메뉴 건너뛰기




Volumn 72, Issue 14, 2012, Pages 3582-3592

Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN B2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR EZH2;

EID: 84863969631     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-2876     Document Type: Article
Times cited : (67)

References (49)
  • 1
    • 77957121811 scopus 로고    scopus 로고
    • Kaposi's sarcoma and its associated herpesvirus
    • Mesri EA, Cesarman E, Boshoff C. Kaposi's sarcoma and its associated herpesvirus. Nat Rev Cancer 2010;10:707-19.
    • (2010) Nat Rev Cancer , vol.10 , pp. 707-719
    • Mesri, E.A.1    Cesarman, E.2    Boshoff, C.3
  • 2
    • 0035024652 scopus 로고    scopus 로고
    • Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: Formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell cultures
    • DOI 10.1128/JVI.75.12.5614-5626.2001
    • Ciufo DM, Cannon JS, Poole LJ, Wu FY, Murray P, Ambinder RF, et al. Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell cultures. J Virol 2001;75:5614-26. (Pubitemid 32488155)
    • (2001) Journal of Virology , vol.75 , Issue.12 , pp. 5614-5626
    • Ciufo, D.M.1    Cannon, J.S.2    Poole, L.J.3    Wu, F.Y.4    Murray, P.5    Ambinder, R.F.6    Hayward, G.S.7
  • 3
    • 0141682147 scopus 로고    scopus 로고
    • Productive lytic replication of a recombinant Kaposi's sarcoma-associated herpesvirus in efficient primary infection of primary human endothelial cells
    • Gao SJ, Deng JH, Zhou FC. Productive lytic replication of a recombinant Kaposi's sarcoma-associated herpesvirus in efficient primary infection of primary human endothelial cells. J Virol 2003;77:9738-49.
    • (2003) J Virol , vol.77 , pp. 9738-9749
    • Gao, S.J.1    Deng, J.H.2    Zhou, F.C.3
  • 6
    • 4544388334 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiation
    • DOI 10.1016/j.virol.2004.07.008, PII S0042682204004799
    • Carroll PA, Brazeau E, Lagunoff M. Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiation. Virology 2004;328:7-18. (Pubitemid 39221907)
    • (2004) Virology , vol.328 , Issue.1 , pp. 7-18
    • Carroll, P.A.1    Brazeau, E.2    Lagunoff, M.3
  • 8
    • 34250811336 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases
    • DOI 10.1128/JVI.00016-07
    • Qian LW, Xie J, Ye F, Gao SJ. Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases. J Virol 2007;81:7001-10. (Pubitemid 46986636)
    • (2007) Journal of Virology , vol.81 , Issue.13 , pp. 7001-7010
    • Qian, L.-W.1    Xie, J.2    Ye, F.3    Gao, S.-J.4
  • 9
    • 56449122995 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin
    • Qian LW, Greene W, Ye F, Gao SJ. Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin. J Virol 2008; 82:11902-12.
    • (2008) J Virol , vol.82 , pp. 11902-11912
    • Qian, L.W.1    Greene, W.2    Ye, F.3    Gao, S.J.4
  • 10
    • 40949131915 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1alpha to induce vascular endothelial growth factor expression
    • DOI 10.1158/0008-5472.CAN-07-2766
    • Shin YC, Joo CH, Gack MU, Lee HR, Jung JU. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression. Cancer Res 2008;68:1751-9. (Pubitemid 351416560)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 1751-1759
    • Shin, Y.C.1    Joo, C.-H.2    Gack, M.U.3    Lee, H.-R.4    Jung, J.U.5
  • 11
    • 47949101732 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells
    • Wang L, Damania B. Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells. Cancer Res 2008;68: 4640-8.
    • (2008) Cancer Res , vol.68 , pp. 4640-4648
    • Wang, L.1    Damania, B.2
  • 12
    • 29744457034 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways
    • DOI 10.1128/JVI.79.24.15027-15037.2005
    • Xie J, Pan H, Yoo S, Gao SJ. Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways. J Virol 2005;79:15027-37. (Pubitemid 43032284)
    • (2005) Journal of Virology , vol.79 , Issue.24 , pp. 15027-15037
    • Xie, J.1    Pan, H.2    Yoo, S.3    Gao, S.-J.4
  • 13
    • 12844264032 scopus 로고    scopus 로고
    • Ephrin B2 expression in Kaposi sarcoma is induced by human herpesvirus type 8: Phenotype switch from venous to arterial endothelium
    • DOI 10.1182/blood-2004-03-0933
    • Masood R, Xia G, Smith DL, Scalia P, Still JG, Tulpule A, et al. Ephrin B2 expression in Kaposi's sarcoma is induced by human herpesvirus type 8: phenotype switch from venous to arterial endothelium. Blood 2005;105:1310-8. (Pubitemid 40170908)
    • (2005) Blood , vol.105 , Issue.3 , pp. 1310-1318
    • Masood, R.1    Xia, G.2    Smith, D.L.3    Scalia, P.4    Still, J.G.5    Tulpule, A.6    Gill, P.S.7
  • 14
    • 38849143913 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: Biological implications
    • DOI 10.1128/JVI.00873-07
    • Sivakumar R, Sharma-Walia N, Raghu H, Veettil MV, Sadagopan S, Bottero V, et al. Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implications. J Virol 2008;82:1759-76. (Pubitemid 351206926)
    • (2008) Journal of Virology , vol.82 , Issue.4 , pp. 1759-1776
    • Sivakumar, R.1    Sharma-Walia, N.2    Raghu, H.3    Veettil, M.V.4    Sadagopan, S.5    Bottero, V.6    Varga, L.7    Levine, R.8    Chandran, B.9
  • 16
    • 77956222562 scopus 로고    scopus 로고
    • Polycomb group proteins: Multi-faceted regulators of somatic stem cells and cancer
    • Sauvageau M, Sauvageau G. Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell 2010;7: 299-313.
    • (2010) Cell Stem Cell , vol.7 , pp. 299-313
    • Sauvageau, M.1    Sauvageau, G.2
  • 18
    • 78651454089 scopus 로고    scopus 로고
    • EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling
    • Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, et al. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling. Cancer Cell 2011;19:86-100.
    • (2011) Cancer Cell , vol.19 , pp. 86-100
    • Chang, C.J.1    Yang, J.Y.2    Xia, W.3    Chen, C.T.4    Xie, X.5    Chao, C.H.6
  • 21
    • 84863165348 scopus 로고    scopus 로고
    • Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
    • McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, et al. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27). Proc Natl Acad Sci U S A 2012;109: 2989-94.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2989-2994
    • McCabe, M.T.1    Graves, A.P.2    Ganji, G.3    Diaz, E.4    Halsey, W.S.5    Jiang, Y.6
  • 23
    • 79960469058 scopus 로고    scopus 로고
    • FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway
    • Kottakis F, Polytarchou C, Foltopoulou P, Sanidas I, Kampranis SC, Tsichlis PN. FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway. Mol Cell 2011;43:285-98.
    • (2011) Mol Cell , vol.43 , pp. 285-298
    • Kottakis, F.1    Polytarchou, C.2    Foltopoulou, P.3    Sanidas, I.4    Kampranis, S.C.5    Tsichlis, P.N.6
  • 24
    • 79957568143 scopus 로고    scopus 로고
    • miR-101 is down-regulated in glioblastoma resulting in EZH2- Induced proliferation, migration, and angiogenesis
    • Smits M, Nilsson J, Mir SE, van der Stoop PM, Hulleman E, Niers JM, et al. miR-101 is down-regulated in glioblastoma resulting in EZH2- induced proliferation, migration, and angiogenesis. Oncotarget 2010; 1:710-20.
    • (2010) Oncotarget , vol.1 , pp. 710-720
    • Smits, M.1    Nilsson, J.2    Mir, S.E.3    Van Der Stoop, P.M.4    Hulleman, E.5    Niers, J.M.6
  • 25
    • 77954688337 scopus 로고    scopus 로고
    • The epigenetic landscape of latent Kaposi's sarcoma-associated herpesvirus genomes
    • Gunther T, Grundhoff A. The epigenetic landscape of latent Kaposi's sarcoma-associated herpesvirus genomes. PLoS Pathog 2010;6: e1000935.
    • (2010) PLoS Pathog , vol.6
    • Gunther, T.1    Grundhoff, A.2
  • 27
    • 1542571327 scopus 로고    scopus 로고
    • Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis
    • DOI 10.1172/JCI200417803
    • Grundhoff A, Ganem D. Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi's sarcoma pathogenesis. J Clin Invest 2004;113:124-36. (Pubitemid 38541639)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.1 , pp. 124-136
    • Grundhoff, A.1    Ganem, D.2
  • 30
    • 45149105263 scopus 로고    scopus 로고
    • Peripheral blood endothelial progenitors as potential reservoirs of Kaposi's sarcoma-associated herpesvirus
    • Della Bella S, Taddeo A, Calabro ML, Brambilla L, Bellinvia M, Bergamo E, et al. Peripheral blood endothelial progenitors as potential reservoirs of Kaposi's sarcoma-associated herpesvirus. PLoS One 2008;3: e1520.
    • (2008) PLoS One , vol.3
    • Della Bella, S.1    Taddeo, A.2    Calabro, M.L.3    Brambilla, L.4    Bellinvia, M.5    Bergamo, E.6
  • 31
    • 79959788025 scopus 로고    scopus 로고
    • Expression and function of EZH2 in synovial fibroblasts: Epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis
    • Trenkmann M, Brock M, Gay RE, Kolling C, Speich R, Michel BA, et al. Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis. Ann Rheum Dis 2011;70:1482-8.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1482-1488
    • Trenkmann, M.1    Brock, M.2    Gay, R.E.3    Kolling, C.4    Speich, R.5    Michel, B.A.6
  • 32
  • 33
    • 3042689762 scopus 로고    scopus 로고
    • Activation of alternative NF-betaB pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1beta-converting enzyme inhibitory protein (vFLIP)
    • DOI 10.1073/pnas.0308016101
    • Matta H, Chaudhary PM. Activation of alternative NF-kappa Bpathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A 2004;101:9399-404. (Pubitemid 38812886)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.25 , pp. 9399-9404
    • Matta, H.1    Chaudhary, P.M.2
  • 34
    • 62749135467 scopus 로고    scopus 로고
    • Asystems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation
    • Konrad A, Wies E, Thurau M, Marquardt G, Naschberger E, Hentschel S, et al. Asystems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation. J Virol 2009;83:2563-74.
    • (2009) J Virol , vol.83 , pp. 2563-2574
    • Konrad, A.1    Wies, E.2    Thurau, M.3    Marquardt, G.4    Naschberger, E.5    Hentschel, S.6
  • 35
    • 84856466661 scopus 로고    scopus 로고
    • The role of EZH2 in tumour progression
    • Chang CJ, Hung MC. The role of EZH2 in tumour progression. Br J Cancer 2012;106:243-7.
    • (2012) Br J Cancer , vol.106 , pp. 243-247
    • Chang, C.J.1    Hung, M.C.2
  • 36
    • 59449103839 scopus 로고    scopus 로고
    • The role of Ephs, Ephrins, and growth factors in Kaposi's sarcoma and implications of EphrinB2 blockade
    • Scehnet JS, Ley EJ, Krasnoperov V, Liu R, Manchanda PK, Sjoberg E, et al. The role of Ephs, Ephrins, and growth factors in Kaposi's sarcoma and implications of EphrinB2 blockade. Blood 2009;113:254-63.
    • (2009) Blood , vol.113 , pp. 254-263
    • Scehnet, J.S.1    Ley, E.J.2    Krasnoperov, V.3    Liu, R.4    Manchanda, P.K.5    Sjoberg, E.6
  • 37
    • 84862777974 scopus 로고    scopus 로고
    • Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis
    • Delgado-Olguin P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, et al. Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet 2012;44:343-7.
    • (2012) Nat Genet , vol.44 , pp. 343-347
    • Delgado-Olguin, P.1    Huang, Y.2    Li, X.3    Christodoulou, D.4    Seidman, C.E.5    Seidman, J.G.6
  • 38
    • 78650062951 scopus 로고    scopus 로고
    • EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
    • Velichutina I, Shaknovich R, Geng H, Johnson NA, Gascoyne RD, Melnick AM, et al. EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis. Blood 2010;116:5247-55.
    • (2010) Blood , vol.116 , pp. 5247-5255
    • Velichutina, I.1    Shaknovich, R.2    Geng, H.3    Johnson, N.A.4    Gascoyne, R.D.5    Melnick, A.M.6
  • 39
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • DOI 10.1093/emboj/cdg542
    • Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J 2003;22:5323-35. (Pubitemid 37279943)
    • (2003) EMBO Journal , vol.22 , Issue.20 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 40
    • 61349112251 scopus 로고    scopus 로고
    • MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
    • Sander S, Bullinger L, Klapproth K, Fiedler K, Kestler HA, Barth TF, et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 2008;112:4202-12.
    • (2008) Blood , vol.112 , pp. 4202-4212
    • Sander, S.1    Bullinger, L.2    Klapproth, K.3    Fiedler, K.4    Kestler, H.A.5    Barth, T.F.6
  • 41
    • 4143054651 scopus 로고    scopus 로고
    • Activated p53 suppresses the histone methyltransferase EZH2 gene
    • DOI 10.1038/sj.onc.1207706
    • Tang X,MilyavskyM, Shats I, Erez N, Goldfinger N, Rotter V. Activated p53 suppresses the histone methyltransferase EZH2 gene. Oncogene 2004;23:5759-69. (Pubitemid 39093021)
    • (2004) Oncogene , vol.23 , Issue.34 , pp. 5759-5769
    • Tang, X.1    Milyavsky, M.2    Shats, I.3    Erez, N.4    Goldfinger, N.5    Rotter, V.6
  • 42
    • 42449106924 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: A novel mechanism of virus control of latency
    • DOI 10.1128/JVI.02370-07
    • Ye FC, Zhou FC, Xie JP, Kang T, Greene W, Kuhne K, et al. Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency. J Virol 2008;82:4235-49. (Pubitemid 351563661)
    • (2008) Journal of Virology , vol.82 , Issue.9 , pp. 4235-4249
    • Ye, F.-C.1    Zhou, F.-C.2    Xie, J.-P.3    Kang, T.4    Greene, W.5    Kuhne, K.6    Lei, X.-F.7    Li, Q.-H.8    Gao, S.-J.9
  • 43
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signalling
    • DOI 10.1038/nrm856
    • Kullander K, Klein R. Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 2002;3:475-86. (Pubitemid 34733429)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.7 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 44
    • 70349569570 scopus 로고    scopus 로고
    • EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures
    • Salvucci O, Maric D, Economopoulou M, Sakakibara S, Merlin S, Follenzi A, et al. EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures. Blood 2009;114: 1707-16.
    • (2009) Blood , vol.114 , pp. 1707-1716
    • Salvucci, O.1    Maric, D.2    Economopoulou, M.3    Sakakibara, S.4    Merlin, S.5    Follenzi, A.6
  • 47
    • 79957912993 scopus 로고    scopus 로고
    • EZH2- mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis
    • Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, Feng H, et al. EZH2- mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. Cancer Res 2011;71: 4028-39.
    • (2011) Cancer Res , vol.71 , pp. 4028-4039
    • Cheng, A.S.1    Lau, S.S.2    Chen, Y.3    Kondo, Y.4    Li, M.S.5    Feng, H.6
  • 48
    • 77951045228 scopus 로고    scopus 로고
    • Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML
    • Paul TA, Bies J, Small D, Wolff L. Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML. Blood 2010;115:3098-108.
    • (2010) Blood , vol.115 , pp. 3098-3108
    • Paul, T.A.1    Bies, J.2    Small, D.3    Wolff, L.4
  • 49
    • 80052222327 scopus 로고    scopus 로고
    • Context-specific regulation of NF-kappaB target gene expression by EZH2 in breast cancers
    • Lee ST, Li Z, Wu Z, Aau M, Guan P, Karuturi RK, et al. Context-specific regulation of NF-kappaB target gene expression by EZH2 in breast cancers. Mol Cell 2011;43:798-810.
    • (2011) Mol Cell , vol.43 , pp. 798-810
    • Lee, S.T.1    Li, Z.2    Wu, Z.3    Aau, M.4    Guan, P.5    Karuturi, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.