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Volumn 145, Issue 1, 2015, Pages 25-31

Glutamine enhances tight junction protein expression and modulates corticotropin-releasing factor signaling in the jejunum of piglets

Author keywords

Corticotropin releasing factor; Glutamine; Pigs; Small intestine; Tight junction; Weaning stress

Indexed keywords

CLAUDIN 1; CLAUDIN 3; CLAUDIN 4; CORTICOTROPIN RELEASING FACTOR; GLUTAMINE; LACTULOSE; MANNITOL; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1; PROTEIN ZO2; PROTEIN ZO3; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG; ZONULA OCCLUDENS PROTEIN; CLAUDIN;

EID: 84919777118     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.202515     Document Type: Article
Times cited : (138)

References (59)
  • 1
    • 33749186777 scopus 로고    scopus 로고
    • Alterations in intestinal permeability
    • Arrieta MC, Bistritz L, Meddings JB. Alterations in intestinal permeability. Gut 2006;55:1512-20.
    • (2006) Gut , vol.55 , pp. 1512-1520
    • Arrieta, M.C.1    Bistritz, L.2    Meddings, J.B.3
  • 3
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009;9:799-809.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 5
    • 84882797836 scopus 로고    scopus 로고
    • Intestinal permeability defects: is it time to treat?
    • Odenwald MA, Turner JR. Intestinal permeability defects: is it time to treat? Clin Gastroenterol Hepatol 2013;11:1075-83.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 1075-1083
    • Odenwald, M.A.1    Turner, J.R.2
  • 6
    • 79955665201 scopus 로고    scopus 로고
    • Intestinal barrier function and absorption in pigs after weaning: a review
    • Wijtten PJ, van derMeulen J, VerstegenMW. Intestinal barrier function and absorption in pigs after weaning: a review. Br J Nutr 2011;105:967-81.
    • (2011) Br J Nutr , vol.105 , pp. 967-981
    • Wijtten, P.J.1    van derMeulen, J.2    Verstegen, M.W.3
  • 7
    • 0036786886 scopus 로고    scopus 로고
    • Effect of stress on the paracellular barrier in the rat ileum
    • Mazzon E, Sturniolo GC, Puzzolo D, Frisina N, Fries W. Effect of stress on the paracellular barrier in the rat ileum. Gut 2002;51:507-13.
    • (2002) Gut , vol.51 , pp. 507-513
    • Mazzon, E.1    Sturniolo, G.C.2    Puzzolo, D.3    Frisina, N.4    Fries, W.5
  • 8
    • 65549129528 scopus 로고    scopus 로고
    • Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects
    • Lambert GP. Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects. J Anim Sci 2009;87:E101-8.
    • (2009) J Anim Sci , vol.87 , pp. E101-E108
    • Lambert, G.P.1
  • 12
    • 0037369552 scopus 로고    scopus 로고
    • Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation
    • Berkes J, Viswanathan VK, Savkovic SD, Hecht G. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut 2003;52:439-51.
    • (2003) Gut , vol.52 , pp. 439-451
    • Berkes, J.1    Viswanathan, V.K.2    Savkovic, S.D.3    Hecht, G.4
  • 14
    • 77957228582 scopus 로고    scopus 로고
    • Increasing weaning age of piglets from 4 to 7 weeks reduces stress, increases post-weaning feed intake but does not improve intestinal functionality
    • van der Meulen J, Koopmans SJ, Dekker RA, Hoogendoorn A. Increasing weaning age of piglets from 4 to 7 weeks reduces stress, increases post-weaning feed intake but does not improve intestinal functionality. Animal 2010;4:1653-61.
    • (2010) Animal , vol.4 , pp. 1653-1661
    • van der Meulen, J.1    Koopmans, S.J.2    Dekker, R.A.3    Hoogendoorn, A.4
  • 17
    • 84872773618 scopus 로고    scopus 로고
    • Nutritional factors influencing intestinal health of the neonate
    • Jacobi SK, Odle J. Nutritional factors influencing intestinal health of the neonate. Adv Nutr 2012;3:687-96.
    • (2012) Adv Nutr , vol.3 , pp. 687-696
    • Jacobi, S.K.1    Odle, J.2
  • 20
    • 44449177607 scopus 로고    scopus 로고
    • Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation
    • Wang J, Chen L, Li P, Li X, Zhou H, Wang F, Li D, Yin Y, Wu G. Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation. J Nutr 2008;138:1025-32.
    • (2008) J Nutr , vol.138 , pp. 1025-1032
    • Wang, J.1    Chen, L.2    Li, P.3    Li, X.4    Zhou, H.5    Wang, F.6    Li, D.7    Yin, Y.8    Wu, G.9
  • 21
    • 64049119569 scopus 로고    scopus 로고
    • Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells
    • Li N, Neu J. Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells. J Nutr 2009;139:710-4.
    • (2009) J Nutr , vol.139 , pp. 710-714
    • Li, N.1    Neu, J.2
  • 22
    • 0038267446 scopus 로고    scopus 로고
    • Glutamine and barrier function in cultured Caco-2 epithelial cell monolayers
    • DeMarco VG, Li N, Thomas J, West CM, Neu J. Glutamine and barrier function in cultured Caco-2 epithelial cell monolayers. J Nutr 2003;133:2176-9.
    • (2003) J Nutr , vol.133 , pp. 2176-2179
    • DeMarco, V.G.1    Li, N.2    Thomas, J.3    West, C.M.4    Neu, J.5
  • 23
    • 0041706226 scopus 로고    scopus 로고
    • Glutamine supports recovery from loss of transepithelial resistance and increase of permeability induced by media change in Caco-2 cells
    • Li N, DeMarco VG, West CM, Neu J. Glutamine supports recovery from loss of transepithelial resistance and increase of permeability induced by media change in Caco-2 cells. J Nutr Biochem 2003;14:401-8.
    • (2003) J Nutr Biochem , vol.14 , pp. 401-408
    • Li, N.1    DeMarco, V.G.2    West, C.M.3    Neu, J.4
  • 24
    • 0029842804 scopus 로고    scopus 로고
    • Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs
    • Wu G, Meier SA, Knabe DA. Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J Nutr 1996;126:2578-84.
    • (1996) J Nutr , vol.126 , pp. 2578-2584
    • Wu, G.1    Meier, S.A.2    Knabe, D.A.3
  • 25
    • 4143100246 scopus 로고    scopus 로고
    • L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer
    • Seth A, Basuroy S, Sheth P, Rao RK. L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Am J Physiol Gastrointest Liver Physiol 2004;287: G510-7.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , pp. G510-G517
    • Seth, A.1    Basuroy, S.2    Sheth, P.3    Rao, R.K.4
  • 26
    • 22544451542 scopus 로고    scopus 로고
    • Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine
    • Basuroy S, Sheth P, Mansbach CM, Rao RK. Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine. Am J Physiol Gastrointest Liver Physiol 2005;289:G367-75.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289 , pp. G367-G375
    • Basuroy, S.1    Sheth, P.2    Mansbach, C.M.3    Rao, R.K.4
  • 27
    • 84903546400 scopus 로고    scopus 로고
    • Analysis of amino acid composition in proteins of animal tissues and foods as pre-column o-phthaldialdehyde derivatives by HPLC with fluorescence detection
    • Dai Z, Wu Z, Jia S, Wu G. Analysis of amino acid composition in proteins of animal tissues and foods as pre-column o-phthaldialdehyde derivatives by HPLC with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci 2014;964:116-27.
    • (2014) J Chromatogr B Analyt Technol Biomed Life Sci , vol.964 , pp. 116-127
    • Dai, Z.1    Wu, Z.2    Jia, S.3    Wu, G.4
  • 28
    • 84904763502 scopus 로고    scopus 로고
    • Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs
    • Wang W, Dai Z, Wu Z, Lin G, Jia S, Hu S, Dahanayaka S, Wu G. Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs. Amino Acids 2014;46:2037-45.
    • (2014) Amino Acids , vol.46 , pp. 2037-2045
    • Wang, W.1    Dai, Z.2    Wu, Z.3    Lin, G.4    Jia, S.5    Hu, S.6    Dahanayaka, S.7    Wu, G.8
  • 32
    • 0021327192 scopus 로고
    • A simple enzymatic method for the assay of urinary lactulose
    • Behrens RH, Docherty H, Elia M, Neale G. A simple enzymatic method for the assay of urinary lactulose. Clin Chim Acta 1984;137:361-7.
    • (1984) Clin Chim Acta , vol.137 , pp. 361-367
    • Behrens, R.H.1    Docherty, H.2    Elia, M.3    Neale, G.4
  • 33
    • 0036673381 scopus 로고    scopus 로고
    • Effect of weaning on small intestinal structure and function in the piglet
    • Gu X, Li D, She R. Effect of weaning on small intestinal structure and function in the piglet. Arch Tierernahr 2002;56:275-86.
    • (2002) Arch Tierernahr , vol.56 , pp. 275-286
    • Gu, X.1    Li, D.2    She, R.3
  • 34
    • 63649111659 scopus 로고    scopus 로고
    • Amino acids: metabolism, functions, and nutrition
    • Wu G. Amino acids: metabolism, functions, and nutrition. Amino Acids 2009;37:1-17.
    • (2009) Amino Acids , vol.37 , pp. 1-17
    • Wu, G.1
  • 35
    • 67349108393 scopus 로고    scopus 로고
    • Glutamine, arginine, and leucine signaling in the intestine
    • Marc Rhoads J,Wu G. Glutamine, arginine, and leucine signaling in the intestine. Amino Acids 2009;37:111-22.
    • (2009) Amino Acids , vol.37 , pp. 111-122
    • Marc Rhoads, J.1    Wu, G.2
  • 36
    • 84964548193 scopus 로고    scopus 로고
    • Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition
    • Wu G. Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition. J Anim Sci Biotechnol 2014;5:34.
    • (2014) J Anim Sci Biotechnol , vol.5 , pp. 34
    • Wu, G.1
  • 37
    • 84907231771 scopus 로고    scopus 로고
    • Glycine stimulates protein synthesis and inhibits oxidative stress in pig small intestinal epithelial cells
    • Wang W, Wu Z, Lin G, Hu S, Wang B, Dai Z, Wu G. Glycine stimulates protein synthesis and inhibits oxidative stress in pig small intestinal epithelial cells. J Nutr 2014;144:1540-8.
    • (2014) J Nutr , vol.144 , pp. 1540-1548
    • Wang, W.1    Wu, Z.2    Lin, G.3    Hu, S.4    Wang, B.5    Dai, Z.6    Wu, G.7
  • 38
    • 84882653868 scopus 로고    scopus 로고
    • Functional amino acids in nutrition and health
    • Wu G. Functional amino acids in nutrition and health. Amino Acids 2013;45:407-11.
    • (2013) Amino Acids , vol.45 , pp. 407-411
    • Wu, G.1
  • 40
    • 0028854404 scopus 로고
    • Luminal glutamine perfusion alters endotoxin-related changes in ileal permeability of the piglet
    • Dugan ME, McBurney MI. Luminal glutamine perfusion alters endotoxin-related changes in ileal permeability of the piglet. JPEN J Parenter Enteral Nutr 1995;19:83-7.
    • (1995) JPEN J Parenter Enteral Nutr , vol.19 , pp. 83-87
    • Dugan, M.E.1    McBurney, M.I.2
  • 41
    • 85047681696 scopus 로고    scopus 로고
    • Glutamine supplementation and deprivation: effect on artificially reared rat small intestinal morphology
    • Potsic B, Holliday N, Lewis P, Samuelson D, DeMarco V, Neu J. Glutamine supplementation and deprivation: effect on artificially reared rat small intestinal morphology. Pediatr Res 2002;52:430-6.
    • (2002) Pediatr Res , vol.52 , pp. 430-436
    • Potsic, B.1    Holliday, N.2    Lewis, P.3    Samuelson, D.4    DeMarco, V.5    Neu, J.6
  • 42
    • 0036370718 scopus 로고    scopus 로고
    • Glutamine: clinical applications and mechanisms of action
    • Neu J, DeMarco V, Li N. Glutamine: clinical applications and mechanisms of action. Curr Opin Clin Nutr Metab Care 2002;5:69-75.
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , pp. 69-75
    • Neu, J.1    DeMarco, V.2    Li, N.3
  • 43
    • 84894465013 scopus 로고    scopus 로고
    • Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets
    • Cabrera RA, Usry JL, Arrellano C, Nogueira ET, Kutschenko M, Moeser AJ, Odle J. Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets. J Anim Sci Biotechnol 2013;4:29.
    • (2013) J Anim Sci Biotechnol , vol.4 , pp. 29
    • Cabrera, R.A.1    Usry, J.L.2    Arrellano, C.3    Nogueira, E.T.4    Kutschenko, M.5    Moeser, A.J.6    Odle, J.7
  • 44
    • 0031877706 scopus 로고    scopus 로고
    • Glutamine reduces heat shock-induced cell death in rat intestinal epithelial cells
    • Chow A, Zhang R. Glutamine reduces heat shock-induced cell death in rat intestinal epithelial cells. J Nutr 1998;128:1296-301.
    • (1998) J Nutr , vol.128 , pp. 1296-1301
    • Chow, A.1    Zhang, R.2
  • 46
    • 0028280492 scopus 로고
    • Free and protein-bound amino acids in sow's colostrum and milk
    • Wu G, Knabe DA. Free and protein-bound amino acids in sow's colostrum and milk. J Nutr 1994;124:415-24.
    • (1994) J Nutr , vol.124 , pp. 415-424
    • Wu, G.1    Knabe, D.A.2
  • 50
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
    • Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 1998;141:199-208.
    • (1998) J Cell Biol , vol.141 , pp. 199-208
    • Haskins, J.1    Gu, L.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 52
    • 0037336565 scopus 로고    scopus 로고
    • Signalling to and from tight junctions
    • Matter K, Balda MS. Signalling to and from tight junctions. Nat Rev Mol Cell Biol 2003;4:225-36.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 225-236
    • Matter, K.1    Balda, M.S.2
  • 56
    • 0033783241 scopus 로고    scopus 로고
    • Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
    • Clarke H, Soler AP, Mullin JM. Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. J Cell Sci 2000;113:3187-96.
    • (2000) J Cell Sci , vol.113 , pp. 3187-3196
    • Clarke, H.1    Soler, A.P.2    Mullin, J.M.3
  • 57
    • 0023945559 scopus 로고
    • Effects of diacylglycerols on LLC-PK1 renal epithelia: similarity to phorbol ester tumor promoters
    • Mullin JM, McGinn MT. Effects of diacylglycerols on LLC-PK1 renal epithelia: similarity to phorbol ester tumor promoters. J Cell Physiol 1988;134:357-66.
    • (1988) J Cell Physiol , vol.134 , pp. 357-366
    • Mullin, J.M.1    McGinn, M.T.2
  • 58
    • 0034465652 scopus 로고    scopus 로고
    • Peripheral corticotropin-releasing factor and stress-stimulated colonic motor activity involve type 1 receptor in rats
    • Maillot C, Million M, Wei JY, Gauthier A, Tache Y. Peripheral corticotropin-releasing factor and stress-stimulated colonic motor activity involve type 1 receptor in rats. Gastroenterology 2000;119:1569-79.
    • (2000) Gastroenterology , vol.119 , pp. 1569-1579
    • Maillot, C.1    Million, M.2    Wei, J.Y.3    Gauthier, A.4    Tache, Y.5
  • 59
    • 84863111766 scopus 로고    scopus 로고
    • CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-αlpha
    • Overman EL, Rivier JE, Moeser AJ. CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-αlpha. PLoS ONE 2012;7:e39935.
    • (2012) PLoS ONE , vol.7
    • Overman, E.L.1    Rivier, J.E.2    Moeser, A.J.3


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