The structure- and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1,6-N-acetyl- D-glucosamine

Journal of Biological Chemistry

Volumn 287, Issue 37, 2012, Pages 31126-31137

  Little, Dustin J ^a,b   Poloczek, Joanna ^c   Whitney, John C ^a,b   Robinson, Howard ^d   Nitz, Mark ^c   Howell, P Lynne ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC CONDITION; ANAEROBIC CONDITIONS; ASPARTIC ACIDS; BIOFILM FORMATION; CARBOHYDRATE ESTERASE; E. COLI; EXOPOLYSACCHARIDES; GLYCOSIDE HYDROLASES; IN-VIVO; INHIBITOR DESIGN; LOW LEVEL; MOLECULAR BASIS; PERIPLASMIC PROTEINS; SUBSTRATE SPECIFICITY;

AMINO ACIDS; BACTERIA; BIOFILMS; CARBOHYDRATES; ESCHERICHIA COLI; METABOLITES; OLIGOMERS;

ACETYLATION;

ADHESIN; ASPARTIC ACID; BACTERIAL ENZYME; CARBOHYDRATE ESTERASE; COBALT; ESTERASE; EXOPOLYSACCHARIDE; FERROUS ION; GLUCOSAMINE DERIVATIVE; GLYCOSIDASE; NICKEL; OLIGOMER; POLY BETA 1,6 N ACETYL DEXTRO GLUCOSAMINE; PROTEIN PGAB; UNCLASSIFIED DRUG; ZINC ION;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOFILM; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DEACETYLATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; IN VIVO STUDY; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION;

ACETYLATION; AMIDOHYDROLASES; BETA-GLUCANS; BIOFILMS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IRON; NICKEL; PROTEIN STRUCTURE, TERTIARY;

ESCHERICHIA COLI;

EID: 84865222416     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.390005     Document Type: Article

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