EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia

Molecular Therapy

Volumn 23, Issue 1, 2015, Pages 32-42

  Mitić, Tijana ^a   Caporali, Andrea ^a,b   Floris, Ilaria ^a   Meloni, Marco ^a   Marchetti, Micol ^a   Urrutia, Raul ^c   Angelini, Gianni D ^a,d   Emanueli, Costanza ^a,d  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c MAYO CLINIC   (United States)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEAZANEPLANOCIN; ANGIOGENIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HISTONE H3; LYSINE; MESSENGER RNA; PROTEIN INHIBITOR; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; 3-DEAZANEPLANOCIN; ADENOSINE; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; EZH2 PROTEIN, HUMAN; HISTONE; NOS3 PROTEIN, HUMAN; POLYCOMB REPRESSIVE COMPLEX 2; SMALL INTERFERING RNA;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BDNF GENE; CELL HYPOXIA; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENOS GENE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIMB BLOOD FLOW; LIMB ISCHEMIA; MALE; MOUSE; MUSCLE CELL; MUSCLE ISCHEMIA; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; FEMORAL ARTERY; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; HINDLIMB; ISCHEMIA; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SURGERY; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

MUS;

ADENOSINE; ANIMALS; ANOXIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL HYPOXIA; EPIGENESIS, GENETIC; FEMORAL ARTERY; HINDLIMB; HISTONES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; ISCHEMIA; MALE; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; POLYCOMB REPRESSIVE COMPLEX 2; PRIMARY CELL CULTURE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84920696082     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.163     Document Type: Article

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