-
1
-
-
0035188740
-
Behaviour of crohn's disease according to the vienna classification: Changing pattern over the course of the disease
-
Louis E, Collard A, Oger AF, Degroote E, Aboul Nasr El Yafi FA, Belaiche J: Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease. Gut 2001; 49: 777-782.
-
(2001)
Gut
, vol.49
, pp. 777-782
-
-
Louis, E.1
Collard, A.2
Oger, A.F.3
Degroote, E.4
Aboul Nasr El Yafi, F.A.5
Belaiche, J.6
-
3
-
-
0021864017
-
Long-term follow-up of patients with crohn's disease. Relationship between the clinical pattern and prognosis
-
Farmer RG, Whelan G, Fazio VW: Long-term follow-up of patients with Crohn's disease. Relationship between the clinical pattern and prognosis. Gastroenterology 1985; 88: 1818-1825.
-
(1985)
Gastroenterology
, vol.88
, pp. 1818-1825
-
-
Farmer, R.G.1
Whelan, G.2
Fazio, V.W.3
-
4
-
-
0033053631
-
Epidemiology and the natural course of inflammatory bowel disease
-
vii
-
Andres PG, Friedman LS: Epidemiology and the natural course of inflammatory bowel disease. Gastroenterol Clin North Am 1999; 28: 255-281, vii.
-
(1999)
Gastroenterol Clin North Am
, vol.28
, pp. 255-281
-
-
Andres, P.G.1
Friedman, L.S.2
-
5
-
-
84878022371
-
Penetrating or stricturing diseases are the major determinants of time to first and repeat resection surgery in crohn's disease
-
Pittet V, Rogler G, Michetti P, Fournier N, Vader JP, Schoepfer A, Mottet C, Burnand B, Froehlich F; Swiss Inflammatory Bowel Disease Cohort Study G: Penetrating or stricturing diseases are the major determinants of time to first and repeat resection surgery in Crohn's disease. Digestion 2013; 87: 212-221.
-
(2013)
Digestion
, vol.87
, pp. 212-221
-
-
Swiss Inflammatory Bowel Disease Cohort Study G1
Pittet, V.2
Rogler, G.3
Michetti, P.4
Fournier, N.5
Vader, J.P.6
Schoepfer, A.7
Mottet, C.8
Burnand, B.9
Froehlich, F.10
-
6
-
-
79955844087
-
Development of the crohn's disease digestive damage score, the lemann score
-
Pariente B, Cosnes J, Danese S, et al: Development of the Crohn's disease digestive damage score, the Lemann score. Inflamm Bowel Dis 2011; 17: 1415-1422.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1415-1422
-
-
Pariente, B.1
Cosnes, J.2
Danese, S.3
-
7
-
-
84908254651
-
Results of the 4th scientific workshop of the ecco (i): Pathophysiology of intestinal fibrosis in ibd
-
Epub ahead of print
-
Latella G, Rogler G, Bamias G, Breynaert C, Florholmen J, Pellino G, Reif S, Speca S, Lawrance IC: Results of the 4th scientific workshop of the ECCO (I): pathophysiology of intestinal fibrosis in IBD. J Crohns Colitis 2014, Epub ahead of print.
-
(2014)
J Crohns Colitis
-
-
Latella, G.1
Rogler, G.2
Bamias, G.3
Breynaert, C.4
Florholmen, J.5
Pellino, G.6
Reif, S.7
Speca, S.8
Lawrance, I.C.9
-
8
-
-
84908227294
-
Results of the 4th scientific workshop of the ecco (group ii): Markers of intestinal fibrosis in inflammatory bowel disease
-
Epub ahead of print
-
Rieder F, de Bruyn JR, Pham BT, Katsanos K, Annese V, Higgins PD, Magro F, Dotan I: Results of the 4th Scientific Workshop of the ECCO (Group II): markers of intestinal fibrosis in inflammatory bowel disease. J Crohns Colitis 2014, Epub ahead of print.
-
(2014)
J Crohns Colitis
-
-
Rieder, F.1
De Bruyn, J.R.2
Pham, B.T.3
Katsanos, K.4
Annese, V.5
Higgins, P.D.6
Magro, F.7
Dotan, I.8
-
10
-
-
84904046300
-
Review article: The efficacy of biomarkers in chronic fibroproliferative diseases - Early diagnosis and prognosis, with liver fibrosis as an exemplar
-
Karsdal MA, Krarup H, Sand JM, Christensen PB, Gerstoft J, Leeming DJ, Weis N, Schaffalitzky de Muckadell OB, Krag A: Review article: the efficacy of biomarkers in chronic fibroproliferative diseases - early diagnosis and prognosis, with liver fibrosis as an exemplar. Aliment Pharmacol Ther 2014; 40: 233-249.
-
(2014)
Aliment Pharmacol Ther
, vol.40
, pp. 233-249
-
-
Karsdal, M.A.1
Krarup, H.2
Sand, J.M.3
Christensen, P.B.4
Gerstoft, J.5
Leeming, D.J.6
Weis, N.7
Schaffalitzky De Muckadell, O.B.8
Krag, A.9
-
11
-
-
84902675168
-
Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update
-
Elpek GO: Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: an update. World J Gastroenterol 2014; 20: 7260-7276.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 7260-7276
-
-
Elpek, G.O.1
-
12
-
-
84877141184
-
Evolving therapies for liver fibrosis
-
Schuppan D, Kim YO: Evolving therapies for liver fibrosis. J Clin Invest 2013; 123: 1887-1901.
-
(2013)
J Clin Invest
, vol.123
, pp. 1887-1901
-
-
Schuppan, D.1
Kim, Y.O.2
-
13
-
-
84870951352
-
Role of sonic hedgehog in idiopathic pulmonary fibrosis
-
Bolanos AL, Milla CM, Lira JC, Ramirez R, Checa M, Barrera L, Garcia-Alvarez J, Carbajal V, Becerril C, Gaxiola M, Pardo A, Selman M: Role of sonic Hedgehog in idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2012; 303:L978-L990.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
, pp. L978-L990
-
-
Bolanos, A.L.1
Milla, C.M.2
Lira, J.C.3
Ramirez, R.4
Checa, M.5
Barrera, L.6
Garcia-Alvarez, J.7
Carbajal, V.8
Becerril, C.9
Gaxiola, M.10
Pardo, A.11
Selman, M.12
-
14
-
-
84906264574
-
Hedgehog signaling pathway as key player in liver fibrosis: New insights and perspectives
-
Yang JJ, Tao H, Li J: Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives. Expert Opin Ther Targets 2014; 18: 1011-1021.
-
(2014)
Expert Opin Ther Targets
, vol.18
, pp. 1011-1021
-
-
Yang, J.J.1
Tao, H.2
Li, J.3
-
16
-
-
79251639838
-
Therapeutic effect of a peptide inhibitor of tgf-beta on pulmonary fibrosis
-
Arribillaga L, Dotor J, Basagoiti M, Riezu-Boj JI, Borras-Cuesta F, Lasarte JJ, Sarobe P, Cornet ME, Feijoo E: Therapeutic effect of a peptide inhibitor of TGF-beta on pulmonary fibrosis. Cytokine 2011; 53: 327-333.
-
(2011)
Cytokine
, vol.53
, pp. 327-333
-
-
Arribillaga, L.1
Dotor, J.2
Basagoiti, M.3
Riezu-Boj, J.I.4
Borras-Cuesta, F.5
Lasarte, J.J.6
Sarobe, P.7
Cornet, M.E.8
Feijoo, E.9
-
17
-
-
19944421105
-
Inhibition of tgf-beta signaling by an alk5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis
-
de Gouville AC, Boullay V, Krysa G, Pilot J, Brusq JM, Loriolle F, Gauthier JM, Papworth SA, Laroze A, Gellibert F, Huet S: Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis. Br J Pharmacol 2005; 145: 166-177.
-
(2005)
Br J Pharmacol
, vol.145
, pp. 166-177
-
-
De Gouville, A.C.1
Boullay, V.2
Krysa, G.3
Pilot, J.4
Brusq, J.M.5
Loriolle, F.6
Gauthier, J.M.7
Papworth, S.A.8
Laroze, A.9
Gellibert, F.10
Huet, S.11
-
18
-
-
42249113861
-
SM16, an orally active tgf-beta type i receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model
-
Fu K, Corbley MJ, Sun L, et al: SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model. Arterioscl Thromb Vasc Biol 2008; 28: 665-671.
-
(2008)
Arterioscl Thromb Vasc Biol
, vol.28
, pp. 665-671
-
-
Fu, K.1
Corbley, M.J.2
Sun, L.3
-
19
-
-
84860390569
-
Inhibition of pdgf, tgf-beta, and abl signaling and reduction of liver fibrosis by the small molecule bcr-abl tyrosine kinase antagonist nilotinib
-
Liu Y, Wang Z, Kwong SQ, Lui EL, Friedman SL, Li FR, Lam RW, Zhang GC, Zhang H, Ye T: Inhibition of PDGF, TGF-beta, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. J Hepatol 2011; 55: 612-625.
-
(2011)
J Hepatol
, vol.55
, pp. 612-625
-
-
Liu, Y.1
Wang, Z.2
Kwong, S.Q.3
Lui, E.L.4
Friedman, S.L.5
Li, F.R.6
Lam, R.W.7
Zhang, G.C.8
Zhang, H.9
Ye, T.10
-
20
-
-
79956294234
-
Hepatocyte growth factor attenuates renal fibrosis through tgf-β1 suppression by apoptosis of myofibroblasts
-
Iekushi K, Taniyama Y, Azuma J, Sanada F, Kusunoki H, Yokoi T, Koibuchi N, Okayama K, Rakugi H, Morishita R: Hepatocyte growth factor attenuates renal fibrosis through TGF-β1 suppression by apoptosis of myofibroblasts. J Hypertens 2010; 28: 2454-2461.
-
(2010)
J Hypertens
, vol.28
, pp. 2454-2461
-
-
Iekushi, K.1
Taniyama, Y.2
Azuma, J.3
Sanada, F.4
Kusunoki, H.5
Yokoi, T.6
Koibuchi, N.7
Okayama, K.8
Rakugi, H.9
Morishita, R.10
-
21
-
-
77950608186
-
Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
-
Moreno M, Gonzalo T, Kok RJ, et al: Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology 2010; 51: 942-952.
-
(2010)
Hepatology
, vol.51
, pp. 942-952
-
-
Moreno, M.1
Gonzalo, T.2
Kok, R.J.3
-
22
-
-
56649106258
-
Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model
-
Kim MY, Baik SK, Park DH, Jang YO, Suk KT, Yea CJ, Lee IY, Kim JW, Kim HS, Kwon SO, Cho MY, Ko SB, Chang SJ, Um SH, Han KH: Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model. J Gastroenterol 2008; 43: 889-896.
-
(2008)
J Gastroenterol
, vol.43
, pp. 889-896
-
-
Kim, M.Y.1
Baik, S.K.2
Park, D.H.3
Jang, Y.O.4
Suk, K.T.5
Yea, C.J.6
Lee, I.Y.7
Kim, J.W.8
Kim, H.S.9
Kwon, S.O.10
Cho, M.Y.11
Ko, S.B.12
Chang, S.J.13
Um, S.H.14
Han, K.H.15
-
23
-
-
15844390050
-
Combined effect of an ace inhibitor, perindopril, and interferon on liver fibrosis markers in patients with chronic hepatitis c
-
Yoshiji H, Noguchi R, Fukui H: Combined effect of an ACE inhibitor, perindopril, and interferon on liver fibrosis markers in patients with chronic hepatitis C. J Gastroenterol 2005; 40: 215-216.
-
(2005)
J Gastroenterol
, vol.40
, pp. 215-216
-
-
Yoshiji, H.1
Noguchi, R.2
Fukui, H.3
-
24
-
-
33746265975
-
Inhibition of connective tissue growth factor by sirna prevents liver fibrosis in rats
-
Li G, Xie Q, Shi Y, Li D, Zhang M, Jiang S, Zhou H, Lu H, Jin Y: Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. J Gene Med 2006; 8: 889-900.
-
(2006)
J Gene Med
, vol.8
, pp. 889-900
-
-
Li, G.1
Xie, Q.2
Shi, Y.3
Li, D.4
Zhang, M.5
Jiang, S.6
Zhou, H.7
Lu, H.8
Jin, Y.9
-
25
-
-
0036087126
-
Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis
-
Yokoi H, Mukoyama M, Sugawara A, Mori K, Nagae T, Makino H, Suganami T, Yahata K, Fujinaga Y, Tanaka I, Nakao K: Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis. Am J Physiol Renal Physiol 2002; 282:F933-F942.
-
(2002)
Am J Physiol Renal Physiol
, vol.282
, pp. F933-F942
-
-
Yokoi, H.1
Mukoyama, M.2
Sugawara, A.3
Mori, K.4
Nagae, T.5
Makino, H.6
Suganami, T.7
Yahata, K.8
Fujinaga, Y.9
Tanaka, I.10
Nakao, K.11
-
26
-
-
84893953769
-
The peripheral cannabinoid receptor 1 antagonist vd60 efficiently inhibits carbon tetrachloride-intoxicated hepatic fibrosis progression
-
Wei Y, Kang XL, Wang X: The peripheral cannabinoid receptor 1 antagonist VD60 efficiently inhibits carbon tetrachloride-intoxicated hepatic fibrosis progression. Exp Biol Med (Maywood) 2014; 239: 183-192.
-
(2014)
Exp Biol Med (Maywood)
, vol.239
, pp. 183-192
-
-
Wei, Y.1
Kang, X.L.2
Wang, X.3
-
27
-
-
82855164046
-
Cannabinoid receptor type i modulates alcohol- induced liver fibrosis
-
Patsenker E, Stoll M, Millonig G, Agaimy A, Wissniowski T, Schneider V, Mueller S, Brenneisen R, Seitz HK, Ocker M, Stickel F: Cannabinoid receptor type I modulates alcohol- induced liver fibrosis. Mol Med 2011; 17: 1285-1294.
-
(2011)
Mol Med
, vol.17
, pp. 1285-1294
-
-
Patsenker, E.1
Stoll, M.2
Millonig, G.3
Agaimy, A.4
Wissniowski, T.5
Schneider, V.6
Mueller, S.7
Brenneisen, R.8
Seitz, H.K.9
Ocker, M.10
Stickel, F.11
-
28
-
-
33847733156
-
CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
-
Wasmuth HE, Trautwein C: CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis. Hepatology 2007; 45: 543-544.
-
(2007)
Hepatology
, vol.45
, pp. 543-544
-
-
Wasmuth, H.E.1
Trautwein, C.2
-
29
-
-
79953671113
-
Lysophosphatidic acid-1-receptor targeting agents for fibrosis
-
Rancoule C, Pradere JP, Gonzalez J, Klein J, Valet P, Bascands JL, Schanstra JP, Saulnier-Blache JS: Lysophosphatidic acid-1-receptor targeting agents for fibrosis. Expert Opin Investig Drugs 2011; 20: 657-667.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 657-667
-
-
Rancoule, C.1
Pradere, J.P.2
Gonzalez, J.3
Klein, J.4
Valet, P.5
Bascands, J.L.6
Schanstra, J.P.7
Saulnier-Blache, J.S.8
-
30
-
-
38049091636
-
The lysophosphatidic acid receptor lpa1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
-
Tager AM, LaCamera P, Shea BS, et al: The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med 2008; 14: 45-54.
-
(2008)
Nat Med
, vol.14
, pp. 45-54
-
-
Tager, A.M.1
Lacamera, P.2
Shea, B.S.3
-
31
-
-
84877066766
-
Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
-
Iredale JP, Thompson A, Henderson NC: Extracellular matrix degradation in liver fibrosis: biochemistry and regulation. Biochim Biophys Acta 2013; 1832: 876-883.
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 876-883
-
-
Iredale, J.P.1
Thompson, A.2
Henderson, N.C.3
-
32
-
-
0030453783
-
Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo
-
Unemori EN, Pickford LB, Salles AL, Piercy CE, Grove BH, Erikson ME, Amento EP: Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J Clin Invest 1996; 98: 2739-2745.
-
(1996)
J Clin Invest
, vol.98
, pp. 2739-2745
-
-
Unemori, E.N.1
Pickford, L.B.2
Salles, A.L.3
Piercy, C.E.4
Grove, B.H.5
Erikson, M.E.6
Amento, E.P.7
-
33
-
-
34047121535
-
Expression of mmps and timps in liver fibrosis - A systematic review with special emphasis on anti-fibrotic strategies
-
Hemmann S, Graf J, Roderfeld M, Roeb E: Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies. J Hepatol 2007; 46: 955-975.
-
(2007)
J Hepatol
, vol.46
, pp. 955-975
-
-
Hemmann, S.1
Graf, J.2
Roderfeld, M.3
Roeb, E.4
-
34
-
-
0025121968
-
Synthesis of lysyl oxidase in experimental hepatic fibrosis
-
Wakasaki H, Ooshima A: Synthesis of lysyl oxidase in experimental hepatic fibrosis. Biochem Biophys Res Commun 1990; 166: 1201-1204.
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 1201-1204
-
-
Wakasaki, H.1
Ooshima, A.2
-
36
-
-
84870487825
-
Emerging role of the interleukin (il)-33/st2 axis in gut mucosal wound healing and fibrosis
-
Lopetuso LR, Scaldaferri F, Pizarro TT: Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis. Fibrogenesis Tissue Repair 2012; 5: 18.
-
(2012)
Fibrogenesis Tissue Repair
, vol.5
, pp. 18
-
-
Lopetuso, L.R.1
Scaldaferri, F.2
Pizarro, T.T.3
-
37
-
-
80054861647
-
SAMP1/yitfc mouse strain: A spontaneous model of crohn's disease-like ileitis
-
Pizarro TT, Pastorelli L, Bamias G, Garg RR, Reuter BK, Mercado JR, Chieppa M, Arseneau KO, Ley K, Cominelli F: SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis. Inflamm Bowel Dis 2011; 17: 2566-2584.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 2566-2584
-
-
Pizarro, T.T.1
Pastorelli, L.2
Bamias, G.3
Garg, R.R.4
Reuter, B.K.5
Mercado, J.R.6
Chieppa, M.7
Arseneau, K.O.8
Ley, K.9
Cominelli, F.10
-
38
-
-
84871410101
-
Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium
-
Yamaguchi H, Suzuki K, Nagata M, et al: Irsogladine maleate ameliorates inflammation and fibrosis in mice with chronic colitis induced by dextran sulfate sodium. Med Mol Morphol 2012; 45: 140-151.
-
(2012)
Med Mol Morphol
, vol.45
, pp. 140-151
-
-
Yamaguchi, H.1
Suzuki, K.2
Nagata, M.3
-
39
-
-
84864557487
-
Mucosal healing and fibrosis after acute or chronic inflammation in wild type fvb-n mice and c57bl6 procollagen α1(i)-promoter-gfp reporter mice
-
Ding S, Walton KL, Blue RE, McNaughton K, Magness ST, Lund PK: Mucosal healing and fibrosis after acute or chronic inflammation in wild type FVB-N mice and C57Bl6 procollagen α1(I)-promoter-GFP reporter mice. PloS One 2012; 7:e42568.
-
(2012)
PloS One
, vol.7
-
-
Ding, S.1
Walton, K.L.2
Blue, R.E.3
McNaughton, K.4
Magness, S.T.5
Lund, P.K.6
-
40
-
-
79952780231
-
Analysis of intestinal fibrosis in chronic colitis in mice induced by dextran sulfate sodium
-
Suzuki K, Sun X, Nagata M, Kawase T, Yamaguchi H, Sukumaran V, Kawauchi Y, Kawachi H, Nishino T, Watanabe K, Yoneyama H, Asakura H: Analysis of intestinal fibrosis in chronic colitis in mice induced by dextran sulfate sodium. Pathol Int 2011; 61: 228-238.
-
(2011)
Pathol Int
, vol.61
, pp. 228-238
-
-
Suzuki, K.1
Sun, X.2
Nagata, M.3
Kawase, T.4
Yamaguchi, H.5
Sukumaran, V.6
Kawauchi, Y.7
Kawachi, H.8
Nishino, T.9
Watanabe, K.10
Yoneyama, H.11
Asakura, H.12
-
41
-
-
84863860108
-
Dynamic progress of 2,4,6-trinitrobenzene sulfonic acid induced chronic colitis and fibrosis in rat model
-
Zhu MY, Lu YM, Ou YX, Zhang HZ, Chen WX: Dynamic progress of 2,4,6-trinitrobenzene sulfonic acid induced chronic colitis and fibrosis in rat model. J Dig Dis 2012; 13: 421-429.
-
(2012)
J Dig Dis
, vol.13
, pp. 421-429
-
-
Zhu, M.Y.1
Lu, Y.M.2
Ou, Y.X.3
Zhang, H.Z.4
Chen, W.X.5
-
42
-
-
84856403018
-
Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats
-
Wengrower D, Zanninelli G, Latella G, Necozione S, Metanes I, Israeli E, Lysy J, Pines M, Papo O, Goldin E: Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats. Can J Gastroenterol 2012; 26: 33-39.
-
(2012)
Can J Gastroenterol
, vol.26
, pp. 33-39
-
-
Wengrower, D.1
Zanninelli, G.2
Latella, G.3
Necozione, S.4
Metanes, I.5
Israeli, E.6
Lysy, J.7
Pines, M.8
Papo, O.9
Goldin, E.10
-
43
-
-
80052130352
-
Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with crohn's disease
-
Stidham RW, Xu J, Johnson LA, Kim K, Moons DS, McKenna BJ, Rubin JM, Higgins PD: Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease. Gastroenterology 2011; 141: 819-826.e1.
-
(2011)
Gastroenterology
, vol.141
, pp. 819-819e1
-
-
Stidham, R.W.1
Xu, J.2
Johnson, L.A.3
Kim, K.4
Moons, D.S.5
McKenna, B.J.6
Rubin, J.M.7
Higgins, P.D.8
-
44
-
-
79957583692
-
The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the tnbs model of colitis
-
Peterson TC, Peterson MR, Raoul JM: The effect of pentoxifylline and its metabolite-1 on inflammation and fibrosis in the TNBS model of colitis. Eur J Pharmacol 2011; 662: 47-54.
-
(2011)
Eur J Pharmacol
, vol.662
, pp. 47-54
-
-
Peterson, T.C.1
Peterson, M.R.2
Raoul, J.M.3
-
45
-
-
78149348825
-
Substance p modulates colitisassociated fibrosis
-
Koon HW, Shih D, Karagiannides I, Zhao D, Fazelbhoy Z, Hing T, Xu H, Lu B, Gerard N, Pothoulakis C: Substance p modulates colitisassociated fibrosis. Am J Pathol 2010; 177: 2300-2309.
-
(2010)
Am J Pathol
, vol.177
, pp. 2300-2309
-
-
Koon, H.W.1
Shih, D.2
Karagiannides, I.3
Zhao, D.4
Fazelbhoy, Z.5
Hing, T.6
Xu, H.7
Lu, B.8
Gerard, N.9
Pothoulakis, C.10
-
46
-
-
79951618861
-
Amelioration of excess collagen iαi, fibrosis, and smooth muscle growth in tnbs-induced colitis in igf-i(+/-) mice
-
Mahavadi S, Flynn RS, Grider JR, Qiao LY, Murthy KS, Hazelgrove KB, Kuemmerle JF: Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice. Inflamm Bowel Dis 2011; 17: 711-719.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 711-719
-
-
Mahavadi, S.1
Flynn, R.S.2
Grider, J.R.3
Qiao, L.Y.4
Murthy, K.S.5
Hazelgrove, K.B.6
Kuemmerle, J.F.7
-
47
-
-
77953769774
-
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis
-
Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R: Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem 2010; 285: 20202-20212.
-
(2010)
J Biol Chem
, vol.285
, pp. 20202-20212
-
-
Flier, S.N.1
Tanjore, H.2
Kokkotou, E.G.3
Sugimoto, H.4
Zeisberg, M.5
Kalluri, R.6
-
48
-
-
77952678563
-
Targeting tgf-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis
-
Ma Y, Guan Q, Bai A, Weiss CR, Hillman CL, Ma A, Zhou G, Qing G, Peng Z: Targeting TGF-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis. Inflamm Bowel Dis 2010; 16: 1040-1050.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1040-1050
-
-
Ma, Y.1
Guan, Q.2
Bai, A.3
Weiss, C.R.4
Hillman, C.L.5
Ma, A.6
Zhou, G.7
Qing, G.8
Peng, Z.9
-
49
-
-
84876388451
-
Anti-tumor necrosis factor α prevents bowel fibrosis assessed by messenger rna, histology, and magnetization transfer mri in rats with crohn's disease
-
Adler J, Rahal K, Swanson SD, Schmiedlin-Ren P, Rittershaus AC, Reingold LJ, Brudi JS, Shealy D, Cai A, McKenna BJ, Zimmermann EM: Anti-tumor necrosis factor α prevents bowel fibrosis assessed by messenger RNA, histology, and magnetization transfer MRI in rats with Crohn's disease. Inflamm Bowel Dis 2013; 19: 683-690.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 683-690
-
-
Adler, J.1
Rahal, K.2
Swanson, S.D.3
Schmiedlin-Ren, P.4
Rittershaus, A.C.5
Reingold, L.J.6
Brudi, J.S.7
Shealy, D.8
Cai, A.9
McKenna, B.J.10
Zimmermann, E.M.11
-
50
-
-
79953000413
-
Magnetization transfer helps detect intestinal fibrosis in an animal model of crohn disease
-
Adler J, Swanson SD, Schmiedlin-Ren P, Higgins PD, Golembeski CP, Polydorides AD, McKenna BJ, Hussain HK, Verrot TM, Zimmermann EM: Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology 2011; 259: 127-135.
-
(2011)
Radiology
, vol.259
, pp. 127-135
-
-
Adler, J.1
Swanson, S.D.2
Schmiedlin-Ren, P.3
Higgins, P.D.4
Golembeski, C.P.5
Polydorides, A.D.6
McKenna, B.J.7
Hussain, H.K.8
Verrot, T.M.9
Zimmermann, E.M.10
-
51
-
-
0037379778
-
Emergence of perianal fistulizing disease in the samp1/yitfc mouse, a spontaneous model of chronic ileitis
-
Rivera-Nieves J, Bamias G, Vidrich A, Marini M, Pizarro TT, McDuffie MJ, Moskaluk CA, Cohn SM, Cominelli F: Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis. Gastroenterology 2003; 124: 972-982.
-
(2003)
Gastroenterology
, vol.124
, pp. 972-982
-
-
Rivera-Nieves, J.1
Bamias, G.2
Vidrich, A.3
Marini, M.4
Pizarro, T.T.5
McDuffie, M.J.6
Moskaluk, C.A.7
Cohn, S.M.8
Cominelli, F.9
-
52
-
-
33846493766
-
Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis
-
Bamias G, Okazawa A, Rivera-Nieves J, Arseneau KO, De La Rue SA, Pizarro TT, Cominelli F: Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis. J Immunol 2007; 178: 1809-1818.
-
(2007)
J Immunol
, vol.178
, pp. 1809-1818
-
-
Bamias, G.1
Okazawa, A.2
Rivera-Nieves, J.3
Arseneau, K.O.4
De La Rue, S.A.5
Pizarro, T.T.6
Cominelli, F.7
-
53
-
-
84890880368
-
Heterotopic tracheal transplantation animal model of bronchiolitis obliterans: A reproducible model
-
Gomez-de-Antonio D, Campo-Canaveral de la Cruz JL, Gonzalez-Lois C, Santos M, Millan I, Varela de Ugarte A: Heterotopic tracheal transplantation animal model of bronchiolitis obliterans: a reproducible model. Ann Transplant 2013; 18: 661-670.
-
(2013)
Ann Transplant
, vol.18
, pp. 661-670
-
-
Gomez-De-Antonio, D.1
Campo-Canaveral De La Cruz, J.L.2
Gonzalez-Lois, C.3
Santos, M.4
Millan, I.5
Varela De Ugarte, A.6
-
54
-
-
84885955925
-
A relevant experimental model for human bronchiolitis obliterans syndrome
-
Atanasova S, Hirschburger M, Jonigk D, Obert M, Petri K, Evers A, Hecker A, Schmitz J, Kaufmann A, Wilhelm J, Chakraborty T, Warnecke G, Gottlieb J, Padberg W, Grau V: A relevant experimental model for human bronchiolitis obliterans syndrome. J Heart Lung Transplant 2013; 32: 1131-1139.
-
(2013)
J Heart Lung Transplant
, vol.32
, pp. 1131-1139
-
-
Atanasova, S.1
Hirschburger, M.2
Jonigk, D.3
Obert, M.4
Petri, K.5
Evers, A.6
Hecker, A.7
Schmitz, J.8
Kaufmann, A.9
Wilhelm, J.10
Chakraborty, T.11
Warnecke, G.12
Gottlieb, J.13
Padberg, W.14
Grau, V.15
-
55
-
-
37349073107
-
Recipient nod2/card15 variants: A novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation
-
Hildebrandt GC, Granell M, Urbano-Ispizua A, Wolff D, Hertenstein B, Greinix HT, Brenmoehl J, Schulz C, Dickinson AM, Hahn J, Rogler G, Andreesen R, Holler E: Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2008; 14: 67-74.
-
(2008)
Biol Blood Marrow Transplant
, vol.14
, pp. 67-74
-
-
Hildebrandt, G.C.1
Granell, M.2
Urbano-Ispizua, A.3
Wolff, D.4
Hertenstein, B.5
Greinix, H.T.6
Brenmoehl, J.7
Schulz, C.8
Dickinson, A.M.9
Hahn, J.10
Rogler, G.11
Andreesen, R.12
Holler, E.13
-
56
-
-
84888264489
-
A new heterotopic transplant animal model of intestinal fibrosis
-
Hausmann M, Rechsteiner T, Caj M, Benden C, Fried M, Boehler A, Rogler G: A new heterotopic transplant animal model of intestinal fibrosis. Inflamm Bowel Dis 2013; 19: 2302-2314.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 2302-2314
-
-
Hausmann, M.1
Rechsteiner, T.2
Caj, M.3
Benden, C.4
Fried, M.5
Boehler, A.6
Rogler, G.7
-
57
-
-
84896547253
-
The significance of ykl-40 protein in liver fibrosis
-
Tao H, Yang JJ, Shi KH, Huang C, Zhang L, Lv XW, Li J: The significance of YKL-40 protein in liver fibrosis. Inflamm Res 2014; 63: 249-254.
-
(2014)
Inflamm Res
, vol.63
, pp. 249-254
-
-
Tao, H.1
Yang, J.J.2
Shi, K.H.3
Huang, C.4
Zhang, L.5
Lv, X.W.6
Li, J.7
-
58
-
-
48549087887
-
Serum ykl-40 as a marker of disease activity and stricture formation in patients with crohn's disease
-
Erzin Y, Uzun H, Karatas A, Celik AF: Serum YKL-40 as a marker of disease activity and stricture formation in patients with Crohn's disease. J Gastroenterol Hepatol 2008; 23:e357-e362.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. e357-e362
-
-
Erzin, Y.1
Uzun, H.2
Karatas, A.3
Celik, A.F.4
-
59
-
-
84879071255
-
Magnetization transfer for the assessment of bowel fibrosis in patients with crohn's disease: Initial experience
-
Pazahr S, Blume I, Frei P, Chuck N, Nanz D, Rogler G, Patak M, Boss A: Magnetization transfer for the assessment of bowel fibrosis in patients with Crohn's disease: initial experience. MAGMA 2013; 26: 291-301.
-
(2013)
MAGMA
, vol.26
, pp. 291-301
-
-
Pazahr, S.1
Blume, I.2
Frei, P.3
Chuck, N.4
Nanz, D.5
Rogler, G.6
Patak, M.7
Boss, A.8
-
60
-
-
84886928792
-
Update of liver fibrosis and steatosis with transient elastography (fibroscan)
-
Wong GL: Update of liver fibrosis and steatosis with transient elastography (Fibroscan). Gastroenterol Rep (Oxf) 2013; 1: 19-26.
-
(2013)
Gastroenterol Rep (Oxf)
, vol.1
, pp. 19-26
-
-
Wong, G.L.1
-
61
-
-
84880649809
-
Advanced fibrosis in nonalcoholic fatty liver disease: Noninvasive assessment with mr elastography
-
Kim D, Kim WR, Talwalkar JA, Kim HJ, Ehman RL: Advanced fibrosis in nonalcoholic fatty liver disease: noninvasive assessment with MR elastography. Radiology 2013; 268: 411-419.
-
(2013)
Radiology
, vol.268
, pp. 411-419
-
-
Kim, D.1
Kim, W.R.2
Talwalkar, J.A.3
Kim, H.J.4
Ehman, R.L.5
-
62
-
-
37349090047
-
Noninvasive assessment of liver fibrosis and portal hypertension with transient elastography
-
Rockey DC: Noninvasive assessment of liver fibrosis and portal hypertension with transient elastography. Gastroenterology 2008; 134: 8-14.
-
(2008)
Gastroenterology
, vol.134
, pp. 8-14
-
-
Rockey, D.C.1
-
63
-
-
39049101883
-
Technology insight: Noninvasive assessment of liver fibrosis by biochemical scores and elastography
-
Pinzani M, Vizzutti F, Arena U, Marra F: Technology insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography. Nat Clin Pract Gastroenterol Hepatol 2008; 5: 95-106.
-
(2008)
Nat Clin Pract Gastroenterol Hepatol
, vol.5
, pp. 95-106
-
-
Pinzani, M.1
Vizzutti, F.2
Arena, U.3
Marra, F.4
-
64
-
-
41349094999
-
Performance of transient elastography for the staging of liver fibrosis: A meta-analysis
-
Friedrich-Rust M, Ong MF, Martens S, Sarrazin C, Bojunga J, Zeuzem S, Herrmann E: Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology 2008; 134: 960-974.
-
(2008)
Gastroenterology
, vol.134
, pp. 960-974
-
-
Friedrich-Rust, M.1
Ong, M.F.2
Martens, S.3
Sarrazin, C.4
Bojunga, J.5
Zeuzem, S.6
Herrmann, E.7
-
65
-
-
33745388106
-
Non-invasive measurement of liver fibrosis: Application of the fibroscan in hepatology
-
Verveer C, de Knegt RJ: Non-invasive measurement of liver fibrosis: application of the FibroScan in hepatology. Scand J Gastroenterol Suppl 2006; 243: 85-88.
-
(2006)
Scand J Gastroenterol Suppl
, vol.243
, pp. 85-88
-
-
Verveer, C.1
De Knegt, R.J.2
-
66
-
-
84875208959
-
Forced vital capacity as a primary end point in idiopathic pulmonary fibrosis treatment trials: Making a silk purse from a sow's ear
-
Wells AU: Forced vital capacity as a primary end point in idiopathic pulmonary fibrosis treatment trials: Making a silk purse from a sow's ear. Thorax 2013; 68: 309-310.
-
(2013)
Thorax
, vol.68
, pp. 309-310
-
-
Wells, A.U.1
-
68
-
-
84904276966
-
Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications
-
Spagnolo P, Rossi G, Cavazza A: Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications. Exp Rev Clin Immunol 2014; 10: 1005-1017.
-
(2014)
Exp Rev Clin Immunol
, vol.10
, pp. 1005-1017
-
-
Spagnolo, P.1
Rossi, G.2
Cavazza, A.3
-
70
-
-
84873038964
-
Molecular mechanisms in progressive idiopathic pulmonary fibrosis
-
Steele MP, Schwartz DA: Molecular mechanisms in progressive idiopathic pulmonary fibrosis. Annu Rev Med 2013; 64: 265-276.
-
(2013)
Annu Rev Med
, vol.64
, pp. 265-276
-
-
Steele, M.P.1
Schwartz, D.A.2
-
71
-
-
77955881563
-
Diminished prostaglandin e 2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis
-
Maher TM, Evans IC, Bottoms SE, Mercer PF, Thorley AJ, Nicholson AG, Laurent GJ, Tetley TD, Chambers RC, McAnulty RJ: Diminished prostaglandin E 2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010; 182: 73-82.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 73-82
-
-
Maher, T.M.1
Evans, I.C.2
Bottoms, S.E.3
Mercer, P.F.4
Thorley, A.J.5
Nicholson, A.G.6
Laurent, G.J.7
Tetley, T.D.8
Chambers, R.C.9
McAnulty, R.J.10
-
72
-
-
0028924146
-
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin e 2 and to express cyclooxygenase-2
-
Wilborn J, Crofford LJ, Burdick MD, Kunkel SL, Strieter RM, Peters-Golden M: Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E 2 and to express cyclooxygenase-2. J Clin Invest 1995; 95: 1861-1868.
-
(1995)
J Clin Invest
, vol.95
, pp. 1861-1868
-
-
Wilborn, J.1
Crofford, L.J.2
Burdick, M.D.3
Kunkel, S.L.4
Strieter, R.M.5
Peters-Golden, M.6
-
73
-
-
84899746115
-
Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized scid idiopathic pulmonary fibrosis model
-
Murray LA, Zhang H, Oak SR, Coelho AL, Herath A, Flaherty KR, Lee J, Bell M, Knight DA, Martinez FJ, Sleeman MA, Herzog EL, Hogaboam CM: Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model. Am J Respir Cell Mol Biol 2014; 50: 985-994.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, pp. 985-994
-
-
Murray, L.A.1
Zhang, H.2
Oak, S.R.3
Coelho, A.L.4
Herath, A.5
Flaherty, K.R.6
Lee, J.7
Bell, M.8
Knight, D.A.9
Martinez, F.J.10
Sleeman, M.A.11
Herzog, E.L.12
Hogaboam, C.M.13
-
74
-
-
0029049791
-
Increased interleukin-1 receptor antagonist in idiopathic pulmonary fibrosis. A compartmental analysis
-
Smith DR, Kunkel SL, Standiford TJ, Rolfe MW, Lynch JP 3rd, Arenberg DA, Wilke CA, Burdick MD, Martinez FJ, Hampton JN, et al: Increased interleukin-1 receptor antagonist in idiopathic pulmonary fibrosis. A compartmental analysis. Am J Respir Crit Care Med 1995; 151: 1965-1973.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 1965-1973
-
-
Smith, D.R.1
Kunkel, S.L.2
Standiford, T.J.3
Rolfe, M.W.4
Lynch, J.P.5
Arenberg, D.A.6
Wilke, C.A.7
Burdick, M.D.8
Martinez, F.J.9
Hampton, J.N.10
-
75
-
-
84886779431
-
Expression of fibroblast growth factor 9 in normal human lung and idiopathic pulmonary fibrosis
-
Coffey E, Newman DR, Sannes PL: Expression of fibroblast growth factor 9 in normal human lung and idiopathic pulmonary fibrosis. J Histochem Cytochem 2013; 61: 671-679.
-
(2013)
J Histochem Cytochem
, vol.61
, pp. 671-679
-
-
Coffey, E.1
Newman, D.R.2
Sannes, P.L.3
-
77
-
-
84901759236
-
A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis
-
King TE Jr, Bradford WZ, Castro-Bernardini S, et al: A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. N Engl J Med 2014; 370: 2083-2092.
-
(2014)
N Engl J Med
, vol.370
, pp. 2083-2092
-
-
King, T.E.1
Bradford, W.Z.2
Castro-Bernardini, S.3
-
78
-
-
84897459884
-
All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials
-
King TE Jr, Albera C, Bradford WZ, Costabel U, du Bois RM, Leff JA, Nathan SD, Sahn SA, Valeyre D, Noble PW: All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials. Am J Respir Crit Care Med 2014; 189: 825-831.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 825-831
-
-
King, T.E.1
Albera, C.2
Bradford, W.Z.3
Costabel, U.4
Du Bois, R.M.5
Leff, J.A.6
Nathan, S.D.7
Sahn, S.A.8
Valeyre, D.9
Noble, P.W.10
-
79
-
-
84875167034
-
Pirfenidone: A novel agent for the treatment of idiopathic pulmonary fibrosis
-
Potts J, Yogaratnam D: Pirfenidone: a novel agent for the treatment of idiopathic pulmonary fibrosis. Ann Pharmacother 2013; 47: 361-367.
-
(2013)
Ann Pharmacother
, vol.47
, pp. 361-367
-
-
Potts, J.1
Yogaratnam, D.2
-
80
-
-
84901796978
-
Management of idiopathic pulmonary fibrosis: Selected case reports
-
Kreuter M, Kardos P, Hoffstein V: Management of idiopathic pulmonary fibrosis: selected case reports. Eur Respir Rev 2014; 23: 239-248.
-
(2014)
Eur Respir Rev
, vol.23
, pp. 239-248
-
-
Kreuter, M.1
Kardos, P.2
Hoffstein, V.3
-
81
-
-
84883054431
-
Safety and efficacy of pirfenidone in idiopathic pulmonary fibrosis in clinical practice
-
Okuda R, Hagiwara E, Baba T, Kitamura H, Kato T, Ogura T: Safety and efficacy of pirfenidone in idiopathic pulmonary fibrosis in clinical practice. Respir Med 2013; 107: 1431-1437.
-
(2013)
Respir Med
, vol.107
, pp. 1431-1437
-
-
Okuda, R.1
Hagiwara, E.2
Baba, T.3
Kitamura, H.4
Kato, T.5
Ogura, T.6
-
82
-
-
84901810710
-
Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis
-
Richeldi L, du Bois RM, Raghu G, Azuma A, et al: Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med 2014; 370: 2071-2082.
-
(2014)
N Engl J Med
, vol.370
, pp. 2071-2082
-
-
Richeldi, L.1
Du Bois, R.M.2
Raghu, G.3
Azuma, A.4
-
83
-
-
84876579887
-
Nintedanib (bibf 1120) for ipf: A tomorrow therapy?
-
Antoniu SA: Nintedanib (BIBF 1120) for IPF: a tomorrow therapy? Multidiscip Respir Med 2012; 7: 41.
-
(2012)
Multidiscip Respir Med
, vol.7
, pp. 41
-
-
Antoniu, S.A.1
-
84
-
-
84879286188
-
Reducing lung function decline in patients with idiopathic pulmonary fibrosis: Potential of nintedanib
-
Woodcock HV, Molyneaux PL, Maher TM: Reducing lung function decline in patients with idiopathic pulmonary fibrosis: potential of nintedanib. Drug Des Devel Ther 2013; 7: 503-510.
-
(2013)
Drug des Devel Ther
, vol.7
, pp. 503-510
-
-
Woodcock, H.V.1
Molyneaux, P.L.2
Maher, T.M.3
-
85
-
-
84898792564
-
Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis
-
Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B: Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J Pharmacol Exp Ther 2014; 349: 209-220.
-
(2014)
J Pharmacol Exp Ther
, vol.349
, pp. 209-220
-
-
Wollin, L.1
Maillet, I.2
Quesniaux, V.3
Holweg, A.4
Ryffel, B.5
-
86
-
-
78650053726
-
A ccl2-based fusokine as a novel biopharmaceutical for the treatment of ccr2-driven autoimmune diseases
-
Rafei M, Galipeau J: A CCL2-based fusokine as a novel biopharmaceutical for the treatment of CCR2-driven autoimmune diseases. Crit Rev Immunol 2010; 30: 449-461.
-
(2010)
Crit Rev Immunol
, vol.30
, pp. 449-461
-
-
Rafei, M.1
Galipeau, J.2
-
87
-
-
77955090022
-
The role of monocyte chemoattractant protein mcp1/ccl2 in neuroinflammatory diseases
-
Conductier G, Blondeau N, Guyon A, Nahon JL, Rovere C: The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases. J Neuroimmunol 2010; 224: 93-100.
-
(2010)
J Neuroimmunol
, vol.224
, pp. 93-100
-
-
Conductier, G.1
Blondeau, N.2
Guyon, A.3
Nahon, J.L.4
Rovere, C.5
-
88
-
-
0242273334
-
Monocyte chemoattractant protein-1 (ccl2) in inflammatory disease and adaptive immunity: Therapeutic opportunities and controversies
-
Daly C, Rollins BJ: Monocyte chemoattractant protein-1 (CCL2) in inflammatory disease and adaptive immunity: therapeutic opportunities and controversies. Microcirculation 2003; 10: 247-257.
-
(2003)
Microcirculation
, vol.10
, pp. 247-257
-
-
Daly, C.1
Rollins, B.J.2
-
89
-
-
0042355686
-
Polymorphism of monocyte chemoattractant protein 1 in crohn's disease
-
Herfarth H, Goke M, Hellerbrand C, Muhlbauer M, Vogl D, Scholmerich J, Rogler G: Polymorphism of monocyte chemoattractant protein 1 in Crohn's disease. Int J Colorectal Dis 2003; 18: 401-405.
-
(2003)
Int J Colorectal Dis
, vol.18
, pp. 401-405
-
-
Herfarth, H.1
Goke, M.2
Hellerbrand, C.3
Muhlbauer, M.4
Vogl, D.5
Scholmerich, J.6
Rogler, G.7
-
90
-
-
0036020947
-
Regulation of migration of human colonic myofibroblasts
-
Leeb SN, Vogl D, Falk W, Schölmerich J, Rogler G, Gelbmann CM: Regulation of migration of human colonic myofibroblasts. Growth Factors 2002; 20: 81-91.
-
(2002)
Growth Factors
, vol.20
, pp. 81-91
-
-
Leeb, S.N.1
Vogl, D.2
Falk, W.3
Schölmerich, J.4
Rogler, G.5
Gelbmann, C.M.6
-
91
-
-
33745151943
-
Monocyte chemoattractant protein-1 (mcp-1) inhibits the intestinal- like differentiation of monocytes
-
Spoettl T, Hausmann M, Herlyn M, Gunckel M, Dirmeier A, Falk W, Herfarth H, Schoelmerich J, Rogler G: Monocyte chemoattractant protein-1 (MCP-1) inhibits the intestinal- like differentiation of monocytes. Clin Exp Immunol 2006; 145: 190-199.
-
(2006)
Clin Exp Immunol
, vol.145
, pp. 190-199
-
-
Spoettl, T.1
Hausmann, M.2
Herlyn, M.3
Gunckel, M.4
Dirmeier, A.5
Falk, W.6
Herfarth, H.7
Schoelmerich, J.8
Rogler, G.9
-
92
-
-
34247586091
-
Induction of il-13 triggers tgfbeta1- dependent tissue fibrosis in chronic 2, 4,6-trinitrobenzene sulfonic acid colitis
-
Fichtner-Feigl S, Fuss IJ, Young CA, Watanabe T, Geissler EK, Schlitt HJ, Kitani A, Strober W: Induction of IL-13 triggers TGFbeta1- dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis. J Immunol 2007; 178: 5859-5870.
-
(2007)
J Immunol
, vol.178
, pp. 5859-5870
-
-
Fichtner-Feigl, S.1
Fuss, I.J.2
Young, C.A.3
Watanabe, T.4
Geissler, E.K.5
Schlitt, H.J.6
Kitani, A.7
Strober, W.8
-
93
-
-
57249094020
-
IL-13 signaling via il-13r alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic tnbs colitis
-
2013 e1-7
-
Fichtner-Feigl S, Young CA, Kitani A, Geissler EK, Schlitt HJ, Strober W: IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis. Gastroenterology 2008; 135: 2003-2013, 2013 e1-7.
-
(2008)
Gastroenterology
, vol.135
, pp. 2003-2013
-
-
Fichtner-Feigl, S.1
Young, C.A.2
Kitani, A.3
Geissler, E.K.4
Schlitt, H.J.5
Strober, W.6
-
94
-
-
4644225081
-
IL-13 activates a mechanism of tissue fibrosis that is completely tgf-beta independent
-
Kaviratne M, Hesse M, Leusink M, Cheever AW, Davies SJ, McKerrow JH, Wakefield LM, Letterio JJ, Wynn TA: IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent. J Immunol 2004; 173: 4020-4029.
-
(2004)
J Immunol
, vol.173
, pp. 4020-4029
-
-
Kaviratne, M.1
Hesse, M.2
Leusink, M.3
Cheever, A.W.4
Davies, S.J.5
McKerrow, J.H.6
Wakefield, L.M.7
Letterio, J.J.8
Wynn, T.A.9
-
95
-
-
84871153584
-
Interleukin-13 and transforming growth factor beta synergise in the pathogenesis of human intestinal fistulae
-
Scharl M, Frei S, Pesch T, Kellermeier S, Arikkat J, Frei P, Fried M, Weber A, Jehle E, Ruhl A, Rogler G: Interleukin-13 and transforming growth factor beta synergise in the pathogenesis of human intestinal fistulae. Gut 2013; 62: 63-72.
-
(2013)
Gut
, vol.62
, pp. 63-72
-
-
Scharl, M.1
Frei, S.2
Pesch, T.3
Kellermeier, S.4
Arikkat, J.5
Frei, P.6
Fried, M.7
Weber, A.8
Jehle, E.9
Ruhl, A.10
Rogler, G.11
-
96
-
-
84883413596
-
Pharmacological treatment of idiopathic pulmonary fibrosis: From the past to the future
-
Antoniou KM, Margaritopoulos GA, Siafakas NM: Pharmacological treatment of idiopathic pulmonary fibrosis: from the past to the future. Eur Respir Rev 2013; 22: 281-291.
-
(2013)
Eur Respir Rev
, vol.22
, pp. 281-291
-
-
Antoniou, K.M.1
Margaritopoulos, G.A.2
Siafakas, N.M.3
-
97
-
-
0345824715
-
Idiopathic pulmonary fibrosis study g: A placebo- controlled trial of interferon gamma- 1b in patients with idiopathic pulmonary fibrosis
-
Raghu G, Brown KK, Bradford WZ, Starko K, Noble PW, Schwartz DA, King TE Jr, Idiopathic Pulmonary Fibrosis Study G: A placebo- controlled trial of interferon gamma- 1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004; 350: 125-133.
-
(2004)
N Engl J Med
, vol.350
, pp. 125-133
-
-
Raghu, G.1
Brown, K.K.2
Bradford, W.Z.3
Starko, K.4
Noble, P.W.5
Schwartz, D.A.6
King, T.E.7
-
98
-
-
67650349068
-
Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (inspire): A multicentre, randomised, placebo-controlled trial
-
King TE Jr, Albera C, Bradford WZ, Costabel U, Hormel P, Lancaster L, Noble PW, Sahn SA, Szwarcberg J, Thomeer M, Valeyre D, du Bois RM, Group IS: Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet 2009; 374: 222-228.
-
(2009)
Lancet
, vol.374
, pp. 222-228
-
-
King, T.E.1
Albera, C.2
Bradford, W.Z.3
Costabel, U.4
Hormel, P.5
Lancaster, L.6
Noble, P.W.7
Sahn, S.A.8
Szwarcberg, J.9
Thomeer, M.10
Valeyre, D.11
Du Bois, R.M.12
-
99
-
-
28144459814
-
High-dose acetylcysteine in idiopathic pulmonary fibrosis
-
Demedts M, Behr J, Buhl R, et al: High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 2005; 353: 2229-2242.
-
(2005)
N Engl J Med
, vol.353
, pp. 2229-2242
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
-
100
-
-
84861394764
-
Prednisone, azathioprine, and n-acetylcysteine for pulmonary fibrosis
-
Idiopathic Pulmonary Fibrosis Clinical Research Network, Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ: Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis. N Engl J Med 2012; 366: 1968-1977.
-
(2012)
N Engl J Med
, vol.366
, pp. 1968-1977
-
-
Idiopathic Pulmonary Fibrosis Clinical Research Network1
Raghu, G.2
Anstrom, K.J.3
King, T.E.4
Lasky, J.A.5
Martinez, F.J.6
-
101
-
-
77951160564
-
Pirfenidone in idiopathic pulmonary fibrosis
-
Taniguchi H, Ebina M, Kondoh Y, et al: Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 2010; 35: 821-829.
-
(2010)
Eur Respir J
, vol.35
, pp. 821-829
-
-
Taniguchi, H.1
Ebina, M.2
Kondoh, Y.3
-
102
-
-
79956341531
-
Pirfenidone in patients with idiopathic pulmonary fibrosis (capacity): Two randomised trials
-
Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE Jr, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM, Group CS: Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 2011; 377: 1760-1769.
-
(2011)
Lancet
, vol.377
, pp. 1760-1769
-
-
Noble, P.W.1
Albera, C.2
Bradford, W.Z.3
Costabel, U.4
Glassberg, M.K.5
Kardatzke, D.6
King, T.E.7
Lancaster, L.8
Sahn, S.A.9
Szwarcberg, J.10
Valeyre, D.11
Du Bois, R.M.12
-
103
-
-
84863450246
-
A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis
-
Noth I, Anstrom KJ, Calvert SB, de Andrade J, Flaherty KR, Glazer C, Kaner RJ, Olman MA, Idiopathic Pulmonary Fibrosis Clinical Research Network: A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2012; 186: 88-95.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 88-95
-
-
Idiopathic Pulmonary Fibrosis Clinical Research Network1
Noth, I.2
Anstrom, K.J.3
Calvert, S.B.4
De Andrade, J.5
Flaherty, K.R.6
Glazer, C.7
Kaner, R.J.8
Olman, M.A.9
-
104
-
-
80053091084
-
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis
-
Richeldi L, Costabel U, Selman M, et al: Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med 2011; 365: 1079-1087.
-
(2011)
N Engl J Med
, vol.365
, pp. 1079-1087
-
-
Richeldi, L.1
Costabel, U.2
Selman, M.3
-
105
-
-
77749324295
-
Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo- controlled trial results
-
Daniels CE, Lasky JA, Limper AH, Mieras K, Gabor E, Schroeder DR, Imatinib-IPF Study Investigators: Imatinib treatment for idiopathic pulmonary fibrosis: randomized placebo- controlled trial results. Am J Respir Crit Care Med 2010; 181: 604-610.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 604-610
-
-
Daniels, C.E.1
Lasky, J.A.2
Limper, A.H.3
Mieras, K.4
Gabor, E.5
Schroeder, D.R.6
-
106
-
-
77956640423
-
A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis
-
Idiopathic Pulmonary Fibrosis Clinical Research Network, Zisman DA, Schwarz M, Anstrom KJ, Collard HR, Flaherty KR, Hunninghake GW: A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. N Engl J Med 2010; 363: 620-628.
-
(2010)
N Engl J Med
, vol.363
, pp. 620-628
-
-
Idiopathic Pulmonary Fibrosis Clinical Research Network1
Zisman, D.A.2
Schwarz, M.3
Anstrom, K.J.4
Collard, H.R.5
Flaherty, K.R.6
Hunninghake, G.W.7
-
107
-
-
37849012578
-
Build-1: A randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Behr J, Brown KK, du Bois RM, Lancaster L, de Andrade JA, Stahler G, Leconte I, Roux S, Raghu G: Build-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 177: 75-81.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 75-81
-
-
King, T.E.1
Behr, J.2
Brown, K.K.3
Du Bois, R.M.4
Lancaster, L.5
De Andrade, J.A.6
Stahler, G.7
Leconte, I.8
Roux, S.9
Raghu, G.10
-
108
-
-
80051566676
-
BUILD-3: A randomized controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Brown KK, Raghu G, du Bois RM, Lynch DA, Martinez F, Valeyre D, Leconte I, Morganti A, Roux S, Behr J: BUILD-3: A randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011; 184: 92-99.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 92-99
-
-
King, T.E.1
Brown, K.K.2
Raghu, G.3
Du Bois, R.M.4
Lynch, D.A.5
Martinez, F.6
Valeyre, D.7
Leconte, I.8
Morganti, A.9
Roux, S.10
Behr, J.11
-
109
-
-
84877297353
-
Treatment of idiopathic pulmonary fibrosis with ambrisentan: A parallel, randomized trial
-
Raghu G, Behr J, Brown KK, et al: Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. Ann Intern Med 2013; 158: 641-649.
-
(2013)
Ann Intern Med
, vol.158
, pp. 641-649
-
-
Raghu, G.1
Behr, J.2
Brown, K.K.3
-
110
-
-
84865136582
-
Efficacy and safety of macitentan in idiopathic pulmonary fibrosis: Results of a prospective, randomized, double-blind, placebo- controlled trial
-
Raghu G, Million-Rousseau R, Morganti A, et al: Efficacy and safety of macitentan in idiopathic pulmonary fibrosis: results of a prospective, randomized, double-blind, placebo- controlled trial. Clin Trials Idiopath Pulmonary Fibrosis Sarcoidosis 2012, p A3631.
-
(2012)
Clin Trials Idiopath Pulmonary Fibrosis Sarcoidosis
, pp. A3631
-
-
Raghu, G.1
Million-Rousseau, R.2
Morganti, A.3
|