Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 51, 2014, Pages 18363-18368

  Ferrari, Luiz Fernando ^a   Lotufo, Celina Monteiro ^a,b   Araldi, Dionéia ^c   Rodrigues, Marcos A ^a   Macedo, Larissa P ^b   Ferreira, Sérgio H ^a   Parada, Carlos Amilcar ^c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Dorsal root ganglion; Hyperalgesia; Inflammatory pain; NMDA receptor; Satellite cells

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6,7 DINITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; CALCIUM; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2D; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 3A; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; 6,7-DINITRODIHYDROQUINOXALINE-2,3-DIONE; QUINOXALINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTISENSE THERAPY; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM SENSITIZATION; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; FLUORESCENCE IMAGING; FOREFOOT; GENE SILENCING; HYPERALGESIA; IN VITRO STUDY; LUMBAR SPINE; MALE; MECHANICAL STIMULATION; NERVE CELL CULTURE; NEUROTRANSMITTER RELEASE; NONHUMAN; PAIN RECEPTOR; RAT; SATELLITE CELL; SPINAL GANGLION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; METABOLISM;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; DINOPROSTONE; GANGLIA, SPINAL; HYPERALGESIA; NOCICEPTORS; QUINOXALINES; RATS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SATELLITE CELLS, PERINEURONAL;

EID: 84919941462     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420601111     Document Type: Article

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