Oral supplementation of silibinin prevents colon carcinogenesis in a long term preclinical model

European Journal of Pharmacology

Volumn 643, Issue 1, 2010, Pages 93-100

  Sangeetha, Nagarajan ^a   Aranganathan, Selvaraj ^a   Panneerselvam, Jayabal ^a   Shanthi, Palanivelu ^b   Rama, Gopalan ^b   Nalini, Namasivayam ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Cell proliferation; Chemoprevention; Colon cancer; Glutathione redox system; Preneoplastic lesions; Silibinin

Indexed keywords

1,2 DIMETHYLHYDRAZINE; BETA CATENIN; CYCLIN D1; CYCLINE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; SILIBININ; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CHROMOSOME NOR; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DIET SUPPLEMENTATION; EXPERIMENTAL MODEL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SILVER STAINING; SPECTROPHOTOMETRY;

EID: 77955052581     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.05.060     Document Type: Article

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