Distribution of the glutamate transporters GLAST and GLT-1 in rat circumventricular organs, meninges, and dorsal root ganglia

Journal of Comparative Neurology

Volumn 421, Issue 3, 2000, Pages 385-399

  Berger, Urs V ^a   Hediger, Matthias A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

EAAT1; EAAT2; In situ hybridization

Indexed keywords

GLUTAMATE TRANSPORTER;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MENINX; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL GANGLION;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; GANGLIA, SPINAL; MALE; MENINGES; NEURONS; NEUROSECRETORY SYSTEMS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUBFORNICAL ORGAN;

EID: 0034608271     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(20000605)421:3<385::AID-CNE7>3.0.CO;2-S     Document Type: Article

References (57)

1. Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG. 1994. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-5569.
2. Arriza JL, Eliasof S, Kavanaugh MP, Amara SG. 1997. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 94:4155-4160.
3. Berger UV, Hediger MA. 1998. Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization. Anat Embryol (Berl) 198:13-30.
4. Berger UV, Hediger MA. 1999. Distribution of peptide transporter PEPT2 mRNA in the rat nervous system. Anat Embryol (Berl) 199:439-449.
5. Bongianni F, Mutolo D, Carfi M, Pantaleo T. 1998. Area postrema glutamate receptors mediate respiratory and gastric responses in the rabbit. Neuroreport 9:2057-2062.
6. Boya J, Calvo JL. 1993. Immunohistochemical study of the pineal astrocytes in the postnatal development of the cat and dog pineal gland. J Pineal Res 15:13-20.
7. Bridges RJ, Lovering FE, Koch H, Cotman CW, Chamberlin AR.1994. A conformationally constrained competitive inhibitor of the sodium- dependent glutamate transporter in forebrain synaptosomes: L-anti-endo- 3,4-methanopyrrolidine dicarboxylate. Neurosci Lett 174:193-197.
8. Brooks-Kayal AR, Munir M, Jin H, Robinson MB. 1998. The glutamate transporter, GLT-1, is expressed in cultured hippocampal neurons. Neurochem Int 33:95-100.
9. Bunn SJ, Hanley MR, Wilkin GP. 1990. Pituitary astrocytes from the neural lobe of rats. A tissue culture and immunohistochemical study. Cell Tissue Res 260:589-594.
10. Calvo J, Boya J, Borregon A, Garcia-Maurino JE.1988. Presence of glial cells in the rat pineal gland: a light and electron microscopic immunohistochemical study. Anat Rec 220:424-428.
11. Carpenter DO, Briggs DB, Knox AP, Strominger N. 1988. Excitation of area postrema neurons by transmitters, peptides, and cyclic nucleotides. J Neurophysiol 59:358-369.
12. Chaudhry FA, Lehre KP, van Lookeren Campagne M, Ottersen OP, Danbolt NC, Storm-Mathisen J. 1995. Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15:711-720.
13. Chouaf L, Didier-Bazes M, Aguera M, Tardy M, Sallanon M, Kitahama K, Belin MF. 1989. Comparative marker analysis of the ependymocytes of the subcommissural organ in four different mammalian species. Cell Tissue Res 257:255-262.
14. Cocchia D, Miani N. 1980. Immunocytochemical localization of the brain-specific S-100 protein in the pituitary gland of adult rat. J Neurocytol 9:771-782.
15. Danbolt NC, Storm-Mathisen J, Kanner BI. 1992. An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes. Neuroscience 51:295-310.
16. Ebling FJ, Alexander IH, Urbanski HF, Hastings MH. 1995. Effects of N-methyl-D-aspartate (NMDA) on seasonal cycles of reproduction, body weight and pelage colour in the male Siberian hamster. J Neuroendocrinol 7:555-566.
17. Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG. 1995. An excitatory amino-acid transporter with properties of a ligandgated chloride channel. Nature 375:599-603.
18. Gary KA, Chronwall BM. 1995. Regulation of GFAP expression in glial-like cells of the rat pituitary intermediate lobe by lactation, salt-loading, and adrenalectomy. Glia 13:272-282.
19. Gary KA, Sands SA, Chronwall BM. 1995. Glial-like cells of the rat pituitary intermediate lobe change morphology and shift from vimentin to GFAP expression during development. Int J Dev Neurosci 13:555-565.
20. Gegelashvili G, Schousboe A. 1998. Cellular distribution and kinetic properties of high-affinity glutamate transporters. Brain Res Bull 45:233-238.
21. Gegelashvili G, Danbolt NC, Schousboe A. 1997. Neuronal soluble factors differentially regulate the expression of the GLT-1 and GLAST glutamate transporters in cultured astroglia. J Neurochem 69:2612-2615.
22. Haugeto O, Ullensvang K, Levy LM, Chaudhry FA, Honore T, Nielsen M, Lehre KP, Danbolt NC. 1996. Brain glutamate transporter proteins form homomultimers. J Biol Chem 271:27715-27722.
23. Johnson AK, Gross PM. 1993. Sensory circumventricular organs and brain homeostatic pathways. FASEB J 7:678-686.
24. Kanai Y, Hediger MA. 1992. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360:467-471.
25. Kiyama H, Sato K, Tohyama M. 1993. Characteristic localization of non-NMDA type glutamate receptor subunits in the rat pituitary gland. Brain Res Mol Brain Res 19:262-268.
26. Kugler P, Schmitt A. 1999. Glutamate transporter EAAC1 is expressed in neurons and glial cells in the rat nervous system. Glia 27:129-142.
27. Lehre KP, Danbolt NC. 1998. The number of glutamate transporter sub-type molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain. J Neurosci 18:8751-8757.
28. Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC. 1995. Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 15:1835-1853.
29. Levy LM, Lehre KP, Rolstad B, Danbolt NC. 1993. A monoclonal antibody raised against an [Na(+)+HK+]coupled L-glutamate transporter purified from rat brain confirms glial cell localization. FEBS Lett 317:79-84.
30. Lopez-Munoz F, Calvo JL, Boya J, Carbonell AL. 1992. Coexpression of vimentin and glial fibrillary acidic protein in glial cells of the adult rat pineal gland. J Pineal Res 12:145-148.
31. Martin LJ, Brambrink AM, Lehmann C, Portera-Cailliau C, Koebler R, Rothstein J, Traystman R J. 1997. Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum. Ann Neurol 42:335-348.
32. Mennerick S, Dhond HP, Benz A, Xu W, Rothstein JD, Danbolt NC, Isenberg KE, Zorumski CF. 1998. Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures. J Neurosci 18:4490-4499.
33. Meyer T, Munch C, Knappenberger B, Liebau S, Volkel H, Ludolph AC. 1998. Alternative splicing of the glutamate transporter EAAT2 (GLT-1). Neurosci Lett 241:68-70.
34. Munch C, Schwalenstocker B, Knappenberger B, Liebau S, Volkel H, Ludolph AC, Meyer T. 1998. 5′-heterogeneity of the human excitatory amino acid transporter cDNA EAAT2 (GLT-1). Neuroreport 9:1295-1297.
35. Nagai M, Abe K, Okamoto K, Itoyama Y. 1998. Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients. Neurosci Lett 244:165-168.
36. Northington FJ, Traystman RJ, Koehler RC, Martin LJ. 1999. GLT-1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain. J Neurobiol 39:515-526.
37. Pines G, Danbolt NC, Bjoras M, Zhang Y, Bendahan A, Eide L, Koepsell H, Storm-Mathisen J, Seeberg E, Kanner BI. 1992. Cloning and expression of a rat brain L-glutamate transporter [published erratum appears in Nature 1992 Dec 24-31;360(6406):768] [see comments]. Nature 360: 464-467.
38. Price MT, Olney JW, Lowry OH, Buchsbaum S. 1981. Uptake of exogenous glutamate and aspartate by circumventricular organs but not other regions of brain. J Neurochem 36:1774-1780.
39. Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW. 1994. Localization of neuronal and glial glutamate transporters. Neuron 13:713-725.
40. Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW. 1995. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84.
41. Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, Kanai Y, Hediger MA, Wang Y, Schielke JP, Welty DF. 1996. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16:675-686.
42. Schaeren-Wiemers N, Gerfin-Moser A. 1993. A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100:431-440.
43. Schmid HA. 1998. Effect of glutamate and angiotensin II on whole cell currents and release of nitric oxide in the rat subfornical organ. Amino Acids 14:113-119.
44. Schmitt A, Asan E, Puschel B, Jons T, Kugler P. 1996. Expression of the glutamate transporter GLT-1 in neural cells of the rat central nervous system: non-radioactive in situ hybridization and comparative immunocytochemistry. Neuroscience 71:989-1004.
45. Schmitt A, Asan E, Puschel B, Kugler P. 1997. Cellular and regional distribution of the glutamate transporter GLAST in the CNS of rats: nonradioactive in situ hybridization and comparative immunocytochemistry. J Neurosci 17:1-10.
46. Storck T, Schulte S, Hofmann K, Stoffel W. 1992. Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 89:10955-10959.
47. Sutherland ML, Delaney TA, Noebels JL. 1996. Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. J Neurosci 16:2191-2207.
48. Swanson RA, Liu J, Miller JW, Rothstein JD, Farrell K, Stein BA, Longuemare MC. 1997. Neuronal regulation of glutamate transporter subtype expression in astrocytes. J Neurosci 17:932-940.
49. Torp R, Danbolt NC, Babaie E, Bjoras M, Seeberg E, Storm-Mathisen J, Ottersen OP. 1994. Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study. Eur J Neurosci 6:936-942.
50. Torp R, Hoover F, Danbolt NC, Storm-Mathisen J, Ottersen OP. 1997. Differential distribution of the glutamate transporters GLT-1 and rEAAC1 in rat cerebral cortex and thalamus: an in situ hybridization analysis. Anat Embryol (Berl) 195:317-326.
51. Trotti D, Rolfs A, Danbolt NC, Brown RH, Jr, Hediger MA. 1999. SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter. Nat Neurosci 2:427-433.
52. Utsunomiya-Tate N, Endou H, Kanai Y. 1997. Tissue specific variants of glutamate transporter GLT-1. FEBS Lett 416:312-316.
53. Villalobos C, Nunez L, Garcia-Sancho J. 1996. Functional glutamate receptors in a subpopulation of anterior pituitary cells. FASEB J 10:654-660.
54. Wang GJ, Chung HJ, Schnuer J, Pratt K, Zable AC. Kavanaugh MP, Rosenberg PA. 1998. High affinity glutamate transport in rat cortical neurons in culture. Mol Pharmacol 53:88-96.
55. Yamada H, Yatsushiro S, Yamamoto A, Hayashi M, Nishi T, Futai M, Yamaguchi A, Moriyama Y. 1997. Functional expression of a GLT-1 type Na + -dependent glutamate transporter in rat pinealocytes. J Neurochem 69:1491-1498.
56. Yamada H, Yatsushiro S, Ishio S, Hayashi M, Nishi T, Yamamoto A, Futai M, Yamaguchi A, Moriyama Y. 1998a. Metabotropic glutamate receptors negatively regulate melatonin synthesis in rat pinealocytes. J Neurosci 18:2056-2062.
57. Yamada K, Watanabe M, Shibata T, Nagashima M, Tanaka K, Inoue Y. 1998b. Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression. J Neurosci 18:5706-5713.