A relevant experimental model for human bronchiolitis obliterans syndrome

Journal of Heart and Lung Transplantation

Volumn 32, Issue 11, 2013, Pages 1131-1139

  Atanasova, Srebrena ^a   Hirschburger, Markus ^a   Jonigk, Danny ^b   Obert, Martin ^a   Petri, Kathrin ^a   Evers, Alena ^a   Hecker, Andreas ^a   Schmitz, Jessica ^a   Kaufmann, Andreas ^c   Wilhelm, Jochen ^a   Chakraborty, Trinad ^a   Warnecke, Gregor ^d   Gottlieb, Jens ^a   Padberg, Winfried ^a   Grau, Veronika ^a,b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d German Center for Lung Research (DZL)   (Germany)

Author keywords

chemokines; chronic allograft damage; cytokines; lipopolysaccharide; lung transplantation; pulmonary vascular remodeling

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; CYCLOSPORIN A; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LIPOPOLYSACCHARIDE; RANTES; TOLL LIKE RECEPTOR 2;

ADVENTITIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; ATELECTASIS; BRONCHIOLITIS OBLITERANS; CELL INFILTRATION; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE OVEREXPRESSION; GRAFT DYSFUNCTION; GRAFT RECIPIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; ISOGRAFT; LEWIS RAT; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MONONUCLEAR CELL; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; RETRANSPLANTATION; VASCULITIS;

CHEMOKINES; CHRONIC ALLOGRAFT DAMAGE; CYTOKINES; LIPOPOLYSACCHARIDE; LUNG TRANSPLANTATION; PULMONARY VASCULAR REMODELING;

ANIMALS; BRONCHIOLITIS OBLITERANS; CHEMOKINES; DISEASE MODELS, ANIMAL; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSION; LIPOPOLYSACCHARIDES; LUNG; LUNG TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; RATS; RATS, INBRED F344; RATS, INBRED LEW; RISK FACTORS; SYNDROME; TOLL-LIKE RECEPTORS;

EID: 84885955925     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2013.07.016     Document Type: Article

References (30)

1. J.D. Christie, L.B. Edwards, and A.Y. Kucheryavaya International Society of Heart and Lung Transplantation. The registry of the International Society for Heart and Lung Transplantation: 29th adult lung and heart-lung transplant report-2012 J Heart Lung Transplant 31 2012 1073 1086
2. M. Estenne, J.R. Maurer, and A. Boehler Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria J Heart Lung Transplant 21 2002 297 310
3. T. Martinu, D.N. Howell, R.D. Davis, M.P. Steele, and S.M. Palmer Pathologic correlates of bronchiolitis obliterans syndrome in pulmonary retransplant recipients Chest 129 2006 1016 1023
4. S.A. Yousem, I.L. Paradis, and J.H. Dauber Pulmonary arteriosclerosis in long-term human heart-lung transplant recipients Transplantation 47 1989 564 569
5. S. Stewart, M.C. Fishbein, and G.I. Snell Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection J Heart Lung Transplant 26 2007 1229 1242
6. J. Gottlieb, J. Szangolies, T. Koehnlein, H. Golpon, A. Simon, and T. Welte Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation Transplantation 85 2008 36 41
7. H. Reichenspurner, V. Soni, M. Nitschke, G.J. Berry, T.R. Brazelton, and R. Shorthouse Obliterative airway disease after heterotopic tracheal xenotransplantation: pathogenesis and prevention using new immunosuppressive agents Transplantation 64 1997 373 383
8. I. Schade, S. Roth-Eichhorn, and M. Kasper Benefit of phosphodiesterase 4 inhibitors as supplemental therapy after lung transplantation concerning their antiproliferative effects: an experimental study using a heterotopic rodent model Transplantation 74 2002 326 334
9. A.N. Babu, T. Murakawa, and J.M. Thurman Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis J Clin Invest 117 2007 3774 3785
10. A.E. Dutly, C.F. Andrade, and R. Verkaik A novel model for post-transplant obliterative airway disease reveals angiogenesis from the pulmonary circulation Am J Transplant 5 2005 248 254
11. Y. Matsumura, A. Marchevsky, X.J. Zuo, R.M. Kass, J.M. Matloff, and S.C. Jordan Assessment of pathological changes associated with chronic allograft rejection and tolerance in two experimental models of rat lung transplantation Transplantation 59 1995 1509 1517
12. N. Zweers, A.H. Petersen, and J.A. van der Hoeven Donor brain death aggravates chronic rejection after lung transplantation in rats Transplantation 78 2004 1251 1258
13. M. Hirschburger, S. Greschus, and T. Kuchenbuch Lung transplantation in the Fischer 344 - >Wistar Kyoto rat strain combination is not suitable to study bronchiolitis obliterans J Heart Lung Transplant 26 2007 390 398
14. T. Uyama, J.B. Winter, G. Groen, C.R. Wildevuur, Y. Monden, and J. Prop Late airway changes caused by chronic rejection in rat lung allografts Transplantation 54 1992 809 812
15. A.G. Lee, F.M. Wagner, M.F. Chen, C. Serrick, A. Giaid, and H. Shennib A novel charcoal-induced model of obliterative bronchiolitis-like lesions: implications of chronic nonspecific airway inflammation in the development of posttransplantation obliterative bronchiolitis J Thorac Cardiovasc Surg 115 1998 822 827
16. M. Okazaki, A.S. Krupnick, and C.G. Kornfeld A mouse model of orthotopic vascularized aerated lung transplantation Am J Transplant 7 2007 1672 1679
17. L. Fan, H.L. Benson, and R. Vittal Neutralizing IL-17 prevents obliterative bronchiolitis in murine orthotopic lung transplantation Am J Transplant 11 2011 911 922
18. S. De Vleeschauwer, W. Jungraithmayr, and S. Wauters Chronic rejection pathology after orthotopic lung transplantation in mice: the development of a murine BOS model and its drawbacks PLoS One 7 2012 e29802
19. M. Sato, and S. Keshavjee Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling Semin Thorac Cardiovasc Surg 20 2008 173 182
20. V.G. Valentine, M.R. Gupta, and J.E. Walker Jr Effect of etiology and timing of respiratory tract infections on development of bronchiolitis obliterans syndrome J Heart Lung Transplant 28 2009 163 169
21. K. Yagyu, and P.J. van Breda Vriesman Apoptosis in bronchiolitis obliterans, chronic rejection and infection after lung transplantation in rats Transplant Proc 29 1997 1532 1535
22. J.B. Winter, A.S. Gouw, M. Groen, C. Wildevuur, and J. Prop Respiratory viral infections aggravate airway damage caused by chronic rejection in rat lung allografts Transplantation 57 1994 418 422
23. S. Blöcher, S. Wilker, and J. Sucke Acute rejection of experimental lung allografts: characterization of intravascular mononuclear leukocytes Clin Immunol 124 2007 98 108
24. S. Greschus, T. Kuchenbuch, and C. Plötz Monitoring of experimental rat lung transplants by high resolution flat-panel volumetric computer tomography (fpVCT) J Invest Surg 22 2009 69 75
25. M. Reynaud-Gaubert, V. Marin, and X. Thirion Upregulation of chemokines in bronchoalveolar lavage fluid as a predictive marker of post-transplant airway obliteration J Heart Lung Transplant 21 2002 721 730
26. D.C. Neujahr, S.D. Perez, and A. Mohammed Cumulative exposure to gamma interferon-dependent chemokines CXCL9 and CXCL10 correlates with worse outcome after lung transplant Am J Transplant 12 2012 438 446
27. S.A. Yousem, G.J. Berry, and E.M. Brunt A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: lung rejection study group J Heart Lung Transplant 9 1990 593 601
28. R. Saggar, D.J. Ross, and R. Saggar Pulmonary hypertension associated with lung transplantation obliterative bronchiolitis and vascular remodeling of the allograft Am J Transplant 8 2008 1921 1930
29. S.D. Nathan, O.A. Shlobin, and S. Ahmad Pulmonary hypertension in patients with bronchiolitis obliterans syndrome listed for retransplantation Am J Transplant 8 2008 1506 1511
30. S. Garantziotis, S.M. Palmer, and L.D. Snyder Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide Transplantation 84 2007 1012 1019