-
2
-
-
0043170900
-
Association of hypoglycemia and cardiac ischemia: A study based on continuous monitoring
-
Desouza, C., Salazar, H., Cheong, B., Murgo, J., and Fonseca, V. (2003) Association of hypoglycemia and cardiac ischemia: a study based on continuous monitoring. Diabetes Care 26, 1485-1489
-
(2003)
Diabetes Care
, vol.26
, pp. 1485-1489
-
-
Desouza, C.1
Salazar, H.2
Cheong, B.3
Murgo, J.4
Fonseca, V.5
-
3
-
-
64349105217
-
Prevention of diabetic retinopathy
-
Einarsdóttir, A. B., and Stefánsson, E. (2009) Prevention of diabetic retinopathy. Lancet 373, 1316-1318
-
(2009)
Lancet
, vol.373
, pp. 1316-1318
-
-
Einarsdóttir, A.B.1
Stefánsson, E.2
-
4
-
-
66749106254
-
Epidemiology and natural history of nonalcoholic fatty liver disease (NAFLD)
-
Bellentani, S., and Marino, M. (2009) Epidemiology and natural history of nonalcoholic fatty liver disease (NAFLD). Ann. Hepatol. 8, S4-S8
-
(2009)
Ann. Hepatol.
, vol.8
-
-
Bellentani, S.1
Marino, M.2
-
5
-
-
0024963282
-
Role of the cyclic AMP-dependent protein kinase in signal transduction
-
Krebs, E. G. (1989) Role of the cyclic AMP-dependent protein kinase in signal transduction. JAMA 262, 1815-1818
-
(1989)
JAMA
, vol.262
, pp. 1815-1818
-
-
Krebs, E.G.1
-
6
-
-
62549108593
-
The evolution of Fox genes and their role in development and disease
-
Hannenhalli, S., and Kaestner, K. H. (2009) The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 10, 233-240
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 233-240
-
-
Hannenhalli, S.1
Kaestner, K.H.2
-
7
-
-
0035185021
-
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
-
Nakae, J., Kitamura, T., Silver, D. L., and Accili, D. (2001) The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J. Clin. Invest. 108, 1359-1367
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1359-1367
-
-
Nakae, J.1
Kitamura, T.2
Silver, D.L.3
Accili, D.4
-
8
-
-
56249100986
-
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
-
Liu, Y., Dentin, R., Chen, D., Hedrick, S., Ravnskjaer, K., Schenk, S., Milne, J., Meyers, D. J., Cole, P., Yates, J., 3rd, Olefsky, J., Guarente, L., and Montminy, M. (2008) A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 456, 269-273
-
(2008)
Nature
, vol.456
, pp. 269-273
-
-
Liu, Y.1
Dentin, R.2
Chen, D.3
Hedrick, S.4
Ravnskjaer, K.5
Schenk, S.6
Milne, J.7
Meyers, D.J.8
Cole, P.9
Yates III, J.10
Olefsky, J.11
Guarente, L.12
Montminy, M.13
-
9
-
-
79251557845
-
Targeting Forkhead box O1 from the concept to metabolic diseases: Lessons from mouse models
-
Cheng, Z., and White, M. F. (2011) Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxid. Redox Signal. 14, 649-661
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 649-661
-
-
Cheng, Z.1
White, M.F.2
-
10
-
-
33846975788
-
Metabolic diapause in pancreatic beta-cells expressing a gain-of-function mutant of the forkhead protein Foxo1
-
Buteau, J., Shlien, A., Foisy, S., and Accili, D. (2007) Metabolic diapause in pancreatic beta-cells expressing a gain-of-function mutant of the forkhead protein Foxo1. J. Biol. Chem. 282, 287-293
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 287-293
-
-
Buteau, J.1
Shlien, A.2
Foisy, S.3
Accili, D.4
-
11
-
-
84874714758
-
Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1-mediated up-regulation of antioxidant enzymes
-
Higuchi, M., Dusting, G. J., Peshavariya, H., Jiang, F., Hsiao, S. T., Chan, E. C., and Liu, G. S. (2013) Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1-mediated up-regulation of antioxidant enzymes. Stem Cells Dev. 22, 878-888
-
(2013)
Stem Cells Dev.
, vol.22
, pp. 878-888
-
-
Higuchi, M.1
Dusting, G.J.2
Peshavariya, H.3
Jiang, F.4
Hsiao, S.T.5
Chan, E.C.6
Liu, G.S.7
-
12
-
-
34249281690
-
Stressing the role of FoxO proteins in lifespan and disease
-
van der Horst, A., and Burgering, B. M. (2007) Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 8, 440-450
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 440-450
-
-
Van Der Horst, A.1
Burgering, B.M.2
-
13
-
-
33846208251
-
Mitogen-activated protein kinases, ERK and p38, phosphorylate and regulate Foxo1
-
Asada, S., Daitoku, H., Matsuzaki, H., Saito, T., Sudo, T., Mukai, H., Iwashita, S., Kako, K., Kishi, T., Kasuya, Y., and Fukamizu, A. (2007) Mitogen-activated protein kinases, ERK and p38, phosphorylate and regulate Foxo1. Cell. Signal. 19, 519-527
-
(2007)
Cell. Signal.
, vol.19
, pp. 519-527
-
-
Asada, S.1
Daitoku, H.2
Matsuzaki, H.3
Saito, T.4
Sudo, T.5
Mukai, H.6
Iwashita, S.7
Kako, K.8
Kishi, T.9
Kasuya, Y.10
Fukamizu, A.11
-
14
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
Daitoku, H., Hatta, M., Matsuzaki, H., Aratani, S., Ohshima, T., Miyagishi, M., Nakajima, T., and Fukamizu, A. (2004) Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc. Natl. Acad. Sci. U.S.A. 101, 10042-10047
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
15
-
-
2342445654
-
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation
-
Fukuoka, M., Daitoku, H., Hatta, M., Matsuzaki, H., Umemura, S., and Fukamizu, A. (2003) Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. Int. J. Mol. Med. 12, 503-508
-
(2003)
Int. J. Mol. Med.
, vol.12
, pp. 503-508
-
-
Fukuoka, M.1
Daitoku, H.2
Hatta, M.3
Matsuzaki, H.4
Umemura, S.5
Fukamizu, A.6
-
16
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1I
-
van der Horst, A., Tertoolen, L. G., de Vries-Smits, L. M., Frye, R. A., Medema, R. H., and Burgering, B. M. (2004) FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1I. J. Biol. Chem. 279, 28873-28879
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28873-28879
-
-
Van Der Horst, A.1
Tertoolen, L.G.2
De Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
17
-
-
77956260966
-
Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization
-
Qiang, L., Banks, A. S., and Accili, D. (2010) Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization. J. Biol. Chem. 285, 27396-27401
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27396-27401
-
-
Qiang, L.1
Banks, A.S.2
Accili, D.3
-
18
-
-
65549136655
-
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB-binding protein
-
He, L., Sabet, A., Djedjos, S., Miller, R., Sun, X., Hussain, M. A., Radovick, S., and Wondisford, F. E. (2009) Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB-binding protein. Cell 137, 635-646
-
(2009)
Cell
, vol.137
, pp. 635-646
-
-
He, L.1
Sabet, A.2
Djedjos, S.3
Miller, R.4
Sun, X.5
Hussain, M.A.6
Radovick, S.7
Wondisford, F.E.8
-
19
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo, S. H., Flechner, L., Qi, L., Zhang, X., Screaton, R. A., Jeffries, S., Hedrick, S., Xu, W., Boussouar, F., Brindle, P., Takemori, H., and Montminy, M. (2005) The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437, 1109-1111
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
Flechner, L.2
Qi, L.3
Zhang, X.4
Screaton, R.A.5
Jeffries, S.6
Hedrick, S.7
Xu, W.8
Boussouar, F.9
Brindle, P.10
Takemori, H.11
Montminy, M.12
-
20
-
-
84866415671
-
Transcriptional co-activator P300 maintains basal hepatic gluconeogenesis
-
He, L., Naik, K., Meng, S., Cao, J., Sidhaye, A. R., Ma, A., Radovick, S., and Wondisford, F. E. (2012) Transcriptional co-activator P300 maintains basal hepatic gluconeogenesis. J. Biol. Chem. 287, 32069-32077
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 32069-32077
-
-
He, L.1
Naik, K.2
Meng, S.3
Cao, J.4
Sidhaye, A.R.5
Ma, A.6
Radovick, S.7
Wondisford, F.E.8
-
21
-
-
0033714888
-
HATs off: Selective synthetic inhibitors of the histone acetyltransferases P300 and PCAF
-
Lau, O. D., Kundu, T. K., Soccio, R. E., Ait-Si-Ali, S., Khalil, E. M., Vassilev, A., Wolffe, A. P., Nakatani, Y., Roeder, R. G., and Cole, P. A. (2000) HATs off: selective synthetic inhibitors of the histone acetyltransferases P300 and PCAF. Mol. Cell 5, 589-595
-
(2000)
Mol. Cell
, vol.5
, pp. 589-595
-
-
Lau, O.D.1
Kundu, T.K.2
Soccio, R.E.3
Ait-Si-Ali, S.4
Khalil, E.M.5
Vassilev, A.6
Wolffe, A.P.7
Nakatani, Y.8
Roeder, R.G.9
Cole, P.A.10
-
22
-
-
77954204335
-
Virtual ligand screening of the P300/CBP histone acetyltransferase: Identification of a selective small molecule inhibitor
-
Bowers, E. M., Yan, G., Mukherjee, C., Orry, A., Wang, L., Holbert, M. A., Crump, N. T., Hazzalin, C. A., Liszczak, G., Yuan, H., Larocca, C., Saldanha, S. A., Abagyan, R., Sun, Y., Meyers, D. J., Marmorstein, R., Mahadevan, L. C., Alani, R. M., and Cole, P. A. (2010) Virtual ligand screening of the P300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem. Biol. 17, 471-482
-
(2010)
Chem. Biol.
, vol.17
, pp. 471-482
-
-
Bowers, E.M.1
Yan, G.2
Mukherjee, C.3
Orry, A.4
Wang, L.5
Holbert, M.A.6
Crump, N.T.7
Hazzalin, C.A.8
Liszczak, G.9
Yuan, H.10
Larocca, C.11
Saldanha, S.A.12
Abagyan, R.13
Sun, Y.14
Meyers, D.J.15
Marmorstein, R.16
Mahadevan, L.C.17
Alani, R.M.18
Cole, P.A.19
-
23
-
-
84880842199
-
Activation of basal gluconeogenesis by co-activator P300 maintains hepatic glycogen storage
-
He, L., Cao, J., Meng, S., Ma, A., Radovick, S., and Wondisford, F. E. (2013) Activation of basal gluconeogenesis by co-activator P300 maintains hepatic glycogen storage. Mol. Endocrinol. 27, 1322-1332
-
(2013)
Mol. Endocrinol.
, vol.27
, pp. 1322-1332
-
-
He, L.1
Cao, J.2
Meng, S.3
Ma, A.4
Radovick, S.5
Wondisford, F.E.6
-
24
-
-
0034234237
-
CBP/P300 in cell growth, transformation, and development
-
Goodman, R. H., and Smolik, S. (2000) CBP/P300 in cell growth, transformation, and development. Genes Dev. 14, 1553-1577
-
(2000)
Genes Dev.
, vol.14
, pp. 1553-1577
-
-
Goodman, R.H.1
Smolik, S.2
-
25
-
-
50849130900
-
Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification
-
Brent, M. M., Anand, R., and Marmorstein, R. (2008) Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure 16, 1407-1416
-
(2008)
Structure
, vol.16
, pp. 1407-1416
-
-
Brent, M.M.1
Anand, R.2
Marmorstein, R.3
-
26
-
-
36749079110
-
Crystal structure of the human FOXO3a-DBD/DNAcomplex suggests the effects of post-translational modification
-
Tsai, K. L., Sun, Y. J., Huang, C. Y., Yang, J. Y., Hung, M. C., and Hsiao, C. D. (2007) Crystal structure of the human FOXO3a-DBD/DNAcomplex suggests the effects of post-translational modification. Nucleic Acids Res. 35, 6984-6994
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 6984-6994
-
-
Tsai, K.L.1
Sun, Y.J.2
Huang, C.Y.3
Yang, J.Y.4
Hung, M.C.5
Hsiao, C.D.6
-
27
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., Hu, L. S., Cheng, H. L., Jedrychowski, M. P., Gygi, S. P., Sinclair, D. A., Alt, F. W., and Greenberg, M. E. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
28
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M., and Guarente, L. (2004) Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
29
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang, Y., Hou, H., Haller, E. M., Nicosia, S. V., and Bai, W. (2005) Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO J. 24, 1021-1032
-
(2005)
EMBO J.
, vol.24
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
30
-
-
23844485211
-
Acetylation of Foxo1 alters its DNA binding ability and sensitivity to phosphorylation
-
Matsuzaki, H., Daitoku, H., Hatta, M., Aoyama, H., Yoshimochi, K., and Fukamizu, A. (2005) Acetylation of Foxo1 alters its DNA binding ability and sensitivity to phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 102, 11278-11283
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 11278-11283
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Aoyama, H.4
Yoshimochi, K.5
Fukamizu, A.6
|