Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Nature Communications

Volumn 5, Issue , 2014, Pages

  Postmus, Iris ^a,b   Trompet, Stella ^a   Deshmukh, Harshal A ^c   Barnes, Michael R ^d,e   Li, Xiaohui ^f   Warren, Helen R ^d,e   Chasman, Daniel I ^g,h   Zhou, Kaixin ^c   Arsenault, Benoit J ⁱ   Donnelly, Louise A ^c   Wiggins, Kerri L ^j   Avery, Christy L ^k   Griffin, Paula ^l   Feng, Qiping ^m   Taylor, Kent D ^f   Li, Guo ^j   Evans, Daniel S ⁿ   Smith, Albert V ^o,p   De Keyser, Catherine E ^q,r   Johnson, Andrew D ^s   De Craen, Anton J M ^a,b   Stott, David J ^t   Buckley, Brendan M ^u   Ford, Ian ^t   Westendorp, Rudi G J ^a,b,v   Slagboom, P Eline ^a,b   Sattar, Naveed ^w   Munroe, Patricia B ^d,e   Sever, Peter ^x   Poulter, Neil ^x   Stanton, Alice ^y,z   Shields, Denis C ^aa   O'Brien, Eoin ^aa   Shaw Hawkins, Sue ^d,e   Ida Chen, Y D ^f   Nickerson, Deborah A ^ab   Smith, Joshua D ^ab   Dubé, Marie Pierre ⁱ   Boekholdt, S Matthijs ^ac   Hovingh, G Kees ^ac   Kastelein, John J P ^ac   McKeigue, Paul M ^ad   Betteridge, John ^ae   Neil, Andrew ^af   Durrington, Paul N ^ag   Doney, Alex ^c   Carr, Fiona ^c   Morris, Andrew ^c   McCarthy, Mark I ^ah,ai,aj   Groop, Leif ^ak   Ahlqvist, Emma ^ak   Barroso, Ines ^bg   Blackwell, Jenefer M ^bh,bi   Bramon, Elvira ^bj   Brown, Matthew A ^bk   Casas, Juan P ^ae,bl   Corvin, Aiden ^bm   Deloukas, Panos ^bg   Duncanson, Audrey ^bg   Jankowski, Janusz ^e,af,bn   Markus, Hugh S ^bo   Mathew, Christopher G ^bp   Palmer, Colin N A ^c   Plomin, Robert ^bj   Rautanen, Anna ^ai   Sawcer, Stephen J ^bq   Trembath, Richard C ^bp   Viswanathan, Ananth C ^br   Wood, Nicholas W ^bs   Spencer, Chris C A ^ai   Band, Gavin ^ai   Bellenguez, Céline ^ai   Freeman, Colin ^ai   Hellenthal, Garrett ^ai   Giannoulatou, Eleni ^ai   Pirinen, Matti ^ai   Pearson, Richard ^ai   Strange, Amy ^ai   Su, Zhan ^ai   Vukcevic, Damjan ^ai   Donnelly, Peter ^af,ai   Langford, Cordelia ^bg   Hunt, Sarah E ^bg   Edkins, Sarah ^bg   Gwilliam, Rhian ^bg   Blackburn, Hannah ^bg   Bumpstead, Suzannah J ^bg   Dronov, Serge ^bg   Gillman, Matthew ^bg   Gray, Emma ^bg   Hammond, Naomi ^bg   Jayakumar, Alagurevathi ^bg   McCann, Owen T ^bg   Liddle, Jennifer ^bg   Potter, Simon C ^bg   Ravindrarajah, Radhi ^bg   Ricketts, Michelle ^bg   Waller, Matthew ^bg   Weston, Paul ^bg   Widaa, Sara ^bg   Whittaker, Pamela ^bg   Bis, Joshua C ^j   Rice, Kenneth ^ab   Smith, Nicholas L ^ab,al,am   Lumley, Thomas ^j,an   Whitsel, Eric A ^k,ao   Stürmer, Til ^k   Boerwinkle, Eric ^ap   Ngwa, Julius S ^l   O'Donnell, Christopher J ^s,aq,ar   Vasan, Ramachandran S ^as   Wei, Wei Qi ^at   Wilke, Russell A ^au   Liu, Ching Ti ^l   Sun, Fangui ^l   Guo, Xiuqing ^f   Heckbert, Susan R ^j,ab,al   Post, Wendy ^av   Sotoodehnia, Nona ^j   Arnold, Alice M ^ab   Stafford, Jeanette M ^aw   Ding, Jingzhong ^aw   Herrington, David M ^aw   Kritchevsky, Stephen B ^aw   Eiriksdottir, Gudny ^o   Launer, Leonore J ^ax   Harris, Tamara B ^ax   Chu, Audrey Y ^g   Giulianini, Franco ^g   MacFadyen, Jean G ^g   Barratt, Bryan J ^ay   Nyberg, Fredrik ^az,ba   Stricker, Bruno H ^q,r   Uitterlinden, André G ^b,q   Hofman, Albert ^b,q   Rivadeneira, Fernando ^q   Emilsson, Valur ^o   Franco, Oscar H ^q   Ridker, Paul M ^g   Gudnason, Vilmundur ^o,p   Liu, Yongmei ^aw   Denny, Joshua C ^m,at   Ballantyne, Christie M ^bb   Rotter, Jerome I ^f   Cupples, L Adrienne ^l,s   Psaty, Bruce M ^j,ab,al   Tardif, Jean Claude ⁱ   Colhoun, Helen M ^c,bc   Hitman, Graham ^d   Krauss, Ronald M ^bd   Jukema, J Wouter ^a,be,bf   Caulfield, Mark J ^d,e   more..

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Consortium for Healthy Ageing   (Netherlands)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f HARBOR UCLA MEDICAL CENTER   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ MONTREAL HEART INSTITUTE   (Canada)

^j UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^k IL   (United States)

^l BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^m VANDERBILT UNIVERSITY   (United States)

ⁿ CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^o ICELANDIC HEART ASSOCIATION   (Iceland)

^p UNIVERSITY OF ICELAND   (Iceland)

^q ERASMUS MEDICAL CENTER   (Netherlands)

^r The Health Care Inspectorate (IGZ)   (Netherlands)

^s FRAMINGHAM HEART STUDY   (United States)

^t UNIVERSITY OF GLASGOW   (United Kingdom)

^u UNIVERSITY COLLEGE CORK   (Ireland)

^v Leyden Academy of Vitality and Ageing   (Netherlands)

^w UNIVERSITY OF GLASGOW   (United Kingdom)

^x IMPERIAL COLLEGE LONDON   (United Kingdom)

^y ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^z BEAUMONT HOSPITAL   (Ireland)

^aa UNIVERSITY COLLEGE DUBLIN   (Ireland)

^ab UNIVERSITY OF WASHINGTON   (United States)

^ac ACADEMIC MEDICAL CENTER   (Netherlands)

^ad UNIVERSITY OF EDINBURGH   (United Kingdom)

^ae UNIVERSITY COLLEGE LONDON   (United Kingdom)

^af UNIVERSITY OF OXFORD   (United Kingdom)

^ag UNIVERSITY OF MANCHESTER   (United Kingdom)

^ah UNIVERSITY OF OXFORD   (United Kingdom)

^ai UNIVERSITY OF OXFORD   (United Kingdom)

^aj CHURCHILL HOSPITAL   (United Kingdom)

^ak LUND UNIVERSITY   (Sweden)

^al CENTER FOR HEALTH STUDIES   (United States)

^am DEPARTMENT OF VETERANS AFFAIRS   (United States)

^an UNIVERSITY OF AUCKLAND   (New Zealand)

^ao UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^ap UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^aq MASSACHUSETTS GENERAL HOSPITAL   (United States)

^ar NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^as BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^at VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^au Department of Internal Medicine Center for IMAGENETICS Sanford Healthcare   (United States)

^av JOHNS HOPKINS UNIVERSITY   (United States)

^aw WAKE FOREST SCHOOL OF MEDICINE   (United States)

^ax NATIONAL INSTITUTE ON AGING   (United States)

^ay ASTRAZENECA   (United Kingdom)

^az ASTRAZENECA R AND D   (Sweden)

^ba UNIVERSITY OF GOTHENBURG   (Sweden)

^bb BAYLOR COLLEGE OF MEDICINE   (United States)

^bc UNIVERSITY OF DUNDEE   (United Kingdom)

^bd CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^be Durrer Center for Cardiogenetic Research   (Netherlands)

^bf ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^bg WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^bh UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^bi UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^bj KING'S COLLEGE LONDON   (United Kingdom)

^bk UNIVERSITY OF QUEENSLAND   (Australia)

^bl LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^bm TRINITY COLLEGE DUBLIN   (Ireland)

^bn LEICESTER ROYAL INFIRMARY   (United Kingdom)

^bo ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^bp KING'S COLLEGE LONDON   (United Kingdom)

^bq UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^br MOORFIELDS EYE HOSPITAL   (United Kingdom)

^bs UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; ATORVASTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PRAVASTATIN; PROTEIN BCL 3; ROSUVASTATIN; SIMVASTATIN; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1B1; SORTILIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR ER81; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

GENETIC ANALYSIS; GENETIC VARIATION; GENOME; META-ANALYSIS;

ARTICLE; CHOLESTEROL BLOOD LEVEL; EFFECT SIZE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; META ANALYSIS; PHARMACOGENETICS; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; GENETICS; GENOME-WIDE ASSOCIATION STUDY;

CHOLESTEROL, LDL; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; PHARMACOGENETICS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84919752308     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6068     Document Type: Article

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