, Carl ^am   Matsuo, Keitaro ^ao   Ito, Hidemi ^ap   Iwata, Hiroji ^ap   Tanaka, Hideo ^ap   Dörk, Thilo ^aq   Bogdanova, Natalia V ^aq   Helbig, Sonja ^aq   Lindblom, Annika ^ar   Margolin, Sara ^ar   Mannermaa, Arto ^as,at   Kataja, Vesa ^as,at   Kosma, Veli Matti ^as,at   Hartikainen, Jaana M ^as,at   Wu, Anna H ^au,av   Tseng, Chiu Chen ^av   Van Den Berg, David ^av   Stram, Daniel O ^av   Lambrechts, Diether ^aw,ax   Zhao, Hui ^aw,ax   Weltens, Caroline ^ay   Van Limbergen, Erik ^ay   Chang Claude, Jenny ^s   Flesch Janys, Dieter ^al   Rudolph, Anja ^s   Seibold, Petra ^s   Radice, Paolo ^az   Peterlongo, Paolo ^ba   Barile, Monica ^bb   Capra, Fabio ^ba,bc   Couch, Fergus J ^bd   Olson, Janet E ^bd   Hallberg, Emily ^bd   Vachon, Celine ^bd   Giles, Graham G ^d,be   Milne, Roger L ^d,be   McLean, Catriona ^bf   Haiman, Christopher A ^av   Henderson, Brian E ^av   Schumacher, Fredrick ^av   Le Marchand, Loic ^bg   Simard, Jacques ^bh   Goldberg, Mark S ^bi,bj   Labrèche, France ^bk   Dumont, Martine ^bh   Teo, Soo Hwang ^bl,bm   Yip, Cheng Har ^bm   See, Mee Hoong ^bm   Cornes, Belinda ^bn   Cheng, Ching Yu ^bn   Ikram, M Kamran ^bn   Kristensen, Vessela ^{bo,bp,bq,br,bs,bt,bu,bv}   Zheng, Wei ^bw   Halverson, Sandra L ^bw   Shrubsole, Martha ^bw   Long, Jirong ^bw   Winqvist, Robert ^bx   Pylkäs, Katri ^bx   Jukkola Vuorinen, Arja ^by   Kauppila, Saila ^by   Andrulis, Irene L ^bz,ca   Knight, Julia A ^bz,cb   Glendon, Gord ^bz   Tchatchou, Sandrine ^bz   Devilee, Peter ^cc   Tollenaar, Robert A E M ^cc   Seynaeve, Caroline ^cd   Van Asperen, Christi J ^cc   García Closas, Montserrat ⁿ   Figueroa, Jonine ^ce   Chanock, Stephen J ^ce   Lissowska, Jolanta ^cf   Czene, Kamila ^ar   Klevebring, Daniel ^ar   Darabi, Hatef ^ar   Eriksson, Mikael ^ar   Hooning, Maartje J ^cg   Hollestelle, Antoinette ^cg   Martens, John W M ^cg   Collée, J Margriet ^ch   Hall, Per ^ar   Li, Jingmei ^ci   Humphreys, Keith ^ar   Shu, Xiao Ou ^bw   Lu, Wei ^cj   Gao, Yu Tang ^ck   Cai, Hui ^bw   Cox, Angela ^cl   Cross, Simon S ^cl   Reed, Malcolm W R ^cl   Blot, William ^bw,cm   Signorello, Lisa B ^bw,cm   Cai, Qiuyin ^bw   Shah, Mitul ^b   Ghoussaini, Maya ^b   Kang, Daehee ^cn,co   Choi, Ji Yeob ^cn,co   Park, Sue K ^cn,co   Noh, Dong Young ^cp   Hartman, Mikael ^cq   Miao, Hui ^cq   Lim, Wei Yen ^cq   Tang, Anthony ^cq   Hamann, Ute ^s   Torres, Diana ^s,cr   Jakubowska, Anna ^cs   Lubinski, Jan ^cs   Jaworska, Katarzyna ^cs   Durda, Katarzyna ^cs   Sangrajrang, Suleeporn ^ct   Gaborieau, Valerie ^cu   Brennan, Paul ^cu   McKay, James ^cu   Olswold, Curtis ^bd   Slager, Susan ^bd   Toland, Amanda E ^cv   Yannoukakos, Drakoulis ^cw   Shen, Chen Yang ^cx,cy   Wu, Pei Ei ^cx   Yu, Jyh Cherng ^cz   Hou, Ming Feng ^da   Swerdlow, Anthony ⁿ   Ashworth, Alan ⁿ   Orr, Nick ⁿ   Jones, Michael ⁿ   Pita, Guillermo ^x   Alonso, M Rosario ^x   Álvarez, Nuria ^x   Herrero, Daniel ^x   Tessier, Daniel C ^bj   Vincent, Daniel ^bj   Bacot, Francois ^bj   Luccarini, Craig ^b   Baynes, Caroline ^b   Ahmed, Shahana ^b   Healey, Catherine S ^b   Brown, Melissa A ^c   Ponder, Bruce A J ^b   Chenevix Trench, Georgia ^a   Thompson, Deborah J ^b   Edwards, Stacey L ^a,c   Easton, Douglas F ^b   Dunning, Alison M ^b   French, Juliet D ^a,c   more..

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g SANQUIN RESEARCH   (Netherlands)

^h UNIVERSITY OF WARWICK   (United Kingdom)

ⁱ UNIVERSITY OF MANCHESTER   (United Kingdom)

^j MINISTRY OF PUBLIC HEALTH   (Thailand)

^k UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^l UNIVERSITY OF CALIFORNIA   (United States)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^o GUY S HOSPITAL   (United Kingdom)

^p UNIVERSITY OF OXFORD   (United Kingdom)

^q UNIVERSITY HOSPITAL GALWAY   (Ireland)

^r UNIVERSITY OF HEIDELBERG   (Germany)

^s GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^t INSERM   (France)

^u CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^v GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^w UNIVERSITY OF COPENHAGEN   (Denmark)

^x Centro Nacional de Investigaciones Oncológicas   (Spain)

^y Centro de Investigación en Red de Enfermedades Raras   (Spain)

^z HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^aa HOSPITAL MONTE NARANCO   (Spain)

^ab UNIVERSITY OF CALIFORNIA   (United States)

^ac CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^ad Saarland Cancer Registry   (Germany)

^ae TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^af UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^ag UNIVERSITY OF COLOGNE   (Germany)

^ah UNIVERSITY OF TÜBINGEN   (Germany)

^ai DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^aj Johanniter Krankenhaus   (Germany)

^ak RUHR UNIVERSITY BOCHUM   (Germany)

^al UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^am UNIVERSITY OF HELSINKI   (Finland)

^an HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^ao KYUSHU UNIVERSITY   (Japan)

^ap AICHI CANCER CENTER HOSPITAL   (Japan)

^aq HANNOVER MEDICAL SCHOOL   (Germany)

^ar KAROLINSKA INSTITUTE   (Sweden)

^as UNIVERSITY OF EASTERN FINLAND   (Finland)

^at KUOPIO UNIVERSITY HOSPITAL   (Finland)

^au PETER MACCALLUM CANCER CENTRE   (Australia)

^av UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^aw UNIVERSITY OF LEUVEN   (Belgium)

^ax DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^ay UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^az DEPARTMENT OF NEUROSURGERY   (Italy)

^ba Campus Istituto FIRC di oncologia molecolare and Istituto Europeo di Oncologia   (Italy)

^bb EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^bc Istituto Fondazione Italiana per la Ricerca sul Cancro di Oncologia Molecolare ^*  (Italy)

^bd MAYO CLINIC   (United States)

^be CANCER EPIDEMIOLOGY CENTRE   (Australia)

^bf ALFRED HEALTH   (Australia)

^bg UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^bh Université Laval   (Canada)

^bi ROYAL VICTORIA HOSPITAL   (Canada)

^bj MCGILL UNIVERSITY   (Canada)

^bk UNIVERSITÉ DE MONTRÉAL   (Canada)

^bl CANCER RESEARCH INITIATIVES FOUNDATION   (Malaysia)

^bm UNIVERSITY MALAYA MEDICAL CENTRE   (Malaysia)

^bn NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^bo UNIVERSITY OF OSLO   (Norway)

^bp OSLO UNIVERSITY HOSPITAL   (Norway)

^bq UNIVERSITY OF BERGEN   (Norway)

^br UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^bs AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^bt HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^bu UNIVERSITY OF TROMSØ   (Norway)

^bv ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^bw VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^bx UNIVERSITY OF OULU   (Finland)

^by OULU UNIVERSITY HOSPITAL   (Finland)

^bz MOUNT SINAI HOSPITAL   (Canada)

^ca UNIVERSITY OF TORONTO   (Canada)

^cb UNIVERSITY OF TORONTO   (Canada)

^cc LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^cd NETHERLANDS CANCER INSTITUTE   (Netherlands)

^ce NATIONAL CANCER INSTITUTE   (United States)

^cf INSTITUTE OF ONCOLOGY   (Poland)

^cg ERASMUS MC CANCER INSTITUTE   (Netherlands)

^ch ERASMUS MEDICAL CENTER   (Netherlands)

^ci GENOME INSTITUTE OF SINGAPORE   (Singapore)

^cj Disease Control and Prevention Center of Changning Area   (China)

^ck SHANGHAI CANCER INSTITUTE   (China)

^cl UNIVERSITY OF SHEFFIELD   (United Kingdom)

^cm INTERNATIONAL EPIDEMIOLOGY INSTITUTE   (United States)

^cn Seoul National University College of Medicine   (South Korea)

^co Seoul National University   (South Korea)

^cp Seoul National University Bundang Hospital   (South Korea)

^cq NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^cr PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^cs POMERANIAN MEDICAL UNIVERSITY   (Poland)

^ct NATIONAL CANCER INSTITUTE   (Thailand)

^cu INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^cv OHIO STATE UNIVERSITY   (United States)

^cw INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^cx INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^cy CHINA MEDICAL UNIVERSITY   (Taiwan)

^cz TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^da KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; MAP3K1 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; MAP3K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1;

ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 5Q; CHROMOSOME MAP; CONTROLLED STUDY; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; EUROPEAN; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; SINGLE NUCLEOTIDE POLYMORPHISM; ANCESTRY GROUP; BREAST TUMOR; CASE CONTROL STUDY; CHROMOSOME 5; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; MCF 7 CELL LINE; METABOLISM; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; RISK FACTOR; TUMOR CELL LINE;

ALLELES; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 5; CONTINENTAL POPULATION GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; MAP KINASE KINASE KINASE 1; MCF-7 CELLS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; QUANTITATIVE TRAIT LOCI; RISK FACTORS;

EID: 84920818376     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2014.11.009     Document Type: Article

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