Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 43, 2005, Pages 15429-15434

  Blair, David E ^a   Schüttelkopf, Alexander W ^a   MacRae, James I ^a   Van Aalten, Daan M F ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Crystal structure; Metalloenzyme

Indexed keywords

ACYLTRANSFERASE; HISTIDYLHISTIDYLASPARTIC ACID; LYSOZYME; PEPTIDOGLYCAN; PEPTIDOGLYCAN DEACETYLASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL CELL WALL; BACTERIAL VIRULENCE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE DELETION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ANALYSIS;

AMIDOHYDROLASES; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; VIRULENCE FACTORS; ZINC;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS PNEUMONIAE;

EID: 27344441825     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504339102     Document Type: Article

References (27)

1. Boneca, I. G. (2005) Curr. Opin. Microbiol. 8, 46-53.
2. Severin, A., Tabei, K. & Tomasz, A. (2004) Microb. Drug Resist.-Mechan. Epidemiol. Dis. 10, 77-82.
3. Bera, A., Herbert, S., Jakob, A., Vollmer, W. & Gotz, F. (2005) Mol. Microbiol. 55, 778-787.
4. Vollmer, W. & Tomasz, A. (2000) J. Biol. Chem. 275, 20496-20501.
5. Vollmer, W. & Tomasz, A. (2002) Infect. Immun. 70, 7176-7178.
6. Caufrier, F., Martinou, A., Dupont, C. & Bouriotis, V. (2003) Carbohydr. Res. 338, 687-692.
7. Long, S. R. (1989) Cell 56, 203-214.
8. Kafetzopoulos, D., Thireos, G., Vournakis, J. N. & Bouriotis, V. (1993) Proc. Nalt. Acad. Sci. USA 90, 8005-8008.
9. Martinou, A., Koutsioulis, D. & Bouriotis, V. (2002) Protein Expr. Purif. 24, 111-116.
10. Hekmat, O., Tokuyasu, K. & Withers, S. G. (2003) Biochem. J. 374, 369-380.
11. Blair, D. E. & van Aalten, D. M. F. (2004) FEBS Lett. 570, 13-19.
12. Fukushima, T., Kitajima, T. & Sekiguchi, J. (2005) J. Bacteriol. 187, 1287-1292.
13. Leatherbarrow, R. J. (2001) GRAFIT (Erithacus Software, Horley, U.K.), Ver. 5.
14. Otwinowski, Z. & Minor, W. (1997) Methods Enzymol. 276, 307-326.
15. Sheldrick, G. M. & Schneider, T. R. (1997) Methods Enzymol. 277, 319-343.
16. Perrakis, A., Morris, R. & Lamzin, V. S. (1999) Nat. Struct. Biol. 6, 458-463.
17. Brunger, A. T., Adams, P. D., Clore, G. M., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., et al. (1998) Acta Crystallogr. D 54, 905-921.
18. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997) Acta Crystallogr. D 53, 240-255.
19. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
20. Emsley, P. & Cowtan, K. (2004) Acta Crystallogr. D 60, 2126-2132.
21. Schuettelkopf, A. W. & van Aalten, D. M. F. (2004) Acta Crystallogr. D 60, 1355-1363.
22. Whittington, D. A., Rusche, K. M., Shin, H., Fierke, C. A. & Christianson, D. W. (2003) Proc. Natl. Acad. Sci. USA 100, 8146-8150.
23. Hernick, M. & Fierke, C. A. (2005) Arch. Biochem. Biophys. 433, 71-84.
24. Coggins, B. E., Li, X. C., McClerren, A. L., Hindsgaul, O., Raetz, C. R. H. & Zhou, P. (2003) Nat. Struct. Biol. 10, 645-651.
25. McCarthy, A. A., Peterson, N. A., Knijff, R. & Baker, E. N. (2004) J. Mol. Biol. 335, 1131-1141.
26. Jackman, J. E., Fierke, C. A., Tumey, L. N., Pirrung, M., Uchiyama, T., Tahir, S. H., Hindsgaul, O. & Raetz, C. R. H. (2000) J. Biol. Chem. 275, 11002-11009.
27. Bond, C. S. (2003) Bioinformatics 19, 311-312.