메뉴 건너뛰기




Volumn 7, Issue 1, 2015, Pages 102-113

Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic complications, obesity risk and hypertension in the Tunisian population

Author keywords

CDKAL1; Genetic association; IGF2BP2; Tunisian population; Type 2 diabetes

Indexed keywords

BINDING PROTEIN; INSULIN LIKE GROWTH FACTOR 2 MRNA BINDING PROTEIN 2; MESSENGER RNA; SOMATOMEDIN B; UNCLASSIFIED DRUG; CDKAL1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE 5; IGF2BP2 PROTEIN, HUMAN; RNA BINDING PROTEIN;

EID: 84920136626     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/1753-0407.12147     Document Type: Article
Times cited : (28)

References (48)
  • 1
    • 0032449219 scopus 로고    scopus 로고
    • The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity
    • Gerich JE. The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity. Endocr Rev. 1998; 19: 491-503.
    • (1998) Endocr Rev , vol.19 , pp. 491-503
    • Gerich, J.E.1
  • 2
    • 33748997922 scopus 로고    scopus 로고
    • Type-2 diabetes: A cocktail of genetic discovery
    • Spec No 2: R202-R209
    • Freeman H, Cox RD. Type-2 diabetes: A cocktail of genetic discovery. Hum Mol Genet. 2006; 15 Spec No 2: R202-209.
    • (2006) Hum Mol Genet , vol.15
    • Freeman, H.1    Cox, R.D.2
  • 4
    • 33847007664 scopus 로고    scopus 로고
    • The global diabetes pandemic: The Tunisian experience
    • Bouguerra R, Alberti H, Salem LB etal. The global diabetes pandemic: The Tunisian experience. Eur J Clin Nutr. 2007; 61: 160-165.
    • (2007) Eur J Clin Nutr , vol.61 , pp. 160-165
    • Bouguerra, R.1    Alberti, H.2    Salem, L.B.3
  • 5
    • 0028122011 scopus 로고
    • A brain-specific activator of cyclin-dependent kinase 5
    • Lew J, Huang QQ, Qi Z etal. A brain-specific activator of cyclin-dependent kinase 5. Nature. 1994; 371: 423-426.
    • (1994) Nature , vol.371 , pp. 423-426
    • Lew, J.1    Huang, Q.Q.2    Qi, Z.3
  • 6
    • 27144441483 scopus 로고    scopus 로고
    • Cdk5-dependent regulation of glucose-stimulated insulin secretion
    • Wei FY, Nagashima K, Ohshima T etal. Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat Med. 2005; 11: 1104-1108.
    • (2005) Nat Med , vol.11 , pp. 1104-1108
    • Wei, F.Y.1    Nagashima, K.2    Ohshima, T.3
  • 7
    • 84855262907 scopus 로고    scopus 로고
    • Cyclin-Dependent Kinase 5/p35/p39: A novel and imminent therapeutic target for diabetes mellitus
    • Ahmed D, Sharma M. Cyclin-Dependent Kinase 5/p35/p39: A novel and imminent therapeutic target for diabetes mellitus. Int J Endocrinol. 2011; 2011: 530274.
    • (2011) Int J Endocrinol , vol.2011 , pp. 530274
    • Ahmed, D.1    Sharma, M.2
  • 8
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E, Weedon MN, Lindgren CM etal. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science. 2007; 316: 1336-1341.
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3
  • 9
    • 34249828965 scopus 로고    scopus 로고
    • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
    • Steinthorsdottir V, Thorleifsson G, Reynisdottir I etal. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet. 2007; 39: 770-775.
    • (2007) Nat Genet , vol.39 , pp. 770-775
    • Steinthorsdottir, V.1    Thorleifsson, G.2    Reynisdottir, I.3
  • 10
    • 6044250156 scopus 로고    scopus 로고
    • Increased expression of IGF II mRNA-binding protein 1 mRNA is associated with an advanced clinical stage and poor prognosis in patients with ovarian cancer
    • Gu L, Shigemasa K, Ohama K. Increased expression of IGF II mRNA-binding protein 1 mRNA is associated with an advanced clinical stage and poor prognosis in patients with ovarian cancer. Int J Oncol. 2004; 24: 671-678.
    • (2004) Int J Oncol , vol.24 , pp. 671-678
    • Gu, L.1    Shigemasa, K.2    Ohama, K.3
  • 11
    • 36849011549 scopus 로고    scopus 로고
    • Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: Validation and extension of genome-wide association studies
    • Grarup N, Rose CS, Andersson EA etal. Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10, 705 Danish subjects: Validation and extension of genome-wide association studies. Diabetes. 2007; 56: 3105-3111.
    • (2007) Diabetes , vol.56 , pp. 3105-3111
    • Grarup, N.1    Rose, C.S.2    Andersson, E.A.3
  • 12
    • 49249094275 scopus 로고    scopus 로고
    • Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps
    • Groenewoud MJ, Dekker JM, Fritsche A etal. Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps. Diabetologia. 2008; 51: 1659-1663.
    • (2008) Diabetologia , vol.51 , pp. 1659-1663
    • Groenewoud, M.J.1    Dekker, J.M.2    Fritsche, A.3
  • 13
    • 42449159284 scopus 로고    scopus 로고
    • Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study
    • Palmer ND, Goodarzi MO, Langefeld CD etal. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2008; 57: 1093-1100.
    • (2008) Diabetes , vol.57 , pp. 1093-1100
    • Palmer, N.D.1    Goodarzi, M.O.2    Langefeld, C.D.3
  • 14
    • 77955468123 scopus 로고    scopus 로고
    • IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes
    • Rodriguez S, Eiriksdottir G, Gaunt TR etal. IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes. Growth Horm IGF Res. 2010; 20: 310-318.
    • (2010) Growth Horm IGF Res , vol.20 , pp. 310-318
    • Rodriguez, S.1    Eiriksdottir, G.2    Gaunt, T.R.3
  • 15
    • 70449657762 scopus 로고    scopus 로고
    • IGF2 mRNA-binding protein 2: Biological function and putative role in type 2 diabetes
    • Christiansen J, Kolte AM, Hansen T, Nielsen FC. IGF2 mRNA-binding protein 2: Biological function and putative role in type 2 diabetes. J Mol Endocrinol. 2009; 43: 187-195.
    • (2009) J Mol Endocrinol , vol.43 , pp. 187-195
    • Christiansen, J.1    Kolte, A.M.2    Hansen, T.3    Nielsen, F.C.4
  • 16
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R, Voight BF, Lyssenko V etal. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007; 316: 1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3
  • 17
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott LJ, Mohlke KL, Bonnycastle LL etal. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science. 2007; 316: 1341-1345.
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3
  • 18
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998; 15: 539-553.
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 19
    • 0025845943 scopus 로고
    • Grading diabetic retinopathy from stereoscopic color fundus photographs-an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group. Grading diabetic retinopathy from stereoscopic color fundus photographs-an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology. 1991; 98 (Suppl. 5): 786-806.
    • (1991) Ophthalmology , vol.98 , Issue.5 SUPPL , pp. 786-806
  • 20
    • 34249111588 scopus 로고    scopus 로고
    • Familial aggregation and excess maternal transmission of type 2 diabetes in Tunisia
    • Arfa I, Abid A, Malouche D etal. Familial aggregation and excess maternal transmission of type 2 diabetes in Tunisia. Postgrad Med J. 2007; 83: 348-351.
    • (2007) Postgrad Med J , vol.83 , pp. 348-351
    • Arfa, I.1    Abid, A.2    Malouche, D.3
  • 21
    • 42249085432 scopus 로고    scopus 로고
    • Lack of association between the angiotensin-converting enzyme gene (I/D) polymorphism and diabetic nephropathy in Tunisian type 2 diabetic patients
    • Arfa I, Abid A, Nouira S etal. Lack of association between the angiotensin-converting enzyme gene (I/D) polymorphism and diabetic nephropathy in Tunisian type 2 diabetic patients. J Renin Angiotensin Aldosterone Syst. 2008; 9: 32-36.
    • (2008) J Renin Angiotensin Aldosterone Syst , vol.9 , pp. 32-36
    • Arfa, I.1    Abid, A.2    Nouira, S.3
  • 22
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 23
  • 24
    • 0025215247 scopus 로고
    • Power and sample size calculations. A review and computer program
    • Dupont WD, Plummer WD Jr. Power and sample size calculations. A review and computer program. Control Clin Trials. 1990; 11: 116-128.
    • (1990) Control Clin Trials , vol.11 , pp. 116-128
    • Dupont, W.D.1    Plummer Jr, W.D.2
  • 25
    • 70249146533 scopus 로고    scopus 로고
    • Underlying genetic models of inheritance in established type 2 diabetes associations
    • Salanti G, Southam L, Altshuler D etal. Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol. 2009; 170: 537-545.
    • (2009) Am J Epidemiol , vol.170 , pp. 537-545
    • Salanti, G.1    Southam, L.2    Altshuler, D.3
  • 26
    • 47749128415 scopus 로고    scopus 로고
    • Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
    • Sanghera DK, Ortega L, Han S etal. Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Med Genet. 2008; 9: 59.
    • (2008) BMC Med Genet , vol.9 , pp. 59
    • Sanghera, D.K.1    Ortega, L.2    Han, S.3
  • 27
    • 43049149732 scopus 로고    scopus 로고
    • Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
    • Hertel JK, Johansson S, Raeder H etal. Genetic analysis of recently identified type 2 diabetes loci in 1, 638 unselected patients with type 2 diabetes and 1, 858 control participants from a Norwegian population-based cohort (the HUNT study). Diabetologia. 2008; 51: 971-977.
    • (2008) Diabetologia , vol.51 , pp. 971-977
    • Hertel, J.K.1    Johansson, S.2    Raeder, H.3
  • 28
    • 56349170898 scopus 로고    scopus 로고
    • Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
    • Wu Y, Li H, Loos RJ etal. Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes. 2008; 57: 2834-2842.
    • (2008) Diabetes , vol.57 , pp. 2834-2842
    • Wu, Y.1    Li, H.2    Loos, R.J.3
  • 29
    • 50449104632 scopus 로고    scopus 로고
    • Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
    • Ng MC, Park KS, Oh B etal. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6, 719 Asians. Diabetes. 2008; 57: 2226-2233.
    • (2008) Diabetes , vol.57 , pp. 2226-2233
    • Ng, M.C.1    Park, K.S.2    Oh, B.3
  • 30
    • 63249107785 scopus 로고    scopus 로고
    • Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians
    • Rong R, Hanson RL, Ortiz D etal. Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians. Diabetes. 2009; 58: 478-488.
    • (2009) Diabetes , vol.58 , pp. 478-488
    • Rong, R.1    Hanson, R.L.2    Ortiz, D.3
  • 31
    • 84860538298 scopus 로고    scopus 로고
    • Strong association of common variants in the IGF2BP2 gene with type 2 diabetes in Lebanese Arabs
    • Nemr R, Echtay A, Dashti EA etal. Strong association of common variants in the IGF2BP2 gene with type 2 diabetes in Lebanese Arabs. Diabetes Res Clin Pract. 2012; 96: 225-229.
    • (2012) Diabetes Res Clin Pract , vol.96 , pp. 225-229
    • Nemr, R.1    Echtay, A.2    Dashti, E.A.3
  • 32
    • 47749124258 scopus 로고    scopus 로고
    • Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value
    • Cauchi S, Meyre D, Durand E etal. Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS ONE. 2008; 3: e2031.
    • (2008) PLoS ONE , vol.3
    • Cauchi, S.1    Meyre, D.2    Durand, E.3
  • 33
    • 84869144898 scopus 로고    scopus 로고
    • Contribution of common variants of ENPP1, IGF2BP2, KCNJ11, MLXIPL, PPARgamma, SLC30A8 and TCF7L2 to the risk of type 2 diabetes in Lebanese and Tunisian Arabs
    • Mtiraoui N, Turki A, Nemr R etal. Contribution of common variants of ENPP1, IGF2BP2, KCNJ11, MLXIPL, PPARgamma, SLC30A8 and TCF7L2 to the risk of type 2 diabetes in Lebanese and Tunisian Arabs. Diabetes Metab. 2012; 38: 444-449.
    • (2012) Diabetes Metab , vol.38 , pp. 444-449
    • Mtiraoui, N.1    Turki, A.2    Nemr, R.3
  • 34
    • 84866755863 scopus 로고    scopus 로고
    • European genetic variants associated with type 2 diabetes in North African Arabs
    • Cauchi S, Ezzidi I, El Achhab Y etal. European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes Metab. 2012; 38: 316-323.
    • (2012) Diabetes Metab , vol.38 , pp. 316-323
    • Cauchi, S.1    Ezzidi, I.2    El Achhab, Y.3
  • 35
    • 84865862203 scopus 로고    scopus 로고
    • IGF2BP2 and IGF2 genetic effects in diabetes and diabetic nephropathy
    • Gu T, Horova E, Mollsten A etal. IGF2BP2 and IGF2 genetic effects in diabetes and diabetic nephropathy. J Diabetes Complications. 2012; 26: 393-398.
    • (2012) J Diabetes Complications , vol.26 , pp. 393-398
    • Gu, T.1    Horova, E.2    Mollsten, A.3
  • 36
    • 63049114182 scopus 로고    scopus 로고
    • Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans
    • Li X, Allayee H, Xiang AH etal. Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity (Silver Spring). 2009; 17: 729-736.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 729-736
    • Li, X.1    Allayee, H.2    Xiang, A.H.3
  • 37
    • 55649107932 scopus 로고    scopus 로고
    • The search for putative unifying genetic factors for components of the metabolic syndrome
    • Sjogren M, Lyssenko V, Jonsson A etal. The search for putative unifying genetic factors for components of the metabolic syndrome. Diabetologia. 2008; 51: 2242-2251.
    • (2008) Diabetologia , vol.51 , pp. 2242-2251
    • Sjogren, M.1    Lyssenko, V.2    Jonsson, A.3
  • 38
    • 77957563698 scopus 로고    scopus 로고
    • The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI
    • Webster RJ, Warrington NM, Beilby JP, Frayling TM, Palmer LJ. The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI. BMC Med Genet. 2010; 11: 140.
    • (2010) BMC Med Genet , vol.11 , pp. 140
    • Webster, R.J.1    Warrington, N.M.2    Beilby, J.P.3    Frayling, T.M.4    Palmer, L.J.5
  • 39
    • 84881282853 scopus 로고    scopus 로고
    • The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility
    • Chistiakov DA, Nikitin AG, Smetanina SA etal. The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility. Rev Diabet Stud. 2012; 9: 112-122.
    • (2012) Rev Diabet Stud , vol.9 , pp. 112-122
    • Chistiakov, D.A.1    Nikitin, A.G.2    Smetanina, S.A.3
  • 40
    • 84877038260 scopus 로고    scopus 로고
    • Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population
    • Chen G, Xu Y, Lin Y etal. Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population. J Diabetes. 2013; 5: 136-145.
    • (2013) J Diabetes , vol.5 , pp. 136-145
    • Chen, G.1    Xu, Y.2    Lin, Y.3
  • 41
    • 53549096229 scopus 로고    scopus 로고
    • Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals
    • Liu Y, Yu L, Zhang D etal. Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals. Diabetologia. 2008; 51: 2134-2137.
    • (2008) Diabetologia , vol.51 , pp. 2134-2137
    • Liu, Y.1    Yu, L.2    Zhang, D.3
  • 42
    • 35848945259 scopus 로고    scopus 로고
    • Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population
    • Horikoshi M, Hara K, Ito C etal. Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia. 2007; 50: 2461-2466.
    • (2007) Diabetologia , vol.50 , pp. 2461-2466
    • Horikoshi, M.1    Hara, K.2    Ito, C.3
  • 43
    • 40949087723 scopus 로고    scopus 로고
    • Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
    • Omori S, Tanaka Y, Takahashi A etal. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes. 2008; 57: 791-795.
    • (2008) Diabetes , vol.57 , pp. 791-795
    • Omori, S.1    Tanaka, Y.2    Takahashi, A.3
  • 44
    • 49249104932 scopus 로고    scopus 로고
    • Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan
    • Horikawa Y, Miyake K, Yasuda K etal. Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. J Clin Endocrinol Metab. 2008; 93: 3136-3141.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3136-3141
    • Horikawa, Y.1    Miyake, K.2    Yasuda, K.3
  • 45
    • 63249118012 scopus 로고    scopus 로고
    • Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening
    • Tabara Y, Osawa H, Kawamoto R etal. Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes. 2009; 58: 493-498.
    • (2009) Diabetes , vol.58 , pp. 493-498
    • Tabara, Y.1    Osawa, H.2    Kawamoto, R.3
  • 46
    • 77954447364 scopus 로고    scopus 로고
    • CDKAL1 and type 2 diabetes: A global meta-analysis
    • Dehwah MA, Wang M, Huang QY. CDKAL1 and type 2 diabetes: A global meta-analysis. Genet Mol Res. 2010; 9: 1109-1120.
    • (2010) Genet Mol Res , vol.9 , pp. 1109-1120
    • Dehwah, M.A.1    Wang, M.2    Huang, Q.Y.3
  • 47
    • 84856349504 scopus 로고    scopus 로고
    • Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population
    • Nemr R, Almawi AW, Echtay A, Sater MS, Daher HS, Almawi WY. Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population. Diabetes Res Clin Pract. 2012; 95: e37-e40.
    • (2012) Diabetes Res Clin Pract , vol.95 , pp. e37-e40
    • Nemr, R.1    Almawi, A.W.2    Echtay, A.3    Sater, M.S.4    Daher, H.S.5    Almawi, W.Y.6
  • 48
    • 84860269904 scopus 로고    scopus 로고
    • [Association analysis of genetic polymorphisms of TCF7L2, CDKAL1, SLC30A8, HHEX genes and microvascular complications of type 2 diabetes mellitus]
    • Fu LL, Lin Y, Yang ZL, Yin YB. [Association analysis of genetic polymorphisms of TCF7L2, CDKAL1, SLC30A8, HHEX genes and microvascular complications of type 2 diabetes mellitus]. Chin J Med Genet. 2012; 29: 194-199.
    • (2012) Chin J Med Genet , vol.29 , pp. 194-199
    • Fu, L.L.1    Lin, Y.2    Yang, Z.L.3    Yin, Y.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.