메뉴 건너뛰기




Volumn 8, Issue 11, 2009, Pages 5296-5304

Proteomic analysis reveals a synergistic mechanism of fluconazole and berberine against fluconazole-resistant Candida albicans: Endogenous ROS augmentation

Author keywords

Berberine; Candida albicans; Fluconazole resistance; Proteomics; Synergistic mechanism

Indexed keywords

ADENOSINE TRIPHOSPHATE; ASCORBIC ACID; BERBERINE; FLUCONAZOLE; GLUTATHIONE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE;

EID: 70449412365     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr9005074     Document Type: Article
Times cited : (101)

References (47)
  • 1
    • 0029959130 scopus 로고    scopus 로고
    • Epidemiology of nosocomial fungal-infections
    • Fridkin, S. K.; Jarvis, W. R. Epidemiology of nosocomial fungal-infections. Clin. Microbiol. Rev. 1996, 9, 499-511.
    • (1996) Clin. Microbiol. Rev. , vol.9 , pp. 499-511
    • Fridkin, S.K.1    Jarvis, W.R.2
  • 3
    • 0030017115 scopus 로고    scopus 로고
    • Nosocomial candidiasis: Emerging species, reservoirs, and modes of transmission
    • Pfaller, M. A. Nosocomial candidiasis: emerging species, reservoirs, and modes of transmission. Clin. Infect. Dis. 1996, 22 (Suppl. 2), S89-S94.
    • (1996) Clin. Infect. Dis. , vol.22 , Issue.SUPPL. 2
    • Pfaller, M.A.1
  • 4
    • 0036174370 scopus 로고    scopus 로고
    • The direct cost and incidence of systemic fungal infections
    • DOI 10.1046/j.1524-4733.2002.51108.x
    • Wilson, L. S.; Reyes, C. M.; Stolpman, M.; Speckman, J.; Allen, K.; Beney, J. The direct cost and incidence of systemic fungal infections. Value Health 2002, 5, 26-34. (Pubitemid 34160368)
    • (2002) Value in Health , vol.5 , Issue.1 , pp. 26-34
    • Wilson, L.S.1    Reyes, C.M.2    Stolpman, M.3    Speckman, J.4    Allen, K.5    Beney, J.6
  • 5
    • 0036208102 scopus 로고    scopus 로고
    • In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry
    • DOI 10.1128/AAC.46.4.1046-1052.2002
    • Kohli, A.; Smriti, Mukhopadhyay, K.; Rattan, A.; Prasad, R. In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry. Antimicrob. Agents Chemother. 2002, 46, 1046-1052. (Pubitemid 34260349)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.4 , pp. 1046-1052
    • Kohli, A.1    Smriti2    Mukhopadhyay, K.3    Rattan, A.4    Prasad, R.5
  • 7
    • 0025257110 scopus 로고
    • Pharmaco-kinetics and tissue penetration of fluconazole in humans
    • Brammer, K. W.; Farrow, P. R.; Faulkner, J. K. Pharmaco-kinetics and tissue penetration of fluconazole in humans. Rev. Infect. Dis. 1990, 12 (Suppl. 3), S318-S326.
    • (1990) Rev. Infect. Dis. , vol.12 , Issue.SUPPL. 3
    • Brammer, K.W.1    Farrow, P.R.2    Faulkner, J.K.3
  • 9
    • 0027739728 scopus 로고
    • Molecular genetic analysis of azole antifungal mode of action
    • Kelly, S. L.; Arnoldi, A.; Kelly, D. E. Molecular genetic analysis of azole antifungal mode of action. Biochem. Soc. Trans. 1993, 21, 1034-1038.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 1034-1038
    • Kelly, S.L.1    Arnoldi, A.2    Kelly, D.E.3
  • 11
    • 0027253440 scopus 로고
    • Fluconazole resistance in Candida in patients with AIDSsa therapeutic approach
    • Ng, T. T.; Denning, D. W. Fluconazole resistance in Candida in patients with AIDSsa therapeutic approach. J. Infect. 1993, 26, 117-125.
    • (1993) J. Infect. , vol.26 , pp. 117-125
    • Ng, T.T.1    Denning, D.W.2
  • 12
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • White, T. C.; Marr, K. A.; Bowden, R. A. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin. Microbiol. Rev. 1998, 11, 382-402. (Pubitemid 28197359)
    • (1998) Clinical Microbiology Reviews , vol.11 , Issue.2 , pp. 382-402
    • White, T.C.1    Marr, K.A.2    Bowden, R.A.3
  • 14
    • 41649086533 scopus 로고    scopus 로고
    • Drug resistance: The fight against fungi
    • Goffeau, A. Drug resistance: the fight against fungi. Nature 2008, 452, 541-542.
    • (2008) Nature , vol.452 , pp. 541-542
    • Goffeau, A.1
  • 15
    • 47849102650 scopus 로고    scopus 로고
    • Outwitting multidrug resistance to antifungals
    • Monk, B. C.; Goffeau, A. Outwitting multidrug resistance to antifungals. Science 2008, 321, 367-369.
    • (2008) Science , vol.321 , pp. 367-369
    • Monk, B.C.1    Goffeau, A.2
  • 16
    • 33644650719 scopus 로고    scopus 로고
    • Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole
    • Quan, H.; Cao, Y. Y.; Xu, Z.; Zhao, J. X.; Gao, P. H.; Qin, H. F.; Jiang, Y. Y. Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole. Antimicrob. Agents Chemother. 2006, 50, 1096-1099.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1096-1099
    • Quan, H.1    Cao, Y.Y.2    Xu, Z.3    Zhao, J.X.4    Gao, P.H.5    Qin, H.F.6    Jiang, Y.Y.7
  • 17
    • 0020047678 scopus 로고
    • Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins
    • Sack, R. B.; Froehlich, J. L. Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infect. Immun. 1982, 35, 471-475.
    • (1982) Infect. Immun. , vol.35 , pp. 471-475
    • Sack, R.B.1    Froehlich, J.L.2
  • 19
    • 0038631572 scopus 로고    scopus 로고
    • Sequential fractionation and two-dimensional gel analysis unravels the complexity of the dimorphic fungus Candida albicans cell wall proteome
    • Pitarch, A.; Sanchez, M.; Nombela, C.; Gil, C. Sequential fractionation and two-dimensional gel analysis unravels the complexity of the dimorphic fungus Candida albicans cell wall proteome. Mol. Cell. Proteomics 2002, 1, 967-982.
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 967-982
    • Pitarch, A.1    Sanchez, M.2    Nombela, C.3    Gil, C.4
  • 21
    • 0025362399 scopus 로고
    • A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae
    • Schmitt, M. E.; Brown, T. A.; Trumpower, B. L. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 1990, 18, 3091-3092. (Pubitemid 20178191)
    • (1990) Nucleic Acids Research , vol.18 , Issue.10 , pp. 3091-3092
    • Schmitt, M.E.1    Brown, T.A.2    Trumpower, B.L.3
  • 22
    • 0030612749 scopus 로고    scopus 로고
    • JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: Implications for studies on mitochondrial functionality during apoptosis
    • Salvioli, S.; Ardizzoni, A.; Franceschi, C.; Cossarizza, A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997, 411, 77-82.
    • (1997) FEBS Lett. , vol.411 , pp. 77-82
    • Salvioli, S.1    Ardizzoni, A.2    Franceschi, C.3    Cossarizza, A.4
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 25
    • 0033434080 scopus 로고    scopus 로고
    • Probability-based protein identification by searching sequence databases using mass spectrometry data
    • Perkins, D. N.; Pappin, D. J.; Creasy, D. M.; Cottrell, J. S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20, 3551-3567.
    • (1999) Electrophoresis , vol.20 , pp. 3551-3567
    • Perkins, D.N.1    Pappin, D.J.2    Creasy, D.M.3    Cottrell, J.S.4
  • 26
    • 0033900334 scopus 로고    scopus 로고
    • Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae
    • Kontoyiannis, D. P. Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae. J. Antimicrob. Chemother. 2000, 46, 191-197.
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 191-197
    • Kontoyiannis, D.P.1
  • 27
    • 34250841813 scopus 로고    scopus 로고
    • Proteomic analysis reveals a metabolism shift in a laboratory fluconazole-resistant Candida albicans strain
    • Yan, L.; Zhang, J. D.; Cao, Y. B.; Gao, P. H.; Jiang, Y. Y. Proteomic analysis reveals a metabolism shift in a laboratory fluconazole-resistant Candida albicans strain. J. Proteome Res. 2007, 6, 2248-2256.
    • (2007) J. Proteome Res. , vol.6 , pp. 2248-2256
    • Yan, L.1    Zhang, J.D.2    Cao, Y.B.3    Gao, P.H.4    Jiang, Y.Y.5
  • 28
    • 0036554502 scopus 로고    scopus 로고
    • Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways
    • DOI 10.1080/10715760290021225
    • Staniek, K.; Gille, L.; Kozlov, A. V.; Nohl, H. Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways. Free Radical Res. 2002, 36, 381-387. (Pubitemid 35154086)
    • (2002) Free Radical Research , vol.36 , Issue.4 , pp. 381-387
    • Staniek, K.1    Gille, L.2    Kozlov, A.V.3    Nohl, H.4
  • 29
    • 0020672274 scopus 로고
    • Generation of hydrogen peroxide by Candida albicans and influence on murine polymorphonuclear leukocyte activity
    • Danley, D. L.; Hilger, A. E.; Winkel, C. A. Generation of hydrogen peroxide by Candida albicans and influence on murine polymorphonuclear leukocyte activity. Infect. Immun. 1983, 40, 97-102.
    • (1983) Infect. Immun. , vol.40 , pp. 97-102
    • Danley, D.L.1    Hilger, A.E.2    Winkel, C.A.3
  • 30
    • 0042433242 scopus 로고    scopus 로고
    • 2 production by membrane potential and NAD(P)H redox state
    • 2 production by membrane potential and NAD(P)H redox state. J. Neurochem. 2003, 86, 1101-1107.
    • (2003) J. Neurochem. , vol.86 , pp. 1101-1107
    • Starkov, A.A.1    Fiskum, G.2
  • 31
  • 32
    • 33750201854 scopus 로고    scopus 로고
    • Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation
    • Ruy, F.; Vercesi, A. E.; Kowaltowski, A. J. Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation. J. Bioenerg. Biomembr. 2006, 38, 129-135.
    • (2006) J. Bioenerg. Biomembr. , vol.38 , pp. 129-135
    • Ruy, F.1    Vercesi, A.E.2    Kowaltowski, A.J.3
  • 34
    • 33947403221 scopus 로고    scopus 로고
    • Proteomic analysis of the oxidative stress response in Candida albicans
    • DOI 10.1002/pmic.200600575
    • Kusch, H.; Engelmann, S.; Albrecht, D.; Morschhäuser, J.; Hecker, M. Proteomic analysis of the oxidative stress response in Candida albicans. Proteomics 2007, 7, 686-697. (Pubitemid 46450647)
    • (2007) Proteomics , vol.7 , Issue.5 , pp. 686-697
    • Kusch, H.1    Engelmann, S.2    Albrecht, D.3    Morschhauser, J.4    Hecker, M.5
  • 35
    • 39849102492 scopus 로고    scopus 로고
    • A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases
    • DOI 10.1016/j.ijmm.2007.03.020, PII S1438422107000872
    • Kusch, H.; Engelmann, S.; Bode, R.; Albrecht, D.; Morschhäuser, J.; Hecker, M. A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases. Int. J. Med. Microbiol. 2007, 298, 291-318. (Pubitemid 351318360)
    • (2008) International Journal of Medical Microbiology , vol.298 , Issue.3-4 , pp. 291-318
    • Kusch, H.1    Engelmann, S.2    Bode, R.3    Albrecht, D.4    Morschhauser, J.5    Hecker, M.6
  • 36
    • 33746061278 scopus 로고    scopus 로고
    • Candida albicans SNO1 and SNZ1 expressed in stationary-phase planktonic yeast cells and base of biofilm
    • Uppuluri, P.; Sarmah, B.; Chaffin, W. L. Candida albicans SNO1 and SNZ1 expressed in stationary-phase planktonic yeast cells and base of biofilm. Microbiology 2006, 152, 2031-2038.
    • (2006) Microbiology , vol.152 , pp. 2031-2038
    • Uppuluri, P.1    Sarmah, B.2    Chaffin, W.L.3
  • 37
    • 18844393429 scopus 로고    scopus 로고
    • Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans
    • Liu, T. T.; Lee, R. B.; Barker, K. S.; Lee, R. E.; Wei, L.; Homayouni, R.; Rogers, P. D. Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. Antimicrob. Agents Chemother. 2005, 49, 2226-2236.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2226-2236
    • Liu, T.T.1    Lee, R.B.2    Barker, K.S.3    Lee, R.E.4    Wei, L.5    Homayouni, R.6    Rogers, P.D.7
  • 39
    • 18844462400 scopus 로고    scopus 로고
    • Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes
    • Copping, V. M.; Barelle, C. J.; Hube, B.; Gow, N. A.; Brown, A. J.; Odds, F. C. Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. J. Antimicrob. Chemother. 2005, 55, 645-654.
    • (2005) J. Antimicrob. Chemother. , vol.55 , pp. 645-654
    • Copping, V.M.1    Barelle, C.J.2    Hube, B.3    Gow, N.A.4    Brown, A.J.5    Odds, F.C.6
  • 40
    • 34147124324 scopus 로고    scopus 로고
    • Integrated proteomics and genomics strategies bring new insight into Candida albicans response upon macrophage interaction
    • DOI 10.1074/mcp.M600210-MCP200
    • Fernández-Arenas, E.; Cabezón, V.; Bermejo, C.; Arroyo, J.; Nombela, C.; Diez-Orejas, R.; Gil, C. Integrated Proteomics and Genomics Strategies Bring New Insight into Candida albicans Response upon Macrophage Interaction. Mol. Cell. Proteomics 2007, 6, 460-478. (Pubitemid 46554541)
    • (2007) Molecular and Cellular Proteomics , vol.6 , Issue.3 , pp. 460-478
    • Fernandez-Arenas, E.1    Cabezon, V.2    Bermejo, C.3    Arroyo, J.4    Nombela, C.5    Diez-Orejas, R.6    Gil, C.7
  • 41
    • 0032953701 scopus 로고    scopus 로고
    • Differential inhibitory sffects of protoberberines on sterol and chitin biosyntheses in Candida albicans
    • Park, K. S.; Kang, K. C.; Kim, J. H.; Adams, D. J.; Jhong, T. N.; Paik, Y. K. Differential inhibitory sffects of protoberberines on sterol and chitin biosyntheses in Candida albicans. J. Antimicrob. Chemother. 1999, 43, 667-674.
    • (1999) J. Antimicrob. Chemother. , vol.43 , pp. 667-674
    • Park, K.S.1    Kang, K.C.2    Kim, J.H.3    Adams, D.J.4    Jhong, T.N.5    Paik, Y.K.6
  • 42
    • 0025653034 scopus 로고
    • Effects of crude drugs and berberine hydrochloride on the activities of fungi
    • Nakamoto, K.; Sadamori, S.; Hamada, T. Effects of crude drugs and berberine hydrochloride on the activities of fungi. J. Prosthet. Dent. 1990, 64, 691-694.
    • (1990) J. Prosthet. Dent. , vol.64 , pp. 691-694
    • Nakamoto, K.1    Sadamori, S.2    Hamada, T.3
  • 43
    • 0043012002 scopus 로고    scopus 로고
    • Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids
    • Vollekova, A.; Kost'alova, D.; Kettmann, V.; Toth, J. Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids. Phytother. Res. 2003, 17, 834-837.
    • (2003) Phytother. Res. , vol.17 , pp. 834-837
    • Vollekova, A.1    Kost'alova, D.2    Kettmann, V.3    Toth, J.4
  • 44
    • 0002515716 scopus 로고    scopus 로고
    • Antimicrobial combinations
    • 4th ed.; Lorian, V., Ed.; The Williams & Wilkins Co.: Baltimore, MD
    • Eliopoulos, G. M.; Moellering, R. C., Jr. Antimicrobial combinations. In Antibiotics in Laboratory Medicine, 4th ed.; Lorian, V., Ed.; The Williams & Wilkins Co.: Baltimore, MD, 1996; pp 330-396.
    • (1996) Antibiotics in Laboratory Medicine , pp. 330-396
    • Eliopoulos, G.M.1    Moellering Jr., R.C.2
  • 45
    • 70449407726 scopus 로고    scopus 로고
    • National Committee for Clinical and Laboratory Standards. Approved standard M27-A. National Committee for Clinical and Laboratory Standards: Wayne, PA
    • National Committee for Clinical and Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts, Vol.17, No.9. Approved standard M27-A. National Committee for Clinical and Laboratory Standards: Wayne, PA, 1997.
    • (1997) Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts , vol.17 , Issue.9
  • 46
    • 0038601510 scopus 로고    scopus 로고
    • Synergy, antagonism, and what the chequerboard puts between them
    • Odds, F. C. Synergy, antagonism, and what the chequerboard puts between them. J. Antimicrob. Chemother. 2003, 52, 1.
    • (2003) J. Antimicrob. Chemother. , vol.52 , pp. 1
    • Odds, F.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.