Free-energy landscape of ion-channel voltage-sensor-domain activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 1, 2015, Pages 124-129

  Delemotte, Lucie ^a   Kasimova, Marina A ^b,c   Klein, Michael L ^a   Tarek, Mounir ^b,d   Carnevale, Vincenzo ^a  

^a Temple University   (United States)

^b UNIVERSITÉ DE LORRAINE   (France)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

^d CNRS   (France)

Author keywords

Electrophysiology; Gating kinetics; Kv1.2; Metadynamics; Voltage gated ion channels

Indexed keywords

ION CHANNEL; POTASSIUM CHANNEL KV1.2;

ARTICLE; DYNAMICS; ELECTRIC POTENTIAL; ENERGY; GENE MUTATION; LANDSCAPE; MICROSCOPY; MODULATION; PHENOMENOLOGY; SENSOR; BIOLOGICAL MODEL; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

ION CHANNEL GATING; KV1.2 POTASSIUM CHANNEL; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84920447262     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1416959112     Document Type: Article

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