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Volumn 5, Issue 4, 2013, Pages 1273-1277

Epigenetic effects of the natural flavonolignan silibinin on colon adenocarcinoma cells and their derived metastatic cells

Author keywords

Colorectal cancer; Combination therapy; DNMT inhibitors; HDAC inhibitors; Silibinin

Indexed keywords

DNA METHYLTRANSFERASE; FLAVONOLIGNAN; HISTONE DEACETYLASE; SILIBININ; TRICHOSTATIN A; VORINOSTAT;

EID: 84874407846     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1190     Document Type: Article
Times cited : (33)

References (22)
  • 2
    • 82955169581 scopus 로고    scopus 로고
    • Epigenetic-based therapies in cancer: Progress to date
    • Song SH, Han SW and Bang YJ: Epigenetic-based therapies in cancer: progress to date. Drugs 71: 2391-2403, 2011.
    • (2011) Drugs , vol.71 , pp. 2391-2403
    • Song, S.H.1    Han, S.W.2    Bang, Y.J.3
  • 3
    • 49349098483 scopus 로고    scopus 로고
    • Histone deacetylaseinhibitors: Mechanisms of cell death and promise in combination cancer therapy
    • Carew JS, Giles FJ and Nawrocki ST: Histone deacetylaseinhibitors: mechanisms of cell death and promise in combination cancer therapy. Cancer Lett 269: 7-17, 2008.
    • (2008) Cancer Lett , vol.269 , pp. 7-17
    • Carew, J.S.1    Giles, F.J.2    Nawrocki, S.T.3
  • 4
    • 42149162792 scopus 로고    scopus 로고
    • HDACs and HDAC inhibitors in colon cancer
    • Mariadason JM: HDACs and HDAC inhibitors in colon cancer. Epigenetics 3: 28-37, 2008.
    • (2008) Epigenetics , vol.3 , pp. 28-37
    • Mariadason, J.M.1
  • 6
    • 54049093249 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Apoptotic effects and clinical implications (Review)
    • Emanuele S, Lauricella M and Tesoriere G: Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review). Int J Oncol 33: 637-646, 2008.
    • (2008) Int J Oncol , vol.33 , pp. 637-646
    • Emanuele, S.1    Lauricella, M.2    Tesoriere, G.3
  • 7
    • 79952262759 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
    • Wagner JM, Hackanson B, Lübbert M and Jung M: Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. Clin Epigenetics 1: 117-136, 2010.
    • (2010) Clin Epigenetics , vol.1 , pp. 117-136
    • Wagner, J.M.1    Hackanson, B.2    Lübbert, M.3    Jung, M.4
  • 8
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA and Baylin SB: The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428, 2002.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 9
  • 10
    • 84867082035 scopus 로고    scopus 로고
    • Epigenetic cancer therapy: Rationales, targets and drugs
    • Rius M and Lyko F: Epigenetic cancer therapy: rationales, targets and drugs. Oncogene 31: 4257-4265, 2012.
    • (2012) Oncogene , vol.31 , pp. 4257-4265
    • Rius, M.1    Lyko, F.2
  • 11
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myöhänen S, Herman JG and Baylin SB: Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21: 103-107, 1999.
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myöhänen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 12
    • 84863011392 scopus 로고    scopus 로고
    • Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases
    • Thakur VS, Gupta K and Gupta S: Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases. Carcinogenesis 33: 377-384, 2012.
    • (2012) Carcinogenesis , vol.33 , pp. 377-384
    • Thakur, V.S.1    Gupta, K.2    Gupta, S.3
  • 13
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W and Yang CS: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63: 7563-7570, 2003.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5    Lu, H.6    Welsh, W.7    Yang, C.S.8
  • 15
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK and Yang CS: Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11: 7033-7041, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 16
    • 83555164704 scopus 로고    scopus 로고
    • Epigenetic CpG demeth ylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells
    • Shu L, Khor TO, Lee JH, Boyanapalli SSS, Huang Y, Wu TY, Saw CL, Cheung KL and Kong AN: Epigenetic CpG demeth ylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells. AAPS J 13: 606-614, 2011.
    • (2011) AAPS J , vol.13 , pp. 606-614
    • Shu, L.1    Khor, T.O.2    Lee, J.H.3    Boyanapalli, S.S.S.4    Huang, Y.5    Wu, T.Y.6    Saw, C.L.7    Cheung, K.L.8    Kong, A.N.9
  • 17
    • 84874038515 scopus 로고    scopus 로고
    • Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells
    • (Epub ahead of print)
    • Yan G, Graham K and Lanza-Jacoby S: Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells. Mol Carcinog Jan 30, 2012 (Epub ahead of print).
    • (2012) Mol Carcinog Jan , vol.30
    • Yan, G.1    Graham, K.2    Lanza-Jacoby, S.3
  • 18
    • 35248859158 scopus 로고    scopus 로고
    • Effects and mechanisms of silibinin on human hepatoma cell lines
    • Lah JJ, Cui W and Hu KQ: Effects and mechanisms of silibinin on human hepatoma cell lines. World J Gastroenterol 13: 5299-5305, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 5299-5305
    • Lah, J.J.1    Cui, W.2    Hu, K.Q.3
  • 19
    • 67651171486 scopus 로고    scopus 로고
    • Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice
    • Cui W, Gu F and Hu KQ: Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World J Gastroenterol 15: 1943-1950, 2009.
    • (2009) World J Gastroenterol , vol.15 , pp. 1943-1950
    • Cui, W.1    Gu, F.2    Hu, K.Q.3
  • 20
    • 84867164315 scopus 로고    scopus 로고
    • Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells
    • Mateen S, Raina K, Jain A, Agarwal C, Chan D and Agarwal R: Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells. Epigenetics 7: 1161-1172, 2012.
    • (2012) Epigenetics , vol.7 , pp. 1161-1172
    • Mateen, S.1    Raina, K.2    Jain, A.3    Agarwal, C.4    Chan, D.5    Agarwal, R.6
  • 21
    • 82955187812 scopus 로고    scopus 로고
    • Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived meta static cells
    • Kauntz H, Bousserouel S, Gossé F and Raul F: Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived meta static cells. Apoptosis 16: 1042-1053, 2011.
    • (2011) Apoptosis , vol.16 , pp. 1042-1053
    • Kauntz, H.1    Bousserouel, S.2    Gossé, F.3    Raul, F.4
  • 22
    • 84864992319 scopus 로고    scopus 로고
    • Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis
    • Kauntz H, Bousserouel S, Gossé F, Marescaux J and Raul F: Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis. Int J Oncol 41: 849-854, 2012.
    • (2012) Int J Oncol , vol.41 , pp. 849-854
    • Kauntz, H.1    Bousserouel, S.2    Gossé, F.3    Marescaux, J.4    Raul, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.