Short and efficient syntheses of protoberberine alkaloids using palladium-catalyzed enolate arylation

Angewandte Chemie - International Edition

Volumn 53, Issue 52, 2014, Pages 14555-14558

  Gatland, Alice E ^a   Pilgrim, Ben S ^a   Procopiou, Panayiotis A ^b   Donohoe, Timothy J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Alkaloids; Natural products; Palladium; Synthetic methods; Total synthesis

Indexed keywords

AROMATIC COMPOUNDS; CHEMICAL COMPOUNDS; CHEMICAL REACTIONS; DRUG PRODUCTS; ELECTRONIC PROPERTIES; KETONES; METABOLITES; OLEFINS; PALLADIUM; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

EFFICIENT SYNTHESIS; ELECTROPHILIC AROMATIC SUBSTITUTIONS; FUNCTIONALIZATIONS; NATURAL PRODUCTS; PALLADIUM-CATALYZED; PROTOBERBERINE ALKALOIDS; SYNTHETIC METHODS; TOTAL SYNTHESIS;

ALKALOIDS;

BERBERINE DERIVATIVE; BIOLOGICAL PRODUCT; ISOQUINOLINE; ISOQUINOLINE DERIVATIVE; PALLADIUM;

CATALYSIS; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

BERBERINE ALKALOIDS; BIOLOGICAL PRODUCTS; CATALYSIS; ISOQUINOLINES; PALLADIUM; STEREOISOMERISM;

EID: 84919686096     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201409164     Document Type: Article

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