Structural basis for the De-N-acetylation of poly-β-1,6-N-acetyl-D-glucosamine in gram-positive bacteria

Journal of Biological Chemistry

Volumn 289, Issue 52, 2014, Pages 35907-35917

  Little, Dustin J ^a,b   Bamford, Natalie C ^a,b   Pokrovskaya, Varvara ^c   Robinson, Howard ^d   Nitz, Mark ^c   Howell, P Lynne ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; BIOFILMS; CATALYSIS; ESCHERICHIA COLI; METABOLITES; PLANTS (BOTANY); QUANTUM CHEMISTRY;

ACTIVE SITE RESIDUES; CARBOHYDRATE ESTERASE; CATALYTIC MECHANISMS; EXTRACELLULAR PROTEINS; GRAM-NEGATIVE SPECIES; GRAM-POSITIVE BACTERIUM; MEMBRANE ASSOCIATION; STRUCTURAL COMPARISON;

ACETYLATION;

ARGININE; COBALT; EXTRACELLULAR PROTEIN ICAB; N ACETYLGLUCOSAMINE; NICKEL; OLIGOMER; PEPTIDES AND PROTEINS; POLY BETA 1,6 N ACETYL DEXTRO GLUCOSAMINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; ZINC ION; AMIDASE; BACTERIAL PROTEIN; BETA GLUCAN; POLY-N-ACETYL-1-6-GLUCOSAMINE; POLYSACCHARIDE DEACETYLASE; PROTEIN BINDING; ZINC;

AMMONIFEX DEGENSII; ARTICLE; BINDING SITE; BIOFILM; CARBOHYDRATE SYNTHESIS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DEACETYLATION; ENZYME ACTIVITY; ENZYME MECHANISM; ESCHERICHIA COLI; GRAM POSITIVE BACTERIUM; HYDROPHOBICITY; MEMBRANE BIOLOGY; MOLECULAR DOCKING; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STABILITY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ACETYLATION; AMINO ACID SEQUENCE; CHEMICAL PHENOMENA; CHEMISTRY; CONSERVED SEQUENCE; ENDOSPORE-FORMING RODS AND COCCI; ENZYME ACTIVE SITE; ENZYMOLOGY; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ACETYLATION; AMIDOHYDROLASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BETA-GLUCANS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GRAM-POSITIVE ENDOSPORE-FORMING RODS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; ZINC;

EID: 84919799322     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.611400     Document Type: Article

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