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Volumn 77, Issue 4, 2013, Pages 680-695

Spartin Regulates Synaptic Growth and Neuronal Survival by Inhibiting BMP-Mediated Microtubule Stabilization

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR; CELL PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; MEMBRANE PROTEIN; PROTEIN FUTSCH; PROTEIN MAP1B; SPARTIN; UNCLASSIFIED DRUG; VINBLASTINE; WISHFUL THINKING;

EID: 84874253654     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2012.12.015     Document Type: Article
Times cited : (90)

References (50)
  • 1
    • 0037075207 scopus 로고    scopus 로고
    • Wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila
    • Aberle H., Haghighi A.P., Fetter R.D., McCabe B.D., Magalhães T.R., Goodman C.S. wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Neuron 2002, 33:545-558.
    • (2002) Neuron , vol.33 , pp. 545-558
    • Aberle, H.1    Haghighi, A.P.2    Fetter, R.D.3    McCabe, B.D.4    Magalhães, T.R.5    Goodman, C.S.6
  • 3
    • 34248193319 scopus 로고    scopus 로고
    • Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking
    • Bakowska J.C., Jupille H., Fatheddin P., Puertollano R., Blackstone C. Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking. Mol. Biol. Cell 2007, 18:1683-1692.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1683-1692
    • Bakowska, J.C.1    Jupille, H.2    Fatheddin, P.3    Puertollano, R.4    Blackstone, C.5
  • 4
    • 79952068294 scopus 로고    scopus 로고
    • The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases
    • Bayat V., Jaiswal M., Bellen H.J. The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases. Curr. Opin. Neurobiol. 2011, 21:182-188.
    • (2011) Curr. Opin. Neurobiol. , vol.21 , pp. 182-188
    • Bayat, V.1    Jaiswal, M.2    Bellen, H.J.3
  • 5
    • 18244384190 scopus 로고    scopus 로고
    • Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila
    • Bettencourt da Cruz A., Schwärzel M., Schulze S., Niyyati M., Heisenberg M., Kretzschmar D. Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Mol. Biol. Cell 2005, 16:2433-2442.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2433-2442
    • Bettencourt da Cruz, A.1    Schwärzel, M.2    Schulze, S.3    Niyyati, M.4    Heisenberg, M.5    Kretzschmar, D.6
  • 6
    • 21844475890 scopus 로고    scopus 로고
    • Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector
    • Björkblom B., Ostman N., Hongisto V., Komarovski V., Filén J.J., Nyman T.A., Kallunki T., Courtney M.J., Coffey E.T. Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector. J. Neurosci. 2005, 25:6350-6361.
    • (2005) J. Neurosci. , vol.25 , pp. 6350-6361
    • Björkblom, B.1    Ostman, N.2    Hongisto, V.3    Komarovski, V.4    Filén, J.J.5    Nyman, T.A.6    Kallunki, T.7    Courtney, M.J.8    Coffey, E.T.9
  • 7
    • 78650415043 scopus 로고    scopus 로고
    • Hereditary spastic paraplegias: membrane traffic and the motor pathway
    • Blackstone C., O'Kane C.J., Reid E. Hereditary spastic paraplegias: membrane traffic and the motor pathway. Nat. Rev. Neurosci. 2011, 12:31-42.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 31-42
    • Blackstone, C.1    O'Kane, C.J.2    Reid, E.3
  • 8
    • 0037381932 scopus 로고    scopus 로고
    • The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia
    • Ciccarelli F.D., Proukakis C., Patel H., Cross H., Azam S., Patton M.A., Bork P., Crosby A.H. The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia. Genomics 2003, 81:437-441.
    • (2003) Genomics , vol.81 , pp. 437-441
    • Ciccarelli, F.D.1    Proukakis, C.2    Patel, H.3    Cross, H.4    Azam, S.5    Patton, M.A.6    Bork, P.7    Crosby, A.H.8
  • 9
    • 77954843658 scopus 로고    scopus 로고
    • Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P
    • Coffee R.L., Tessier C.R., Woodruff E.A., Broadie K. Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. Dis. Model. Mech. 2010, 3:471-485.
    • (2010) Dis. Model. Mech. , vol.3 , pp. 471-485
    • Coffee, R.L.1    Tessier, C.R.2    Woodruff, E.A.3    Broadie, K.4
  • 10
    • 0014085911 scopus 로고
    • The Troyer syndrome. A recessive form of spastic paraplegia with distal muscle wasting
    • Cross H.E., McKusick V.A. The Troyer syndrome. A recessive form of spastic paraplegia with distal muscle wasting. Arch. Neurol. 1967, 16:473-485.
    • (1967) Arch. Neurol. , vol.16 , pp. 473-485
    • Cross, H.E.1    McKusick, V.A.2
  • 11
    • 64049118343 scopus 로고    scopus 로고
    • A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover
    • Eastman S.W., Yassaee M., Bieniasz P.D. A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover. J. Cell Biol. 2009, 184:881-894.
    • (2009) J. Cell Biol. , vol.184 , pp. 881-894
    • Eastman, S.W.1    Yassaee, M.2    Bieniasz, P.D.3
  • 12
    • 70349780028 scopus 로고    scopus 로고
    • Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5
    • Edwards T.L., Clowes V.E., Tsang H.T., Connell J.W., Sanderson C.M., Luzio J.P., Reid E. Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. Biochem. J. 2009, 423:31-39.
    • (2009) Biochem. J. , vol.423 , pp. 31-39
    • Edwards, T.L.1    Clowes, V.E.2    Tsang, H.T.3    Connell, J.W.4    Sanderson, C.M.5    Luzio, J.P.6    Reid, E.7
  • 13
    • 77952951329 scopus 로고    scopus 로고
    • Activin signaling functions upstream of Gbb to regulate synaptic growth at the Drosophila neuromuscular junction
    • Ellis J.E., Parker L., Cho J., Arora K. Activin signaling functions upstream of Gbb to regulate synaptic growth at the Drosophila neuromuscular junction. Dev. Biol. 2010, 342:121-133.
    • (2010) Dev. Biol. , vol.342 , pp. 121-133
    • Ellis, J.E.1    Parker, L.2    Cho, J.3    Arora, K.4
  • 14
    • 70249136181 scopus 로고    scopus 로고
    • Critical roles for microtubules in axonal development and disease
    • Falnikar A., Baas P.W. Critical roles for microtubules in axonal development and disease. Results Probl. Cell Differ. 2009, 48:47-64.
    • (2009) Results Probl. Cell Differ. , vol.48 , pp. 47-64
    • Falnikar, A.1    Baas, P.W.2
  • 16
    • 77954854166 scopus 로고    scopus 로고
    • Temporal requirements of the fragile x mental retardation protein in modulating circadian clock circuit synaptic architecture
    • Gatto C.L., Broadie K. Temporal requirements of the fragile x mental retardation protein in modulating circadian clock circuit synaptic architecture. Front. Neural Circuits 2009, 3:8.
    • (2009) Front. Neural Circuits , vol.3 , pp. 8
    • Gatto, C.L.1    Broadie, K.2
  • 17
    • 0032502611 scopus 로고    scopus 로고
    • Osteogenic protein-1 and related bone morphogenetic proteins regulate dendritic growth and the expression of microtubule-associated protein-2 in rat sympathetic neurons
    • Guo X., Rueger D., Higgins D. Osteogenic protein-1 and related bone morphogenetic proteins regulate dendritic growth and the expression of microtubule-associated protein-2 in rat sympathetic neurons. Neurosci. Lett. 1998, 245:131-134.
    • (1998) Neurosci. Lett. , vol.245 , pp. 131-134
    • Guo, X.1    Rueger, D.2    Higgins, D.3
  • 18
    • 77952616841 scopus 로고    scopus 로고
    • Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets
    • Hooper C., Puttamadappa S.S., Loring Z., Shekhtman A., Bakowska J.C. Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets. BMC Biol. 2010, 8:72.
    • (2010) BMC Biol. , vol.8 , pp. 72
    • Hooper, C.1    Puttamadappa, S.S.2    Loring, Z.3    Shekhtman, A.4    Bakowska, J.C.5
  • 19
    • 0026643589 scopus 로고
    • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis
    • Jordan M.A., Thrower D., Wilson L. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J. Cell Sci. 1992, 102:401-416.
    • (1992) J. Cell Sci. , vol.102 , pp. 401-416
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 20
    • 79955779955 scopus 로고    scopus 로고
    • SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis
    • Joshi D.C., Bakowska J.C. SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis. PLoS ONE 2011, 6:e19290.
    • (2011) PLoS ONE , vol.6
    • Joshi, D.C.1    Bakowska, J.C.2
  • 21
    • 77949361027 scopus 로고    scopus 로고
    • The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation
    • Kim S., Wairkar Y.P., Daniels R.W., DiAntonio A. The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J. Cell Biol. 2010, 188:717-734.
    • (2010) J. Cell Biol. , vol.188 , pp. 717-734
    • Kim, S.1    Wairkar, Y.P.2    Daniels, R.W.3    DiAntonio, A.4
  • 24
    • 3242693589 scopus 로고    scopus 로고
    • Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth
    • Marie B., Sweeney S.T., Poskanzer K.E., Roos J., Kelly R.B., Davis G.W. Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth. Neuron 2004, 43:207-219.
    • (2004) Neuron , vol.43 , pp. 207-219
    • Marie, B.1    Sweeney, S.T.2    Poskanzer, K.E.3    Roos, J.4    Kelly, R.B.5    Davis, G.W.6
  • 25
    • 0037075180 scopus 로고    scopus 로고
    • The Drosophila BMP type II receptor Wishful Thinking regulates neuromuscular synapse morphology and function
    • Marqués G., Bao H., Haerry T.E., Shimell M.J., Duchek P., Zhang B., O'Connor M.B. The Drosophila BMP type II receptor Wishful Thinking regulates neuromuscular synapse morphology and function. Neuron 2002, 33:529-543.
    • (2002) Neuron , vol.33 , pp. 529-543
    • Marqués, G.1    Bao, H.2    Haerry, T.E.3    Shimell, M.J.4    Duchek, P.5    Zhang, B.6    O'Connor, M.B.7
  • 26
  • 29
    • 0036514504 scopus 로고    scopus 로고
    • Modelling neurodegenerative diseases in Drosophila: a fruitful approach?
    • Muqit M.M., Feany M.B. Modelling neurodegenerative diseases in Drosophila: a fruitful approach?. Nat. Rev. Neurosci. 2002, 3:237-243.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 237-243
    • Muqit, M.M.1    Feany, M.B.2
  • 30
    • 77953786496 scopus 로고    scopus 로고
    • DCIP4 (Drosophila Cdc42-interacting protein 4) restrains synaptic growth by inhibiting the secretion of the retrograde Glass bottom boat signal
    • Nahm M., Kim S., Paik S.K., Lee M., Lee S., Lee Z.H., Kim J., Lee D., Bae Y.C., Lee S. dCIP4 (Drosophila Cdc42-interacting protein 4) restrains synaptic growth by inhibiting the secretion of the retrograde Glass bottom boat signal. J. Neurosci. 2010, 30:8138-8150.
    • (2010) J. Neurosci. , vol.30 , pp. 8138-8150
    • Nahm, M.1    Kim, S.2    Paik, S.K.3    Lee, M.4    Lee, S.5    Lee, Z.H.6    Kim, J.7    Lee, D.8    Bae, Y.C.9    Lee, S.10
  • 31
    • 78049488666 scopus 로고    scopus 로고
    • The Cdc42-selective GAP rich regulates postsynaptic development and retrograde BMP transsynaptic signaling
    • Nahm M., Long A.A., Paik S.K., Kim S., Bae Y.C., Broadie K., Lee S. The Cdc42-selective GAP rich regulates postsynaptic development and retrograde BMP transsynaptic signaling. J. Cell Biol. 2010, 191:661-675.
    • (2010) J. Cell Biol. , vol.191 , pp. 661-675
    • Nahm, M.1    Long, A.A.2    Paik, S.K.3    Kim, S.4    Bae, Y.C.5    Broadie, K.6    Lee, S.7
  • 32
    • 43449130032 scopus 로고    scopus 로고
    • Nervous wreck interacts with thickveins and the endocytic machinery to attenuate retrograde BMP signaling during synaptic growth
    • O'Connor-Giles K.M., Ho L.L., Ganetzky B. Nervous wreck interacts with thickveins and the endocytic machinery to attenuate retrograde BMP signaling during synaptic growth. Neuron 2008, 58:507-518.
    • (2008) Neuron , vol.58 , pp. 507-518
    • O'Connor-Giles, K.M.1    Ho, L.L.2    Ganetzky, B.3
  • 33
    • 27644498533 scopus 로고    scopus 로고
    • Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine
    • Orso G., Martinuzzi A., Rossetto M.G., Sartori E., Feany M., Daga A. Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. J. Clin. Invest. 2005, 115:3026-3034.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3026-3034
    • Orso, G.1    Martinuzzi, A.2    Rossetto, M.G.3    Sartori, E.4    Feany, M.5    Daga, A.6
  • 34
    • 0035940416 scopus 로고    scopus 로고
    • A conditional tissue-specific transgene expression system using inducible GAL4
    • Osterwalder T., Yoon K.S., White B.H., Keshishian H. A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl. Acad. Sci. USA 2001, 98:12596-12601.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12596-12601
    • Osterwalder, T.1    Yoon, K.S.2    White, B.H.3    Keshishian, H.4
  • 36
    • 77950674624 scopus 로고    scopus 로고
    • Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation
    • Podkowa M., Zhao X., Chow C.W., Coffey E.T., Davis R.J., Attisano L. Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation. Mol. Cell. Biol. 2010, 30:2241-2250.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 2241-2250
    • Podkowa, M.1    Zhao, X.2    Chow, C.W.3    Coffey, E.T.4    Davis, R.J.5    Attisano, L.6
  • 37
    • 0037402581 scopus 로고    scopus 로고
    • Drosophila neuromuscular synapse assembly and function require the TGF-beta type I receptor saxophone and the transcription factor Mad
    • Rawson J.M., Lee M., Kennedy E.L., Selleck S.B. Drosophila neuromuscular synapse assembly and function require the TGF-beta type I receptor saxophone and the transcription factor Mad. J. Neurobiol. 2003, 55:134-150.
    • (2003) J. Neurobiol. , vol.55 , pp. 134-150
    • Rawson, J.M.1    Lee, M.2    Kennedy, E.L.3    Selleck, S.B.4
  • 38
    • 67650895049 scopus 로고    scopus 로고
    • Activity-dependent regulation of synapses by retrograde messengers
    • Regehr W.G., Carey M.R., Best A.R. Activity-dependent regulation of synapses by retrograde messengers. Neuron 2009, 63:154-170.
    • (2009) Neuron , vol.63 , pp. 154-170
    • Regehr, W.G.1    Carey, M.R.2    Best, A.R.3
  • 39
    • 77958064894 scopus 로고    scopus 로고
    • SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis
    • Renvoisé B., Parker R.L., Yang D., Bakowska J.C., Hurley J.H., Blackstone C. SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. Mol. Biol. Cell 2010, 21:3293-3303.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 3293-3303
    • Renvoisé, B.1    Parker, R.L.2    Yang, D.3    Bakowska, J.C.4    Hurley, J.H.5    Blackstone, C.6
  • 40
    • 0033136673 scopus 로고    scopus 로고
    • Latheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity
    • Rohrbough J., Pinto S., Mihalek R.M., Tully T., Broadie K. latheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity. Neuron 1999, 23:55-70.
    • (1999) Neuron , vol.23 , pp. 55-70
    • Rohrbough, J.1    Pinto, S.2    Mihalek, R.M.3    Tully, T.4    Broadie, K.5
  • 41
    • 0033710887 scopus 로고    scopus 로고
    • Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth
    • Roos J., Hummel T., Ng N., Klämbt C., Davis G.W. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron 2000, 26:371-382.
    • (2000) Neuron , vol.26 , pp. 371-382
    • Roos, J.1    Hummel, T.2    Ng, N.3    Klämbt, C.4    Davis, G.W.5
  • 42
    • 13944280702 scopus 로고    scopus 로고
    • Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function
    • Sherwood N.T., Sun Q., Xue M., Zhang B., Zinn K. Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol. 2004, 2:e429.
    • (2004) PLoS Biol. , vol.2
    • Sherwood, N.T.1    Sun, Q.2    Xue, M.3    Zhang, B.4    Zinn, K.5
  • 43
    • 0037168108 scopus 로고    scopus 로고
    • Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation
    • Sweeney S.T., Davis G.W. Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation. Neuron 2002, 36:403-416.
    • (2002) Neuron , vol.36 , pp. 403-416
    • Sweeney, S.T.1    Davis, G.W.2
  • 44
    • 3142647116 scopus 로고    scopus 로고
    • The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function
    • Trotta N., Orso G., Rossetto M.G., Daga A., Broadie K. The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr. Biol. 2004, 14:1135-1147.
    • (2004) Curr. Biol. , vol.14 , pp. 1135-1147
    • Trotta, N.1    Orso, G.2    Rossetto, M.G.3    Daga, A.4    Broadie, K.5
  • 46
    • 84934441648 scopus 로고    scopus 로고
    • FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction
    • Verstreken P., Ohyama T., Bellen H.J. FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. Methods Mol. Biol. 2008, 440:349-369.
    • (2008) Methods Mol. Biol. , vol.440 , pp. 349-369
    • Verstreken, P.1    Ohyama, T.2    Bellen, H.J.3
  • 47
    • 33846631991 scopus 로고    scopus 로고
    • Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules
    • Wang X., Shaw W.R., Tsang H.T., Reid E., O'Kane C.J. Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules. Nat. Neurosci. 2007, 10:177-185.
    • (2007) Nat. Neurosci. , vol.10 , pp. 177-185
    • Wang, X.1    Shaw, W.R.2    Tsang, H.T.3    Reid, E.4    O'Kane, C.J.5
  • 48
    • 0033959465 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 enhances dendritic growth and receptivity to innervation in cultured hippocampal neurons
    • Withers G.S., Higgins D., Charette M., Banker G. Bone morphogenetic protein-7 enhances dendritic growth and receptivity to innervation in cultured hippocampal neurons. Eur. J. Neurosci. 2000, 12:106-116.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 106-116
    • Withers, G.S.1    Higgins, D.2    Charette, M.3    Banker, G.4
  • 49
    • 0035977134 scopus 로고    scopus 로고
    • Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
    • Zhang Y.Q., Bailey A.M., Matthies H.J., Renden R.B., Smith M.A., Speese S.D., Rubin G.M., Broadie K. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 2001, 107:591-603.
    • (2001) Cell , vol.107 , pp. 591-603
    • Zhang, Y.Q.1    Bailey, A.M.2    Matthies, H.J.3    Renden, R.B.4    Smith, M.A.5    Speese, S.D.6    Rubin, G.M.7    Broadie, K.8
  • 50
    • 23044515099 scopus 로고    scopus 로고
    • Functions and mechanisms of retrograde neurotrophin signalling
    • Zweifel L.S., Kuruvilla R., Ginty D.D. Functions and mechanisms of retrograde neurotrophin signalling. Nat. Rev. Neurosci. 2005, 6:615-625.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 615-625
    • Zweifel, L.S.1    Kuruvilla, R.2    Ginty, D.D.3


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