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Volumn 91, Issue 1-2, 2000, Pages 249-258

Brachyury is a target gene of the Wnt/β-catenin signaling pathway

Author keywords

Brachyury; Embryonic stem cells; Mesoderm formation; Mouse embryonic development; Wnt catenin signaling pathway

Indexed keywords

BETA CATENIN; GREEN FLUORESCENT PROTEIN;

EID: 0033994197     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(99)00309-3     Document Type: Article
Times cited : (254)

References (51)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H., Bauer A., Stappert J., Kispert A., Kemler R. beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16:1997;3797-3804.
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 2
    • 0031718204 scopus 로고    scopus 로고
    • Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer
    • Ben-Ze'ev A., Geiger B. Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer. Curr. Opin. Cell Biol. 10:1998;629-639.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 629-639
    • Ben-Ze'ev, A.1    Geiger, B.2
  • 3
    • 0030930442 scopus 로고    scopus 로고
    • A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
    • Brannon M., Gomperts M., Sumoy L., Moon R.T., Kimelman D. A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev. 11:1997;2359-2370.
    • (1997) Genes Dev. , vol.11 , pp. 2359-2370
    • Brannon, M.1    Gomperts, M.2    Sumoy, L.3    Moon, R.T.4    Kimelman, D.5
  • 4
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan K.M., Nusse R. Wnt signaling: a common theme in animal development. Genes Dev. 11:1997;3286-3305.
    • (1997) Genes Dev. , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 5
    • 0023392945 scopus 로고
    • High-efficiency transformation of mammalian cells by plasmid DNA
    • Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:1987;2725-2745.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2725-2745
    • Chen, C.1    Okayama, H.2
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 7
    • 0029896596 scopus 로고    scopus 로고
    • Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation
    • Clements D., Taylor H.C., Herrmann B.G., Stott D. Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mech. Dev. 56:1996;139-149.
    • (1996) Mech. Dev. , vol.56 , pp. 139-149
    • Clements, D.1    Taylor, H.C.2    Herrmann, B.G.3    Stott, D.4
  • 8
    • 0032516088 scopus 로고    scopus 로고
    • Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
    • Crease D.J., Dyson S., Gurdon J.B. Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression. Proc. Natl. Acad. Sci. USA. 8:1998;4398-4403.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.8 , pp. 4398-4403
    • Crease, D.J.1    Dyson, S.2    Gurdon, J.B.3
  • 9
    • 0344820773 scopus 로고    scopus 로고
    • Wnt3a-/ - Like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice
    • Galceran J., Fariñas I., Depew M.J., Clevers H., Grosschedl R. Wnt3a-/ - like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev. 13:1999;709-717.
    • (1999) Genes Dev , vol.13 , pp. 709-717
    • Galceran, J.1    Fariñas, I.2    Depew, M.J.3    Clevers, H.4    Grosschedl, R.5
  • 10
    • 0344500702 scopus 로고    scopus 로고
    • Keeping a close eye on Wnt-1/wg signaling in Xenopus
    • Gradl D., Kühl M., Wedlich D. Keeping a close eye on Wnt-1/wg signaling in Xenopus. Mech. Dev. 86:1999;3-15.
    • (1999) Mech. Dev. , vol.86 , pp. 3-15
    • Gradl, D.1    Kühl, M.2    Wedlich, D.3
  • 11
    • 0344171934 scopus 로고    scopus 로고
    • The Wnt/Wg signal transducer beta-catenin controls fibronectin expression
    • Gradl D., Kühl M., Wedlich D. The Wnt/Wg signal transducer beta-catenin controls fibronectin expression. Mol. Cell. Biol. 19:1999;5576-5587.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5576-5587
    • Gradl, D.1    Kühl, M.2    Wedlich, D.3
  • 12
    • 0031666549 scopus 로고    scopus 로고
    • Propagation and localization of Wnt signaling
    • Gumbiner B.M. Propagation and localization of Wnt signaling. Curr. Opin. Genet. Dev. 8:1998;430-435.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 430-435
    • Gumbiner, B.M.1
  • 14
    • 0031149476 scopus 로고    scopus 로고
    • Activation of the Wnt signaling pathway: A molecular mechanism for lithium action
    • Hedgepeth C.M., Conrad L.J., Zhang J., Huang H.C., Lee V.M., Klein P.S. Activation of the Wnt signaling pathway: a molecular mechanism for lithium action. Dev. Biol. 185:1997;82-91.
    • (1997) Dev. Biol. , vol.185 , pp. 82-91
    • Hedgepeth, C.M.1    Conrad, L.J.2    Zhang, J.3    Huang, H.C.4    Lee, V.M.5    Klein, P.S.6
  • 15
    • 0025062325 scopus 로고
    • Cloning of the T gene required in mesoderm formation in the mouse
    • Herrmann B.G., Labeit S., Poustka A., King T.R., Lehrach H. Cloning of the T gene required in mesoderm formation in the mouse. Nature. 343:1990;617-622.
    • (1990) Nature , vol.343 , pp. 617-622
    • Herrmann, B.G.1    Labeit, S.2    Poustka, A.3    King, T.R.4    Lehrach, H.5
  • 16
    • 0030272281 scopus 로고    scopus 로고
    • Cadherins and catenins in development
    • Huber O., Bierkamp C., Kemler R. Cadherins and catenins in development. Mech. Dev. 8:1996;685-691.
    • (1996) Mech. Dev. , vol.8 , pp. 685-691
    • Huber, O.1    Bierkamp, C.2    Kemler, R.3
  • 17
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
    • Huber O., Korn R., McLaughlin J., Ohsugi M., Herrmann B.G., Kemler R. Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59:1996;3-10.
    • (1996) Mech. Dev. , vol.59 , pp. 3-10
    • Huber, O.1    Korn, R.2    McLaughlin, J.3    Ohsugi, M.4    Herrmann, B.G.5    Kemler, R.6
  • 18
    • 0028572556 scopus 로고
    • E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton
    • Hulsken J., Birchmeier W., Behrens J. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J. Cell Biol. 127:1994;2061-2069.
    • (1994) J. Cell Biol. , vol.127 , pp. 2061-2069
    • Hulsken, J.1    Birchmeier, W.2    Behrens, J.3
  • 19
    • 0032576777 scopus 로고    scopus 로고
    • Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
    • Jiang J., Struhl G. Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature. 391:1998;493-496.
    • (1998) Nature , vol.391 , pp. 493-496
    • Jiang, J.1    Struhl, G.2
  • 20
    • 0027185632 scopus 로고
    • From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
    • Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9:1993;317-321.
    • (1993) Trends Genet. , vol.9 , pp. 317-321
    • Kemler, R.1
  • 21
    • 0031766557 scopus 로고    scopus 로고
    • Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
    • Kispert A., Vainio S., McMahon A.P. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development. 125:1998;4225-4234.
    • (1998) Development , vol.125 , pp. 4225-4234
    • Kispert, A.1    Vainio, S.2    McMahon, A.P.3
  • 25
    • 0030668506 scopus 로고    scopus 로고
    • The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins
    • Latinkic B.V., Umbhauer M., Neal K.A., Lerchner W., Smith J.C., Cunliffe V. The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev. 11:1997;3265-3276.
    • (1997) Genes Dev , vol.11 , pp. 3265-3276
    • Latinkic, B.V.1    Umbhauer, M.2    Neal, K.A.3    Lerchner, W.4    Smith, J.C.5    Cunliffe, V.6
  • 26
    • 0031453354 scopus 로고    scopus 로고
    • The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer
    • Laurent M.N., Blitz I.L., Hashimoto C., Rothbacher U., Cho K.W. The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer. Development. 124:1997;4905-4916.
    • (1997) Development , vol.124 , pp. 4905-4916
    • Laurent, M.N.1    Blitz, I.L.2    Hashimoto, C.3    Rothbacher, U.4    Cho, K.W.5
  • 28
    • 0032867869 scopus 로고    scopus 로고
    • Direct regulation of the Xenopus engrailed-2 promoter by the Wnt signaling pathway, and a molecular screen for Wnt-responsive genes, confirm a role for Wnt signaling during neural patterning in Xenopus
    • McGrew L.L., Takemura K.-I., Bates R., Moon R.T. Direct regulation of the Xenopus engrailed-2 promoter by the Wnt signaling pathway, and a molecular screen for Wnt-responsive genes, confirm a role for Wnt signaling during neural patterning in Xenopus. Mech. Dev. 87:1999;21-31.
    • (1999) Mech. Dev. , vol.87 , pp. 21-31
    • McGrew, L.L.1    Takemura, K.-I.2    Bates, R.3    Moon, R.T.4
  • 29
    • 18744425721 scopus 로고    scopus 로고
    • LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter
    • McKendry R., Hsu S.C., Harland R.M., Grosschedl R. LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev. Biol. 192:1997;420-431.
    • (1997) Dev. Biol. , vol.192 , pp. 420-431
    • McKendry, R.1    Hsu, S.C.2    Harland, R.M.3    Grosschedl, R.4
  • 30
    • 0026573580 scopus 로고
    • A general and fast method to generate multiple site directed mutations
    • Mikaelian I., Sergeant A. A general and fast method to generate multiple site directed mutations. Nucleic Acids Res. 20:1992;376.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 376
    • Mikaelian, I.1    Sergeant, A.2
  • 31
    • 0032128173 scopus 로고    scopus 로고
    • From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
    • Moon R.T., Kimelman D. From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus. BioEssays. 20:1998;536-545.
    • (1998) BioEssays , vol.20 , pp. 536-545
    • Moon, R.T.1    Kimelman, D.2
  • 32
    • 0031128225 scopus 로고    scopus 로고
    • WNTs modulate cell fate and behavior during vertebrate development
    • Moon R.T., Brown J.D., Torres M. WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 13:1997;157-162.
    • (1997) Trends Genet. , vol.13 , pp. 157-162
    • Moon, R.T.1    Brown, J.D.2    Torres, M.3
  • 33
    • 0028987249 scopus 로고
    • Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • Munemitsu S., Albert I., Souza B., Rubinfeld B., Polakis P. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. USA. 92:1995;3046-3050.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 34
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse R., Varmus H.E. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell. 31:1982;99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 35
    • 0030779038 scopus 로고    scopus 로고
    • Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin
    • Orford K., Crockett C., Jensen J.P., Weissman A.M., Byers S.W. Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. J. Biol. Chem. 272:1997;24735-24738.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24735-24738
    • Orford, K.1    Crockett, C.2    Jensen, J.P.3    Weissman, A.M.4    Byers, S.W.5
  • 36
    • 0032891720 scopus 로고    scopus 로고
    • E-Cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation
    • Orsulic S., Huber O., Aberle H., Arnold S., Kemler R. E-Cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J. Cell Sci. 112:1999;1237-1245.
    • (1999) J. Cell Sci. , vol.112 , pp. 1237-1245
    • Orsulic, S.1    Huber, O.2    Aberle, H.3    Arnold, S.4    Kemler, R.5
  • 37
    • 0024451982 scopus 로고
    • The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
    • Ozawa M., Baribault H., Kemler R. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8:1989;1711-1717.
    • (1989) EMBO J. , vol.8 , pp. 1711-1717
    • Ozawa, M.1    Baribault, H.2    Kemler, R.3
  • 39
    • 0030944065 scopus 로고    scopus 로고
    • Cancer - beta-catenin as oncogene - The smoking gun
    • Peifer M. Cancer - beta-catenin as oncogene - the smoking gun. Science. 275:1997;1752-1753.
    • (1997) Science , vol.275 , pp. 1752-1753
    • Peifer, M.1
  • 40
    • 0030979996 scopus 로고    scopus 로고
    • LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic
    • Riese J., Yu X., Munnerlyn A., Eresh S., Hsu S.C., Grosschedl R., Bienz M. LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell. 88:1997;777-787.
    • (1997) Cell , vol.88 , pp. 777-787
    • Riese, J.1    Yu, X.2    Munnerlyn, A.3    Eresh, S.4    Hsu, S.C.5    Grosschedl, R.6    Bienz, M.7
  • 41
    • 0029669950 scopus 로고    scopus 로고
    • A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
    • Robbins P.F., El-Gamil M., Li Y.F., Kawakami Y., Loftus D., Appella E., Rosenberg S.A. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J. Exp. Med. 183:1996;1185-1192.
    • (1996) J. Exp. Med. , vol.183 , pp. 1185-1192
    • Robbins, P.F.1    El-Gamil, M.2    Li, Y.F.3    Kawakami, Y.4    Loftus, D.5    Appella, E.6    Rosenberg, S.A.7
  • 42
    • 0028953279 scopus 로고
    • The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin
    • Rubinfeld B., Souza B., Albert I., Munemitsu S., Polakis P. The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin. J. Biol. Chem. 270:1995;5549-5555.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5549-5555
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3    Munemitsu, S.4    Polakis, P.5
  • 43
  • 45
    • 0023256867 scopus 로고
    • Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells
    • Smith A.G., Hooper M.L. Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev. Biol. 121:1987;1-9.
    • (1987) Dev. Biol. , vol.121 , pp. 1-9
    • Smith, A.G.1    Hooper, M.L.2
  • 46
    • 0033119649 scopus 로고    scopus 로고
    • T-box genes: What they do and how they do it
    • Smith J. T-box genes: what they do and how they do it. Trends Genet. 15:1999;154-158.
    • (1999) Trends Genet. , vol.15 , pp. 154-158
    • Smith, J.1
  • 48
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O., McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 398:1999;422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 49
    • 0032904850 scopus 로고    scopus 로고
    • Regulation of ribosomal S6 protein kinase-p90(rsk), glycogen synthase kinase 3, and beta-catenin in early Xenopus development
    • Torres M.A., Eldar-Finkelman H., Krebs E.G., Moon R.T. Regulation of ribosomal S6 protein kinase-p90(rsk), glycogen synthase kinase 3, and beta-catenin in early Xenopus development. Mol. Cell. Biol. 19:1999;1427-1437.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1427-1437
    • Torres, M.A.1    Eldar-Finkelman, H.2    Krebs, E.G.3    Moon, R.T.4
  • 50
    • 0025054992 scopus 로고
    • Expression pattern of the mouse T gene and its role in mesoderm formation
    • Wilkinson D.G., Bhatt S., Herrmann B.G. Expression pattern of the mouse T gene and its role in mesoderm formation. Nature. 343:1990;657-659.
    • (1990) Nature , vol.343 , pp. 657-659
    • Wilkinson, D.G.1    Bhatt, S.2    Herrmann, B.G.3
  • 51
    • 0029683606 scopus 로고    scopus 로고
    • The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in xenopus embryos by glycogen synthase kinase 3
    • Yost C., Torres M., Miller R.R., Huang E., Kimelman D., Moon R.T. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in xenopus embryos by glycogen synthase kinase 3. Genes Dev. 10:1996;1443-1454.
    • (1996) Genes Dev. , vol.10 , pp. 1443-1454
    • Yost, C.1    Torres, M.2    Miller, R.R.3    Huang, E.4    Kimelman, D.5    Moon, R.T.6


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