Plasma metabolic profiling of dairy cows affected with clinical ketosis using LC/MS technology

Veterinary Quarterly

Volumn 34, Issue 3, 2014, Pages 152-158

  Li, Y ^a   Xu, C ^a   Xia, C ^a,b   Zhang, Hy ^a   Sun, Lw ^a   Gao, Y ^a  

^a HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

cattle; cow; ketosis; liquid chromatography mass spectrometry; metabolomics

Indexed keywords

ADULT; ARTICLE; CASE REPORT; FIBROMA; HUMAN; MALE; MOUTH TUMOR; PAPILLOMA; ANIMAL; BLOOD; BOVINE; CATTLE DISEASE; COMPARATIVE STUDY; DAIRYING; FEMALE; KETOACIDOSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; MULTIVARIATE ANALYSIS; PROCEDURES; SENSITIVITY AND SPECIFICITY; STANDARDS; VETERINARY;

ANIMALIA; BOS;

AMINO ACID; BIOLOGICAL MARKER; HYDROXYBUTYRIC ACID; LIPID;

AMINO ACIDS; ANIMALS; BIOLOGICAL MARKERS; CATTLE; CATTLE DISEASES; CHROMATOGRAPHY, LIQUID; DAIRYING; FEMALE; HYDROXYBUTYRATES; KETOSIS; LIPIDS; MASS SPECTROMETRY; MULTIVARIATE ANALYSIS; SENSITIVITY AND SPECIFICITY;

EID: 84919837993     PISSN: 01652176     EISSN: 18755941     Source Type: Journal    
DOI: 10.1080/01652176.2014.962116     Document Type: Article

References (32)

1. Al-Rawashdeh OF. 1999. Prevalence of ketonemia and associations with herd size, lactation stage, parity and postparturient diseases in Jordanian dairy cattle. Prev Vet Med. 40:117–125.
2. Chacher B, Liu H, Wang D, Liu J. 2013. Potential role of N-carbamoyl glutamate in biosynthesis of arginine and its significance in production of ruminant animals. J Anim Sci Biotechnol. 4:16.
3. Chen F, Xue J, Zhou L, Wu S, Chen Z. 2011. Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method. Anal Bioanal Chem. 401:1899–1904.
4. Chen GL, Miller GM. 2012. Advances in tryptophan hydroxylase-2 gene expression regulation: new insights into serotonin-stress interaction and clinical implications. Am J Med Genet B Neuropsychiatr Genet. 159B:152–171.
5. Cote JF, Curtis RA, McSherry BJ, Robertson JM, Kronfeld DS. 1969. Bovine ketosis: frequency of clinical signs, complications and alterations in blood ketones, glucose and free fatty acids. Can Vet J. 10:179–187.
6. Farid AS, Honkawa K, Fath EM, Nonaka N, Horii Y. 2013. Serum paraoxonase-1 as biomarker for improved diagnosis of fatty liver in dairy cows. BMC Vet Res. 9:73.
7. Forslund KB, Ljungvall OA, Jones BV. 2010. Low cortisol levels in blood from dairy cows with ketosis: a field study. Acta Vet Scand. 52:31.
8. Gaster M. 2012. A primary reduced TCA flux governs substrate oxidation in T2D skeletal muscle. Curr Diabetes Rev. 8:458–479.
9. Gerich JE, Meyer C, Woerle HJ, Stumvoll M. 2001. Renal gluconeogenesis: its importance in human glucose homeostasis. Diabetes Care. 24:382–391.
10. Gonzalez CI, Rosendo O. 2013. Assessment of fatty liver syndrome and its predisposing factors in a dairy herd from Venezuela. ISRN Vet Sci. 2013:191708.
11. Grummer RR, Carroll DJ. 1991. Effects of dietary fat on metabolic disorders and reproductive performance of dairy. J Anim Sci. 69:3838–3852.
12. Hale MW, Shekhar A, Lowry CA. 2011. Development by environment interactions controlling tryptophan hydroxylase expression. J Chem Neuroanat. 41:219–226.
13. Kuhla B, Albrecht D, Kuhla S, Metges CC. 2009. Proteome analysis of fatty liver in feed-deprived dairy cows reveals interaction of fuel sensing, calcium, fatty acid, and glycogen metabolism. Physiol Genomics. 37:88–98.
14. Lapierre H, Lobley GE, Doepel L, Raggio G, Rulquin H, Lemosquet S. 2012. Triennial lactation symposium: mammary metabolism of amino acids in dairy cows. J Anim Sci. 90:1708–2171.
15. Li Y, Su Z, Lin S, Li C, Ya Zhao, Gao X, Lai Y, Wu X, Wu H, Cai Z. 2014. Characterisation of the metabolism of pogostone in vitro and in vivo using liquid chromatography with mass spectrometry. Phytochem Anal. 25:97–105.
16. Miettinen PV. 1995. Prevention of bovine ketosis with glucogenic substance and its effect on fertility in Finnish dairy cows. Berl Munch Tierarztl Wochenschr. 108:14–19.
17. Nicholson JK, Lindon JC, Holmes E. 1999. Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic date. Xenobiotica. 29:1181–1189.
18. Oetzel GR. 2004. Monitoring and testing dairy herds for metabolic disease. Vet Clin North Am Food Anim Pract. 20:651–674.
19. Oresic M, Vidal-Puig A, Hänninen V. 2006. Metabolomic approaches to phenotype characterization and applications to complex diseases. Expert Rev Mol Diagn. 6:575–585.
20. Padilla L, Shibano K, Inoue J, Matsui T, Yano H. 2005. Plasma vitamin C concentration is not related to the incidence of ketosis in dairy cows during the early lactation period. J Vet Med Sci. 67:883–886.
21. Pan YH, Zhang Y, Cui J, Liu Y, McAllan BM, Liao CC, Zhang S. 2013. Adaptation of phenylalanine and tyrosine catabolic pathway to hibernation in bats. PLoS One. 8:e62039.
22. Schneider H, Ma L, Glatt H. 2003. Extractionless method for the determination of urinary caffeine metabolites using high-performance liquid chromatography coupled with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 789:227–237.
23. Steen A. 2001. Field study of dairy cows with reduced appetite in early lactation: clinical examinations, blood and rumen fluid analyses. Acta Vet Scand. 42:219–228.
24. Trygg J, Holmes E, Lundstedt T. 2007. Chemometrics in metabolomics. J Proteome Res. 6:469–479.
25. Van Knegsel AT, van den Brand H, Dijkstra J, Kemp B. 2007. Effects of dietary energy source on energy balance, metabolites and reproduction variables in dairy cows in early lactation. Theriogenology. 68:S274–S280.
26. Wagner S, Scholz K, Sieber M, Kellert M, Voelkel W. 2007. Tool in metabonomics: an integrated validation approach for LC-MS metabolic profiling of mercapturic acids in human urine. Anal Chem. 79:2918–2926.
27. Wang X, Li X, Zhao C, Hu P, Chen H, Liu Z, Liu G, Wang Z. 2012. Correlation between composition of the bacterial community and concentration of volatile fatty acids in the rumen during the transition period and ketosis in dairy cows. Appl Environ Microbiol. 78:2386–2392.
28. Wilson ID, Plumb R, Granger J, Major H, Williams R, Lenz EM. 2005. HPLC-MS-based methods for the study of metabonomics. J Chromatogr B Analyt Technol Biomed Life Sci. 817:67–76.
29. Woolbright BL, Jaeschke H. 2012. Novel insight into mechanisms of cholestatic liver injury. World J Gastroenterol. 18:4985–4993.
30. Yang J, Zhao X, Liu X, Wang C, Gao P, Wang J, Li L, Gu J, Yang S, Xu G. 2006. High performance liquid chromatography-mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B. J Proteome Res. 5:554–561.
31. Yang N, Feng S, Shedden K, Xie X, Liu Y, Rosser CJ, Lubman DM, Goodison S. 2011. Urinary glycoprotein biomarker discovery for bladder cancer detection using LC-MS/MS and label-free quantification. Clin Cancer Res. 17:3349–3359.
32. Zhang A, Sun H, Han Y, Yan G, Wang X. 2013. Urinary metabolic biomarker and pathway study of hepatitis B virus infected patients based on UPLC-MS system. PLOS One. 8:e64381.