Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling

Science

Volumn 298, Issue 5599, 2002, Pages 1793-1796

  Bracey, Michael H ^a   Hanson, Michael A ^a   Masuda, Kim R ^a   Stevens, Raymond C ^a   Cravatt, Benjamin F ^a,b  

^a Department of Cell Biology ^*  (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CELL MEMBRANES; CRYSTAL STRUCTURE; FATTY ACIDS; HORMONES; LIPIDS; NEUROLOGY;

STRUCTURAL ADAPTATIONS;

ENZYMES;

AMINO ACID; CANNABINOID; FATTY ACID AMIDASE; LIPID; MEMBRANE PROTEIN; MONOAMINE DERIVATIVE; PEPTIDE HORMONE;

ADAPTATION; ENZYME; SIGNALING;

ARTICLE; BILAYER MEMBRANE; CANNABIS ADDICTION; CELL COMMUNICATION; CENTRAL NERVOUS SYSTEM FUNCTION; CRYSTAL STRUCTURE; DRUG BINDING; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; LIPID MEMBRANE; MEMBRANE STRUCTURE; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENDOCANNABINOIDS; HELIX-TURN-HELIX MOTIFS; LIPID BILAYERS; MODELS, MOLECULAR; PHOSPHONIC ACIDS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SOLUBILITY;

CANNABIS;

EID: 2242490907     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1076535     Document Type: Article

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