Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

Acta Oncologica

Volumn 41, Issue 4, 2002, Pages 352-354

  Hedman, Håkan ^a   Nilsson, Jonas ^a   Guo, Dongsheng ^a   Henriksson, Roger ^a  

^a Oncology ^*  (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CLONING; PROTEINS; TUMORS;

ONCOGENESIS;

GENES;

CELL SURFACE PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN; MESSENGER RNA; PROTEIN KEKKON 1; PROTEIN LRIG1; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CHROMOSOME 3P; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

CHROMOSOMES, HUMAN, PAIR 3; DOWN-REGULATION; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LINKAGE (GENETICS); MEMBRANE GLYCOPROTEINS; NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TUMOR CELLS, CULTURED;

EID: 0036352654     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/028418602760169398     Document Type: Article

References (8)

1. Cloning, characterization, and expression of human LIG1
2. cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains
3. The Drosophila kekkon genes: Novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS
4. The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the drosophila EGF receptor during oogenesis
5. DNA copy number losses in human neoplasms
6. The EGFR family and its ligands in human cancer. Signalling mechanisms and therapeutic opportunities
7. The type III epidermal growth factor receptor mutation