-
1
-
-
49249092223
-
The leucine-rich repeat structure
-
Bella J, Hindle KL, McEwan PA, Lovell SC, (2008) The leucine-rich repeat structure. Cell Mol Life Sci 65: 2307-2333.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2307-2333
-
-
Bella, J.1
Hindle, K.L.2
McEwan, P.A.3
Lovell, S.C.4
-
2
-
-
80054023203
-
Role of leucine-rich repeat proteins in the development and function of neural circuits
-
de Wit J, Hong W, Luo L, Ghosh A, (2011) Role of leucine-rich repeat proteins in the development and function of neural circuits. Annu Rev Cell Dev Biol 27: 697-729.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 697-729
-
-
de Wit, J.1
Hong, W.2
Luo, L.3
Ghosh, A.4
-
3
-
-
39049099153
-
The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns
-
Dolan J, Walshe K, Alsbury S, Hokamp K, O'Keeffe S, et al. (2007) The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genomics 8: 320.
-
(2007)
BMC Genomics
, vol.8
, pp. 320
-
-
Dolan, J.1
Walshe, K.2
Alsbury, S.3
Hokamp, K.4
O'Keeffe, S.5
-
4
-
-
28844473492
-
Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases
-
Matsushima N, Tachi N, Kuroki Y, Enkhbayar P, Osaki M, et al. (2005) Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases. Cell Mol Life Sci 62: 2771-2791.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 2771-2791
-
-
Matsushima, N.1
Tachi, N.2
Kuroki, Y.3
Enkhbayar, P.4
Osaki, M.5
-
5
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B, Kajava AV, (2001) The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol 11: 725-732.
-
(2001)
Curr Opin Struct Biol
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
6
-
-
79952742148
-
Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity
-
Ng AC, Eisenberg JM, Heath RJ, Huett A, Robinson CM, et al. (2011) Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity. Proc Natl Acad Sci U S A 108 Suppl 1: 4631-4638.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.SUPPL. 1
, pp. 4631-4638
-
-
Ng, A.C.1
Eisenberg, J.M.2
Heath, R.J.3
Huett, A.4
Robinson, C.M.5
-
7
-
-
33845882730
-
Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration
-
Maness PF, Schachner M, (2007) Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration. Nat Neurosci 10: 19-26.
-
(2007)
Nat Neurosci
, vol.10
, pp. 19-26
-
-
Maness, P.F.1
Schachner, M.2
-
8
-
-
32244437849
-
The immunoglobulin superfamily of cell adhersion
-
In: Beckerle MC, editor. New York: Oxford University Press
-
Volkmer H (2001) The immunoglobulin superfamily of cell adhersion. In: Beckerle MC, editor. Cell Adhesion. New York: Oxford University Press. pp. 1-29.
-
(2001)
Cell Adhesion
, pp. 1-29
-
-
Volkmer, H.1
-
9
-
-
33746883861
-
AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs
-
Chen Y, Aulia S, Li L, Tang BL, (2006) AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs. Brain Res Rev 51: 265-274.
-
(2006)
Brain Res Rev
, vol.51
, pp. 265-274
-
-
Chen, Y.1
Aulia, S.2
Li, L.3
Tang, B.L.4
-
10
-
-
58149093871
-
Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo
-
Homma S, Shimada T, Hikake T, Yaginuma H, (2009) Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Gene Expr Patterns 9: 1-26.
-
(2009)
Gene Expr Patterns
, vol.9
, pp. 1-26
-
-
Homma, S.1
Shimada, T.2
Hikake, T.3
Yaginuma, H.4
-
11
-
-
4344694204
-
Comparative analysis of the Kekkon molecules, related members of the LIG superfamily
-
MacLaren CM, Evans TA, Alvarado D, Duffy JB, (2004) Comparative analysis of the Kekkon molecules, related members of the LIG superfamily. Dev Genes Evol 214: 360-366.
-
(2004)
Dev Genes Evol
, vol.214
, pp. 360-366
-
-
MacLaren, C.M.1
Evans, T.A.2
Alvarado, D.3
Duffy, J.B.4
-
12
-
-
0033582934
-
The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis
-
Ghiglione C, Carraway KL, (1999) The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. Cell 96: 847-856.
-
(1999)
Cell
, vol.96
, pp. 847-856
-
-
Ghiglione, C.1
Carraway, K.L.2
-
13
-
-
33947651745
-
LRIG inhibitors of growth factor signalling - double-edged swords in human cancer?
-
Hedman H, Henriksson R, (2007) LRIG inhibitors of growth factor signalling- double-edged swords in human cancer? Eur J Cancer 43: 676-682.
-
(2007)
Eur J Cancer
, vol.43
, pp. 676-682
-
-
Hedman, H.1
Henriksson, R.2
-
14
-
-
2942534392
-
The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
-
Guo D, Holmlund C, Henriksson R, Hedman H, (2004) The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea. Genomics 84: 157-165.
-
(2004)
Genomics
, vol.84
, pp. 157-165
-
-
Guo, D.1
Holmlund, C.2
Henriksson, R.3
Hedman, H.4
-
15
-
-
84878598705
-
LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor
-
Wang Y, Poulin EJ, Coffey RJ, (2013) LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor. Br J Cancer 108: 1765-1770.
-
(2013)
Br J Cancer
, vol.108
, pp. 1765-1770
-
-
Wang, Y.1
Poulin, E.J.2
Coffey, R.J.3
-
16
-
-
20844462896
-
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
-
Gur G, Rubin C, Katz M, Amit I, Citri A, et al. (2004) LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. Embo J 23: 3270-3281.
-
(2004)
Embo J
, vol.23
, pp. 3270-3281
-
-
Gur, G.1
Rubin, C.2
Katz, M.3
Amit, I.4
Citri, A.5
-
17
-
-
8744267487
-
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases
-
Laederich MB, Funes-Duran M, Yen L, Ingalla E, Wu X, et al. (2004) The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. J Biol Chem 279: 47050-47056.
-
(2004)
J Biol Chem
, vol.279
, pp. 47050-47056
-
-
Laederich, M.B.1
Funes-Duran, M.2
Yen, L.3
Ingalla, E.4
Wu, X.5
-
18
-
-
84881246735
-
Leucine-rich repeat and immunoglobulin domain-containing protein-1 negative (Lrig1) regulatory action towards ErbB receptor tyrosine kinases is opposed by Leucine-rich repeat and immunoglobulin domain-containing protein-3 (Lrig3)
-
Rafidi H, Mercado F, Astudillo M, Fry WH, Saldana M, et al. (2013) Leucine-rich repeat and immunoglobulin domain-containing protein-1 negative (Lrig1) regulatory action towards ErbB receptor tyrosine kinases is opposed by Leucine-rich repeat and immunoglobulin domain-containing protein-3 (Lrig3). J Biol Chem 288: 21593-605.
-
(2013)
J Biol Chem
, vol.288
, pp. 21593-21605
-
-
Rafidi, H.1
Mercado, F.2
Astudillo, M.3
Fry, W.H.4
Saldana, M.5
-
19
-
-
33747047561
-
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
-
Jensen KB, Watt FM, (2006) Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A 103: 11958-11963.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11958-11963
-
-
Jensen, K.B.1
Watt, F.M.2
-
20
-
-
84859430024
-
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
-
Wong VW, Stange DE, Page ME, Buczacki S, Wabik A, et al. (2012) Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol 14: 401-408.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 401-408
-
-
Wong, V.W.1
Stange, D.E.2
Page, M.E.3
Buczacki, S.4
Wabik, A.5
-
21
-
-
84859196824
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
-
Powell AE, Wang Y, Li Y, Poulin EJ, Means AL, et al. (2012) The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149: 146-158.
-
(2012)
Cell
, vol.149
, pp. 146-158
-
-
Powell, A.E.1
Wang, Y.2
Li, Y.3
Poulin, E.J.4
Means, A.L.5
-
22
-
-
18444370552
-
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia
-
Suzuki Y, Miura H, Tanemura A, Kobayashi K, Kondoh G, et al. (2002) Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett 521: 67-71.
-
(2002)
FEBS Lett
, vol.521
, pp. 67-71
-
-
Suzuki, Y.1
Miura, H.2
Tanemura, A.3
Kobayashi, K.4
Kondoh, G.5
-
23
-
-
33847181657
-
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy
-
Shattuck DL, Miller JK, Laederich M, Funes M, Petersen H, et al. (2007) LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. Mol Cell Biol 27: 1934-1946.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1934-1946
-
-
Shattuck, D.L.1
Miller, J.K.2
Laederich, M.3
Funes, M.4
Petersen, H.5
-
24
-
-
38149041753
-
Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF
-
Ledda F, Bieraugel O, Fard SS, Vilar M, Paratcha G, (2008) Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF. J Neurosci 28: 39-49.
-
(2008)
J Neurosci
, vol.28
, pp. 39-49
-
-
Ledda, F.1
Bieraugel, O.2
Fard, S.S.3
Vilar, M.4
Paratcha, G.5
-
25
-
-
77749258762
-
Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis
-
Abraira VE, Satoh T, Fekete DM, Goodrich LV, (2010) Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis. PLoS One 5: e8981.
-
(2010)
PLoS One
, vol.5
-
-
Abraira, V.E.1
Satoh, T.2
Fekete, D.M.3
Goodrich, L.V.4
-
26
-
-
63449093719
-
Inhibition of LRIG3 gene expression via RNA interference modulates the proliferation, cell cycle, cell apoptosis, adhesion and invasion of glioblastoma cell (GL15)
-
Cai M, Han L, Chen R, Ye F, Wang B, et al. (2009) Inhibition of LRIG3 gene expression via RNA interference modulates the proliferation, cell cycle, cell apoptosis, adhesion and invasion of glioblastoma cell (GL15). Cancer Lett 278: 104-112.
-
(2009)
Cancer Lett
, vol.278
, pp. 104-112
-
-
Cai, M.1
Han, L.2
Chen, R.3
Ye, F.4
Wang, B.5
-
27
-
-
43049116136
-
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways
-
Zhao H, Tanegashima K, Ro H, Dawid IB, (2008) Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development 135: 1283-1293.
-
(2008)
Development
, vol.135
, pp. 1283-1293
-
-
Zhao, H.1
Tanegashima, K.2
Ro, H.3
Dawid, I.B.4
-
28
-
-
60849101584
-
Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear
-
Abraira VE, Del Rio T, Tucker AF, Slonimsky J, Keirnes HL, et al. (2008) Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development 135: 4091-4099.
-
(2008)
Development
, vol.135
, pp. 4091-4099
-
-
Abraira, V.E.1
Del Rio, T.2
Tucker, A.F.3
Slonimsky, J.4
Keirnes, H.L.5
-
29
-
-
68049137882
-
Downregulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro
-
Wang B, Han L, Chen R, Cai M, Han F, et al. (2009) Downregulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro. Cancer Biol Ther 8: 1018-1023.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1018-1023
-
-
Wang, B.1
Han, L.2
Chen, R.3
Cai, M.4
Han, F.5
-
30
-
-
77954472069
-
LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix
-
Hedman H, Lindstrom AK, Tot T, Stendahl U, Henriksson R, et al. (2010) LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix. Acta Oncologica 49: 812-815.
-
(2010)
Acta Oncologica
, vol.49
, pp. 812-815
-
-
Hedman, H.1
Lindstrom, A.K.2
Tot, T.3
Stendahl, U.4
Henriksson, R.5
-
31
-
-
80455137083
-
Association of expression of Leucine-rich repeats and immunoglobulin-like domains 2 gene with invasiveness of pituitary adenoma
-
Zhang H, Yan Q, Xu S, Ou Y, Ye F, et al. (2011) Association of expression of Leucine-rich repeats and immunoglobulin-like domains 2 gene with invasiveness of pituitary adenoma. J Huazhong Univ Sci Technolog Med Sci 31: 520-523.
-
(2011)
J Huazhong Univ Sci Technolog Med Sci
, vol.31
, pp. 520-523
-
-
Zhang, H.1
Yan, Q.2
Xu, S.3
Ou, Y.4
Ye, F.5
-
32
-
-
33645561341
-
Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors
-
Guo D, Nilsson J, Haapasalo H, Raheem O, Bergenheim T, et al. (2006) Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors. Acta Neuropathol (Berl) 111: 238-246.
-
(2006)
Acta Neuropathol (Berl)
, vol.111
, pp. 238-246
-
-
Guo, D.1
Nilsson, J.2
Haapasalo, H.3
Raheem, O.4
Bergenheim, T.5
-
33
-
-
65649148276
-
Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival
-
Holmlund C, Haapasalo H, Yi W, Raheem O, Brannstrom T, et al. (2009) Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival. Neuropathology 29: 242-247.
-
(2009)
Neuropathology
, vol.29
, pp. 242-247
-
-
Holmlund, C.1
Haapasalo, H.2
Yi, W.3
Raheem, O.4
Brannstrom, T.5
-
34
-
-
84873735633
-
LRIG2 mutations cause urofacial syndrome
-
Stuart HM, Roberts NA, Burgu B, Daly SB, Urquhart JE, et al. (2013) LRIG2 mutations cause urofacial syndrome. Am J Hum Genet 92: 259-264.
-
(2013)
Am J Hum Genet
, vol.92
, pp. 259-264
-
-
Stuart, H.M.1
Roberts, N.A.2
Burgu, B.3
Daly, S.B.4
Urquhart, J.E.5
-
36
-
-
69449106560
-
Function and expression pattern of nonsyndromic deafness genes
-
Hilgert N, Smith RJ, Van Camp G, (2009) Function and expression pattern of nonsyndromic deafness genes. Curr Mol Med 9: 546-564.
-
(2009)
Curr Mol Med
, vol.9
, pp. 546-564
-
-
Hilgert, N.1
Smith, R.J.2
Van Camp, G.3
-
37
-
-
84981814856
-
On the development of the membranous labyrinth and the acoustic and facial nerves in the human embryo
-
Streeter GL, (1906) On the development of the membranous labyrinth and the acoustic and facial nerves in the human embryo. American Journal of Anatomy 6: 139-165.
-
(1906)
American Journal of Anatomy
, vol.6
, pp. 139-165
-
-
Streeter, G.L.1
-
38
-
-
0034931033
-
Functional analysis of secreted and transmembrane proteins critical to mouse development
-
Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, et al. (2001) Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet 28: 241-249.
-
(2001)
Nat Genet
, vol.28
, pp. 241-249
-
-
Mitchell, K.J.1
Pinson, K.I.2
Kelly, O.G.3
Brennan, J.4
Zupicich, J.5
-
39
-
-
80053051726
-
Regulation of sodium transport in the inner ear
-
Kim SH, Marcus DC, (2011) Regulation of sodium transport in the inner ear. Hear Res 280: 21-29.
-
(2011)
Hear Res
, vol.280
, pp. 21-29
-
-
Kim, S.H.1
Marcus, D.C.2
-
40
-
-
0025288655
-
Biochemical and morphological differentiation of acetylcholinesterase-positive efferent fibers in the mouse cochlea
-
Emmerling MR, Sobkowicz HM, Levenick CV, Scott GL, Slapnick SM, et al. (1990) Biochemical and morphological differentiation of acetylcholinesterase-positive efferent fibers in the mouse cochlea. J Electron Microsc Tech 15: 123-143.
-
(1990)
J Electron Microsc Tech
, vol.15
, pp. 123-143
-
-
Emmerling, M.R.1
Sobkowicz, H.M.2
Levenick, C.V.3
Scott, G.L.4
Slapnick, S.M.5
-
41
-
-
0038585023
-
LRIG1 protein in human cells and tissues
-
Nilsson J, Starefeldt A, Henriksson R, Hedman H, (2003) LRIG1 protein in human cells and tissues. Cell Tissue Res 312: 65-71.
-
(2003)
Cell Tissue Res
, vol.312
, pp. 65-71
-
-
Nilsson, J.1
Starefeldt, A.2
Henriksson, R.3
Hedman, H.4
-
42
-
-
0033967658
-
Netrin 1 is required for semicircular canal formation in the mouse inner ear
-
Salminen M, Meyer BI, Bober E, Gruss P, (2000) Netrin 1 is required for semicircular canal formation in the mouse inner ear. Development 127: 13-22.
-
(2000)
Development
, vol.127
, pp. 13-22
-
-
Salminen, M.1
Meyer, B.I.2
Bober, E.3
Gruss, P.4
-
44
-
-
77953187849
-
Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling
-
Gumienny TL, Macneil L, Zimmerman CM, Wang H, Chin L, et al. (2010) Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling. PLoS Genet 6: e1000963.
-
(2010)
PLoS Genet
, vol.6
-
-
Gumienny, T.L.1
Macneil, L.2
Zimmerman, C.M.3
Wang, H.4
Chin, L.5
-
45
-
-
0035826256
-
Defining brain wiring patterns and mechanisms through gene trapping in mice
-
Leighton PA, Mitchell KJ, Goodrich LV, Lu X, Pinson K, et al. (2001) Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature 410: 174-179.
-
(2001)
Nature
, vol.410
, pp. 174-179
-
-
Leighton, P.A.1
Mitchell, K.J.2
Goodrich, L.V.3
Lu, X.4
Pinson, K.5
-
46
-
-
84875410552
-
Efferent feedback minimizes cochlear neuropathy from moderate noise exposure
-
Maison SF, Usubuchi H, Liberman MC, (2013) Efferent feedback minimizes cochlear neuropathy from moderate noise exposure. J Neurosci 33: 5542-5552.
-
(2013)
J Neurosci
, vol.33
, pp. 5542-5552
-
-
Maison, S.F.1
Usubuchi, H.2
Liberman, M.C.3
|