-
1
-
-
84919735382
-
-
Global Tuberculosis report
-
Global Tuberculosis report. In [http://www.who.int/iris/bitstream/10665/91355/1/9789241564656_eng.pdf]
-
-
-
-
2
-
-
84877267006
-
Advances in the development of new tuberculosis drugs and treatment regimens
-
COI: 1:CAS:528:DC%2BC3sXms1Kmsrk%3D
-
Zumla A, Nahid P, Cole ST: Advances in the development of new tuberculosis drugs and treatment regimens.Nat Rev Drug Discov 2013, 12:388–404.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 388-404
-
-
Zumla, A.1
Nahid, P.2
Cole, S.T.3
-
3
-
-
77952542701
-
Multidrug-resistant and extensively drug-resistant tuberculosis: A threat to global control of tuberculosis
-
Gandhi NR, Nunn P, Dheda K, Schaaf HS, Zignol M, van Soolingen D, Jensen P, Bayona J: Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis.Lancet 2010, 375:1830–1843.
-
(2010)
Lancet
, vol.375
, pp. 1830-1843
-
-
Gandhi, N.R.1
Nunn, P.2
Dheda, K.3
Schaaf, H.S.4
Zignol, M.5
van Soolingen, D.6
Jensen, P.7
Bayona, J.8
-
4
-
-
84872131305
-
Infectious disease. Approval of novel TB drug celebrated--with restraint
-
COI: 1:CAS:528:DC%2BC3sXhtFCjt78%3D
-
Cohen J: Infectious disease. Approval of novel TB drug celebrated--with restraint.Science 2013, 339:130.
-
(2013)
Science
, vol.339
, pp. 130
-
-
Cohen, J.1
-
5
-
-
84874974106
-
21st century natural product research and drug development and traditional medicines
-
COI: 1:CAS:528:DC%2BC3sXjvFWnsLk%3D
-
Ngo LT, Okogun JI, Folk WR: 21st century natural product research and drug development and traditional medicines.Nat Prod Rep 2013, 30:584–592.
-
(2013)
Nat Prod Rep
, vol.30
, pp. 584-592
-
-
Ngo, L.T.1
Okogun, J.I.2
Folk, W.R.3
-
6
-
-
68449086364
-
New anti-tuberculosis drugs: Strategies, sources and new molecules
-
COI: 1:CAS:528:DC%2BD1MXnt1Ggsr8%3D
-
Palomino JC, Ramos DF, da Silva PA: New anti-tuberculosis drugs: strategies, sources and new molecules.Curr Med Chem 2009, 16:1898–1904.
-
(2009)
Curr Med Chem
, vol.16
, pp. 1898-1904
-
-
Palomino, J.C.1
Ramos, D.F.2
da Silva, P.A.3
-
7
-
-
33644535147
-
Natural products–the future scaffolds for novel antibiotics?
-
COI: 1:CAS:528:DC%2BD28XitVKjurY%3D
-
Butler MS, Buss AD: Natural products–the future scaffolds for novel antibiotics?Biochem Pharmacol 2006, 71:919–929.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 919-929
-
-
Butler, M.S.1
Buss, A.D.2
-
8
-
-
34249700741
-
Challenges and opportunities in drug discovery from plants
-
COI: 1:CAS:528:DC%2BD2sXmslOjsbY%3D
-
Jachak SM, Saklani A: Challenges and opportunities in drug discovery from plants.Curr Sci 2007, 92:1251–1257.
-
(2007)
Curr Sci
, vol.92
, pp. 1251-1257
-
-
Jachak, S.M.1
Saklani, A.2
-
9
-
-
84903516350
-
The success of natural products in drug discovery
-
Lahlou M: The success of natural products in drug discovery.Pharmacol Pharmacy 2013, 4:17–31.
-
(2013)
Pharmacol Pharmacy
, vol.4
, pp. 17-31
-
-
Lahlou, M.1
-
10
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
COI: 1:CAS:528:DC%2BC38XitVeku78%3D
-
Newman DJ, Cragg GM: Natural products as sources of new drugs over the 30 years from 1981 to 2010.J Nat Prod 2012, 75:311–335.
-
(2012)
J Nat Prod
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
11
-
-
84857231344
-
Recent advances in antitubercular natural products
-
COI: 1:CAS:528:DC%2BC38XisFOku7g%3D
-
Garcia A, Bocanegra-Garcia V, Palma-Nicolas JP, Rivera G: Recent advances in antitubercular natural products.Eur J Med Chem 2012, 49:1–23.
-
(2012)
Eur J Med Chem
, vol.49
, pp. 1-23
-
-
Garcia, A.1
Bocanegra-Garcia, V.2
Palma-Nicolas, J.P.3
Rivera, G.4
-
12
-
-
84867092241
-
Anti-tubercular activity of natural products: Recent developments
-
Tiwari VK, (ed), Research Signpost, Trivandrum, Kerala, India:
-
Rogoza LN: Anti-tubercular activity of natural products: Recent developments. In Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry. Edited by Tiwari VK. Trivandrum, Kerala, India: Research Signpost; 2011:103–120.
-
(2011)
Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry
, pp. 103-120
-
-
Rogoza, L.N.1
-
13
-
-
79952466815
-
Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery
-
COI: 1:CAS:528:DC%2BC3MXhsFyrtrc%3D
-
Ekins S, Freundlich JS, Choi I, Sarker M, Talcott C: Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery.Trends Microbiol 2011, 19:65–74.
-
(2011)
Trends Microbiol
, vol.19
, pp. 65-74
-
-
Ekins, S.1
Freundlich, J.S.2
Choi, I.3
Sarker, M.4
Talcott, C.5
-
14
-
-
84919735381
-
-
Open Source Drug Discovery Resources. In [http://www.osdd.net/research-development/publications-and-presentations]
-
-
-
-
15
-
-
84876736739
-
Use of natural products as chemical library for drug discovery and network pharmacology
-
COI: 1:CAS:528:DC%2BC3sXntlClsrc%3D
-
Gu J, Gui Y, Chen L, Yuan G, Lu HZ, Xu X: Use of natural products as chemical library for drug discovery and network pharmacology.PLoS One 2013, 8:e62839.
-
(2013)
PLoS One
, vol.8
, pp. e62839
-
-
Gu, J.1
Gui, Y.2
Chen, L.3
Yuan, G.4
Lu, H.Z.5
Xu, X.6
-
16
-
-
84875470601
-
Development of a natural products database from the biodiversity of Brazil
-
COI: 1:CAS:528:DC%2BC3sXhtFCnsr8%3D
-
Valli M, dos Santos RN, Figueira LD, Nakajima CH, Castro-Gamboa I, Andricopulo AD, Bolzani VS: Development of a natural products database from the biodiversity of Brazil.J Nat Prod 2013, 76:439–444.
-
(2013)
J Nat Prod
, vol.76
, pp. 439-444
-
-
Valli, M.1
dos Santos, R.N.2
Figueira, L.D.3
Nakajima, C.H.4
Castro-Gamboa, I.5
Andricopulo, A.D.6
Bolzani, V.S.7
-
17
-
-
84876082619
-
CamMedNP: Building the Cameroonian 3D structural natural products database for virtual screening
-
Ntie-Kang F, Mbah JA, Mbaze LM, Lifongo LL, Scharfe M, Hanna JN, Cho-Ngwa F, Onguene PA, Owono Owono LC, Megnassan E, Sippl W, Efange SM: CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening.BMC Complement Altern Med 2013, 13:88.
-
(2013)
BMC Complement Altern Med
, vol.13
, pp. 88
-
-
Ntie-Kang, F.1
Mbah, J.A.2
Mbaze, L.M.3
Lifongo, L.L.4
Scharfe, M.5
Hanna, J.N.6
Cho-Ngwa, F.7
Onguene, P.A.8
Owono Owono, L.C.9
Megnassan, E.10
Sippl, W.11
Efange, S.M.12
-
18
-
-
33644878571
-
SuperNatural: A searchable database of available natural compounds
-
COI: 1:CAS:528:DC%2BD28XisFyntw%3D%3D
-
Dunkel M, Fullbeck M, Neumann S, Preissner R: SuperNatural: a searchable database of available natural compounds.Nucleic Acids Res 2006, 34:D678–D683.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. D678-D683
-
-
Dunkel, M.1
Fullbeck, M.2
Neumann, S.3
Preissner, R.4
-
19
-
-
78651326779
-
HIT: Linking herbal active ingredients to targets
-
COI: 1:CAS:528:DC%2BC3sXivF2ltLo%3D
-
Ye H, Ye L, Kang H, Zhang D, Tao L, Tang K, Liu X, Zhu R, Liu Q, Chen YZ, Li Y, Cao Z: HIT: linking herbal active ingredients to targets.Nucleic Acids Res 2011, 39:D1055–D1059.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. D1055-D1059
-
-
Ye, H.1
Ye, L.2
Kang, H.3
Zhang, D.4
Tao, L.5
Tang, K.6
Liu, X.7
Zhu, R.8
Liu, Q.9
Chen, Y.Z.10
Li, Y.11
Cao, Z.12
-
20
-
-
84876560772
-
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database
-
COI: 1:CAS:528:DC%2BC38XhvV2ksbnK
-
Mangal M, Sagar P, Singh H, Raghava GP, Agarwal SM: NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database.Nucleic Acids Res 2013, 41:D1124–D1129.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D1124-D1129
-
-
Mangal, M.1
Sagar, P.2
Singh, H.3
Raghava, G.P.4
Agarwal, S.M.5
-
21
-
-
79251561193
-
TCM Database@Taiwan: The world’s largest traditional Chinese medicine database for drug screening in silico
-
COI: 1:CAS:528:DC%2BC3MXosVynug%3D%3D
-
Chen CY: TCM Database@Taiwan: the world’s largest traditional Chinese medicine database for drug screening in silico.PLoS One 2011, 6:e15939.
-
(2011)
PLoS One
, vol.6
, pp. e15939
-
-
Chen, C.Y.1
-
22
-
-
84874889837
-
TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis
-
COI: 1:CAS:528:DC%2BC38XhvV2ktrfM
-
Xue R, Fang Z, Zhang M, Yi Z, Wen C, Shi T: TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis.Nucleic Acids Res 2013, 41:D1089–D1095.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D1089-D1095
-
-
Xue, R.1
Fang, Z.2
Zhang, M.3
Yi, Z.4
Wen, C.5
Shi, T.6
-
23
-
-
84879981381
-
HIM-herbal ingredients in-vivo metabolism database
-
COI: 1:CAS:528:DC%2BC3sXhtVCmsLfI
-
Kang H, Tang K, Liu Q, Sun Y, Huang Q, Zhu R, Gao J, Zhang D, Huang C, Cao Z: HIM-herbal ingredients in-vivo metabolism database.J Cheminform 2013, 5:28.
-
(2013)
J Cheminform
, vol.5
, pp. 28
-
-
Kang, H.1
Tang, K.2
Liu, Q.3
Sun, Y.4
Huang, Q.5
Zhu, R.6
Gao, J.7
Zhang, D.8
Huang, C.9
Cao, Z.10
-
24
-
-
84891425051
-
AfroDb: A select highly potent and diverse natural product library from African Medicinal Plants
-
COI: 1:CAS:528:DC%2BC3sXhslClur3I
-
Ntie-Kang F, Zofou D, Babiaka SB, Meudom R, Scharfe M, Lifongo LL, Mbah JA, Mbaze LM, Sippl W, Efange SM: AfroDb: A select highly potent and diverse natural product library from African Medicinal Plants.PLoS One 2013, 8:e78085.
-
(2013)
PLoS One
, vol.8
, pp. e78085
-
-
Ntie-Kang, F.1
Zofou, D.2
Babiaka, S.B.3
Meudom, R.4
Scharfe, M.5
Lifongo, L.L.6
Mbah, J.A.7
Mbaze, L.M.8
Sippl, W.9
Efange, S.M.10
-
25
-
-
84888633514
-
ConMedNP: A natural product library from Central African medicinal plants for drug discovery
-
COI: 1:CAS:528:DC%2BC3sXhvVeisrfO
-
Ntie-Kang F, Onguene PA, Scharfe M, Owono Owono LC, Megnassan E, Mbaze LM, Sippl W, Efange SMN: ConMedNP: a natural product library from Central African medicinal plants for drug discovery.RSC Adv 2014, 4:409–419.
-
(2014)
RSC Adv
, vol.4
, pp. 409-419
-
-
Ntie-Kang, F.1
Onguene, P.A.2
Scharfe, M.3
Owono Owono, L.C.4
Megnassan, E.5
Mbaze, L.M.6
Sippl, W.7
Efange, S.M.N.8
-
26
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
COI: 1:CAS:528:DC%2BD3MXitVOhs7o%3D
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ: Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.Adv Drug Deliv Rev 2001, 46:3–26.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
27
-
-
0001611357
-
JChem: Java applets and modules supporting chemical database handling from web browsers
-
COI: 1:CAS:528:DC%2BD3cXlsl2mug%3D%3D
-
Csizmadia F: JChem: Java applets and modules supporting chemical database handling from web browsers.J Chem Inf Comput Sci 2000, 40:323–324.
-
(2000)
J Chem Inf Comput Sci
, vol.40
, pp. 323-324
-
-
Csizmadia, F.1
-
28
-
-
18344379900
-
PowerMV: A software environment for molecular viewing, descriptor generation, data analysis and hit evaluation
-
COI: 1:CAS:528:DC%2BD2MXntFyqsQ%3D%3D
-
Liu K, Feng J, Young SS: PowerMV: a software environment for molecular viewing, descriptor generation, data analysis and hit evaluation.J Chem Inf Model 2005, 45:515–522.
-
(2005)
J Chem Inf Model
, vol.45
, pp. 515-522
-
-
Liu, K.1
Feng, J.2
Young, S.S.3
-
29
-
-
69649109364
-
Circos: An information aesthetic for comparative genomics
-
COI: 1:CAS:528:DC%2BD1MXhtFCjsLvJ
-
Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, Jones SJ, Marra MA: Circos: an information aesthetic for comparative genomics.Genome Res 2009, 19:1639–1645.
-
(2009)
Genome Res
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.1
Schein, J.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
Jones, S.J.7
Marra, M.A.8
-
30
-
-
0037030653
-
Molecular properties that influence the oral bioavailability of drug candidates
-
COI: 1:CAS:528:DC%2BD38XjsFCmt7g%3D
-
Veber DF, Johnson SR, Cheng HY, Smith BR, Ward KW, Kopple KD: Molecular properties that influence the oral bioavailability of drug candidates.J Med Chem 2002, 45:2615–2623.
-
(2002)
J Med Chem
, vol.45
, pp. 2615-2623
-
-
Veber, D.F.1
Johnson, S.R.2
Cheng, H.Y.3
Smith, B.R.4
Ward, K.W.5
Kopple, K.D.6
-
31
-
-
0141726877
-
A ‘rule of three’ for fragment-based lead discovery?
-
Congreve M, Carr R, Murray C, Jhoti H: A ‘rule of three’ for fragment-based lead discovery?Drug Discov Today 2003, 8:876–877.
-
(2003)
Drug Discov Today
, vol.8
, pp. 876-877
-
-
Congreve, M.1
Carr, R.2
Murray, C.3
Jhoti, H.4
-
32
-
-
84919763952
-
Nutraceuticals: A boom to medical industry
-
Kumar R, Singh G, Swami G, Krishan P, Kumari P, Rizvi SI: Nutraceuticals: a boom to medical industry.Res Gate: Pharmaceut Sci 2013, 2:8.
-
(2013)
Res Gate: Pharmaceut Sci
, vol.2
, pp. 8
-
-
Kumar, R.1
Singh, G.2
Swami, G.3
Krishan, P.4
Kumari, P.5
Rizvi, S.I.6
-
33
-
-
0034073605
-
Property distribution of drug-related chemical databases
-
COI: 1:CAS:528:DC%2BD3cXitlCktrk%3D
-
Oprea TI: Property distribution of drug-related chemical databases.J Comput Aided Mol Des 2000, 14:251–264.
-
(2000)
J Comput Aided Mol Des
, vol.14
, pp. 251-264
-
-
Oprea, T.I.1
-
34
-
-
0032600640
-
A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases
-
COI: 1:CAS:528:DyaK1cXnvFGrurk%3D
-
Ghose AK, Viswanadhan VN, Wendoloski JJ: A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases.J Comb Chem 1999, 1:55–68.
-
(1999)
J Comb Chem
, vol.1
, pp. 55-68
-
-
Ghose, A.K.1
Viswanadhan, V.N.2
Wendoloski, J.J.3
-
35
-
-
84856201851
-
Quantifying the chemical beauty of drugs
-
COI: 1:CAS:528:DC%2BC38Xht1aktLk%3D
-
Bickerton GR, Paolini GV, Besnard J, Muresan S, Hopkins AL: Quantifying the chemical beauty of drugs.Nat Chem 2012, 4:90–98.
-
(2012)
Nat Chem
, vol.4
, pp. 90-98
-
-
Bickerton, G.R.1
Paolini, G.V.2
Besnard, J.3
Muresan, S.4
Hopkins, A.L.5
-
36
-
-
0037439447
-
Nonleadlikeness and leadlikeness in biochemical screening
-
COI: 1:CAS:528:DC%2BD3sXmt1ansQ%3D%3D
-
Rishton GM: Nonleadlikeness and leadlikeness in biochemical screening.Drug Discov Today 2003, 8:86–96.
-
(2003)
Drug Discov Today
, vol.8
, pp. 86-96
-
-
Rishton, G.M.1
-
37
-
-
84873811860
-
Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis
-
COI: 1:CAS:528:DC%2BC3sXls1Omug%3D%3D
-
Ballell L, Bates RH, Young RJ, Alvarez-Gomez D, Alvarez-Ruiz E, Barroso V, Blanco D, Crespo B, Escribano J, Gonzalez R, Lozano S, Huss S, Santos-Villarejo A, Martín-Plaza JJ, Mendoza A, Rebollo-Lopez MJ, Remuiñan-Blanco M, Lavandera JL, Pérez-Herran E, Gamo-Benito FJ, García-Bustos JF, Barros D, Castro JP, Cammack N: Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.Chem Med Chem 2013, 8:313–321.
-
(2013)
Chem Med Chem
, vol.8
, pp. 313-321
-
-
Ballell, L.1
Bates, R.H.2
Young, R.J.3
Alvarez-Gomez, D.4
Alvarez-Ruiz, E.5
Barroso, V.6
Blanco, D.7
Crespo, B.8
Escribano, J.9
Gonzalez, R.10
Lozano, S.11
Huss, S.12
Santos-Villarejo, A.13
Martín-Plaza, J.J.14
Mendoza, A.15
Rebollo-Lopez, M.J.16
Remuiñan-Blanco, M.17
Lavandera, J.L.18
Pérez-Herran, E.19
Gamo-Benito, F.J.20
García-Bustos, J.F.21
Barros, D.22
Castro, J.P.23
Cammack, N.24
more..
-
38
-
-
84887302442
-
Target prediction for an open access set of compounds active against Mycobacterium tuberculosis
-
Martinez-Jimenez F, Papadatos G, Yang L, Wallace IM, Kumar V, Pieper U, Sali A, Brown JR, Overington JP, Marti-Renom MA: Target prediction for an open access set of compounds active against Mycobacterium tuberculosis.PLoS Comput Biol 2013, 9:e1003253.
-
(2013)
PLoS Comput Biol
, vol.9
, pp. e1003253
-
-
Martinez-Jimenez, F.1
Papadatos, G.2
Yang, L.3
Wallace, I.M.4
Kumar, V.5
Pieper, U.6
Sali, A.7
Brown, J.R.8
Overington, J.P.9
Marti-Renom, M.A.10
-
39
-
-
84906551223
-
New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 20
-
Clark A, Sarker M, Ekins S: New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 20.J Chem Informatics 2014, 6:38.
-
(2014)
J Chem Informatics
, vol.6
, pp. 38
-
-
Clark, A.1
Sarker, M.2
Ekins, S.3
|