Synthesis and structure-activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 16, 2008, Pages 4675-4677

  Yang, Peng ^a   Song, Dan Qing ^a   Li, Ying Hong ^a   Kong, Wei Jia ^a   Wang, Yan Xiang ^a   Gao, Li Mei ^a   Liu, Shu Yu ^a   Cao, Rui Qiang ^a   Jiang, Jian Dong ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Berberine; Blood cholesterol; Low density lipoprotein receptor; Pseudoberberine; Structure activity relationship

Indexed keywords

BERBERINE DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN RECEPTOR;

ARTICLE; CELL STRAIN HEPG2; DRUG ACTIVITY; DRUG DETERMINATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; UPREGULATION;

BENZENE; BERBERINE; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; HYPERCHOLESTEROLEMIA; IONS; LIPIDS; MODELS, CHEMICAL; RECEPTORS, LDL; RNA STABILITY; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; UP-REGULATION;

EID: 48649101917     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.005     Document Type: Article

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