Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: Implications for uncoupling endothelial nitric oxide synthase

Biochemical Pharmacology

Volumn 70, Issue 3, 2005, Pages 343-354

  Kuzkaya, Nermin ^b   Weissmann, Norbert ^b   Harrison, David G ^a   Dikalov, Sergey ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Ascorbate; eNOS; ESR; Nitric oxide; Peroxynitrite; Superoxide; Thiols; Urate

Indexed keywords

1 HYDROXY 3 METHOXYCARBONYL 2,2,5,5 TETRAMETHYLPYRROLIDINE; ANTIOXIDANT; ASCORBIC ACID; CYSTEINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PEROXYNITRITE; PYRROLIDINE DERIVATIVE; SUPEROXIDE; TETRAHYDROBIOPTERIN; THIOL DERIVATIVE; UNCLASSIFIED DRUG; URIC ACID; XANTHINE;

ACIDITY; ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON SPIN RESONANCE; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REDUCTION; STATISTICAL SIGNIFICANCE;

ANIMALS; ASCORBIC ACID; CATTLE; CELLS, CULTURED; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PEROXYNITROUS ACID; SULFHYDRYL COMPOUNDS; UNCOUPLING AGENTS; URIC ACID;

EID: 21344461736     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.05.009     Document Type: Article

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