Biologically inactive leptin and early-onset extreme obesity

New England Journal of Medicine

Volumn 372, Issue 1, 2015, Pages 48-54

  Wabitsch, Martin ^a   Funcke, Jan Bernd ^a   Lennerz, Belinda ^a   Kuhnle Krahl, Ursula ^c   Lahr, Georgia ^b   Debatin, Klaus Michael ^b   Vatter, Petra ^a   Gierschik, Peter ^a   Moepps, Barbara ^a   Fischer Posovszky, Pamela ^a  

^a UNIVERSITY OF ULM   (Germany)

^b Department of Pediatrics and Adolescent Medicine ^*  (Germany)

^c Endokrinologische Schwerpunktpraxis für Kinder und Jugendliche   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FOLLITROPIN; GENOMIC DNA; LEPTIN; LUTEINIZING HORMONE; METRELEPTIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; LEPTIN RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY HEIGHT; BODY WEIGHT; CASE REPORT; CHILD; CHILDHOOD OBESITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DNA SEQUENCE; EAR INFECTION; FEEDING BEHAVIOR; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HYPERPHAGIA; LEP GENE; LEPTIN DEFICIENCY; LUNG INFECTION; LYMPHOCYTE COUNT; MALE; MOUSE; MUTAGENESIS; NONHUMAN; PRESCHOOL CHILD; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RECURRENT DISEASE; REVIEW; SCHOOL CHILD; ANALOGS AND DERIVATIVES; ANIMAL; BODY MASS; CELL CULTURE; DEFICIENCY; DRUG EFFECTS; GENETICS; INBRED MOUSE STRAIN; METABOLISM; MUTATION; OBESITY; ONSET AGE;

AGE OF ONSET; ANIMALS; BODY MASS INDEX; CELLS, CULTURED; CHILD, PRESCHOOL; FEEDING BEHAVIOR; FEMALE; HUMANS; LEPTIN; MALE; MICE; MICE, INBRED STRAINS; MUTATION; OBESITY; RECEPTORS, LEPTIN; SEQUENCE ANALYSIS, DNA;

EID: 84920413856     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1406653     Document Type: Article

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