Silibinin modulates caudal-type homeobox transcription factor (CDX2), an intestine specific tumor suppressor to abrogate colon cancer in experimental rats

Human and Experimental Toxicology

Volumn 34, Issue 1, 2015, Pages 56-64

  Sangeetha, N ^a,b   Nalini, N ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b SASTRA UNIVERSITY   (India)

Author keywords

Chemoprevention; colon cancer; GCC; mast cell; mucin

Indexed keywords

1,2 DIMETHYLHYDRAZINE; GUANYLATE CYCLASE; GUANYLATE CYCLASE C; MESSENGER RNA; MUCIN; SILIBININ; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ATRIAL NATRIURETIC FACTOR RECEPTOR; CARCINOGEN; CDX2 PROTEIN, RAT; ENTEROTOXIN RECEPTOR; HOMEODOMAIN PROTEIN; RECEPTOR; SILYMARIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; COLON; COLON CANCER; CONTROLLED STUDY; ENDOCRINE CELL; EPITHELIUM CELL; GOBLET CELL; IMMUNOHISTOCHEMISTRY; LYMPH FOLLICLE; MALE; MAST CELL; NONHUMAN; PANETH CELL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBMUCOSA; SUPPLEMENTATION; TUMOR SUPPRESSOR GENE; ANIMAL; CHEMICALLY INDUCED; COLONIC NEOPLASMS; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; WISTAR RAT;

RATTUS;

1,2-DIMETHYLHYDRAZINE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOGENS; COLON; COLONIC NEOPLASMS; HOMEODOMAIN PROTEINS; MALE; RATS; RATS, WISTAR; RECEPTORS, GUANYLATE CYCLASE-COUPLED; RECEPTORS, PEPTIDE; RNA, MESSENGER; SILYMARIN; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84919626116     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327114530741     Document Type: Article

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