The biological stress of early weaned piglets

Journal of Animal Science and Biotechnology

Volumn 4, Issue 1, 2013, Pages

  Campbell, Joy M ^a   Crenshaw, Joe D ^a   Polo, Javier ^a  

^a APC Incorporated   (United States)

Author keywords

Biological stress; Intestine; Pig; Weaning

Indexed keywords

EID: 84887523490     PISSN: 16749782     EISSN: 20491891     Source Type: Journal    
DOI: 10.1186/2049-1891-4-19     Document Type: Review

References (26)

1. LeDividich J, Sève B. Effects of underfeeding during the weaning period on growth metabolism, and hormonal adjustments in the piglet. Dom Anim Endocrinol 2000, 19:63-74.
2. Spreeuwenberg MAM, Verdonk JMAJ, Gaskins HR, Verstegen MWA. Small intestine epithelial barrier function is compromised in pigs with low feed intake at weaning. J Nutr 2001, 131:1520-1527.
3. McCracken BA, Spurlock ME, Roos MA, Zuchermann FA, Gaskins HR. Weaning anorexia may contribute to local inflammation in the piglet small intestine. J Nutr 1999, 129:613-619.
4. Tokach MD, Goodband RD, Nelssen JL, Kats LJ. Influence of weaning weight and growth during the first week postweaning on subsequent pig performance 1992, 19-21. Proc of Kansas State University Swine Day.
5. Pluske JR, Hampson DJ, Williams IH. Factors influencing the structure and function of the small intestine in the weaned pigs: a review. Livest Prod Sci 1997, 51:215-236.
6. Boudry G, Peron V, Le Huerou-Luron I, Lalles JP, Sève B. Weaning induces both transient and long-lasting modifications of absorptive, secretory, and barrier properties of piglet intestine. J Nutr 2004, 134:2256-2262.
7. Hampson DJ. Alterations of piglet small intestine structure at weaning. Res Vet Sci 1986, 40:32-40.
8. Montagne L, Boudry G, Favier C, Le Huerou-Luron I, Lalles JP, Seve B. Main intestinal markers associated with the changes in gut architecture and function in piglets after weaning. Br J Nutr 2007, 97:45-57. 10.1017/S000711450720580X, 17217559.
9. Lalles J, Boudry G, Favier C, LeFloc N, Luron I, Montagne L, Oswald IP, Pié S, Piel C, Sève B. Gut function and dysfunction in young pigs: physiology. Anim Res 2004, 53:301-316.
10. Lalles J. Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet. Nutr Rev 2010, 68:323-332. 10.1111/j.1753-4887.2010.00292.x, 20536777.
11. Lackeyram D, Yang C, Archbold T, Swanson KC, Fan MZ. Early weaning reduces small intestinal alkaline phosphatase expression in pigs. J Nutr 2010, 140:461-468. 10.3945/jn.109.117267, 20089775.
12. Moeser AJ, Vander Klok C, Ryan KA, Wooten JG, Little JG, Cook VL, Blisklager AT. Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig. Am J Physiol Gastrointest Liver Physiol 2007, 292:G173-G181.
13. Nabuurs MJA, Hoogendoorn A, Van Zijderveld FG. Effects of weaning and enterotoxigenic Escherichia coli on net absorption in the small intestine of pigs. Res Vet Sci 1994, 56:379-385. 10.1016/0034-5288(94)90156-2, 8073191.
14. Moeser AJ, Ryan KA, Nighot PK, Blikslager AT. Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs. Am J Physiol Gastrointest Liver Physiol 2007, 293:G413-G421. 10.1152/ajpgi.00304.2006, 17525151.
15. Smith F, Clark JE, Overman BL, Tozel CC, Huang JH, Rivier JEF, Blisklager AT, Moeser AJ. Early weaning stress impairs development of mucosal barrier function in the porcine intestine. Am J Physiol Gastrointest Liver Physiol 2010, 298:G352-G363. 10.1152/ajpgi.00081.2009, 2838512, 19926814.
16. McKay DM, Baird AW. Cytokine regulation of epithelial permeability and ion transport. Gut 1999, 44:282-289.
17. Pié S, Lallès JP, Blazy F, Laffitte J, Sève B, Oswald IP. Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets. J Nutr 2004, 134:641-647.
18. Johnson RW. Inhibition of growth by pro-inflammatory cytokines: An integrated view. J Anim Sci 1997, 75:1244-1255.
19. Spurlock ME. Regulation of metabolism and growth during immune challenge: An overview of cytokine function. J Anim Sci 1997, 75:1773-1783.
20. Burrin D, Stoll B. Enhancing intestinal function to improve growth and efficiency 2003, 121-137. 9th International Symposium on Digestive Physiology of Pigs.
21. Williams NH, Stahly TS, Zimmerman DR. Effect of level of chronic immune system activation on the growth and dietary lysine needs of pigs fed from 6 to 112 kg. J Anim Sci 1997, 75:2481-2496.
22. Williams NH, Stahly TS, Zimmerman DR. Effect of chronic immune system activation on body nitrogen retention, partial efficiency of lysine utilization, and lysine needs of pigs. J Anim Sci 1997, 75:2472-2480.
23. Williams NH, Stahly TS, Zimmerman DR. Effect of chronic immune system activation on rate, efficiency, and composition of growth and lysine needs of pigs fed from 6 to 27 kg. J Anim Sci 1997, 75:2463-2471.
24. Feder ME, Hofmann GE. Heat-shock proteins, molecular chaperones, and the stress response: Evolutionary and ecological physiology. Annu Rev Physiol 1999, 61:243-282. 10.1146/annurev.physiol.61.1.243, 10099689.
25. David JC, Grongnet JF, Lalles JP. Weaning affects the expression of heat shock proteins in different regions of the gastrointestinal tract of piglets. J Nutr 2002, 132:2551-2561.
26. Malago JJ, Koninkx JFJG, van Dijk JE. The heat shock response and cytoprotection of the intestinal epithelium. Cell Stress Chaperones 2002, 7:191-199. 10.1379/1466-1268(2002)007<0191:THSRAC>2.0.CO;2, 514817, 12380687.