Nephroprotective effect of vanillic acid against cisplatin induced nephrotoxicity in wistar rats: A biochemical and molecular study

Environmental Toxicology and Pharmacology

Volumn 39, Issue 1, 2015, Pages 392-404

  Sindhu, Ganapathy ^a   Nishanthi, Emayavaramban ^a   Sharmila, Ramalingam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidants; Cisplatin; Nephroprotective; NF B; TNF ; Vanillic acid

Indexed keywords

BIOLOGICAL MARKER; CREATININE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 2; LIPID; MESSENGER RNA; NITROGEN; TUMOR NECROSIS FACTOR ALPHA; UREA; URIC ACID; VANILLIC ACID; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CISPLATIN; REACTIVE OXYGEN METABOLITE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; KIDNEY FUNCTION; LIPID PEROXIDATION; MALE; NEPHRITIS; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; KIDNEY; KIDNEY DISEASES; LIVER; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CISPLATIN; INTERLEUKIN-10; INTERLEUKIN-2; KIDNEY; KIDNEY DISEASES; LIVER; MALE; NF-KAPPA B; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VANILLIC ACID;

EID: 84920124218     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.12.008     Document Type: Article

References (62)

1. Arany I., Safirstein R.L. Cisplatin nephrotoxicity. Semin. Nephrol. 2003, 23:460-464.
2. Arjumand W., Seth A., Sultana S. Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NF-κB, TNF-α and caspase-3 expression in wistar rats. Food Chem. Toxicol. 2011, 49:2013-2021.
3. Ascon D.B., Lopez Briones S., Liu M., Ascon M., Savransky V., Colvin R.B., Soloski M.J., Rabb H. Phenotypic and functional characterization of kidney-infiltrating lymphocytes in renal ischemia reperfusion injury. J. Immunol. 2006, 177:3380-3387.
4. Bamboat Z.M., Ocuin L.M., Balachandran V.P., Obaid H., Plitas G., Dematteo R.P. Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. J. Clin. Invest. 2010, 120:559-569.
5. Bonsnes R.W., Taussky H.H. On the colorimetric determination of creatinine by the Jaffee reaction. J. Biol. Chem. 1945, 158:581-591.
6. Brown H. The determination of uric acid in human blood. J. Biol. Chem. 1945, 158:601-608.
7. Cichocki M., Blumczyńska J., Baer-Dubowska W. Naturally occurring phenolic acids inhibit 12-O-tetradecanoylphorbol-13-acetate induced NF-kappaB, iNOS and COX-2 activation in mouse epidermis. Toxicology 2010, 268:118-124.
8. Chou T.H., Ding H.Y., Hung W.J., Liang C.H. Antioxidative characteristics and inhibition of alpha-melanocyte-stimulating hormone-stimulated melanogenesis of vanillin and vanillic acid from Origanumvulgare. Exp. Dermatol. 2010, 19:742-750.
9. Collins T., Read M.A., Neish A.S., Whitley M.Z., Thanos D., Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappaB and cytokine-inducible enhancers. FASEB J. 1995, 9:899-909.
10. Deepa B., Anuradha C.V. Linalool, a plant derived monoterpene alcohol, rescues kidney from diabetes-induced nephropathic changes via blood glucose reduction. Diabetol. Croat. 2011, 40:121-137.
11. Deepa Mol S., Raja B. Therapeutic effects of vanillic acid on acetaminophen-induced hepatotoxicity in rats. Int. J. Pharm. Biol. Arch. 2010, 1:144-149.
12. Delaquis P., Stanich K., Toivonen P. Effect of pH on the inhibition of Listera spp. by vanillin and vanillic acid. J. Food Prot. 2005, 68:1472-1476.
13. Del Rio D., Rodriguez-Mateos A., Spencer J.P., Tognolini M., Borges G., Crozier A. Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid. Redox Signal. 2013, 18:1818-1892.
14. Durant S., Karran P. Vanillins - a novel family of DNA-PK inhibitors. Nucleic Acids Res. 2003, 31:5501-5512.
15. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 1959, 82:70-77.
16. Erdem M.G., Cinkilic N., Vatan O., Yilmaz D., Bagdas D., Bilaloglu R. Genotoxic and anti-genotoxic effects of vanillic acid against mitomycin C induced genomic damage in humanlymphocytes in vitro. Asian Pac. J. Cancer Prev. 2012, 13:4993-4998.
17. Faubel S., Lewis E.C., Reznikov L., Ljubanovic D., Hoke T.S., Somerset H., Oh D.J., Lu L., Klein C.L., Dinarello C.A., Edelstein C.L. Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. J. Pharmacol. Exp. Ther. 2007, 322:8-15.
18. Fraga C.G., Leibovitz B.E., Tappel A.L. Lipid peroxidation measured as TBARS in tissue slices: characterization and comparison with homogenates and microsomes. Free Radic. Biol. Med. 1988, 4:155-161.
19. Furuichi K., Wada T., Iwata Y., Kitagawa K., Kobayashi K., Hashimoto H., Ishiwata Y., Tomosugi N., Mukaida N., Matsushima K. Gene therapy expressing amino-terminal truncated monocyte chemoattractant protein-1 prevents renal ischemia-reperfusion injury. J. Am. Soc. Nephrol. 2003, 14:1066-1071.
20. Gitzinger M., Kemmer C., Fluri D.A., El-Baba M.D., Weber W., Fussenegger M. The food additive vanillic acid controls transgene expression in mammalian cells and mice. Nucleic Acids Res. 2012, 40:1-15.
21. Goodman A.I., Olszanecki R., Yang L.M., Quan S., Li M., Omura S., Stec D.E., Abraham N.G. Heme oxygenase-1 protects against radiocontrast-induced acute kidney injury by regulating anti-apoptotic proteins. Kidney Int. 2007, 72:945-953.
22. Hawkins C.L., Brown B.E., Davies M.J. Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis. Arch. Biochem. Biophys. 2001, 395:137-145.
23. Huang L., Sung S.S., Lobo P.I., Brown M.G., Gregg R.K., Engelhard V.H., Okusa M.D. NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury. J. Immunol. 2007, 178:5899-5911.
24. Huang S.M., Chuang H.C., Wu C.H., Yen G.C. Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells. Mol. Nutr. Food Res. 2008, 52:940-949.
25. Huang L., Vergis A.L., Ye H., Bajwa A., Narayan V., Strieter R.M., Rosin D.L., Okusa M.D. IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia reperfusion injury. J. Clin. Invest. 2010, 120:331-342.
26. Husain K., Morris C., Whitworth C., Trammell G.L., Rybak L.P., Somani S.M. Protection by ebselen against cisplatininduced nephrotoxicity: antioxidant system. Mol. Cell. Biochem. 1998, 178:127-133.
27. Ikezumi Y., Kawachi H., Toyabe S., Uchiyama M., Shimizu F. Anti- CD5 monoclonal antibody ameliorates proteinuria and glomerular lesions in rat mesangio proliferative glomerulon ephritis. Kidney int 2000, 58:100-114.
28. Jiangping D., Yukimasa K., Hsi C., Yuqin W., Xuxhen H., Stephen M., Hewitt T.M., et al. Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury. Kidney Int. 2001, 60:2118-2128.
29. Kakihara T.C., Imai H., Hotta Y., Ikarashi A., Tanaka, Uchiyama M. Impaired tubular excretory function as a late renal side effect of chemotherapy in children. J. Pediatr. Hematol. Oncol. 2003, 25:209-214.
30. Kakkar P., Das B., Viswanathan P.N. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biophys. 1984, 21:130-132.
31. Kawai Y., Nakao T., Kunimura N., Kohda Y., Gemba M. Relationship of intracellular calcium and oxygen radicals to cisplatin-related renal cell injury. J. Pharmacol. Sci. 2006, 100:65-72.
32. 3-induced cardiotoxicity by sonchusasper in rat. J. Med. Plants Res. 2011, 5:2514-2520.
33. Kim M.C., Kim S.J., Kim D.S., Jeon Y.D., Park S.J., Lee H.S., Um J.Y., Hong S.H. Vanillic acid inhibits inflammatory mediators by suppressing NF-κB in lipopolysaccharide-stimulated mouse peritoneal macrophages. Immunopharmacol. Immunotoxicol. 2011, 33:525-532.
34. Kitching A.R., Katerelos M., Mudge S.J., Tipping P.G., Power D.A., Holdsworth S.R. Interleukin-10 mesangial proliferative glomerulonephritis. Clin. Exp. Immunol. 2002, 128:36-43.
35. Kumar S., Prahalathan P., Raja B. Antihypertensive and antioxidant potential of vanillic acid, a phenolic compound in L-NAME-induced hypertensive rats: a dose-dependence study. Redox Rep. 2011, 16:208-215.
36. Mattila P., Kumpulainen J. Determination of free and total phenolic acids in plant-derived foods by high performance liquid chromatography with diode-array detection. J. Agric. Food Chem. 2002, 50:3660-3667.
37. McCord J.M. The evolution of free radicals and oxidative stress. Am. J. Med. 2000, 108:652-659.
38. Mohana Lakshmi S., Usha Kiran Reddy T., Sandhya Rani K.S. A review on medicinal plants for nephroprotective activity. Asian J. Pharm. Clin. Res. 2012, 5:8-14.
39. Natelson S. Microtechniques of Clinical Chemistry for the Routine Laboratory 1957, 381. CC Thomas Publisher, Springfield, IL.
40. Negishi K., Sekine D., Morimitsu T., Suzuki T., Okugawa Y., Kawakami A., Otsuka C., Oyama H., Loakes D. A role of liver fatty acid-binding protein in cisplatin-induced acute renal failure. Kidney Int. 2007, 72:348-358.
41. Ogawa T., Nussler A.K., Tuzuner E., Neuhaus P., Kaminishi M., Mimura Y., Beger H.G. Contribution of nitric oxide to the protective effects of ischemic preconditioning in ischemia-reperfused rat kidneys. J. Lab. Clin. Med. 2001, 138:50-58.
42. Rai R.P., Maurya M.S. Synthesis and evaluation of antibacterial activity of vanillin derivatives. J. Sci. Technol. India 1996, 4:275-276.
43. Ramesh G., Reeves W.B. TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity. J. Clin. Invest. 2002, 110:835-842.
44. Rodrigues A.J., Evora P.R., Bassetto S., Alves Júnior L., Scorzoni Filho A., Araújo W.F., Vicente W.V. Risk factors for acute renal failure after heart surgery. Rev. Bras. Cir. Cardiovasc. 2009, 24:441-446.
45. Ronald P., Miller Raghu K., Tadagavadi Ramesh G., Reeves W.B. Mechanism of cisplatin nephrotoxicity. Toxins 2010, 2:2490-2518.
46. Rotruck J.T., Pope A.L., Ganther H.T., Swanson A.B., Hafeman D.G., Hoekstra W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973, 179:588-590.
47. Sahreen S., Khan M.R., Khan R.A. Evaluation of antioxidant activities of various solvent extracts of Carissa opaca fruits. Food Chem. 2010, 122:1205-1211.
48. Sahu B.D., Kuncha M., Sindhura G.J., Sistla R. Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage. Phytomedicine 2013, 20:453-460.
49. Sultana S., Verma K., Khan R. Nephroprotective efficacy of chrysin againstcisplatin-induced toxicity via attenuation of oxidative stress. J. Pharm. Pharmacol. 2012, 64:872-881.
50. Shaughnessy D.T., Setzer R.W., Demarini D.H. The antimutagenic effect of vanillin and cinnamaldehyde on spontaneous mutation in Salmonella TA104 is due to a reduction in mutations at GC but not AT sites. Mutat. Res. 2001, 481:55-59.
51. Singh M., Tiwari V., Jain A., Ghoshal S. Protective activity of picroliv on hepatic amoebiasis associated with carbon tetrachloride toxicity. Indian J. Med. Res. 2005, 121:676-682.
52. Sinha K.A. Colorimetric assay of catalase. Anal. Biochem. 1972, 17:389-394.
53. Stanely Mainzen Prince P., Rajakumar S., Dhanasekar K. Protective effects of vanillic acid on electrocardiogram, lipid peroxidation, antioxidants, proinflammatory markers and histopathology in isoproterenol induced cardiotoxic rats. Eur. J. Pharmacol. 2011, 668:233-240.
54. Sung M.J., Kim D.H., Jung Y.J., Kang K.P., Lee A.S., Lee S., Kim W., Davaatseren M., Hwang J.T., Kim H.J., Kim M.S., Kwon D.Y., Park S.K. Genistein protects the kidney from cisplatin-induced injury. Kidney Int. 2008, 74:1538-1547.
55. Tsuda H., Veheara N., Iigo M., Nagao M., Ito M., Hirono I. Chemopreventive effects of β-carotene, α-tocopherol and five naturally occurring antioxidants on initiation of hepato carcinogenesis by 2-aminop-3-methylimidazo (4,5-f) quinoline in the rat. J. Cancer Res. 1994, 85:1214-1219.
56. Ueki M., Ueno M., Morishita J., Maekawa N. Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice. J. Biosci. Bioeng. 2013, 115:547-551.
57. Varma R.S., Shukla A., Chatterjee R.K. Evaluation of vanillic acid analogues as a new class of antifilarial agents. Indian J. Exp. Biol. 1993, 31:819-821.
58. Wang W., Reeves W.B., Ramesh G. Netrin-1 and kidney injury. I. Netrin-1 protects against ischemia-reperfusion injury of the kidney. Am. J. Physiol. Renal Physiol. 2008, 294:739-747.
59. Wu G., Fang Y.Z., Yang S., Lupton J.R., Turner N.D. Glutathione metabolism and its implications for health. J. Nutr. 2004, 134:489-492.
60. Yao X., Panichpisal K., Krtzman N., Nugent K. Cisplatin nephrotoxicity: a review. Am. J. Med. Sci. 2007, 334:115-124.
61. Yilmaz H.R., Iraz M., Sogut S., Ozyurt H., Yildirim Z., Akyol O., Gergerlioglu S. The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats. Pharmacol. Res 2004, 50:287-290.
62. Zhang B., Ramesh G., Uematsu S., Akira S., Reeves W.B. TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. J. Am. Soc. Nephrol. 2008, 19:923-932.