Gene therapy expressing amino-terminal truncated monocyte chemoattractant protein-1 prevents renal ischemia-reperfusion injury

Journal of the American Society of Nephrology

Volumn 14, Issue 4, 2003, Pages 1066-1071

  Furuichi, Kengo ^a   Wada, Takashi ^a,b   Iwata, Yasunori ^a   Kitagawa, Kiyoki ^a   Kobayashi, Ken Ichi ^a   Hashimoto, Hiroyuki ^c   Ishiwata, Yoshiro ^c   Tomosugi, Naohisa ^d   Mukaida, Naofumi ^b   Matsushima, Kouji ^e   Egashira, Kensuke ^f   Yokoyama, Hitoshi ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^d KANAZAWA MEDICAL UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; GENE PRODUCT; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN 7ND; UNCLASSIFIED DRUG;

7ND GENE; ACUTE KIDNEY TUBULE NECROSIS; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DELETION MUTANT; GENE; GENE THERAPY; GENETIC TRANSFECTION; IN VIVO STUDY; KIDNEY ARTERY STENOSIS; KIDNEY ISCHEMIA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VEIN OCCLUSION;

EID: 0037378038     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000059339.14780.E4     Document Type: Article

References (27)

1. Grace PA: Ischemia-reperfusion injury. Br J Surg 81: 637-647, 1994
2. Shiskes DA, Halloran PD: Delayed graft function in renal transplantation: etiology, management and long-term significance. J Urol 155: 1831-1840, 1996
3. Matsushima K, Larrsen CG, DuBois GC, Oppenheim JJ: Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. J Exp Med 169: 1485-1490, 1989
4. Yoshimura T, Robinson EA, Tanaka S, Appella E, Leonard EJ: Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglufinin-stimulated human blood mononuclear cell. J Immunol 142: 1956-1962, 1989
5. Segerer S, Nelson PJ, Schlondorff D: Chemokines, chemokine receptors, and renal disease: From basic science to pathophysiologic and therapeutic studies. J Am Soc Nephrol 11: 152-176, 2000
6. Vielhauer V, Anders HJ, Mack M, Cihak J, Strutz F, Stangassinger, M, Luckow B, Grone HJ, Schlondorff D: Obstructive nephropathy in the mouse: Progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation of CC chemokine receptor 2- and 5-positive leukocytes. J Am Soc Nephrol 12: 1173-1187, 2001
7. Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N: Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci USA 94: 12053-12058, 1997
8. Kurihara T, Warr G, Loy J, Bravo R: Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med 186: 1757-1762, 1997
9. Zhang Y, Rollins BJ: A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer. Mol Cell Biol 15: 4851-4855, 1995
10. Haq M, Norman J, Saba SR, Ramirez G, Rabb H: Role of IL-1 in renal ischemic reperfusion injury. J Am Soc Nephrol 9: 614-619, 1998
11. Ajuebor MN, Gibbs L, Flower RJ, Das AM, Perretti M: Investigation of the functional role played by the chemokine monocyte chemoattractant protein-1 in interleukin-1-induced murine perionitis. Br J Pharmacol 125: 319-326, 1998
12. Johnston B, Burns AR, Suematsu M, Issekutz TB, Woodman RC, Kubes P: Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1. J Clin Invest 103: 1269-1276, 1999
13. Tessier PA, Cattaruzzi P, McColl SR: Inhibition of lymphocyte adhesion to cytokine-activated synovial fibroblasts by glucocorticoids involves the attenuation of vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 gene expression. Arthritis Rheum 39: 226-234, 1996
14. Johnston B, Burns AR, Suematsu M, Issekutz TB, Woodman RC, Kubes P: Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1. J Clin Invest 103: 1269-1276, 1999
15. Blease K, Mehrad B, Standiford TJ, Lukacs NW, Gosling J, Boring L, Charo IF, Kunkel SL, Hogaboam CM: Enhanced pulmonary allergic responses to Aspergillus in CCR2-/- mice. J Immunol 165: 2603-2611, 2000
16. Zhang XW, Wang Y, Liu Q, Thorlacius H: Redundant function of macrophage inflammatory protein-2 and KC in tumor necrosis factor-alpha-induced extravasation of neutrophils in vivo. Eur J Pharmacol 427: 277-283, 2001
17. Witko-Sarsat V, Rieu P, Descamps-Latscha B, Lesavre P, Halbwachs-Mecarelli L: Neutrophils: Molecules, functions and pathophysiological aspects. Lab Invest 80: 617-653, 2000
18. Takada M, Nadeau KC, Shaw GD, Marquette KA, Tilney NL: The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. J Clin Invest 99: 2682-2690, 1997
19. Baggiolini M, Dewald B, Moser B: Interleukin-8 and related chemotactic cytokiens-CXC and CC chemokines. Adv Immunol 55: 97-179, 1994
20. Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ: Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 187: 601-608, 1998
21. Gong JH, Uguccioni M, Dewald B, Baggiolini M, Clark-Lewis I: RANTES and MCP-3 antagonists bind multiple chemokine receptors. J Biol Chem 271: 10521-10527, 1996
22. Gong JH, Clark-Lewis I: Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues. J Exp Med 181: 631-640, 1995
23. Ni W, Egashira K, Kitamoto S, Kataoka C, Koyanagi M, Inoue S, Imaizumi K, Akiyama C, Nishida, Ki K, Takeshita A: New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout mice. Circulation 103: 2096-2101, 2001
24. Egashira K, Koyanagi M, Kitamoto S, Ni W, Kataoka C, Morishita R, Kaneda Y, Akiyama C, Nishida KI, Sueishi K, Takeshita A: Anti-monocyte chemoattractant protein-1 gene therapy inhibits vascular remodeling in rats: Blockade of MCP-1 activity after intramuscular transfer of a mutant gene inhibits vascular remodeling induced by chronic blockade of NO synthesis. FASEB J 14: 1974-1978, 2000
25. Furuichi K, Wada T, Iwata Y, Sakai N, Yoshimoto K, Kobayashi K, Mukaida N, Matsushima K, Yokoyama H: Administration of FR167653, a new anti-inflammatory compound, prevents renal ischaemia/reperfusion injury in mice. Nephrol Dial Transplant 17: 399-407, 2002
26. De Greef KE, Ysebaert DK, Ghielli M, Vercauteren S, Nouwen EJ, Eyskens EJ, De Broe ME: Neutrophils and acute ischemia-reperfusion injury. J Nephrol 11: 110-122, 1998
27. Kim JS, Gautam SC, Chopp M, Zaloga C, Jones ML, Ward PA, Welch KM: Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat. J Neuroimmunol 56: 127-134, 1995