Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 3, 2015, Pages 473-481

  Komatsu, Michiharu ^a   Kimura, Takefumi ^a,b   Yazaki, Masahide ^a,c   Tanaka, Naoki ^a,b   Yang, Yang ^b   Nakajima, Takero ^b   Horiuchi, Akira ^d   Fang, Zhong Ze ^e   Joshita, Satoru ^a   Matsumoto, Akihiro ^a   Umemura, Takeji ^a   Tanaka, Eiji ^a   Gonzalez, Frank J ^f   Ikeda, Shu ichi ^a   Aoyama, Toshifumi ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c SHINSHU UNIVERSITY   (Japan)

^d Digestive Disease Center Showa Inan General Hospital   (Japan)

^e TIANJIN MEDICAL UNIVERSITY   (China)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

JNK; Mitochondrial oxidation; NAFLD; PPAR ; SLC25A13; Urea cycle disorder

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE I; CD36 ANTIGEN; FATTY ACID; FATTY ACID BINDING PROTEIN; KETONE BODY; LIPID TRANSFER PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN; CARRIER PROTEIN; SLC25A13 PROTEIN, HUMAN;

ADULT; AMMONIA BLOOD LEVEL; ARTICLE; BLOOD LEVEL; CITRULLINEMIA TYPE II; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; FATTY LIVER; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HYDROLYSIS; LIPID METABOLISM; LIPOGENESIS; LIVER LEVEL; MALE; MITOCHONDRIAL RESPIRATION; PHENOTYPE; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; STEATOSIS; UREA CYCLE DISORDER; BIOSYNTHESIS; CITRULLINEMIA; COMPLICATION; GENETICS; LIVER MITOCHONDRION; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; CITRULLINEMIA; DOWN-REGULATION; FATTY ACIDS; FATTY LIVER; FEMALE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KETONE BODIES; LIPID METABOLISM; MALE; MIDDLE AGED; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; PPAR ALPHA; RNA, MESSENGER; TRIGLYCERIDES;

EID: 84920094651     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.12.011     Document Type: Article

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