-
1
-
-
40849083460
-
Non-alcoholic fatty liver disease: The mist gradually clears
-
N.M. de Alwis, and C.P. Day Non-alcoholic fatty liver disease: the mist gradually clears J Hepatol 48 2008 S104 S112
-
(2008)
J Hepatol
, vol.48
-
-
De Alwis, N.M.1
Day, C.P.2
-
3
-
-
0033200054
-
Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
-
E.M. Brunt, C.G. Janney, A.M. Di Bisceglie, B.A. Neuschwander-Tetri, and B.R. Bacon Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions Am J Gastroenterol 94 1999 2467 2474
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 2467-2474
-
-
Brunt, E.M.1
Janney, C.G.2
Di Bisceglie, A.M.3
Neuschwander-Tetri, B.A.4
Bacon, B.R.5
-
4
-
-
0033038672
-
Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
-
C.A. Matteoni, Z.M. Younossi, T. Gramlich, N. Boparai, Y.C. Liu, and A.J. McCullough Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity Gastroenterology 116 1999 1413 1419
-
(1999)
Gastroenterology
, vol.116
, pp. 1413-1419
-
-
Matteoni, C.A.1
Younossi, Z.M.2
Gramlich, T.3
Boparai, N.4
Liu, Y.C.5
McCullough, A.J.6
-
5
-
-
77953739548
-
Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: A 27-year follow-up case
-
T. Nagaya, N. Tanaka, M. Komatsu, T. Ichijo, K. Sano, and A. Horiuchi Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case Clin J Gastroenterol 1 2008 116 121
-
(2008)
Clin J Gastroenterol
, vol.1
, pp. 116-121
-
-
Nagaya, T.1
Tanaka, N.2
Komatsu, M.3
Ichijo, T.4
Sano, K.5
Horiuchi, A.6
-
6
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
J.D. Browning, and J.D. Horton Molecular mediators of hepatic steatosis and liver injury J Clin Invest 114 2004 147 152
-
(2004)
J Clin Invest
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
7
-
-
0025178612
-
The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years
-
E.E. Powell, W.G. Cooksley, R. Hanson, J. Searle, J.W. Halliday, and L.W. Powell The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years Hepatology 11 1990 74 80
-
(1990)
Hepatology
, vol.11
, pp. 74-80
-
-
Powell, E.E.1
Cooksley, W.G.2
Hanson, R.3
Searle, J.4
Halliday, J.W.5
Powell, L.W.6
-
8
-
-
0033019013
-
Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease
-
S.H. Caldwell, D.H. Oelsner, J.C. Iezzoni, E.E. Hespenheide, E.H. Battle, and C.J. Driscoll Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease Hepatology 29 1999 664 669
-
(1999)
Hepatology
, vol.29
, pp. 664-669
-
-
Caldwell, S.H.1
Oelsner, D.H.2
Iezzoni, J.C.3
Hespenheide, E.E.4
Battle, E.H.5
Driscoll, C.J.6
-
9
-
-
33748304407
-
Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population
-
N. Tanaka, E. Tanaka, Y. Sheena, M. Komatsu, W. Okiyama, and N. Misawa Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population Liver Int 26 2006 956 963
-
(2006)
Liver Int
, vol.26
, pp. 956-963
-
-
Tanaka, N.1
Tanaka, E.2
Sheena, Y.3
Komatsu, M.4
Okiyama, W.5
Misawa, N.6
-
10
-
-
53249111691
-
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease
-
M. Komatsu, M. Yazaki, N. Tanaka, K. Sano, E. Hashimoto, and Y. Takei Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease J Hepatol 49 2008 810 820
-
(2008)
J Hepatol
, vol.49
, pp. 810-820
-
-
Komatsu, M.1
Yazaki, M.2
Tanaka, N.3
Sano, K.4
Hashimoto, E.5
Takei, Y.6
-
11
-
-
48949099031
-
Insulin resistance and hepatitis C virus: A case-control study of non-obese, non-alcoholic and non-steatotic hepatitis virus carriers with persistently normal serum aminotransferase
-
N. Tanaka, T. Nagaya, M. Komatsu, A. Horiuchi, G. Tsuruta, and H. Shirakawa Insulin resistance and hepatitis C virus: a case-control study of non-obese, non-alcoholic and non-steatotic hepatitis virus carriers with persistently normal serum aminotransferase Liver Int 28 2008 1104 1111
-
(2008)
Liver Int
, vol.28
, pp. 1104-1111
-
-
Tanaka, N.1
Nagaya, T.2
Komatsu, M.3
Horiuchi, A.4
Tsuruta, G.5
Shirakawa, H.6
-
12
-
-
33645970201
-
Laparoscopic findings in patients with nonalcoholic steatohepatitis
-
N. Tanaka, T. Ichijo, W. Okiyama, H. Mutou, N. Misawa, and A. Matsumoto Laparoscopic findings in patients with nonalcoholic steatohepatitis Liver Int 26 2006 32 38
-
(2006)
Liver Int
, vol.26
, pp. 32-38
-
-
Tanaka, N.1
Ichijo, T.2
Okiyama, W.3
Mutou, H.4
Misawa, N.5
Matsumoto, A.6
-
13
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, and O.W. Cummings Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 2005 1313 1321
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
-
14
-
-
55549107478
-
Investigation of the role of SREBP-1c in the pathogenesis of HCV-related steatosis
-
S. McPherson, J.R. Jonsson, H.D. Barrie, P. O'Rourke, A.D. Clouston, and E.E. Powell Investigation of the role of SREBP-1c in the pathogenesis of HCV-related steatosis J Hepatol 49 2008 1046 1054
-
(2008)
J Hepatol
, vol.49
, pp. 1046-1054
-
-
McPherson, S.1
Jonsson, J.R.2
Barrie, H.D.3
O'Rourke, P.4
Clouston, A.D.5
Powell, E.E.6
-
15
-
-
0028960739
-
Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
-
X. Hua, J. Wu, J.L. Goldstein, M.S. Brown, and H.H. Hobbs Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13 Genomics 25 1995 667 673
-
(1995)
Genomics
, vol.25
, pp. 667-673
-
-
Hua, X.1
Wu, J.2
Goldstein, J.L.3
Brown, M.S.4
Hobbs, H.H.5
-
16
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
I. Shimomura, H. Shimano, J.D. Horton, J.L. Goldstein, and M.S. Brown Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells J Clin Invest 99 1997 838 845
-
(1997)
J Clin Invest
, vol.99
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
18
-
-
0024412071
-
Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. CDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
-
T. Aoyama, S. Yamano, D.J. Waxman, D.P. Lapenson, U.A. Meyer, and V. Fischer Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. CDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine J Biol Chem 264 1989 10388 10395
-
(1989)
J Biol Chem
, vol.264
, pp. 10388-10395
-
-
Aoyama, T.1
Yamano, S.2
Waxman, D.J.3
Lapenson, D.P.4
Meyer, U.A.5
Fischer, V.6
-
19
-
-
0029078041
-
Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients
-
T. Aoyama, M. Souri, S. Ushikubo, T. Kamijo, S. Yamaguchi, and R.I. Kelley Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients J Clin Invest 95 1995 2465 2473
-
(1995)
J Clin Invest
, vol.95
, pp. 2465-2473
-
-
Aoyama, T.1
Souri, M.2
Ushikubo, S.3
Kamijo, T.4
Yamaguchi, S.5
Kelley, R.I.6
-
20
-
-
34347406521
-
SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
-
P. Ferré, and F. Foufelle SREBP-1c transcription factor and lipid homeostasis: clinical perspective Horm Res 68 2007 72 82
-
(2007)
Horm Res
, vol.68
, pp. 72-82
-
-
Ferré, P.1
Foufelle, F.2
-
21
-
-
0037716940
-
In vivo stabilization of nuclear retinoid X receptor α in the presence of peroxisome proliferator-activated receptor α
-
N. Tanaka, K. Hora, H. Makishima, Y. Kamijo, K. Kiyosawa, and F.J. Gonzalez In vivo stabilization of nuclear retinoid X receptor α in the presence of peroxisome proliferator-activated receptor α FEBS Lett 543 2003 120 124
-
(2003)
FEBS Lett
, vol.543
, pp. 120-124
-
-
Tanaka, N.1
Hora, K.2
Makishima, H.3
Kamijo, Y.4
Kiyosawa, K.5
Gonzalez, F.J.6
-
22
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα)
-
T. Aoyama, J.M. Peters, N. Iritani, T. Nakajima, K. Furihata, and T. Hashimoto Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα) J Biol Chem 273 1998 5678 5684
-
(1998)
J Biol Chem
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
Nakajima, T.4
Furihata, K.5
Hashimoto, T.6
-
23
-
-
1542283630
-
Peroxisome proliferator-activated receptor α target genes
-
S. Mandard, M. Müller, and S. Kersten Peroxisome proliferator-activated receptor α target genes Cell Mol Life Sci 61 2004 393 416
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 393-416
-
-
Mandard, S.1
Müller, M.2
Kersten, S.3
-
24
-
-
69449086702
-
Comparative analysis of gene regulation by the transcription factor PPARα between mouse and human
-
M. Rakhshandehroo, G. Hooiveld, M. Müller, and S. Kersten Comparative analysis of gene regulation by the transcription factor PPARα between mouse and human PLoS One 4 2009 e6796
-
(2009)
PLoS One
, vol.4
, pp. 6796
-
-
Rakhshandehroo, M.1
Hooiveld, G.2
Müller, M.3
Kersten, S.4
-
25
-
-
63849335660
-
Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: A novel peroxisome proliferator-activated receptor α-independent mechanism
-
T. Nakajima, N. Tanaka, H. Kanbe, A. Hara, Y. Kamijo, and X. Zhang Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor α-independent mechanism Mol Pharmacol 75 2009 782 792
-
(2009)
Mol Pharmacol
, vol.75
, pp. 782-792
-
-
Nakajima, T.1
Tanaka, N.2
Kanbe, H.3
Hara, A.4
Kamijo, Y.5
Zhang, X.6
-
26
-
-
21344434775
-
Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells
-
E.L. Abbot, J.G. McCornack, C. Reynet, D.G. Hassall, K.W. Buchan, and S.J. Yeaman Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells FEBS J 272 2005 3004 3014
-
(2005)
FEBS J
, vol.272
, pp. 3004-3014
-
-
Abbot, E.L.1
McCornack, J.G.2
Reynet, C.3
Hassall, D.G.4
Buchan, K.W.5
Yeaman, S.J.6
-
27
-
-
62749136195
-
Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-δ and is of metabolic relevance in humans
-
H. Staiger, C. Haas, J. Machann, R. Werner, M. Weisser, and F. Schick Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-δ and is of metabolic relevance in humans Diabetes 58 2009 579 589
-
(2009)
Diabetes
, vol.58
, pp. 579-589
-
-
Staiger, H.1
Haas, C.2
MacHann, J.3
Werner, R.4
Weisser, M.5
Schick, F.6
-
28
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression
-
S. Yu, K. Matsusue, P. Kashireddy, W.Q. Cao, V. Yeldandi, and A.V. Yeldandi Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression J Biol Chem 278 2003 498 505
-
(2003)
J Biol Chem
, vol.278
, pp. 498-505
-
-
Yu, S.1
Matsusue, K.2
Kashireddy, P.3
Cao, W.Q.4
Yeldandi, V.5
Yeldandi, A.V.6
-
29
-
-
41449098953
-
Hepatic steatosis in leptin-deficient mice is promoted by the PPARγ target gene Fsp27
-
K. Matsusue, T. Kusakabe, T. Noguchi, S. Takiguchi, T. Suzuki, and S. Yamano Hepatic steatosis in leptin-deficient mice is promoted by the PPARγ target gene Fsp27 Cell Metab 7 2008 302 311
-
(2008)
Cell Metab
, vol.7
, pp. 302-311
-
-
Matsusue, K.1
Kusakabe, T.2
Noguchi, T.3
Takiguchi, S.4
Suzuki, T.5
Yamano, S.6
-
30
-
-
33846174641
-
Tumor necrosis factor and interleukin 1 decrease RXRα, PPARα, PPARγ, LXRα, and the coactivators SRC-1, PGC-1α, and PGC-1β in liver cells
-
M.S. Kim, T.R. Sweeney, J.K. Shigenaga, L.G. Chui, A. Moser, and C. Grunfeld Tumor necrosis factor and interleukin 1 decrease RXRα, PPARα, PPARγ, LXRα, and the coactivators SRC-1, PGC-1α, and PGC-1β in liver cells Metabolism 56 2007 267 279
-
(2007)
Metabolism
, vol.56
, pp. 267-279
-
-
Kim, M.S.1
Sweeney, T.R.2
Shigenaga, J.K.3
Chui, L.G.4
Moser, A.5
Grunfeld, C.6
-
31
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
I. Shimomura, Y. Bashmakov, and J.D. Horton Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus J Biol Chem 274 1999 30028 30032
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
33
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
N. Higuchi, M. Kato, Y. Shundo, H. Tajiri, M. Tanaka, and N. Yamashita Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease Hepatol Res 38 2008 1122 1129
-
(2008)
Hepatol Res
, vol.38
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
Tanaka, M.5
Yamashita, N.6
-
34
-
-
0032502704
-
Control of human muscle-type carnitine palmitoyltransferase i gene transcription by peroxisome proliferator-activated receptor
-
C. Mascaró, E. Acosta, J.A. Ortiz, P.F. Marrero, F.G. Hegardt, and D. Haro Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor J Biol Chem 273 1998 8560 8563
-
(1998)
J Biol Chem
, vol.273
, pp. 8560-8563
-
-
Mascaró, C.1
Acosta, E.2
Ortiz, J.A.3
Marrero, P.F.4
Hegardt, F.G.5
Haro, D.6
-
35
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
K.A. Burns, and J.P. Vanden Heuvel Modulation of PPAR activity via phosphorylation Biochim Biophys Acta 1771 2007 952 960
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
36
-
-
36749083957
-
Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor α in transgenic mice: Implications for HCV-associated hepatocarcinogenesis
-
N. Tanaka, K. Moriya, K. Kiyosawa, K. Koike, and T. Aoyama Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor α in transgenic mice: implications for HCV-associated hepatocarcinogenesis Int J Cancer 122 2008 124 131
-
(2008)
Int J Cancer
, vol.122
, pp. 124-131
-
-
Tanaka, N.1
Moriya, K.2
Kiyosawa, K.3
Koike, K.4
Aoyama, T.5
-
37
-
-
38849184816
-
PPARα activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice
-
N. Tanaka, K. Moriya, K. Kiyosawa, K. Koike, F.J. Gonzalez, and T. Aoyama PPARα activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice J Clin Invest 118 2008 683 694
-
(2008)
J Clin Invest
, vol.118
, pp. 683-694
-
-
Tanaka, N.1
Moriya, K.2
Kiyosawa, K.3
Koike, K.4
Gonzalez, F.J.5
Aoyama, T.6
-
38
-
-
67349132443
-
Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress
-
W. Okiyama, N. Tanaka, T. Nakajima, E. Tanaka, K. Kiyosawa, and F.J. Gonzalez Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress J Hepatol 50 2009 1236 1246
-
(2009)
J Hepatol
, vol.50
, pp. 1236-1246
-
-
Okiyama, W.1
Tanaka, N.2
Nakajima, T.3
Tanaka, E.4
Kiyosawa, K.5
Gonzalez, F.J.6
|