Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis

Journal of Lipid Research

Volumn 56, Issue 1, 2015, Pages 22-37

  Shih, Diana M ^a   Wang, Zeneng ^b   Lee, Richard ^c   Meng, Yonghong ^a   Che, Nam ^a   Charugundla, Sarada ^a   Qi, Hannah ^a   Wu, Judy ^a   Pan, Calvin ^a   Mark Brown, J ^b   Vallim, Thomas ^a   Bennett, Brian J ^d   Graham, Mark ^c   Hazen, Stanley L ^b   Lusis, Aldons J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c ISIS PHARMACEUTICALS   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Insulin; Peroxisome proliferator activated receptor alpha; Trimethylamine N oxide

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; CHOLESTEROL; DIMETHYLANILINE MONOOXYGENASE; FATTY ACID SYNTHASE; FIBROBLAST GROWTH FACTOR 21; FLAVIN CONTAINING MONOOXYGENASE 3; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; INTERLEUKIN 6; INTERMEDIATE DENSITY LIPOPROTEIN; KETONE BODY; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 15; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; LOW DENSITY LIPOPROTEIN; MALATE DEHYDROGENASE (DECARBOXYLATING); MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLCHOLINE; PYRUVATE DEHYDROGENASE KINASE 4; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG; UNESTERIFIED CHOLESTEROL; VERY LOW DENSITY LIPOPROTEIN; DIMETHYLANILINE MONOOXYGENASE (N-OXIDE FORMING); DNA BINDING PROTEIN; KLF15 PROTEIN, MOUSE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; METHYLAMINE; OXYGENASE; TRANSCRIPTION FACTOR; TRIMETHYLAMINE; TRIMETHYLOXAMINE;

ACADL GENE; ALT GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BODY WEIGHT; CONTROLLED STUDY; DISEASE ASSOCIATION; EHHADH GENE; ELOVL6 GENE; FASN GENE; FEMALE; FGF21 GENE; FOXO1 GENE; G6PC GENE; GENE; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID HOMEOSTASIS; LIPID METABOLISM; LIPOGENESIS; MALE; ME GENE; MOUSE; MTTP GENE; NONHUMAN; PDK4 GENE; PEPCK GENE; PGC 1ALPHA GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCD 1 GENE; SIGNAL TRANSDUCTION; SREBP 1C GENE; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMISTRY; DEFICIENCY; ENZYMOLOGY; FECES; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE SILENCING; GENETICS; HOMEOSTASIS; INTESTINE; LIVER; METABOLISM; TUMOR CELL LINE; WESTERN DIET;

ANIMALS; ATHEROSCLEROSIS; BILE ACIDS AND SALTS; CELL LINE, TUMOR; DIET, WESTERN; DNA-BINDING PROTEINS; FECES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; GLUCOSE; HOMEOSTASIS; HUMANS; INSULIN; INTESTINES; LIPID METABOLISM; LIPOGENESIS; LIPOPROTEINS; LIVER; METHYLAMINES; MICE; OXYGENASES; PPAR ALPHA; RECEPTORS, LDL; TRANSCRIPTION FACTORS;

EID: 84920704729     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M051680     Document Type: Article

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