The Generation of Definitive Endoderm from Human Embryonic Stem Cells is Initially Independent from Activin A but Requires Canonical Wnt-Signaling

Stem Cell Reviews and Reports

Volumn 10, Issue 4, 2014, Pages 480-493

  Naujok, Ortwin ^a   Diekmann, Ulf ^a   Lenzen, Sigurd ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Definitive endoderm; GSK3beta inhibition; Human ESCs; Primitive streak; Wnt catenin pathway

Indexed keywords

6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ACTIVIN; ACTIVIN A; GLYCOGEN SYNTHASE KINASE 3; MESSENGER RNA; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; EMBRYONIC STEM CELL; ENDODERM; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENETICS; HUMAN; MESODERM; METABOLISM; PANCREAS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVINS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; ENDODERM; FLOW CYTOMETRY; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOENZYME TECHNIQUES; MESODERM; PANCREAS; PYRIDINES; PYRIMIDINES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

EID: 84920806324     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-014-9509-0     Document Type: Article

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