Overelaborated synaptic architecture and reduced synaptomatrix glycosylation in a Drosophila classic galactosemia disease model

DMM Disease Models and Mechanisms

Volumn 7, Issue 12, 2014, Pages 1365-1378

  Jumbo Lucioni, Patricia ^a   Parkinson, William ^a   Broadie, Kendal ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Congenital disorder of glycosylation (CDG); Galactokinase; HSPG; Neuromuscular junction; Sugarless; Synaptogenesis; Trans synaptic signaling; WNT

Indexed keywords

GALACTOKINASE; GALACTOSE; GALACTOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; HORSERADISH PEROXIDASE; LECTIN; N ACETYLGALACTOSAMINE; PROTEOHEPARAN SULFATE; URIDINE DIPHOSPHATE GLUCOSE DEHYDROGENASE; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DROSOPHILA; ENZYME ACTIVITY; GALACTOSEMIA; GENE; GENE IDENTIFICATION; GENE MUTATION; GLYCOSYLATION; MORPHOGENESIS; NEUROMUSCULAR SYNAPSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SYNAPTIC MEMBRANE; SYNAPTOGENESIS; ANIMAL; ANIMAL BEHAVIOR; CHEMISTRY; GENETICS; GENOTYPE; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY; RNA INTERFERENCE; SYNAPSE; TRANSGENIC ANIMAL;

ARMORACIA RUSTICANA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DROSOPHILA; GALACTOSE; GALACTOSEMIAS; GENOTYPE; GLYCOSYLATION; HUMANS; MUTATION; NEUROMUSCULAR JUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84919645000     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.017137     Document Type: Article

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