-
1
-
-
77954941113
-
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR 3 by Cdk5
-
Choi J. H., Banks A. S., Estall J. L., Kajimura S., Bostrm P., Laznik D., Ruas J. L., Chalmers M. J., Kamenecka T. M., Blher M., Griffin P. R., Spiegelman B. M., Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR 3 by Cdk5 Nature 2010 466 7305 451 456
-
(2010)
Nature
, vol.466
, Issue.7305
, pp. 451-456
-
-
Choi, J.H.1
Banks, A.S.2
Estall, J.L.3
Kajimura, S.4
Bostrm, P.5
Laznik, D.6
Ruas, J.L.7
Chalmers, M.J.8
Kamenecka, T.M.9
Blher, M.10
Griffin, P.R.11
Spiegelman, B.M.12
-
2
-
-
0031466305
-
Cyclin-dependent kinases: Engines, clocks, and microprocessors
-
DOI 10.1146/annurev.cellbio.13.1.261
-
Morgan D. O., Cyclin-dependent kinases: engines, clocks, and microprocessors Annual Review of Cell and Developmental Biology 1997 13 261 291 (Pubitemid 28034527)
-
(1997)
Annual Review of Cell and Developmental Biology
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
3
-
-
0028122011
-
A brain-specific activator of cyclin-dependent kinase 5
-
DOI 10.1038/371423a0
-
Lew J., Huang Q. Q., Qi Z., Winkfein R. J., Aebersold R., Hunt T., Wang J. H., A brain-specific activator of cyclin-dependent kinase 5 Nature 1994 371 6496 423 426 (Pubitemid 24302557)
-
(1994)
Nature
, vol.371
, Issue.6496
, pp. 423-426
-
-
Lew, J.1
Huang, Q.-Q.2
Qi, Z.3
Winkfein, R.J.4
Aebersold, R.5
Hunt, T.6
Wang, J.H.7
-
4
-
-
0027978170
-
P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
-
DOI 10.1038/371419a0
-
Tsai L. H., Delalle I., Caviness V. S., Chae T., Harlow E., p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 Nature 1994 371 6496 419 423 (Pubitemid 24302556)
-
(1994)
Nature
, vol.371
, Issue.6496
, pp. 419-423
-
-
Teai, L.-H.1
Delalle, I.2
Cavness Jr., V.S.3
Chae, T.4
Harlow, E.5
-
5
-
-
0028858467
-
An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator
-
Tang D., Yeung J., Lee K. Y., Matsushita M., Matsui H., Tomizawa K., Hatase O., Wang J. H., An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator Journal of Biological Chemistry 1995 270 45 26897 26903
-
(1995)
Journal of Biological Chemistry
, vol.270
, Issue.45
, pp. 26897-26903
-
-
Tang, D.1
Yeung, J.2
Lee, K.Y.3
Matsushita, M.4
Matsui, H.5
Tomizawa, K.6
Hatase, O.7
Wang, J.H.8
-
6
-
-
0027425599
-
Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
-
Tsai L. H., Takahashi T., Caviness V. S., Harlow E., Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system Development 1993 119 4 1029 1040 (Pubitemid 23358574)
-
(1993)
Development
, vol.119
, Issue.4
, pp. 1029-1040
-
-
Tsai, L.-H.1
Takahashi, T.2
Caviness Jr., V.S.3
Harlow, E.4
-
7
-
-
2542461194
-
Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic β-cells
-
DOI 10.1210/en.2003-1522
-
Ubeda M., Kemp D. M., Habener J. F., Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic -cells Endocrinology 2004 145 6 3023 3031 (Pubitemid 38686252)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 3023-3031
-
-
Ubeda, M.1
Kemp, D.M.2
Habener, J.F.3
-
8
-
-
3142660506
-
2+-dependent exocytosis
-
DOI 10.1074/jbc.M312711200
-
Lilja L., Johansson J. U., Gromada J., Mandic S. A., Fried G., Berggren P. O., Bark C., Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca 2+ -dependent exocytosis Journal of Biological Chemistry 2004 279 28 29534 29541 (Pubitemid 38915834)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29534-29541
-
-
Lilja, L.1
Johansson, J.U.2
Gromada, J.3
Mandic, S.A.4
Fried, G.5
Berggren, P.-O.6
Bark, C.7
-
9
-
-
27144441483
-
Cdk5-dependent regulation of glucose-stimulated insulin secretion
-
DOI 10.1038/nm1299, PII N1299
-
Wei F. Y., Nagashima K., Ohshima T., Saheki Y., Lu Y. F., Matsushita M., Yamada Y., Mikoshiba K., Seino Y., Matsui H., Tomizawa K., Cdk5-dependent regulation of glucose-stimulated insulin secretion Nature Medicine 2005 11 10 1104 1108 (Pubitemid 41486833)
-
(2005)
Nature Medicine
, vol.11
, Issue.10
, pp. 1104-1108
-
-
Wei, F.-Y.1
Nagashima, K.2
Ohshima, T.3
Saheki, Y.4
Lu, Y.-F.5
Matsushita, M.6
Yamada, Y.7
Mikoshiba, K.8
Seino, Y.9
Matsui, H.10
Tomizawa, K.11
-
10
-
-
0033769693
-
CAMP-GEFII is a direct target of cAMP in regulated exocytosis
-
Ozaki N., Shibasaki T., Kashima Y., Miki T., Takahashi K., Ueno H., Sunaga Y., Yano H., Matsuura Y., Iwanaga T., Takai Y., Seino S., cAMP-GEFII is a direct target of cAMP in regulated exocytosis Nature Cell Biology 2000 2 11 805 811
-
(2000)
Nature Cell Biology
, vol.2
, Issue.11
, pp. 805-811
-
-
Ozaki, N.1
Shibasaki, T.2
Kashima, Y.3
Miki, T.4
Takahashi, K.5
Ueno, H.6
Sunaga, Y.7
Yano, H.8
Matsuura, Y.9
Iwanaga, T.10
Takai, Y.11
Seino, S.12
-
11
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey P. D., Russo A. A., Polyak K., Gibbs E., Hurwitz J., Massague J., Pavletich N. P., Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex Nature 1995 376 6538 313 320
-
(1995)
Nature
, vol.376
, Issue.6538
, pp. 313-320
-
-
Jeffrey, P.D.1
Russo, A.A.2
Polyak, K.3
Gibbs, E.4
Hurwitz, J.5
Massague, J.6
Pavletich, N.P.7
-
12
-
-
0029767016
-
Structural basis of cyclin-dependent kinase activation by phosphorylation
-
DOI 10.1038/nsb0896-696
-
Russo A. A., Jeffrey P. D., Pavletich N. P., Structural basis of cyclin-dependent kinase activation by phosphorylation Nature Structural Biology 1996 3 8 696 700 (Pubitemid 26260060)
-
(1996)
Nature Structural Biology
, vol.3
, Issue.8
, pp. 696-700
-
-
Russo, A.A.1
Jeffrey, P.D.2
Pavletich, N.P.3
-
13
-
-
0033710860
-
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth
-
Zukerberg L. R., Patrick G. N., Nikolic M., Humbert S., Wu C. L., Lanier L. M., Gertler F. B., Vidal M., van Etten R. A., Tsai L. H., Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth Neuron 2000 26 3 633 646
-
(2000)
Neuron
, vol.26
, Issue.3
, pp. 633-646
-
-
Zukerberg, L.R.1
Patrick, G.N.2
Nikolic, M.3
Humbert, S.4
Wu, C.L.5
Lanier, L.M.6
Gertler, F.B.7
Vidal, M.8
Van Etten, R.A.9
Tsai, L.H.10
-
14
-
-
0029880475
-
Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus
-
DOI 10.1074/jbc.271.10.5443
-
Matsuura I., Wang J. H., Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus Journal of Biological Chemistry 1996 271 10 5443 5450 (Pubitemid 26083877)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.10
, pp. 5443-5450
-
-
Matsuura, I.1
Wang, J.H.2
-
15
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler A. E., Janson J., Bonner-Weir S., Ritzel R., Rizza R. A., Butler P. C., -cell deficit and increased -cell apoptosis in humans with type 2 diabetes Diabetes 2003 52 1 102 110 (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
16
-
-
76149102617
-
Evidence for proteotoxicity in cells in type 2 diabetes: Toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway
-
Gurlo T., Ryazantsev S., Huang C. J., Yeh M. W., Reber H. A., Hines O. J., O'Brien T. D., Glabe C. G., Butler P. C., Evidence for proteotoxicity in cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway American Journal of Pathology 2010 176 2 861 869
-
(2010)
American Journal of Pathology
, vol.176
, Issue.2
, pp. 861-869
-
-
Gurlo, T.1
Ryazantsev, S.2
Huang, C.J.3
Yeh, M.W.4
Reber, H.A.5
Hines, O.J.6
O'Brien, T.D.7
Glabe, C.G.8
Butler, P.C.9
-
17
-
-
10644225416
-
Protein misfolding and aggregation: New examples in medicine and biology of the dark side of the protein world
-
DOI 10.1016/j.bbadis.2004.08.004, PII S092544390400136X, The Biology and Pathobiology of Tau
-
Stefani M., Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world Biochimica et Biophysica Acta 2004 1739 1 5 25 (Pubitemid 39647706)
-
(2004)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.1
, pp. 5-25
-
-
Stefani, M.1
-
18
-
-
0029086781
-
The reduction of insulin gene transcription in HIT-T15 cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression
-
Sharma A., Olson L. K., Robertson R. P., Stein R., The reduction of insulin gene transcription in HIT-T15 cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression Molecular Endocrinology 1995 9 9 1127 1134
-
(1995)
Molecular Endocrinology
, vol.9
, Issue.9
, pp. 1127-1134
-
-
Sharma, A.1
Olson, L.K.2
Robertson, R.P.3
Stein, R.4
-
19
-
-
0029073426
-
Reduction of insulin gene transcription in HIT-T15 cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression
-
Olson L. K., Sharma A., Peshavaria M., Wright C. V. E., Towle H. C., Robertson R. P., Stein R., Reduction of insulin gene transcription in HIT-T15 cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression Proceedings of the National Academy of Sciences of the United States of America 1995 92 20 9127 9131
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.20
, pp. 9127-9131
-
-
Olson, L.K.1
Sharma, A.2
Peshavaria, M.3
Wright, C.V.E.4
Towle, H.C.5
Robertson, R.P.6
Stein, R.7
-
20
-
-
0022522943
-
Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions
-
Leahy J. L., Cooper H. E., Deal D. A., Weir G. C., Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions Journal of Clinical Investigation 1986 77 3 908 915 (Pubitemid 16067964)
-
(1986)
Journal of Clinical Investigation
, vol.77
, Issue.3
, pp. 908-915
-
-
Leahy, J.L.1
Cooper, H.E.2
Deal, D.A.3
Weir, G.C.4
-
21
-
-
10744227975
-
2-terminal Kinase
-
DOI 10.2337/diabetes.52.12.2896
-
Kawamori D., Kajimoto Y., Kaneto H., Umayahara Y., Fujitani Y., Miyatsuka T., Watada H., Leibiger I. B., Yamasaki Y., Hori M., Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH 2 -terminal kinase Diabetes 2003 52 12 2896 2904 (Pubitemid 37466858)
-
(2003)
Diabetes
, vol.52
, Issue.12
, pp. 2896-2904
-
-
Kawamori, D.1
Kajimoto, Y.2
Kaneto, H.3
Umayahara, Y.4
Fujitani, Y.5
Miyatsuka, T.6
Watada, H.7
Leibiger, I.B.8
Yamasaki, Y.9
Hori, M.10
-
22
-
-
33749389928
-
Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity
-
DOI 10.1074/jbc.M604690200
-
Ubeda M., Rukstalis J. M., Habener J. F., Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity Journal of Biological Chemistry 2006 281 39 28858 28864 (Pubitemid 44507029)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.39
, pp. 28858-28864
-
-
Ubeda, M.1
Rukstalis, J.M.2
Habener, J.F.3
-
23
-
-
0028207389
-
Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of CDK5 in bovine brain
-
DOI 10.1016/0014-5793(94)80501-6
-
Ishiguro K., Kobayashi S., Omori A., Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of CDK5 in bovine brain FEBS Letters 1994 342 2 203 208 (Pubitemid 24115197)
-
(1994)
FEBS Letters
, vol.342
, Issue.2
, pp. 203-208
-
-
Ishiguro, K.1
-
24
-
-
0004291325
-
-
New York, NY, USA Wiley-Liss
-
Stein G. S., Baserga R., Giordano A., Denhardt D. T., The Molecular Basis of Cell Cycle and Growth Control 1999 28 New York, NY, USA Wiley-Liss
-
(1999)
The Molecular Basis of Cell Cycle and Growth Control
, vol.28
-
-
Stein, G.S.1
Baserga, R.2
Giordano, A.3
Denhardt, D.T.4
-
26
-
-
0035754080
-
To cycle or not to cycle: A critical decision in cancer
-
Malumbres M., Barbacid M., To cycle or not to cycle: a critical decision in cancer Nature Reviews Cancer 2001 1 3 222 231 (Pubitemid 33741897)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.3
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
27
-
-
74949134147
-
Cdk5, the multifunctional surveyor
-
Lalioti V., Pulido D., Sandoval I. V., Cdk5, the multifunctional surveyor Cell Cycle 2010 9 2 284 311
-
(2010)
Cell Cycle
, vol.9
, Issue.2
, pp. 284-311
-
-
Lalioti, V.1
Pulido, D.2
Sandoval, I.V.3
-
28
-
-
58149089468
-
CDK5-dependent phosphorylation of the Rho family GTPase TC10 regulates insulin-stimulated GLUT4 translocation
-
Okada S., Yamada E., Saito T., Ohshima K., Hashimoto K., Yamada M., Uehara Y., Tsuchiya T., Shimizu H., Tatei K., Izumi T., Yamauchi K., Hisanaga S. I., Pessin J. E., Mori M., CDK5-dependent phosphorylation of the Rho family GTPase TC10 regulates insulin-stimulated GLUT4 translocation Journal of Biological Chemistry 2008 283 51 35455 35463
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.51
, pp. 35455-35463
-
-
Okada, S.1
Yamada, E.2
Saito, T.3
Ohshima, K.4
Hashimoto, K.5
Yamada, M.6
Uehara, Y.7
Tsuchiya, T.8
Shimizu, H.9
Tatei, K.10
Izumi, T.11
Yamauchi, K.12
Hisanaga, S.I.13
Pessin, J.E.14
Mori, M.15
-
29
-
-
63149115282
-
The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes
-
Lalioti V., Muruais G., Dinarina A., van Damme J., Vandekerckhove J., Sandoval I. V., The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes Proceedings of the National Academy of Sciences of the United States of America 2009 106 11 4249 4253
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.11
, pp. 4249-4253
-
-
Lalioti, V.1
Muruais, G.2
Dinarina, A.3
Van Damme, J.4
Vandekerckhove, J.5
Sandoval, I.V.6
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