Th1/Th17 plasticity is a marker of advanced B cell autoimmunity and impaired glucose tolerance in humans

Journal of Immunology

Volumn 194, Issue 1, 2015, Pages 68-75

  Reinert Hartwall, Linnea ^a   Honkanen, Jarno ^a   Salo, Harri M ^a   Nieminen, Janne K ^a   Luopajärvi, Kristiina ^a,b   Härkönen, Taina ^b   Veijola, Riitta ^c   Simell, Olli ^d   Ilonen, Jorma ^d,e   Peet, Aleksandr ^f   Tillmann, Vallo ^f   Knip, Mikael ^b,g,h   Vaarala, Outi ^b,i  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c OULU UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f UNIVERSITY OF TARTU   (Estonia)

^g FOLKHÄLSAN RESEARCH CENTER   (Finland)

^h TAMPERE UNIVERSITY HOSPITAL   (Finland)

ⁱ ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLUCOSE; HEMOGLOBIN A1C; INTERLEUKIN 17; AUTOANTIBODY; BIOLOGICAL MARKER; IKAROS TRANSCRIPTION FACTOR; IKZF2 PROTEIN, HUMAN; IL9 PROTEIN, HUMAN; INTERLEUKIN 9;

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN CELL; IMPAIRED GLUCOSE TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; UPREGULATION; BIOSYNTHESIS; BLOOD; CELL CULTURE; DISEASE COURSE; GLUCOSE INTOLERANCE; IMMUNOLOGY; PRESCHOOL CHILD;

AUTOANTIBODIES; AUTOIMMUNITY; BIOMARKERS; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; GLUCOSE INTOLERANCE; HUMANS; IKAROS TRANSCRIPTION FACTOR; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-9; MALE; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS; UP-REGULATION;

EID: 84919683552     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401653     Document Type: Article

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